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  • PSORIASIS
  • The Company is present in 65 countries with over 1000 medical sales representatives and is committed to improving the health of skin with an extensive line of products to treat a range of dermatological conditions including: acne, rosacea, fungal nail infections, psoriasis & steroid-responsive dermatoses, pigmentary disorders, skin cancers and medical solutions for skin senescence. (galderma.com)
  • Due to the hyperproliferative action against epidermal cells, S1P has been considered as an active pharmaceutical ingredient for hyperproliferative skin diseases, in particular, psoriasis vulgaris and acne vulgaris. (wikipedia.org)
  • This medication is approved for treatment of psoriasis, acne, and sun damaged skin (photodamage). (wikipedia.org)
  • Tazarotene is most commonly used topically to treat acne, psoriasis (a skin disease in which red, scaly patches form on some areas of the body), and to reduce skin wrinkling and liver spots. (wikipedia.org)
  • papules
  • B) Thesame markers were significantly differently expressed in the inflammatory skin (papules) of the same patients prone to scars and not prone to scars. (jle.com)
  • Steroid acne is an adverse reaction to corticosteroids, and presents as small, firm follicular papules on the forehead, cheeks, and chest. (wikipedia.org)
  • polycystic ovary sy
  • The purpose of this literature review is to evaluate the use of metformin as an adjunct therapy in the treatment of moderate-to-severe acne in those not diagnosed with polycystic ovary syndrome (PCOS). (bioportfolio.com)
  • commensal
  • Skin flora is usually non-pathogenic, and either commensal (are not harmful to their host) or mutualistic (offer a benefit). (wikipedia.org)
  • Naturally, the D. canis mite has a commensal relationship with the dog and therefore under normal conditions does not produce any clinical signs or disease. (wikipedia.org)
  • Tetracycline
  • Tetracycline group are commonly advisable for acne vulgaris. (apply-makeup.info)
  • Minocycline is also used for other skin infections such as MRSA as well as Lyme disease, as the one pill twice daily 100 mg dosage is far easier for patients than the four times a day required with tetracycline or oxytetracycline. (wikipedia.org)
  • bacteria
  • Acne is not caused by dirt but it occurs because of extra oil production, bacteria and inflammation. (apply-makeup.info)
  • In fact, some bacteria previously considered to be nonpathogens are now known to cause disease. (gopetsamerica.com)
  • Finally, some bacteria, such as Lactobacillus acidophilus , are considered to be nonpathogens , because they rarely or never cause human disease. (gopetsamerica.com)
  • It occurs when the pores of the skin become clogged with oil, dead skin cells, and/or bacteria. (encyclopedia.com)
  • The interaction between the body's hormones, skin protein, skin secretions, and bacteria determines the course of acne. (encyclopedia.com)
  • However, acne that is caused by antibiotic resistant bacteria is a growing problem in many countries. (wikipedia.org)
  • Many of them are bacteria of which there are around 1000 species upon human skin from 19 phyla. (wikipedia.org)
  • The benefits bacteria can offer include preventing transient pathogenic organisms from colonizing the skin surface, either by competing for nutrients, secreting chemicals against them, or stimulating the skin's immune system. (wikipedia.org)
  • The estimate of the number of species present on skin bacteria has been radically changed by the use of 16S ribosomal RNA to identify bacterial species present on skin samples direct from their genetic material. (wikipedia.org)
  • However 16S ribosomal RNA research finds that while common, these species make up only 5% of skin bacteria. (wikipedia.org)
  • However, skin variety provides a rich and diverse habitat for bacteria. (wikipedia.org)
  • The umbilicus, or navel, is an area of the body that is rarely exposed to UV light, soaps, or bodily secretions (the navel does not produce any secretions or oils) and because it is an almost undisturbed community of bacteria it is an excellent part of the skin microbiome to study. (wikipedia.org)
  • Treatments
  • However, for acne vulgaris, several recent double blind studies have shown consistently superior efficacy for tazarotene and roughly equal tolerability for both treatments. (wikipedia.org)
  • Treatment
  • Review of orthodox and alternative medicine approach to the treatment of Acne. (wildcrafted.com.au)
  • Below we describe and discuss both western orthodox and traditional (alternative) medical approaches to the treatment and management of Acne. (wildcrafted.com.au)
  • Subjects with acne were randomized to one of four treatment groups for twice daily topical dosing to the face for 12 weeks. (clinicaltrials.gov)
