Solid phase microextraction. Medical search. Frequent questions

Solid phase microextraction, or SPME, is a solid phase extraction sampling technique that involves the use of a fiber coated with an extracting phase, that can be a liquid (polymer) or a solid (sorbent), which extracts different kinds of analytes (including both volatile and non-volatile) from different kinds of media, that can be in liquid or gas phase. (wikipedia.org)
ISO 27108:2010 specifies a method for the determination of the dissolved amount of selected plant treatment agents and biocide products in drinking water, ground water and surface water by solid‑phase microextraction (SPME) followed by gas chromatography-mass spectrometry (GC‑MS). The limit of determination depends on the matrix, on the specific compound to be analysed and on the sensitivity of the mass spectrometer. (iso.org)
A rapid, sensitive, and solvent-free procedure for the simultaneous determination of amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine (MDA), and 3,4-methylenedioxymethamphetamine (MDMA) in urine was developed using solid-phase microextraction (SPME) and gas chromatography-mass spectrometry (GC-MS) in the selected ion monitoring mode. (erowid.org)
For the first time, an in vivo sampling mode of direct immersion-solid phase microextraction (DI-SPME) was employed to capture the metabolome of living plant specimens, using apple (Malus × domestica Borkh. (uwaterloo.ca)
Solid-phase microextraction (SPME) has gained widespread acceptance for analyte-matrix separation and preconcentration. (uni-regensburg.de)
Solid phase microextraction , or SPME , is a sample preparation technique used both in the laboratory and on-site. (chemeurope.com)
SPME is a fibre coated with an extracting phase, that can be a liquid ( polymer ) or a solid ( sorbent ), which extracts different kinds of analytes, from volatile to non-volatile, from different kinds of means, that can be in liquid or gas phase. (chemeurope.com)
Liquid phase microextraction (LPME) and solid phase microextraction (SPME) are popular extraction techniques for sample preparation due to their green and highly efficient single-step extraction efficiency. (nih.gov)
Solid Phase Micro Extraction (SPME) is a widely used technique for extraction and concentration of VOCs and SVOCs combined with GC/MS. Unique to absorption techniques for GC, SPME is suited for both small and larger molecules, and the absorption may take place in either the headspace or liquid. (msconsult.dk)
Headspace solid phase microextraction (SPME) was used to extract characteristic odorants collected on the plates. (iastate.edu)
Solid phase microextraction (SPME) is a sub-sample extraction method that has been developed to solve some of the challenges associated with sample preparation as well as to integrate different stages of analysis into one system. (ac.ir)
In this study, three different types of solid phase microextraction (SPME) coatings were produced. (iyte.edu.tr)
Sorptive extraction also called Solid Phase Micro Extraction (SPME) has an adsorbent coated in inert fiber which is placed in the headspace of the sample and adsorbs the volatile compound. (ptmitraayu.com)
In this work, headspace solid-phase microextraction (HS-SPME) was used to identify and quantify terpene content in cannabis. (cannabissciencetech.com)
Headspace solid-phase microextraction (HS-SPME) offers a low cost and easy alternative to traditional headspace methods. (cannabissciencetech.com)
Crosslinked pyrrolidinium-based poly(ionic liquids) (Pyrr-PILs) were synthesized through a fast, simple, and solventless photopolymerization scheme, and tested as solid phase microextraction (SPME) sorbents. (ua.pt)
1997) and are based on solvent extraction or solid phase microextraction (SPME). (cdc.gov)
To mitigating the serious threat of harmful volatile substances to the health of infants , an alternative method of odor evaluation were proposed based on Headspace solid-phase microextraction (HS-SPME) combined with Gas Chromatography-Mass Spectrometry (GC-MS) to discriminate the degree of rancidity of infant formula rice flour (IFRF). (bvsalud.org)
The composition of volatiles emitted by neem seed ( Azadirachta indica L.) and its cake obtained after extraction of oil was analyzed by headspace solid-phase micro extraction (HS-SPME) combined with gas chromatography and gas chromatography- mass spectrometry (GC-MS). Major differences were found in the volatile composition of seed and cake. (upt.ro)
A series of novel ionic liquids (1-(3-aminopropyl)-3-vinyl imidazolium bromide/tetrafluoroborate) grafted onto graphene oxide- coated stainless-steel wires by a sol-gel technique were fabricated and used as solid-phase microextraction (SPME) fibers for the determination of phthalate esters (PAEs) in water and coffee by a direct immersion-SPME-gas chromatography-mass spectrometry (DI-SPME-GC-MS) method. (deu.edu.tr)
Recently, head-space solid-phase microextraction (HS-SPME) has been proposed as an alternative for determining 13 C/ 12 C. The aim of this study was to develop a method to analyse 2 H/ 1 H in vanillin using SPME-GC-IRMS for the first time, by testing different operating conditions and comparing the results with those obtained after solvent extraction. (unitn.it)
In the present study, for the first time, a reliable solid-phase microextraction-gas chromatography-mass spectrometry (SPME-GC-MS) method was developed and validated for the ultra-trace analysis of MF released in growth medium by Daphnia pulex maintained in presence of crowding w/o MK801, a putative upstream inhibitor of MF endogenous production. (unipr.it)
The aim of this work was to address this issue by evaluating automated solid phase micro-extraction (SPME) combined on line with gas chromatography-electron capture negative ionization mass spectrometry (GC/ECNI-MS). Fiber polymer, extraction mode, ionic strength, extraction temperature and time were the most significant thermodynamic and kinetic parameters studied. (univ-amu.fr)
Characterization of agarwood incense using gas chromatography - mass spectrometry (GC-MS) coupled with solid phase micro extraction (SPME) and gas chromatography - flame ionization detector (GC-FID) / Nurlaila Ismail … [et al. (uitm.edu.my)
This paper presents the application of Solid Phase Micro Extraction (SPME) coupled with Gas Chromatography-Mass Spectrometry (GC-MS) and Gas Chromatography-Flame Ionization Detector (GC-FID) to characterize agarwood incense. (uitm.edu.my)
Solid-phase microextraction fibers (SPME) were used for sampling the terpenes and the 2-butanone formation from the hydroxyl reaction with 2-butanol as a measure of OH yields. (cdc.gov)
Solid-phase microextraction (SPME) is a well-known sampling and sample preparation technique used for a wide variety of analytical applications. (uwaterloo.ca)
Solid Phase Microextraction (SPME) is a sampling technique that uses a thin polymer fiber with a hydrophobic coating. (cdc.gov)

