Solution crystallization. Medical search. Frequent questions

We demonstrate that a cavitation bubble initiated by a Nd:YAG laser pulse below breakdown threshold induces crystallization from supersaturated aqueous solutions with supersaturation and laser-energy dependent nucleation kinetics. (arxiv.org)
Freeze crystallization (FC) is a melt crystallization method, deﬁned as water removal based on ice formation and its separation from aqueous solutions at or slightly below the freezing point of the solution. (aalto.fi)
The heat transfer during cooling of aqueous solutions (10 wt. (aalto.fi)
Method for recovering anhydrous ZnCl2 from aqueous solutions. (cdc.gov)
8.1 Preparation of aqueous solutions of carbohydrates. (researchandmarkets.com)
8.3 Aqueous solutions of sucrose and glucose syrup. (researchandmarkets.com)
In the initial stage, we used OmpF as a model system due to its high stability, yield and solubility in aqueous solutions to determine the neutron structure at a later stage. (lu.se)

Fusco D, Charbonneau P. Crystallization of asymmetric patchy models for globular proteins in solution . (duke.edu)
The second osmotic virial coefficients of seven proteins - ovalbumin, ribonuclease A, bovine serum albumin, α-lactalbumin, myoglobin, cytochrome c, and catalase - were measured in salt solutions. (umn.edu)
Carrier-driven crystallization can facilitate crystal formation and structure solution of difficult target proteins. (rcsb.org)
In the process of protein crystallization, proteins are dissolved in an aqueous environment and sample solution until they reach the supersaturated state. (wikipedia.org)
Highly ordered states, such as protein crystals, are disfavored thermodynamically compared to more disordered states, such as solutions of proteins in solvent, because the transition to a more ordered state would decrease the total entropy of the system (positive ∆S). For crystals to form spontaneously, the ∆G of crystal formation must be negative. (wikipedia.org)
However, crystallization of some proteins under ambient conditions would both decrease the entropy (positive ∆S) and increase the total energy (positive ∆H) of the system, and thus does not occur spontaneously. (wikipedia.org)
To achieve crystallization of such proteins conditions are modified to make crystal formation energetically favorable. (wikipedia.org)
Crystallization of integral membrane proteins in general continues to be a challenge. (hu-berlin.de)
These proteins are difficult to express, they are highly hydrophobic and therefore require detergent micelles to be stabilized in solution. (hu-berlin.de)
This study screens the influence of extrapallial (EP) proteins from M. edulis on in vitro crystallisation in the laminar flow microfluidic system. (gla.ac.uk)
In order to identify the influence of EP proteins on crystallisation, the total wild-type extrapallial (TWEP) proteins were initially used to produce oval calcite crystals. (gla.ac.uk)
For further investigation, individual purified proteins were used to modify crystallisation, including the wild-type proteins directly extracted from living mussels and the expressed proteins provided from an E.coli expression system. (gla.ac.uk)
Similar structures were also generated in microfluidic channel with the expressed proteins in either CaCl2 solution only or both reagent solutions. (gla.ac.uk)
Multilayer calcite structures were induced in the microfluidic channel in the presence of biomineral proteins, mixed with Na2CO3 solution only. (gla.ac.uk)
All of these results suggest that the extrapallial proteins influence CaCO3 crystallisation. (gla.ac.uk)
1997) at higher how proteins interact with themselves in solution. (lu.se)
Allows a better characterisation of synthetic and natural polymers and proteins in solution. (lu.se)

This paper reports preliminary results on the application of this multi-technique approach to study the crystallization of glycine (which has three known polymorphic forms under ambient conditions) from aqueous solution. (rsc.org)

Polymers, Solutions, Gels and Phase Behavior. (lu.se)

Slow crystallisation speed induces preferential growth in the stable bulk structure, while fast crystallisation leads to the occurrence of a metastable thin-film phase. (rsc.org)

