IdiopathicTumoral calcinosisDescribed calcinosis cutisDystrophicThiosulfateSystemic Lupus ErythemCutis circumscriptaUniversalisRaynaudDermatomyositisCRESTConnective tissueMagnesium stearateChlorideInsolubleEtiologyAmorphous calciumRenalOccursCitratePotassiumEtidronateSurgicalOccurClinicalDisordersFatigueConcentrationPatientsProteinResultFormLargeDiseaseTreatment
Idiopathic4
- Calcinosis cutis is classified into 4 major types according to etiology: dystrophic, metastatic, iatrogenic, and idiopathic. (medscape.com)
- 527-530 Dystrophic calcinosis cutis Metastatic calcinosis cutis Iatrogenic calcinosis cutis Traumatic calcinosis cutis Idiopathic calcinosis cutis Idiopathic scrotal calcinosis Subepidermal calcified nodule Tumoral calcinosis Osteoma cutis Intralesional corticosteroids may be beneficial. (wikipedia.org)
- Solitary milialike idiopathic calcinosis cutis: a case unassociated with Down syndrome. (medscape.com)
- Sais G, Jucglà A, Moreno A, Peyrí J. Milia-like idiopathic calcinosis cutis and multiple connective tissue nevi in a patient with Down syndrome. (medscape.com)
Tumoral calcinosis5
- These include calcinosis cutis circumscripta, calcinosis cutis universalis, tumoral calcinosis, and transplant-associated calcinosis cutis. (medscape.com)
- Tumoral calcinosis is more common in blacks of South African heritage. (medscape.com)
- Tumoral calcinosis usually arises in the first or second decade of life. (medscape.com)
- Tumoral calcinosis and calciphylaxis treated with subtotal parathyroidectomy and sodium thiosulphate. (e-jyms.org)
- Tumoral calcinosis (TC) is a condition resulting from extensive calcium phosphate precipitation, primarily in the periarticular tissues around major joints. (e-jyms.org)
Described calcinosis cutis1
- Virchow initially described calcinosis cutis in 1855. (medscape.com)
Dystrophic5
- Dystrophic calcinosis cutis is most common. (medscape.com)
- Marzano AV, Kolesnikova LV, Gasparini G, Alessi E. Dystrophic calcinosis cutis in subacute lupus. (medscape.com)
- DYSTROPHIC CALCINOSIS CUTIS - Dystrophic calcinosis cutis, the most common form of calcinosis cutis, results from local tissue injury. (medilib.ir)
- Treatment principles - The treatment of dystrophic calcinosis cutis associated with autoimmune connective tissue disease is often difficult. (medilib.ir)
- Although early reports documenting poor wound healing and sinus track formation led to the historical avoidance of surgical procedures for dystrophic calcinosis cutis, subsequent reports suggest that surgery can be effective for some patients. (medilib.ir)
Thiosulfate4
- Iatrogenic calcinosis cutis from extravasated phosphate-containing solution treated with topical sodium thiosulfate Xie CB, Kidacki M , Ring N, Panse G, Leventhal JS. (yale.edu)
- Iatrogenic calcinosis cutis from extravasated phosphate-containing solution treated with topical sodium thiosulfate. (yale.edu)
- He underwent subtotal parathyroidectomy, and sodium thiosulfate (STS) was administered for 27 weeks. (e-jyms.org)
- This study is a clinical trial of intravenous sodium thiosulfate, a drug being tested for efficacy and safety in patients who have moderate to extensive calcinosis associated with juvenile and adult dermatomyositis. (nih.gov)
Systemic Lupus Erythem4
- Miteva L, Pramatarov K, Vassileva S. Calcinosis cutis in childhood systemic lupus erythematosus. (medscape.com)
- Extensive calcinosis cutis with systemic lupus erythematosus. (medscape.com)
- Tristano AG, Villarroel JL, Rodriguez MA, Millan A. Calcinosis cutis universalis in a patient with systemic lupus erythematosus. (medscape.com)
- Bullous systemic lupus erythematosus with milia and calcinosis. (medscape.com)
Cutis circumscripta1
- Calcinosis cutis circumscripta tends to arise in the second half of life. (medscape.com)
Universalis2
- Calcinosis cutis universalis occurs in the second decade of life. (medscape.com)
- Calcinosis cutis universalis with joint contractures complicating juvenile dermatomyositis. (medscape.com)
Raynaud1