A new, simple and rapid procedure for the determination of dimethoate in urine and blood samples was developed using direct immersion solid-phase microextraction and gas chromatography/mass spectrometry. (unboundmedicine.com)
Title : Quantitative Analysis of Menthol in Human Urine Using Solid Phase Microextraction and Stable Isotope Dilution Gas Chromatography/Mass Spectrometry Personal Author(s) : Huang, Wenlin;Blount, Benjamin C.;Watson, Clifford H.;Watson, Christina;Chambers, David M. (cdc.gov)
Discrimination rancidity degree of infant formula rice flour based on Headspace Solid-Phase Microextraction combined with Gas Chromatography-Mass Spectrometry as an alternative to sensory evaluation. (bvsalud.org)
Using headspace solid-phase microextraction followed by gas chromatography mass spectrometry, researchers identified 45 volatile compounds, including ketones and aldehydes. (ift.org)

In this study, reactive thiols were stabilized and the volatile sulfur compounds in milk were extracted by headspace solid-phase microextraction, and analyzed by gas chromatography and pulsed-flame photometric detection. (oregonstate.edu)

Headspace Solid Phase Micro Extraction and GC/MS Analysis of the Volatile Components in Seed and Cake of Azadirachta indica A. juss. (upt.ro)
Owing to the small size, low power, and low gas consumption of DBD-OES as well as efficient extraction of mercury species by porous carbons headspace solid phase micro-extraction, the proposed technique provides several advantages including compactness, cost-effectiveness, and potential to couple with miniature GC to accomplish the field speciation of mercury in rice compared to conventional hyphenated techniques. (canada.ca)

Factors influencing the quantity of the analytes extracted onto the solid-phase micro-extraction fiber, such as addition of salt, sample pH, extraction time, desorption time, and sample volume, were optimized using solid-phase micro-extraction-HPLC-MS/MS. The results showed that the method gave satisfactory sensitivities and precisions for analyzing sub-part-per-trillion levels of triclosan, triclocarban, and transformation products of triclocarban in samples collected locally. (ntnu.edu.tw)

Two absorption type stationary phases: polydimethylsiloxane (PDMS) and polyacrylate (PA) have been found to be most effective for extraction of target analytes. (degruyter.com)
These metabolites are recovered from urine and saliva via extraction, solid phase extraction (SPE), and derivatization with tetrabutylammonium hydroxide before analysis using GC/FPD (Nigg et al. (cdc.gov)

Quantification of trace volatile sulfur compounds in milk by solid-phase microextraction and gas chromatography-pulsed flame photometric detection. (oregonstate.edu)
Twelve natural populations of the species from Trentino-Alto Adige, Italy, were characterized using Headspace-Solid Phase Microextraction analysis for their volatile profile. (agri.gov.il)
Prior to GC-DBD-OES analysis, mercury species were derivatized to their volatile species with NaBPh4 and preconcentrated by headspace solid phase microextraction using porous carbons. (canada.ca)
This type of chemical derivatization results in loss of ionic charge and reduced polarity making each mercury species molecule volatile so that it can escape the liquid phase and accumulate in the gaseous phase ("headspace") directly above the sample. (cdc.gov)