SFC and LFC were applied to concentrate solutions with freezing points in the range from -0.56°C to -7.51°C.The ice nucleation and growth kinetics were inﬂuenced to varying degrees by the solution ideality, undercooling, and initial water concentration in feed solution. (aalto.fi)
This work gives an example of thin film growth where the kinetics during the crystallisation rather than the film thickness is identified as the critical parameter for the presence of a thin-film phase within organic thin films. (rsc.org)

The formation of crystalline substances from solutions or melts. (researchgate.net)
Yes, copper sulphate(CuSO4) can be separated from its solution in crystalline form. (answers.com)
It is well known in the literature that impurities can have wide ranging effects on crystallisation, from delaying the onset of nucleation to modifying the particle morphology and changing the crystalline form. (findaphd.com)
The crystallization is a phenomenon that a crystalline solid of solute is formed out of the solute-dissolved solution or gas via nucleation and growth under a supersaturated condition. (aiche.org)

In 1851, Otto Funke described the process of producing human haemoglobin crystals by diluting red blood cells with solvents, such as pure water, alcohol or ether, followed by slow evaporation of the solvent from the protein solution. (wikipedia.org)
The crystallisation speed is varied by the evaporation rate of the solvent and is identified as a key parameter for the respective polymorphs present in the films. (rsc.org)

SPT LabTech Mosquito nanoliter-scale liquid handlers generate hanging and sitting drop crystallization experiments. (ucla.edu)
Preliminary experiments explore these findings by connecting qualitative crystallization observations to the underpinning transport phenomena facilitating surface rearrangement. (aiche.org)
At the LP3 crystallisation and biophysical laboratory, you can carry out a wide variety of robot-assisted crystallisation experiments in nano volumes as well as screen for a large number of buffer conditions to stabilize their sample. (lu.se)
Allows setting up crystallisation drops with volumes as low as 50 nl protein + 50 nl reservoir and 1-3 protein samples per condition, thus 96-288 experiments can be done in one plate. (lu.se)
Performs automatic imaging of crystallisation experiments at 20 °C using visible and UV light. (lu.se)

In protein crystallization, however, the solute is often expensive or scarce. (the-scientist.com)
In addition, the periodic Taylor vortex aligned the solute molecules in the solution, resulting in the polymorphic nucleation of stable form of the sulfamerazine, which was not possible in the random eddy flow. (aiche.org)
Crystallization is also a chemical solid-liquid separation technique, in which mass transfer of a solute from the liquid solution to a pure solid. (absoluteastronomy.com)
The Urine Osmolality determination is based upon the principle that increased concentration of a solute in a solution causes lowering of its freezing point. (cdc.gov)
A solution containing 1 osmole (1000 mOsm) of dissolved solute per kg of water lowers the freezing point of water by 1.858oC. (cdc.gov)

The solution properties affected the cooling in such a way that the less concentrated the solution was, the faster the undercooling temperature (supersaturation) was reached, and consequently the convective heat transfer coefﬁcient values were higher. (aalto.fi)
Once understood, this mechanism may be better controlled by modifying parameters in the crystallisation process such as seed point and supersaturation control, reducing the need for time consuming extra reworks or chromatography. (findaphd.com)

On the other hand, exactly the same rationale would lead 1 to count on the crystallization of anhydrous magnesium carbonate in FMD when this assumption is extended to Mg dominated circumstances. (faahinhibitor.com)
The process involves high energy requirements for evaporating the pregnant solution to produce anhydrous ZnCl2 needed for electrolytic cell feed. (cdc.gov)

The results explain both why ammonium sulfate is among the best crystallization agents, as well as some of the difficulties that can be encountered in protein crystallization. (umn.edu)
Protein crystallization is the process of formation of a regular array of individual protein molecules stabilized by crystal contacts. (wikipedia.org)
Protein crystallization is governed by the same physics that governs the formation of inorganic crystals. (wikipedia.org)
The two most popular methods for protein crystallization are microbatch and vapor diffusion. (the-scientist.com)

Most industrial processes have to deal with scale, but, in particular, solids that have low solubilities are difficult to manage (because their low solubility means you don't need much of them before crystallization happens). (databasefootball.com)

