Small studies gametogenesis. Medical search. Frequent questions

Repetitive genome regions are particularly difficult to study with genomic approaches, as they are missing from most genome assemblies. (bvsalud.org)
Recent progress in genome assembly of the sex chromosomes and the availability of population genomic datasets have now made it possible to study divergence and diversity processes of this important region in detail. (biomedcentral.com)
Consequently, PAR1 of humans and great apes is a small genomic region evolving under a concentration of strong population genetic forces. (biomedcentral.com)
The ATM gene and gene product(s) are very large: 3056 amino acids, 350 kDa, a 13-kb transcript (and smaller, alternatively spliced products), and 66 exons that cover 150 kb of genomic DNA. (mhmedical.com)
Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. (genomeweb.com)
DNA methylation plays important roles in many processes like gene expression, genomic imprinting, repression of transposable elements, and gametogenesis. (usda.gov)
Recent genomic DNA studies show that the European eel exhibits isolation by distance, implying that non-random mating and restricted gene flow among eels from different location exists (Ref. 43723 ). (mnhn.fr)

Dictyostelium has been used as a model organism in molecular biology and genetics, and is studied as an example of cell communication, differentiation, and programmed cell death. (wikipedia.org)
Little is known about genetic and phenotypic basis of sex differentiation in oysters, and little more about the molecular pathways regulating reproduction. (univ-brest.fr)
The application of this microarray to the study of mollusk gametogenesis should provide a better understanding of the key factors involved in sex differentiation and the regulation of oyster reproduction. (univ-brest.fr)

Triplicate datasets have been generated for gametogenesis and the results were presented on a poster by PDRA Holly Matthews at the annual Molecular Parasitology Meeting (MPM) in the USA in Sept 2018 (~1.3 years into the project). (europa.eu)
I was mostly interested in the molecular biology surrounding gametogenesis and the pathogenesis of reproductive and developmental disorders. (imperial.ac.uk)
recent molecular studies support this early estimate. (mhmedical.com)
Research is focused on studying the molecular mechanisms involved in the pathogenesis of Vibrio cholerae , the bacterium that causes cholera, and Francisella tularensis , the bacterium that causes tularemia. (utsa.edu)

This study was conducted to evaluate in vivo and in vitro development of in vitro-matured equine oocytes fertilized by intracytoplasmic sperm injection. (bioone.org)
Exome sequencing and in vitro studies identified podocalyxin as a candidate gene for focal and segmental glomerulosclerosis. (genomeweb.com)
Another intriguing area is called in vitro gametogenesis or IVG, where Conception Bio is a leader. (ipscell.com)

METHODOLOGY/PRINCIPAL FINDINGS: Gene expression was studied in gonads of oysters cultured over a yearly reproductive cycle. (univ-brest.fr)
RNA interference (RNAi) includes a diverse set of small RNA-guided gene silencing phenomena. (biomedcentral.com)
Transformation capability will greatly facilitate gene functional studies in C. richardii , more fully realizing the potential of this model fern species. (biomedcentral.com)
A mutation in the nuclear pore complex gene Tmem48 causes gametogenesis defects in skeletal fusions with sterility (sks) mice. (genomeweb.com)

Different biomarker responses were recorded indicating a difference among small mussels in the three study areas, possibly due to differences in growth rates and thus age and reproductive status. (merconsortium.eu)
The vast majority of scleractinian corals broadcast spawn, and consequently spawning corals have been the primary focus for reproductive studies. (sciencematters.io)
Year round gametogenesis is a likely consequence of the year round favourable environmental conditions at these lower-latitude reefs, but with peak reproductive output around the times of broadcast spawning reflecting a common response by corals with different reproductive modes to the cues for reproductive timing. (sciencematters.io)

Gametogenesis in mammals entails profound re-patterning of the epigenome. (biomedcentral.com)
However, due to the lack of accurate male fertility records (i.e., limited mating times), few studies have investigated the comprehensive impacts of sperm DNA methylation on male fertility in mammals. (usda.gov)

These findings have established nuclear RNAi in C. elegans as an important model system to study RNA-mediated chromatin regulation and transgenerational epigenetic inheritance. (biomedcentral.com)

Results: Here, we investigated the relationships between sperm DNA methylation and male fertility in cattle by integrating large-scale (n = 27,214) genome-wide association studies (GWAS) of 35 complex traits (including 12 male fertility traits) and sperm DNA methylation. (usda.gov)