  • The most appropriate treatment is based on the grade and severity of the acne. (medscape.com)
  • Despite an increasing awareness of acne in the adult female population, there is a lack of good prospective studies assessing the severity, distribution, and differential response to treatment in this group. (jcadonline.com)
  • The objective of this article is to review the published data on adult female acne and its treatment, with a particular focus on topical therapy. (jcadonline.com)
  • Recognition and treatment of CLE is important, because it is both a disease in its own right with significant morbidity to those who suffer from it 1 and a potential sign of systemic disease (Table 1). (jddonline.com)
  • The decision by Japan's Ministry of Health, Labor and Welfare is excellent news for patients and physicians in Japan, who will now have access to a first-in-class topical retinoid for the treatment of acne," said Humberto C. Antunes, Chief Executive Officer of Galderma. (galderma.com)
  • With the introduction of Differin ® Gel 0.1% in Japan, Galderma KK, aims to provide comprehensive scientific information to prescribers and medical institutions, with the goal of improving treatment outcomes, as well as the quality of life of Japanese acne patients. (galderma.com)
  • Efficacy, Safety, and Tolerability of Topical Dapsone Gel, 7.5% for Treatment of Acne Vulgaris by Fitzpatrick Skin Phototype. (bioportfolio.com)
  • A topical dermatologic agent that is used in the treatment of ACNE VULGARIS and several other skin diseases. (bioportfolio.com)
  • Many treatment options for acne are available, including lifestyle changes, medications, and medical procedures. (wikipedia.org)
  • Early and aggressive treatment of acne is advocated by some in the medical community to decrease the overall long-term impact to individuals. (wikipedia.org)
  • The severity of acne vulgaris (Gr. ἀκµή, "point" + L. vulgaris, "common") can be classified as mild, moderate, or severe as this helps to determine an appropriate treatment regimen. (wikipedia.org)
  • Minocycline and doxycycline are frequently used for the treatment of acne vulgaris. (wikipedia.org)
  • Historically, minocycline has been a very effective treatment for acne vulgaris. (wikipedia.org)
  • Amoxicillin is recommended as the preferred first-line treatment for community-acquired pneumonia in adults by the National Institute for Health and Care Excellence, either alone (mild to moderate severity disease) or in combination with a macrolide. (wikipedia.org)
  • Amoxicillin is occasionally used for the treatment of skin infections, such as acne vulgaris. (wikipedia.org)
  • It is also used to prevent bacterial endocarditis in high-risk people having dental work done, to prevent Streptococcus pneumoniae and other encapsulated bacterial infections in those without spleens, such as people with sickle-cell disease, and for both the prevention and the treatment of anthrax. (wikipedia.org)
  • In some European countries, the drug has been approved for the treatment of acne vulgaris. (wikipedia.org)
  • During the treatment some patients may develop some adverse effects predominantly of the skin and subcutaneous tissue: burning and itching (in absolute the most common side effect), contact dermatitis, dryness and skin irritation. (wikipedia.org)
  • cutaneous
  • A) Significant difference in expression of cutaneous immunity markers (TLR-4, IL-2 and IL-10) in non- affected skins of patients prone to scars and not prone to scars. (jle.com)
  • commonly
  • Acne commonly appears on the face and shoulders, but may also occur on the trunk, arms, legs, and buttocks. (wildcrafted.com.au)
  • Steroid acne is commonly associated with endogenous or exogenous sources of androgen, drug therapy, or diabetes and is less commonly associated with HIV infection or Hodgkin's disease. (wikipedia.org)
  • The term skin flora (also commonly referred to as skin microbiome) refers to the microorganisms which reside on the skin, typically human skin. (wikipedia.org)
  • lesion
  • Lucky AW, Barber BL, Girman CJ, Williams J, Tatterman J, Waldstreicher J: A multirater validation study to assess the reliability of acne lesion counting. (karger.com)
  • The healing of an acne lesion includes three successive phases . (jle.com)
  • Acne scars are classified based on whether the abnormal healing response following dermal inflammation leads to excess collagen deposition or loss at the site of the acne lesion. (wikipedia.org)
  • Topical
  • The purpose of this study is to evaluate if topical ASC-J9 cream is effective in treating acne. (clinicaltrials.gov)
  • The availability of a topical retinoid in Japan will provide greater flexibility for customizing care and improving outcomes for acne patients. (galderma.com)
  • Following a single topical application of 10 g nadifloxacin 1% cream to normal human back skin, the highest plasma concentration was determined to be 107 ng/mL with an elimination half-life of 19.4 hours. (wikipedia.org)
