Freely soluble in waterAqueous solution of piperazineUric acidIntroduced as an anthelminticCitrateDerivativesAnthelmintic actionEthanolPOWDERWaterCompoundsPhosphateHexahydrateMethylOrganicSalineC4H10N2OxidativePharmaceuticalSolvents2017SolventStructuralProductChemicalsChemicalImportantTypesTreatManufacturersIndustrialSideTime
Freely soluble in water2
- Piperazine is freely soluble in water and ethylene glycol, but insoluble in diethyl ether. (wikipedia.org)
- Terazosin hydrochloride is a white, crystalline substance, freely soluble in water and isotonic saline and has a molecular weight of 459.93. (nih.gov)
Aqueous solution of piperazine2
- the pH of a 10% aqueous solution of piperazine is 10.8-11.8. (wikipedia.org)
- It exhibits weak basicity with two pKb values of 5.35 and 9.73 at 25 °C. A 10% aqueous solution of piperazine has a pH range of 10.8-11.8. (ambeed.com)
Uric acid3
- First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 195. (pharmaoffer.com)
- Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. (pharmaoffer.com)
- Although piperazine has an extraordinary ability to dissolve uric acid and create a soluble urate outside of the body, its effectiveness in clinical settings has not been as impressive. (ambeed.com)
Introduced as an anthelmintic1
- Piperazine was first introduced as an anthelmintic in 195. (pharmaoffer.com)
Citrate3
- 6H2O, which melts at 44 °C and boils at 125-130 °C. Two common salts in the form of which piperazine is usually prepared for pharmaceutical or veterinary purposes are the citrate, 3C4H10N2.2C6H8O7 (i.e. containing 3 molecules of piperazine to 2 molecules of citric acid), and the adipate, C4H10N2.C6H10O4 (containing 1 molecule each of piperazine and adipic acid). (wikipedia.org)
- Piperazine hydrate, piperazine adipate and piperazine citrate (used to treat ascariasis and enterobiasis) are the most common anthelmintic piperazine compounds. (wikipedia.org)
- Active Constituents: 50g/L Piperazine Citrate equivalent to 20g/L Piperazine. (vetmedsforpets.com)
Derivatives2
- Although many piperazine derivatives occur naturally, piperazine itself can be synthesized by reacting alcoholic ammonia with 1,2-dichloroethane, by the action of sodium and ethylene glycol on ethylene diamine hydrochloride, or by reduction of pyrazine with sodium in ethanol. (wikipedia.org)
- The invention relates to 1-piperazine- and 1-homopiperazine-carboxylate derivatives, and to the preparation and therapeutic application thereof. (allindianpatents.com)
Anthelmintic action2
- In fact, a large number of piperazine compounds have an anthelmintic action. (wikipedia.org)
- Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism. (pharmaoffer.com)
Ethanol3
- Miscible with wtaer, soluble in ethanol, ether. (dongaochem-metal.com)
- Piperazine hexahydrate is dissolved in ethanol, added with glacial acetic acid, stirred and cooled to precipitate piperazine acetate, which is used to synthesize the hormone drug prednisone sodium phosphate. (dongaochem-metal.com)
- Soluble in DMSO (3 mg/mL), ethanol (7 mg/mL). (lktlabs.com)
POWDER3
- Ketoconazole is a white to slightly beige, odorless powder, soluble in acids, with a molecular weight of 531.44. (nih.gov)
- GEMI is a light brown powder, slight soluble in water, chemically, it is 7-[(4Z)-3(aminomethyl)-4- methoxyimino-pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1, 4dihydro-1, 8-napththyridine-3-carboxylic acid (Figure 1). (biomedres.us)
- TKC is a white to slightly beige, odorless powder that is soluble in acids. (sdrugs.com)
Water8
- Piperazine readily absorbs water and carbon dioxide from the air. (wikipedia.org)
- These products can easily sparingly soluble in water and other solvents. (adanipharma.com)
- The building blocks possess significant stability in basic aqueous solutions, but are easily losing their amino terminal protection upon mild treatment with particular water-soluble bases, e.g. (iris-biotech.de)
- Piperazine dissolves readily in water and ethylene glycol but does not dissolve in diethyl ether. (ambeed.com)
- Wormer gel is a water-soluble worming treatment that can treat several kinds of worm infestations, and can either be mixed in with your pigeon's drinking water or mixed in with their food. (nepigeonsupplies.com)
- The compounds are highly water soluble and can be administered in time release form as well as parenterally, including intravenously. (justia.com)
- It is insoluble in water, easily soluble in organic solvents, and can also be used as an organic solvent itself. (chemenu.com)
- The aim of the present work is to develop and evaluate the solid dispersions (SD) of a poorly water soluble drug bosentan monohydrate (BM). (openpharmaceuticalsciencesjournal.com)
Compounds2
- The piperazines are a broad class of chemical compounds, many with important pharmacological properties, which contain a core piperazine functional group. (wikipedia.org)
- These drugs are often referred to simply as "piperazine" which may cause confusion between the specific anthelmintic drugs, the entire class of piperazine-containing compounds, and the compound itself. (wikipedia.org)
Phosphate2
- Certain types Piperazine Phosphate medicines are present in the market but most of the seller prefer products from the Adani Pharmaceutical industries to sell. (adanipharma.com)