Crystallisation from solution is a major process by which chemical companies transform synthetic products into solid forms suitable for formulation into commercial products. (findaphd.com)
whilst the study of biomineralisation may lead to new synthetic crystallisation processes. (europa.eu)

In my lab for the last two decades, the principles of the crystallization have been intensively investigated for their applications to the separation of chiral isomers, purification of the bio-products, polymorphs and phase transformation of the active pharmaceutical ingredients, synthesis of nano-particles etc. (aiche.org)

Moreover, it enables separation of sparingly miscible 1-butanol from ABE solutions. (aalto.fi)
Thus, the crystallization technology is frequently used for the separation/purification and particle/powder processes in wide areas of industries. (aiche.org)
This article describes the first observation of crystallization-induced microphase separation in thin film and bulk cellulose triacetate- block -poly(γ-benzyl- l -glutamate) (PBLG) [cellulose triacetate (CTA)- b -PBLG] via copper-catalyzed azide-alkyne cycloaddition (CuAAC) between azido-functionalized CTA at the reducing end and alkyne-functionalized PBLG at the C-terminus. (springer.com)
Charlotta Turner researches the challenge of how to replace organic solvents with supercritical carbon dioxide and pressurized hot water, in separation processes such as extraction, chromatography, and crystallization. (lu.se)

2020. Freeze Concentration of Aqueous [DBNH][OAc] Ionic Liquid Solution. (aalto.fi)

My research is all about understanding how impurities impact crystallization processes and how we can predict their behavior. (databasefootball.com)

2022. Experimental and CFD Study on Influence of Viscosity on Layer Melt Crystallization. (aalto.fi)
Crystallization is the process of formation of solid crystals precipitating from a solution, melt or more rarely deposited directly from a gas. (absoluteastronomy.com)

Crystallization trials are set either following the "classical" vapour diffusion approach or in meso (lipidic cubic phase) using an Oryx 4 crystallization robot (Douglas Instruments). (hu-berlin.de)
Oryx 4 Crystallization Robot (Douglas Instruments Ltd. (hu-berlin.de)

Thus, the obtained ice yields for 60 min of freezing at an undercooling range of 0.83-2.28 °C were:1.3-5.8% for aqueous sucrose solution and 3.6-7.15% for [DBNH][OAc] solutions with 60 min of freezing. (aalto.fi)
8.4 Aqueous sucrose solutions containing invert sugar. (researchandmarkets.com)

Also participating in this research was a group led by Prof. Josep Poblet, Dr. Jorge Carbó, and PhD student Zhong-Ling Lang of the University of Rovira i Virgili, Tarragona, Spain, who assisted in the calculation of the motion of molecules in solution. (sciencedaily.com)
At the nucleation phase, protein molecules in solution come together as aggregates to form a stable solid nucleus. (wikipedia.org)

The crystallization temperature of YSZ increases from 344 to 404 °C as the layer thickness decreases from 15 to 4 nm. (cambridge.org)
The enthalpy of crystallization becomes more exothermic with decreasing thickness, and it was measured to be −26 kJ/mol YSZ for 4-nm-thick layers and −12 kJ/mol for 15-nm-thick layers. (cambridge.org)

The additive can act on the ions in the solution (known as chelating agents), binding them and limiting the amount of solids that form. (databasefootball.com)
Oxalate can bind barium ions in the solution, but is this how it impacts? (databasefootball.com)
So, oxalate is able to inhibit crystallization but not by impacting on the ions in solution (chelation). (databasefootball.com)
These findings are described in the article entitled The impact of oxalate ions on barium sulfate crystallization , recently published in the Journal of Crystal Growth . (databasefootball.com)
Just put, it truly is reasonable to assume that, when the stronger (relative to Ba2 ) hydration of Mg2 dictates that magnesium ions keep largely inside a hydrated kind in aqueous options, the FMD solvation shell around Mg2 is just not as rigid and tight as the hydration shell, permitting for the presence of sufficient level of cost-free magnesium ion to take part in the crystallization reactions. (faahinhibitor.com)
Crystal growth is a major stage of a crystallization process, and consists in the addition of new atoms, ions, or polymer strings into. (absoluteastronomy.com)