Gametogenesis (the production of spermatozoa and oocytes) and the secretion of hormones by the ovaries and testes are heavily dependent on the hypophysis, a small gland located below the brain, to which it is connected by a capillary network. (sciencedaily.com)

These results and previous studies indicate that mitochondrial proliferation in the cold is a common, but not universal response by different species from different thermal habitats. (nerc.ac.uk)
Since the evolutionary forces driving genetic changes that cause infertility between species are likely also acting within species, the study of hybrid sterility also promises significant insight into mechanisms underlying infertility within species. (elifesciences.org)
In spite of the abundance of research on the roles of TE on the genome biology in humans, model organisms (e.g., mice and Drosophila ), and plants (especially crop species), few studies on TE have been conducted in livestock and poultry. (biomedcentral.com)

[ 9 ] Consequences of an extra X chromosome, usually acquired through a nondisjunctional error during parental gametogenesis, include hypogonadism, gynecomastia, and psychosocial behavioral concerns. (medscape.com)
The major consequences of the extra sex chromosome, usually acquired through an error of nondisjunction during parental gametogenesis, include hypogonadism, gynecomastia, and psychosocial problems. (medscape.com)

Conclusions: Our current study illustrated the important contribution of sperm DNA methylation to the genetic architecture underlying male fertility in cattle and demonstrated the usefulness of functional annotations in enhancing the biological interpretation of GWAS results for complex traits and diseases. (usda.gov)

Klinefelter syndrome is characterized by hypogonadism (micro-orchidism [small testes], oligospermia/azoospermia), gynecomastia in late puberty, hyalinization and fibrosis of the seminiferous tubules, elevated urinary gonadotropin levels, and behavioral concerns. (medscape.com)
In 1942, Klinefelter et al published a report on 9 men who had enlarged breasts, sparse facial and body hair, small testes, and an inability to produce sperm. (medscape.com)

Remarkably little is known about Plasmodium cell cycles, despite a wealth of knowledge on the subject in human cells. (europa.eu)
For example, at the Oceanic Kimberley reefs, groups of corals that include brooders, such as Isopora and Pocilloporidae contribute to approximately 25% of the coral community[4], yet little is known of their cycles of gametogenesis and times of planulae release. (sciencematters.io)

Individual small RNAs are responsible for controlling the expression of gonadoliberin or GnRH (Gonadotropin-Releasing Hormone), a neurohormone that controls sexual maturation, the appearance of puberty, and fertility in adults, new research shows. (sciencedaily.com)
MicroRNAs are small non-coding RNAs transcribed from our DNA. (sciencedaily.com)

Heterothallic sexual development has been most extensively studied in D. discoideum, and homothallic sexual development has been most well studied in D. mucoroides. (wikipedia.org)
Blood parasites belonging to the Apicomplexa, Trypanosomatidae and Filarioidea are widespread in birds and have been studied extensively. (biomedcentral.com)

Our study demonstrated that a large number of the endogenous targets of the germline nuclear RNAi pathway in C. elegans are sensitive to heat-induced transcriptional activation. (biomedcentral.com)

Further studies are needed to determine the mechanisms by which AR affects PIH so that interventions to reduce PIH can be developed to reduce adverse neonatal outcomes associated with ART. (biomedcentral.com)
This study is such a great example of how model systems like fruit flies are essential for understanding fundamental mechanisms of development. (sciencedaily.com)
The Gamblin laboratory studies the mechanisms that lead to the polymerization of the microtubule-associated protein tau. (utsa.edu)
Another area of interest is the study of pathogenic mechanisms of Francisella tularensis , a potential bioweapon, with particular interest in determining how this bacterium evades killing within host macrophages. (utsa.edu)

Timecourses have been conducted to quantify the number and type of replicating nuclei, together with other cell-biological features, in P. falciparum parasites across the course of both erythrocytic schizogony and gametogenesis. (europa.eu)
This study modified, tested and described the buffy coat method (BCM) for quick diagnostics (~ 20 min/sample) of avian blood parasites. (biomedcentral.com)
Its application might be extended to studies of blood parasites in other vertebrates during field studies. (biomedcentral.com)

In this study, we investigated the impact of heat stress on chromatin, transcription, and siRNAs at the whole-genome level, and whether any of the heat-induced effects is transgenerationally heritable in either the wild-type or the germline nuclear RNAi mutant animals. (biomedcentral.com)

Hepatozoon gamonts release from the dog leukocytes within the tick gut and gametogenesis takes place followed by fertilization and sporogony with the formation of oocysts in the tick's hemocoel. (vin.com)

This study also demonstrated that functional annotations can help to explain GWAS results for complex traits and diseases. (usda.gov)