- Effective elimination of round warms and thread warms from the children's bowl is possible with the pripsen piperazine phosphate sachet packs. (adanipharma.com)
Hexahydrate2
- A form in which piperazine is commonly available industrially is as the hexahydrate, C4H10N2. (wikipedia.org)
- Piperazine hexahydrate reacts with acetic anhydride to prepare acetpiperazine, an intermediate of the anthelmintic pipenithiazole. (dongaochem-metal.com)
Methyl2
- Piperazine is also a fluid used for CO2 and H2S scrubbing in association with methyl diethanolamine (MDEA). (wikipedia.org)
- The thermal degradation rates for methyl diethanolamine (MDEA) and piperazine (PZ) are negligible, and PZ, unlike other metals, protect MDEA from oxidative degradation. (wikipedia.org)
Organic3
- Piperazine (/paɪˈpɛrəziːn/) is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring. (wikipedia.org)
- As a soluble synthetic polymer which satisfies the above requirements, an addition polymer obtained by the reaction between a diamine compound having at least one amide bond and an organic diisocyanate compound has been proposed (Japanese Laid-Open Patent Publication No. 58-140737). (justia.com)
- Piperazine is a type of organic compound characterized by a six-membered ring that contains two nitrogen atoms located at opposite positions within the ring. (ambeed.com)
Saline1
- Piperazine exists as small alkaline deliquescent crystals with a saline taste. (wikipedia.org)
C4H10N21
- The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. (chemenu.com)
Oxidative2
- Amine blends that are activated by concentrated piperazine are used extensively in commercial CO2 removal for carbon capture and storage (CCS) because piperazine advantageously allows for protection from significant thermal and oxidative degradation at typical coal flue gas conditions. (wikipedia.org)
- The major identified metabolic pathways are oxidation and degradation of the imidazole and piperazine rings, oxidative Odealkylation and aromatic hydroxylation. (nih.gov)
Pharmaceutical1
- Sienna, piperazine and many other ingredients contained with the pharmaceutical are with pripsen molecules. (adanipharma.com)
Solvents1
- nonetheless, the CO2 absorption rate, heat of absorption, and solvent capacity are increased through the addition of piperazine to amine gas treating solvents, the most common of which is MDEA due to its unmatched high rate and capacity efficiency. (wikipedia.org)
20171
- February 10, 2017 [Main composition] Oxidized polyethylene wax compound with emulsion[General properties] Appearance:yellow translucent thick liquidIonicity: the ionpH: 8 - 10Solubility:soluble in waterStability:stabl. (htfine-chem.com)
Solvent2
- 1) The soluble synthetic polymer is soluble in an appropriate solvent. (justia.com)
- A Pt, Pd, Ag, Cu and/or Ni nanoparticle colloid solution (1) and metal-polymer nanocomposites (2) are prepared by dissolving a salt of the metal and a H 2 O-soluble polymer, such as polyvinyl pyrrolidone, in H 2 O and an alcoholic solvent, purging with N 2 or Ar gas and radiating the solution with radioactive rays. (matthey.com)
Structural1
- studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity. (chemenu.com)
Product2
- Piperazine is formed as a co-product in the ammoniation of 1,2-dichloroethane or ethanolamine. (wikipedia.org)
- The piperazine is separated from the product stream, which contains ethylenediamine, diethylenetriamine, aminoethylpiperazine and other related linear and cyclic chemicals of this type. (wikipedia.org)
Chemicals1
- This is due or soluble proteins could be responsible for the differing skin to the covalent binding to a protein being the essential step that and respiratory-sensitizing abilities of the two chemicals ( 7 ). (cdc.gov)
Chemical1
- Piperazines were originally named because of their chemical similarity with piperidine, part of the structure of piperine in the black pepper plant (Piper nigrum). (wikipedia.org)
Important2
- It is important to note, however, that piperazines are not derived from plants in the Piper genus. (wikipedia.org)
- Among the above-mentioned components, properties of a soluble synthetic polymer are important. (justia.com)
Types1
- Diethylcarbamazine, a derivative of piperazine, is used to treat some types of filariasis. (wikipedia.org)
Treat1
- Piperazine, which is also known as hexahydropyrazine, is an anthelmintic medication that is utilized to treat intestinal roundworm infections in both humans and domestic animals (including poultry). (ambeed.com)
Manufacturers1
- Here you will find a list of producers, manufacturers and traders of Piperazine. (pharmaoffer.com)
Industrial1
- Piperazines are also used in the manufacture of plastics, resins, pesticides, brake fluid and other industrial materials. (wikipedia.org)
Side1
- They provide activity against both gram positive and gram-negative organisms by the virtue of their fluorine and piperazine moieties bearing little side effects [1,2]. (biomedres.us)
Time1
- Piperazine was marketed by Bayer as an anthelmintic in the early 20th century, and was featured in print ads alongside other popular Bayer products at the time, including heroin. (wikipedia.org)