  • follicles
  • The most common sites of acne are the face, chest, shoulders, and back, since these are the parts of the body where the most sebaceous follicles are found. (encyclopedia.com)
  • Although HS shares certain common features with acne vulgaris, such as a tendency to clog skin follicles with skin cell debris, the condition otherwise lacks the defining features of acne and is therefore considered a distinct skin disorder. (wikipedia.org)
  • clinical
  • Acne vulgaris is a clinical diagnosis. (medscape.com)
  • What is also unclear is whether the clinical distribution of the acne is the same during these two periods or whether teenage acne morphs into another form in the adult female. (jcadonline.com)
  • We undertook the largest acne clinical program ever in Japan, and knew it would be a long journey to approval. (galderma.com)
  • Tretinoin Loaded Nanoemulsion for Acne Vulgaris: Fabrication, Physicochemical and Clinical Efficacy Assessments. (bioportfolio.com)
  • mild
  • Up to 20% of women develop mild acne. (wildcrafted.com.au)
  • Clean your skin gently with a mild, non-drying skin cleanser such as the Skin Renewal Gel . (wildcrafted.com.au)
  • Another unanswered question is whether severity of teenage acne impacts the reporting of recurrence, especially if initial acne was mild and not bothersome. (jcadonline.com)
  • While most studies in the literature report that acne in older women tends to be mild, the members of this group agree that the average patient they see has at least moderate disease. (jcadonline.com)
  • Using non-oily cleansers and mild soap may not cause as much irritation to the skin as regular soap. (wikipedia.org)
  • disorder
  • As acne is a disorder of the pilosebaceous follicle, the inflammation is more often deeply located, in the dermis or in the hypodermis, explaining the development of these scars. (jle.com)
  • scars
  • Expression of innate immunity markers in non-affected and inflammatory skin of patients prone to scars and not prone to scars. (jle.com)
  • Expression of metalloproteinases and their regulators in non-affected and inflammatory skins of patients prone to scars and not prone to scars. (jle.com)
  • A) Significant difference in expression of MMP-9, TIMP-2 and cJUN in non-affected skins of patients prone to scars and not prone to scars. (jle.com)
  • Difference of the profile of innate immunity of uninvolved epidermis between acne patients prone to scars or not. (jle.com)
  • The expression of TLR-4 and at a lesser level TLR-2 are higher in acne patients developing scars. (jle.com)
  • The ratio of cytokines IL-2/ IL-10 is decreased in acne patients developing scars linked both to a decrease of IL-2 and an increase of IL-10. (jle.com)
  • Does Acne produce scars? (theestheticclinic.com)
  • Acne scars are caused by inflammation within the dermal layer of skin and are estimated to affect 95% of people with acne vulgaris. (wikipedia.org)
  • Atrophic acne scars have lost collagen from the healing response and are the most common type of acne scar (account for approximately 75% of all acne scars). (wikipedia.org)
  • Rolling scars are wider than icepick and boxcar scars (4-5 mm across) and have a wave-like pattern of depth in the skin. (wikipedia.org)
  • infections
  • Although it might be tempting to do this, it can lead to scarring and skin infections. (wildcrafted.com.au)
  • They may be the agents of disease (e.g., in patients who have been predisposed to urinary tract infections with Escherichia coli by catheterization). (gopetsamerica.com)
  • It may also be used for strep throat, pneumonia, skin infections, and urinary tract infections among others. (wikipedia.org)
  • It is also used to treat bacterial skin infections. (wikipedia.org)
  • follicle
  • A "whitehead" results when the hair follicle is connected with oil and skin cells. (theestheticclinic.com)
  • In the event that hair follicle wall surface breaks near your skin area, the bump generally becomes a pimple. (theestheticclinic.com)
  • When the follicle begins to bulge and show up as a small whitish bump mostly under the skin, it is called a whitehead. (encyclopedia.com)
  • If the follicle continues to enlarge rather than rupture, it forms a closed sac, called a cyst, which can be felt as a lump under the skin. (encyclopedia.com)
  • It is considered a disease of the hair follicle with biopsy samples showing microscopic changes around the hair follicle. (wikipedia.org)
  • Regular generous applications of moisturising creams cause persistent hydration of the horny layer causing impairment and occlusion of the barrier function, irritation of the hair follicle and proliferation of skin flora. (wikipedia.org)
  • A comedo is a clogged hair follicle (pore) in the skin. (wikipedia.org)
  • Keratin (skin debris) combines with oil to block the follicle. (wikipedia.org)