Solid phase microextraction is a powerful and versatile technique, well-suited to the analysis of numerous samples of forensic interest. (purdue.edu)
In a series of research projects, solid phase microextraction was employed for the analysis of explosives, commercial tire treatments, and entomological specimens. (purdue.edu)
The feasibility of this sampling approach, based on exploitation of microextraction principles, including negligible depletion of free analyte concentrations, solventless sampling and sample preparation, and on-site compatibility, was determined in global metabolite analysis. (uwaterloo.ca)
This is a much-used accessory for the analysis of small aldehydes using the oxime formation by PFPBHA reagent, but may be used for all reagents which react fast in the gas phase, e.g. (msconsult.dk)
The method is based on direct acetylation of chlorophenols, solid-phase microextraction of chlorophenyl acetates using poly(dimethylsiloxane)-coated fiber and final analysis of the acetates by GC-MS, 4-bromophenol being used as an internal standard. (chemicke-listy.cz)

Direct immersion solid-phase microextraction has been optimized and applied to the simultaneous determination of the neutral and basic pharmaceuticals: caffeine, carbamazepine, clomipramine, chlorprothixene and clotrimazole at low concentrations in municipal wastewater. (degruyter.com)

Janusz Pawliszyn: Handbook of Solid Phase Microextraction, Chemical Industry Press, 2009. (wikipedia.org)
Pawliszyn J.: Solid Phase Microextraction: Theory and Practice, Wiley-VCH, 1997. (wikipedia.org)
Pawliszyn J.: Applications of Solid Phase Microextraction, Royal Society of Chemistry, 1999. (wikipedia.org)

Both compounds were collected from the transformed N. benthamiana headspace volatiles using solid-phase microextraction. (lu.se)
headspace volatiles using solid-phase microextraction. (lu.se)

The preliminary treatment removes all large and settleable solids from the wastewater. (sigmaaldrich.com)

The high values of distribution coefficient (K fs ) in PDMS/water and PA/water systems (log K fs between 3.05 and 4.23) indicates the very high applicability of these stationary phases for determination of carbamazepine, clomipramine, chlorprothixene and clotrimazole in water samples. (degruyter.com)
Optimization of solid-phase microextraction conditions for determination of phenols. (novapublishers.com)

In this review, starting from a brief description of the recent advances in the last decade, the attention has been focused on the up-to-date research works and applications based on liquid and solid phase microextraction for essential oil analyses. (nih.gov)

NIOSH research has shown that when combined with ozone, one of the common components of pine oil cleaners, alpha-terpineol, transforms into many oxygenated organic compounds in both the gas-phase and on surface reactions creating new products potentially harmful to those exposed. (cdc.gov)

In this research, a metal‐organic framework/polyaniline magnetite nanocomposite was synthesized and intercalated by polyaniline by electrophoretic deposition on the surface of a thin steel wire, to prepare a solid‐phase microextraction fiber. (edu.au)

It uses material from the Wikipedia article "Solid_phase_microextraction" . (chemeurope.com)

Solid Phase Micro-Extraction was used as a solventless means to introduce sufficient mass of sample onto the precolumn of the multi-dimensional system. (gerstel.com)
A simple dispersive solid phase micro-extraction (DSPME) based on activated carbon (AC) was performed for the determination and separation of carcinogenic polycyclic aromatic hydrocarbons (PAHs), namely phenanthrene and fluoranthene, in selected white, brown and parboiled rice samples. (uthm.edu.my)
This review will focus specifically on the state-of-the-art sample pre-treatment methods published in the last ten years including liquid and solid phase micro-extraction, and chip-based manifolds that can be coupled to ICP-MS hyphenated techniques. (rsc.org)

16] M. Mestres, C. Sala, M.P. Martı́, O. Busto, J. Guasch, Headspace solid-phase microextraction of sulphides and disulphides using Carboxen-polydimethylsiloxane fibers in the analysis of wine aroma, Journal of Chromatography A, 835 (1999) 137-144. (jchemlett.com)

Constructed a novel unbreakable solid-phase microextraction fiber by electrodeposition of silica sol-gel on gold (combined inorganic chemistry with electrochemistry). (livecareer.com)
A solventless sample preparation method, invented in 1989, that uses a fused silica fiber which is coated with a stationary phase. (nih.gov)

E. Psillakis, A. Ntelekos, D. Mantzavinos, E.Nikolopoulos, N.Kalogerakis , "Solid-phase microextraction to monitor the sonochemical degradation of polycyclic aromatic hydrocarbons in water " ,J. Environ. (tuc.gr)
Vacuum-assisted headspace thin-film microextraction: Theoretical formulation and method optimization for the extraction of polycyclic aromatic hydrocarbons from water samples. (uwaterloo.ca)