We are engaged in a multidisciplinary study of fundamental aspects of the crystallization of organic molecular materials from solution, focusing on polymorphic systems under the recognition that such systems represent an ideal opportunity for obtaining a systematic understanding of competing pathways in crystallization processes. (rsc.org)
Hence, fundamental knowledge on shell secretion and maintenance may generate novel biomimicry and biomimetic solutions to current industrial processes and produce novel bioactive compounds. (europa.eu)

The enthalpy of cold crystallization is typically much smaller than the enthalpy of melting. (researchgate.net)
The latter value is consistent with the reported crystallization enthalpy for YSZ powder of the same composition prepared by precipitation from aqueous solution. (cambridge.org)

Now, researchers at the Weizmann Institute of Science have, for the first time, directly observed the process of crystallization on the molecular level, validating some recent theories about crystallization as well as showing that if one knows how the crystal starts growing, one can predict the end structure. (sciencedaily.com)
In order to avoid this from happening, additives that impact the process of crystallization can be used. (databasefootball.com)

Here, a universal solution-processed bottom-up quasi-epitaxial growth of highly oriented α-formamidinium lead triiodide (α-FAPbI 3 ) perovskite film via a two-step method is reported, in which the crystal orientation of α-FAPbI 3 film is precisely controlled through the synergetic effect of methylammonium chloride and the large-organic cation butylammonium bromide. (edu.hk)
Researchers led by Zhongping Zhang and Suhua Wang, of the Chinese Academy of Sciences' Institute of Intelligent Machines discovered they could coax NaCl and its chemical cousin KCl into the surprising structures when they grew the crystals at the interface of metastable water micro-droplets and an organic solution of cyclohexane and acetone (Angew. (acs.org)

Novel lemon-shaped structures precipitated in the microfluidic channel when the main wild-type 28 kDa extrapallial protein was mixed with CaCl2 solution only. (gla.ac.uk)

But scientists had not been able to observe this process on the molecular level -- that is, the instant in which molecules overcome their tendencies to float individually in a liquid solution and take their place in the rigid lattice of a solid crystal structure. (sciencedaily.com)

The effect of buffer conditions and additives on protein stability can be probed, which is useful in preparation for a crystallisation experiment. (lu.se)

I, II, and III, all with one BPTI molecule per asymmetric unit in solution. (lu.se)

The Professional Preferences Crystallization Inventory (PPCI) is an important instrument which evaluates two dimensions: choosing a career and thus promoting professional development. (bvsalud.org)

formation has come, not from solution studies, but from Whereas theoretical studies of protein self-association are crystallography. (lu.se)

Developing protein crystals is a difficult process influenced by many factors, including pH, temperature, ionic strength in the crystallization solution, and even gravity. (wikipedia.org)

We watch crystallization take place every winter when ice crystals form on our windows. (sciencedaily.com)
Cyclohexane appears to play a critical role in the crystallization because only cubic crystals form when it is absent from the solution. (acs.org)
We argue that monomeric crystals form at high pH despite a high decamer population in solution, because the ion pairs that provide the critical decamer-decamer contacts are disrupted at high pH. (lu.se)

3. Cellulose derivatives carrying a single pyrene group at the reducing-end and fluorescent studies of their self-assembly systems in aqueous NaOH solutions. (springer.com)

The spent solution was treated with calcium hydroxide (Ca(OH)2) at 60 to 80 C for 1 to 4 h to remove remaining zinc and NH3. (cdc.gov)

Adenosine Injection, USP is a sterile solution for rapid bolus intravenous injection. (nih.gov)
After disinfecting, the gutta-percha points were transferred to tubes containing 450 μL of sterile saline solution, homogenized, and diluted. (bvsalud.org)

This new ability to grow salts in unusual shapes could help researchers figure out how to improve control of the crystallization of water-soluble compounds. (acs.org)