- A 34-year-old woman with history of scleroderma (CREST variety-ie, calcinosis cutis, Raynaud phenomenon, esophageal motility disorder, sclerodactyly, and telangiectasia) developed dyspnea that worsened upon exertion. (medscape.com)
Dermatomyositis3
- In the setting of dermatomyositis, calcinosis cutis is associated with longer disease duration, fingertip ulcers, and NXP-2 autoantibodies. (medscape.com)
- Calcinosis cutis complicating adult-onset dermatomyositis. (medscape.com)
- Valenzuela A, Chung L, Casciola-Rosen L, Fiorentino D. Identification of clinical features and autoantibodies associated with calcinosis in dermatomyositis. (medscape.com)
CREST1
- In addition, calcinosis is seen in Limited Cutaneous Systemic Sclerosis, also known as CREST syndrome (the "C" in CREST). (wikipedia.org)
Connective tissue2
- Calcinosis may result from a variety of causes such as: Trauma to the region Inflammation (bug bites, acne) Varicose veins Infections Tumors (malignant or benign) Diseases of connective tissue Hypercalcemia Hyperphosphatemia Calcinosis cutis is associated with systemic sclerosis. (wikipedia.org)
- Treatment of calcinosis - Treatment of calcinosis cutis associated with autoimmune connective tissue diseases involves careful consideration of the need for treatment and the selection of an appropriate treatment regimen. (medilib.ir)
Magnesium stearate1
Chloride2
- sodium sulfate/?magnesium sulfate/potassium chloride increases toxicity of etidronate by Other (see comment). (medscape.com)
- This drug exerts the hypotensive effect due to increased excretion of sodium chloride and reduction reactions of vascular smooth muscle to vasoconstrictor effects and by decreasing the BCC. (sdrugs.com)
Insoluble3
- In all cases of calcinosis cutis, insoluble compounds of calcium are deposited within the skin due to local and/or systemic factors. (medscape.com)
- Olsalazine sodium is a yellow crystalline powder, which melts with decomposition at 240°C. It is the sodium salt of a weak acid, soluble in water and DMSO, and practically insoluble in ethanol, chloroform, and ether. (nih.gov)
- INTRODUCTION - The term "calcinosis cutis" describes the deposition of insoluble calcium salts in the skin and subcutaneous tissue. (medilib.ir)
Etiology1
- See "Calcinosis cutis: Etiology and patient evaluation" . (medilib.ir)
Amorphous calcium1
- Tumoural calcinosis (TC) is a rare disorder characterized by nonneoplastic amorphous calcium deposition that tends to occur in soft tissues around the large joint. (biomedcentral.com)
Renal3
- Due to increasing separation of sodium ions occurs secondary increased excretion of water and increased secretion of potassium ions in the distal renal tubule. (sdrugs.com)
- Other: for optional IV injections - thrombophlebitis, renal calcinosis in preterm infants. (sdrugs.com)
- We examined the influence of daily orally iron [sodium ferrous citrate (SFC) iron/tablet 50 mg, 1-2 tablets] on the renal function markers, anemia and iron data for about 6 months. (go.jp)
Occurs2
- Tissue necrosis, ulceration, and secondary infection are the most serious complications.If extravasation occurs or clinical manifestations of calcinosis cutis are noted, immediately discontinue intravenous administration at that site and treat as needed.5.4 Hypotension, Bradycardia, and Cardiac Arrhythmias with Rapid AdministrationRapid injection of Calcium Gluconate Injection may cause vasodilation, decreased blood pressure, bradycardia, cardiac arrhythmias, syncope and cardiac arrest. (drugcentral.org)
- If extravasation occurs or clinical manifestations of calcinosis cutis are noted, immediately discontinue intravenous administration at that site and treat as needed. (drugcentral.org)
Citrate1
- sodium citrate/citric acid decreases levels of etidronate by inhibition of GI absorption. (medscape.com)
Potassium1
- Aldosterone causes sodium and water retention and potassium excretion in the kidneys, leading to arterial hypertension (high blood pressure). (the-medical-dictionary.com)
Etidronate2