Characterization of three agave species by gas chromatography and solid-phase microextraction-gas chromatography-mass spectrometry. (nih.gov)

Characterization of aroma compounds in apple cider using solvent-assisted flavor evaporation and headspace solid-phase microextraction. (oregonstate.edu)
Vapor intrusion is the vapor phase migration of volatile organic inorganic compounds into indoor air spaces from contaminated groundwater or soil. (sigmaaldrich.com)
Some studies have indicated that most of the toxicity of tobacco smoke is due to gas-phase compounds. (nih.gov)
The kinetics of solid-phase microextraction measured for freshly added and aged hydrophobic compounds in two different soils. (muni.cz)
NIOSH research has shown that when combined with ozone, one of the common components of pine oil cleaners, alpha-terpineol, transforms into many oxygenated organic compounds in both the gas-phase and on surface reactions creating new products potentially harmful to those exposed. (cdc.gov)

12. Headspace solid-phase microextraction for the determination of benzene, toluene, ethylbenzene and xylenes in urine. (nih.gov)

A selectable 1D/2D GC-MS configuration based on Agilent® Technologies capillary flow technology (CFT) and low thermal mass (LTM) GC column modules with dissimilar column phases was used to perform two-dimensional GC analysis of different foodstuffs. (gerstel.com)

In this study, we used anion supramolecular solvent (SUPRAS) prepared from a mixture of an anionic surfactant, sodium dodecyl sulfate (SDS), and a cationic surfactant, tetrabutylammonium bromide (TBABr), as the extraction solvent in liquid phase microextraction (LPME) of paraquat (PQ) and diquat (DQ). (mdpi.com)

Solid-phase microextraction analysis of freshly picked young E. sinica and E. foeminea stems revealed the presence of increased benzaldehyde levels in E. foeminea, whereas 1-phenylpropane-1,2-dione was detected only in E. sinica. (nih.gov)

Polar analytes are attracted to polar phases (e.g., polyacrylate and Carbowax coatings). (sigmaaldrich.com)

Solid phase microextraction of organic pollutants from natural and artificial soils and comparison with bioaccumulation in earthworms. (muni.cz)

When measuring air contaminants, investigators must consider not only the sampling method but also the phase and identity of the pollutant or particulate of interest. (sigmaaldrich.com)

15 glycol ethers can be extracted from water by solid-phase microextraction with a carboxen-polydimethylsiloxane and separated by GC a Carbowax column. (hal.science)

application in thin film solid phase microextraction of anticancer drugs. (bvsalud.org)
Employing a fused deposition modeling (FDM) 3D printer and polylactic acid (PLA) filament, adsorbent films were designed and produced to be utilized in thin film microextraction. (bvsalud.org)

Polybutylene terephthalate-based stationary phase for for ion-pair-free reversed-phase liquid chromatography of small interfering RNA. (uni-tuebingen.de)

Chen, S-H , Device for solid phase microextraction and method for producing the same , Patent No. I385371. (ncku.edu.tw)

The enriched PQ and DQ in the SUPRAS phase were simultaneously analyzed by ion-pairing reversed-phase high performance liquid chromatography. (mdpi.com)
The optimal conditions of ILUAE were determined by single factor experiments and Box-Be hnken design as follows: [C 4 mim]Cl concentration of 0.7 mol/L, extraction time of 4 h, liquid-solid ratio of 15:1 mL/g, ultrasonic power of 195 W, the ultrasonication time of 13 min, and extraction temperature of 48℃·min. (scirp.org)
Samples are mainly prepared by means of liquid-liquid extraction, solid phase extraction, solid phase microextraction, and purge and trap. (epal.pt)

So, the selected 3D printed films with excellent microextraction efficiency have been found to be effective in sample preparation of biological samples. (bvsalud.org)

Venskutonis, R , Leitner, E & Kraujalytė, V 2012, ' Chemical and sensory characterisation of aroma of Viburnum opulus fruits by solid phase microextraction-gas chromatography-olfactometry ', Food Chemistry , vol. 132, no. 2, pp. 717-723. (elsevierpure.com)

Profiling of Unsaturated Lipids by Raman Spectroscopy Directly on Solid-Phase Microextraction Probes. (uwaterloo.ca)

Journal of Non-Crystalline Solids, 366, 1-5. (wku.edu)

2. Lifestyle and occupational factors affecting exposure to BTEX in municipal solid waste composting facility workers. (nih.gov)

The unique sampler design ensures that both the vapor phase and particulate isocyanates are captured and derivatized during sampling. (sigmaaldrich.com)

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