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Cell Line HEK293 Cells Cell Line, Tumor HeLa Cells COS Cells Cells, Cultured Cell Nucleus NIH 3T3 Cells Cytoplasm

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Solvents Proteins Proteasome Endopeptidase Complex Guanidine Water Ubiquitin Ubiquitin-Protein Ligases Urea Muramidase Solutions Recombinant Proteins RNA, Messenger Hexanes Bacterial Proteins Mutant Proteins Acetonitriles Salts Amino Acids DNA-Binding Proteins Nuclear Proteins Transcription Factors Recombinant Fusion Proteins Toluene Leupeptins Tumor Suppressor Protein p53 Dimethylformamide Lysine Proto-Oncogene Proteins c-mdm2 Complex Mixtures Peptides Methanol Acetone Serine Apoproteins Disulfides Proteasome Inhibitors Cysteine Tryptophan Lactalbumin Multiprotein Complexes Carrier Proteins Ribonucleases DNA F-Box Proteins RNA, Small Interfering Membrane Proteins Tumor Suppressor Proteins Organic Chemicals Trichloroethanes Glycogen Synthase Kinase 3 Myoglobin Alanine Repressor Proteins DNA Primers Ligands Cell Cycle Proteins Protein-Serine-Threonine Kinases Methylene Chloride Proline Histidine Peptidylprolyl Isomerase Chloroform Cullin Proteins Proto-Oncogene Proteins c-myc SUMO-1 Protein Hypoxia-Inducible Factor 1, alpha Subunit Chymotrypsinogen Micrococcal Nuclease Dimethyl Sulfoxide Ribonuclease T1 Ubiquitin-Specific Proteases Escherichia coli Proteins Ubiquitins Molecular Chaperones Anilino Naphthalenesulfonates Thermolysin HSP90 Heat-Shock Proteins Ionic Liquids Trans-Activators Methylamines Micelles Saccharomyces cerevisiae Proteins Protein Isoforms Plant Proteins Xylenes Buffers SKP Cullin F-Box Protein Ligases Protein Subunits RNA-Binding Proteins Detergents Multienzyme Complexes Peptide Hydrolases Guanidines Cysteine Endopeptidases Tetrachloroethylene Enzymes Alcohols Ribonuclease, Pancreatic Small Ubiquitin-Related Modifier Proteins Threonine beta-Transducin Repeat-Containing Proteins Macromolecular Substances Sarcosine Trichloroethylene Hypoxia-Inducible Factor-Proline Dioxygenases Azurin Endopeptidases Octanes Protein Synthesis Inhibitors Intracellular Signaling Peptides and Proteins Polymers Ethylene Glycols Cycloheximide RNA

Analytical, Diagnostic and Therapeutic Techniques and Equipment37

Enzyme Stability Drug Stability Protein Denaturation Models, Molecular Circular Dichroism Amino Acid Substitution Protein Engineering Mutagenesis, Site-Directed Protein Unfolding Models, Chemical Calorimetry, Differential Scanning Crystallography, X-Ray Spectrometry, Fluorescence Magnetic Resonance Spectroscopy Molecular Dynamics Simulation Models, Biological Spectrophotometry, Ultraviolet Sequence Alignment Nuclear Magnetic Resonance, Biomolecular Calorimetry Transfection Sequence Analysis, Protein Chromatography, High Pressure Liquid Immunoprecipitation Blotting, Western Two-Hybrid System Techniques Crystallization Immunoblotting Spectrum Analysis Drug Storage Electrophoresis, Polyacrylamide Gel Cloning, Molecular Mass Spectrometry Protein Interaction Mapping Reverse Transcriptase Polymerase Chain Reaction X-Ray Diffraction Gene Knockdown Techniques

Phenomena and Processes83

Protein Stability Enzyme Stability Protein Denaturation Thermodynamics Protein Folding Protein Conformation RNA Stability Amino Acid Sequence Mutation Temperature Protein Structure, Secondary Protein Structure, Tertiary Protein Binding Ubiquitination Proteolysis Amino Acid Substitution Kinetics Hydrogen Bonding Protein Unfolding Hydrogen-Ion Concentration Hot Temperature Binding Sites Static Electricity Half-Life Hydrophobic and Hydrophilic Interactions Structure-Activity Relationship Protein Processing, Post-Translational Solubility Base Sequence Transition Temperature Phosphorylation Mutation, Missense Molecular Dynamics Simulation Amino Acid Motifs Molecular Structure Transcription, Genetic Entropy Gene Expression Regulation Signal Transduction Sequence Homology, Amino Acid Time Factors Physicochemical Phenomena Protein Structure, Quaternary Molecular Conformation Catalysis Point Mutation Transfection Protein Multimerization Dimerization Plasmids Sumoylation Surface Properties Algorithms Catalytic Domain Biophysical Phenomena Protein Transport Substrate Specificity Protein Biosynthesis Mutagenesis Down-Regulation Protein Interaction Domains and Motifs Conserved Sequence Cell Cycle Crystallization Sequence Deletion Genomic Instability Oxidation-Reduction Hydrolysis Osmolar Concentration Phenotype Fluorescence RNA Interference Acetylation Nucleic Acid Conformation DNA Damage Transcriptional Activation Cell Proliferation Glycosylation Apoptosis Promoter Regions, Genetic Gene Expression RNA Processing, Post-Transcriptional X-Ray Diffraction

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Molecular Sequence Data Amino Acid Sequence Computer Simulation Base Sequence Molecular Dynamics Simulation Algorithms Databases, Protein Software

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Temperature Hot Temperature Occupational Exposure

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Solvents Protein Stability Enzyme Stability Drug Stability Protein Denaturation Thermodynamics Protein Folding Models, Molecular Protein Conformation Proteins RNA Stability Molecular Sequence Data Amino Acid Sequence Mutation Temperature Protein Structure, Secondary Circular Dichroism Protein Structure, Tertiary Protein Binding Ubiquitination Proteasome Endopeptidase Complex Proteolysis Guanidine Water Amino Acid Substitution Ubiquitin Protein Engineering Kinetics Hydrogen Bonding Mutagenesis, Site-Directed Protein Unfolding Models, Chemical Calorimetry, Differential Scanning Hydrogen-Ion Concentration Cell Line Hot Temperature Binding Sites Ubiquitin-Protein Ligases Static Electricity Crystallography, X-Ray Urea Muramidase Half-Life Solutions Hydrophobic and Hydrophilic Interactions Escherichia coli Computer Simulation Structure-Activity Relationship Protein Processing, Post-Translational Spectrometry, Fluorescence Recombinant Proteins Solubility Base Sequence HEK293 Cells RNA, Messenger Hexanes Transition Temperature Phosphorylation Bacterial Proteins Mutation, Missense Mutant Proteins Magnetic Resonance Spectroscopy Cell Line, Tumor Molecular Dynamics Simulation Acetonitriles Amino Acid Motifs Salts Amino Acids Molecular Structure DNA-Binding Proteins Transcription, Genetic Entropy Models, Biological Nuclear Proteins Paint Transcription Factors Recombinant Fusion Proteins Chemistry, Physical Toluene Spectrophotometry, Ultraviolet Leupeptins Sequence Alignment Gene Expression Regulation Signal Transduction Sequence Homology, Amino Acid Time Factors Physicochemical Phenomena Tumor Suppressor Protein p53 Protein Structure, Quaternary Nuclear Magnetic Resonance, Biomolecular Molecular Conformation Catalysis Dimethylformamide HeLa Cells Lysine Calorimetry Proto-Oncogene Proteins c-mdm2 Complex Mixtures Point Mutation Transfection

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