By examining the mRNA, small RNA, RNA polymerase II, and H3K9 trimethylation profiles at the whole-genome level, we revealed an epigenetic role of HRDE-1 in repressing heat stress-induced transcriptional activation of over 280 genes. (biomedcentral.com)
Other recent studies verified the presence of PAPP-A mRNA in granulosa cells of humans, monkeys, cattle, mice, and pigs. (bioone.org)

My laboratory also studies fertility preservation in male cancer patients. (utsa.edu)
Our study detected 16 genes as the most promising candidate genes for male fertility, including SAMD5 and PDE5A. (usda.gov)
Our study reveals how quickly multiple barriers to fertility can arise. (elifesciences.org)

Stereological methods showed that limpet pedal myocytes were 1-2 orders of magnitude smaller in diameter (≈3.5 μm) than in vertebrates, and that the diameter did not vary as a function of temperature. (nerc.ac.uk)

The hypothalamus secretes a small peptide, gonadotropin-releasing. (msdmanuals.com)
During postnatal development, activation of a small number of highly specialised neurons (the GnRH neurons) in the hypothalamus leads to the synthesis of a hormone, gonadoliberin or GnRH (Gonadotropin Releasing Hormone), and this process leads to the appearance of puberty. (sciencedaily.com)

Thus, investigating methylation at intermediate stages would be informative, but genome-wide studies have not yet been done. (biomedcentral.com)
In plants and Schizosaccharomyces pombe , small interfering RNA (siRNA)-directed chromatin modifications (DNA methylation for plants and H3K9 methylation [H3K9me] for S. pombe ) lead to transcriptional repression. (biomedcentral.com)

If you block ring canals, female flies grow tiny, little eggs and can't reproduce. (sciencedaily.com)
In the meiolecithal eggs, the amount of the yolk is very large and it occupies the largest portion of the egg except a small disc-shaped portion of the cytoplasm. (biologydiscussion.com)

METHODS: Eight eyes from four adult male new world monkeys (Cebus apella) were studied. (scielo.br)
We study repeat content and double-strand break hotspot regions in PAR1 and find that they may play roles in ensuring the obligate X-Y recombination event during male meiosis. (biomedcentral.com)
Obligate male crossovers are restricted to this physically small region during male meiosis, so recombination rates per base pair are extremely high, and the region shows high nucleotide diversity. (biomedcentral.com)
Under high population density, later-germinating spores develop into smaller male gametophytes, developing antheridia but not archegonia, in response to the antheridiogen produced by earlier-germinated hermaphrodites [ 6 ]. (biomedcentral.com)
Male gametogenesis (exflagellation) was not affected, but ookinete formation was. (beds.ac.uk)

This study is essential for a wide range of areas in biology and biomedicine, as Dmitrij Dedukh put it. (qs-gen.com)
Our study provides an unprecedented quantification of population genetic forces governing PAR1 biology across extant and extinct hominids. (biomedcentral.com)

In this study, we demonstrate that S-palmitoylation mediated by Erf2-Erf4 and Akr1 palmitoylacyltransferases is required at multiple meiotic stages in the fission yeast Schizosaccharomyces pombe . (life-science-alliance.org)

It represents a unique opportunity to study the dynamics of pericentric heterochromatin, the evolution of associated satellites at a very short time scale, and to better understand how structural variation arises. (bvsalud.org)

In this review, we analyze 72 studies published in the past 20 years, summarize the TE composition in livestock and poultry genomes, and focus on their potential roles in functional genomics. (biomedcentral.com)

Gametogenesis is vulnerable to selfish genetic elements that bias their transmission to the next generation by cheating meiosis. (bvsalud.org)

Cosin, DJD (2003) Gametogenesis and reproduction in Hormogaster elisae (Oligochaeta, Hormogastridae). (ucm.es)
The present study aimed to evaluate S. granularis population in the oligotrophic and narrow insular shelf of Madeira archipelago, mainly regarding its habitat, densities, reproduction season and roe marketable characteristics. (frontiersin.org)
Examination of gonad histology showed a distinct annual pattern in reproduction and the highest levels of roe quality were recorded in the months prior to peak gametogenesis and spawning (i.e. during March, April, May and June of 2014 and 2015). (edu.au)

Previous studies addressed the effects of ecological intensification on the functional diversity of single taxonomic groups in individual countries without considering links between functional diversity and plant, animal or human health across different landscapes and climatic regions. (sav.sk)