Even though this fluid motion was found over 100 years ago, its application to the crystallization was first attempted in my lab to the gas(CO 2 )-liquid(Ca(OH) 2 ) reaction crystallization of calcium carbonate twenty year ago. (aiche.org)
Theory and applications of solution thermodynamics, vapor-liquid and liquid-liquid equilibrium for ideal and non-ideal systems, and chemical reaction equilibrium. (uaeu.ac.ae)
during pre-treatment of the raw material, during the downstream processing of the reaction solution, and lastly when concentrating and purifying the final products. (lu.se)

Zinc diammine chloride (Zn(NH3)2Cl2) was precipitated from solution by adding ammonium chloride (NH4Cl) and sparging with ammonia (NH3) to a pH of 6 to 7.5. (cdc.gov)

4.5 Viscosity of solutions. (researchandmarkets.com)

The slides look a bit sparkly, so maybe some kind of crystallisation has occurred, but under the microscope it looks like a mess of fibres. (researchgate.net)
They then placed the frozen solution under an electron microscope beam that warmed up the mixture just enough to allow some movement -- and, thus, interactions between the molecules. (sciencedaily.com)
Amazingly, we can follow this process as it happens in solution using an atomic force microscope. (databasefootball.com)

We recommend to filter the sample shortly before the crystallization trials starts. (ucla.edu)

7.1 Technical solutions to the problem of mixing. (researchandmarkets.com)

These additives are effective at controlling crystallization at extremely low doses. (databasefootball.com)
AFM and SEM data also demonstrate crystallization inhibition with polymer additives, with concentration-dependent crystal morphology. (aiche.org)

I want to get the latest chemistry news from C&EN in my inbox every week. (acs.org)
The student will learn and apply modern techniques of solid state and solution chemistry to this problem - X-ray diffraction, FTIR, Raman and UV/vis spectroscopy, calorimetry and high throughput experimentation. (findaphd.com)

Atomic force microscopy (AFM) and scanning electron microscopy (SEM) measurements on the evolving interface reveal non-classical and highly anisotropic crystallization. (aiche.org)

Solid-state crystallization at this amorphous drug-water interface is not well understood, nor is the role played by excipients in influencing this crystallization phenomenon. (aiche.org)

Ch requirement for norsethite precipitation in aqueous atmosphere, norsethite can crystallization in Mg-depleted FMD solutions with Mg/Ba = 1/2/5. (faahinhibitor.com)

This mechanism is reproduced here by an aqueous poly(ethylene oxide) (PEO) solution, which solidifies at ambient conditions when subjected to flow. (whiterose.ac.uk)

For crystallization to occur spontaneously, the crystal state must be favored thermodynamically. (wikipedia.org)

Using nanoliter volumes this liquid handling system pipets your optimisation screen directly into the crystallisation plate (pipetting range: 200 nL - 4 mL). (lu.se)

In addition, the combination of computational modelling and real-time crystallisation demonstrates the major influence of the microenvironment on crystal formation along microfluidic channels. (gla.ac.uk)

Organisms7

Diseases2

Chemicals and Drugs28

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Psychiatry and Psychology1

Phenomena and Processes26

Disciplines and Occupations2

Technology, Industry, Agriculture2

Information Science3

Health Care1

Aqueous solutions7

Proteins17

Polymorphic forms1

Polymers1

Induces1

Kinetics2

Crystalline4

Evaporation2

Experiments5

Solute5

Supersaturation2

Anhydrous2

Protein crystallization4

Solubility1

Synthetic2

Polymorphs1

Separation4

20201

Impurities1

Melt2

Robot2

Sucrose2

Molecules in solution2

Thickness2

Ions6

Processes2

Enthalpy2

Process of crystallizat2

Organic2

Structures1

Molecular1

Preparation1

Asymmetric1

Dimensions1

Crystallography1

Ionic1

Crystals form3

NaOH1

Calcium hydroxide1

Sterile2

Compounds1

Reaction3

Ammonium1

Viscosity1

Microscope3

Trials1

Mixing1

Additives2

Chemistry2

Atomic1

Phenomenon1

Precipitation1

Ambient1

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Directly1

Influence1