- The efficacy of other treatments, such as magnesium or aluminum antacids, sodium etidronate, diphosphonates and diltiazem is unclear, but they have been reported to be serviceable in refractory calcinosis. (wikipedia.org)
- sodium bicarbonate decreases levels of etidronate by inhibition of GI absorption. (medscape.com)
Surgical1
- Surgery - Surgical removal of calcinosis may be useful for patients with discrete, symptomatic areas of calcinosis cutis as the primary treatment or as an adjunct to medical therapy. (medilib.ir)
Occur4
- The pathogenesis of calcinosis cutis is not completely understood and a variety of factors allow for different clinical scenarios to occur. (medscape.com)
- In dogs, calcinosis cutis is found in young, large breed dogs and is thought to occur after a traumatic injury[citation needed]. (wikipedia.org)
- Calcinosis cutis can occur with or without extravasation of Calcium Gluconate Injection, is characterized by abnormal dermal deposits of calcium salts, and clinically manifests as papules, plaques, or nodules that may be associated with erythema, sweling, or induration. (drugcentral.org)
- 4, 5.2)Tissue Necrosis and Calcinosis: Calcinosis cutis can occur with or without extravasation of Calcium Gluconate Injection. (drugcentral.org)
Clinical1
- Clinical follow-up without intervention to reduce calcium deposits is a reasonable option for calcinosis cutis that is asymptomatic, nonprogressive, unassociated with internal involvement, and of minimal concern to the patient. (medilib.ir)
Disorders1
- Calcinosis cutis is a term used to describe a group of disorders in which calcium deposits form in the skin. (medscape.com)
Fatigue1
- Adverse reactions requiring permanent discontinuation in ≥1% of patients were blood creatinine increased, fatigue, subretinal fluid, and calcinosis. (mdtodate.com)
Concentration2
- A 50-fold higher concentration of phosphate was measured in the sodium hyaluronate eye drops used for treatment (50.9 mmol/l) when compared with normal serum. (nih.gov)
- Do not administer Ceftriaxone simultaneously with Calcium Gluconate Injection via Y-site in any age group.5.3 Tissue Necrosis and CalcinosisIntravenous administration of Calcium Gluconate Injection and local trauma may result in calcinosis cutis due to transient increase in local calcium concentration. (drugcentral.org)
Patients2
- The diagnosis and evaluation of patients with calcinosis cutis is discussed separately. (medilib.ir)
- Duration of therapy - Patients who respond to systemic pharmacologic therapies for calcinosis cutis are often maintained on continuous or intermittent treatment for months to years in an attempt to reduce risk for recurrence of disease. (medilib.ir)
Protein1
- The SLC20A2 gene provides instructions for making a protein called sodium-dependent phosphate transporter 2 (PiT-2). (medlineplus.gov)
Result1
- Some infectious granulomas produce 1,25-vitamin D. Infections that may result in calcinosis cutis include onchocerciasis, cysticercosis, histoplasmosis, cryptococcosis, and intrauterine herpes simplex. (medscape.com)
Form1
- Calcinosis cutis is a type of calcinosis wherein calcium deposits form in the skin. (wikipedia.org)
Large1
- This medication violates the reabsorption of sodium and chlorine in the large segment of the ascending loop of Henle. (sdrugs.com)
Disease1
- Tumoural calcinosis (TC) is a rare benign disease that was first named by Inclan and Leon in 1943 [ 1 ]. (biomedcentral.com)
Treatment4
- To report a potential adverse effect of intensified treatment with sodium hyaluronate artificial tears. (nih.gov)
- The treatment of calcinosis cutis is often challenging, and the subtype influences the approach to treatment. (medilib.ir)
- Do the signs and symptoms of calcinosis cutis warrant treatment? (medilib.ir)
- Decision to treat - Consideration of the severity of the signs and symptoms of calcinosis cutis is important because the response to treatment is variable and unpredictable, and there is risk for treatment-related adverse effects. (medilib.ir)