Most of our knowledge of nuclear RNAi in animals came from recent studies using C. elegans . (biomedcentral.com)

Results from initial field studies, conducted in Burkina Faso, were very encouraging. (beds.ac.uk)

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. (genomeweb.com)
In the study, the researchers found that an unusually large midbody formed in fruit fly germ cells, stuck around for about 20 to 30 minutes, and then, instead of initiating full separation, underwent dramatic remodeling from a sphere into a ring. (sciencedaily.com)

Our studies use experimental autoimmune encephalomyelitis (EAE) as a model to investigate pathological events related to Multiple Sclerosis. (utsa.edu)
For decades, methodological limitations have restricted the study of infectious diseases to simplified experimental pathosystems in which the influences of host and pathogen diversity and biotic and abiotic environments have been minimized. (nature.com)

Most patients have no measurable ATM (A-T mutated) protein in lysates of their cells or cell lines, while a few have small amounts. (mhmedical.com)

Background: D. melanogaster is increasingly used as a lipid metabolism model, but the D. melanogaster metabolome is not well studied. (usuhs.edu)

Since 2000, there are only 72 studies on TE in livestock and poultry genomes, compared to nearly 1700 studies in humans (PubMed database). (biomedcentral.com)

A number of studies strongly suggest that lipid metabolism is linked to sexual behavior and gametogenesis. (usuhs.edu)

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy. (genomeweb.com)

Repeat-rich regions like pericentric heterochromatin are vulnerable to structural rearrangements although we know little about how often these rearrangements occur over evolutionary time. (bvsalud.org)

Pathological conditions non related to chemical insult can affect gametogenesis as well as on the biomarker responses representing another confounding factor. (merconsortium.eu)

However, this methodology is rather time-consuming for field studies, and this creates obstacles in examining large numbers of animals at the study site in the wild. (biomedcentral.com)

Study outcomes were adverse neonatal outcomes, including premature birth, low birth weight, and admission to the neonatal intensive care unit (NICU). (biomedcentral.com)
This study supports a mediating role for PIH in the association between ART and adverse neonatal outcomes. (biomedcentral.com)

Methods A double-blind study to identify potential ingredients with antimalarial activity from traditional remedies with reported antipyretic properties. (bmj.com)

Mating is initiated by gametogenesis that produces small, motile gametes that fuse to form a small binucleate cell. (wikipedia.org)
Thus, schizogony challenges some basic paradigms about DNA replication control, while gametogenesis demands a speed of DNA replication and cell division that is unprecedented in eukaryotic gametogenesis. (europa.eu)
Aim 1: detailed characterisation, at the whole-cell level, of the asynchronous genome replication that occurs in schizogony and gametogenesis. (europa.eu)
In a new study, researchers uncover how it is that germ cells in fruit flies form these ring canals, a finding that they say will provide new insights into a widely shared feature of development and into diseases in which cell division is disrupted. (sciencedaily.com)
For example, in female fruit flies, ring canals are required to grow a functional oocyte, a developing egg cell," said Lynn Cooley, the C.N.H. Long Professor of Genetics at Yale School of Medicine and senior author of the new study. (sciencedaily.com)
Feeding a cell-free supernatant of bacterial cultures to mosquitoes inhibited oocyst development and passage through a 3kDd filter, while heat treatment and treatment with proteinase K established that the bacteria produced a small, heat stable inhibitor that was not proteinaceous. (beds.ac.uk)

Whether the hormonal control of PAPP-A production/activity by the ovary differs between monotocous and polytocous animals will require further study. (bioone.org)
Farmers, scientist, and policy planners who need improve animal health and production based on genome-enable animal selection will benefit from this study. (usda.gov)

Overall, the most stressed situation was found in both sizes of mussels in the Oslo harbor and large mussels in the Tromsø harbor, while the least stressed were both sizes of mussels in the less impacted site and small mussels from the WWTP site in Trondheim. (merconsortium.eu)
My current interests are directed towards large-scale sequencing and phylogenomic studies investigating major public health threats, such as the causative agents of plague and cholera, Yersinia pestis and Vibrio cholerae , and the dominant cause of food-borne disease in North America, Escherichia coli O157:H7. (utsa.edu)

The staff at Imperial College London are of the highest calibre in their field of study, which is reflected in the excellent standard of teaching and supervision. (imperial.ac.uk)
Publishing on IntechOpen allows authors to earn citations and find new collaborators, meaning more people see your work not only from your own field of study, but from other related fields too. (intechopen.com)

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Phenomena and Processes23

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Species3

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Conclusions1

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Mechanisms4

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