• While host nerve integration and formation of NMJs were evident within the implanted skeletal muscle constructs, we observed that the constructs did not support the full restoration of defected muscles at 8-week post-implantation, which is likely due to the delayed integration of host nerve. (nature.com)
  • The present work consists of a comparative study of two indexes of skeletal maturation: the carpal index (SMI) and the vertebral index (CVMI) and verification of the reliability of the vertebral index in the determination of the stages of the skeletal maturation. (bvsalud.org)
  • The SMI is the safest and most trustworthy method to evaluate the skeletal maturation, although the CVMI can be used as a substitute method when there is conversance with the morphologic alterations of the vertebrae and when the carpal radiography is not available in the patient's orthodontic records. (bvsalud.org)
  • It is concluded that maturation, testosterone and oestradiol levels play an important role in the physical aspects and performance of motor skills of adolescents, especially in upper limb force which was more related to the maturation obtained by skeletal age of males and females. (bvsalud.org)
  • To determine the predicting the effect of BMI-index percentile on the skeletal maturation of Nigerian children . (bvsalud.org)
  • Main outcome measured Skeletal maturation was assessed using the middle phalanx of the third finger (MP3) while the standard WHO growth chart specific for age (2-20 years) and gender was used for grading BMI-percentile. (bvsalud.org)
  • This study showed that BMI-percentile is a weak predictor of skeletal maturation. (bvsalud.org)
  • However, obese children had a tendency towards advanced skeletal maturation than healthy participants . (bvsalud.org)
  • CHST3 -related skeletal dysplasia is a genetic condition characterized by bone and joint abnormalities that worsen over time. (medlineplus.gov)
  • Recently, researchers have proposed the umbrella term CHST3 -related skeletal dysplasia to refer to bone and joint abnormalities resulting from mutations in the CHST3 gene. (medlineplus.gov)
  • A shortage of this enzyme disrupts the normal development of cartilage and bone, resulting in the abnormalities associated with CHST3 -related skeletal dysplasia. (medlineplus.gov)
  • Embark on a bone-chilling quest for vengeance as a skull-hurling skeletal warrior in Skeletal Avenger! (steampowered.com)
  • Skeletal dysplasias, also known as osteochondrodysplasias, are a heterogeneous group of heritable disorders characterized by abnormalities of cartilage and bone growth, resulting in abnormal shape and size of the skeleton and disproportion of the long bones, spine, and head. (medscape.com)
  • Pair with the right makeup (not included) and you'll be one stunning skeletal bone mistress walking amongst the living once again! (michaels.com)
  • An understanding of the human skeletal system, including the nature and function of bone, the identification of bone and bony fragments in an anthropological context, and the interpretation of morphological features of bone for research in biological anthropology and human biology. (kent.ac.uk)
  • It's also the main part of the bone that lends firmness and support to your skeletal system. (webmd.com)
  • A computational model calculates 'skeletal age', predicting someone's risk of bone fracture and premature death. (prohealth.com)
  • Researchers at the Garvan Institute of Medical Research have developed a computational model to calculate 'skeletal age', a personalised estimate of an individual's risk of bone fracture and premature death. (prohealth.com)
  • The skeletal age calculator, which will be accessible to doctors and health professionals, aims to better identify those at risk of a first bone fracture and subsequent fractures, and also estimates how fractures impact life expectancy. (prohealth.com)
  • A number of recent studies, for example, have found that heavy tea drinkers can develop skeletal fluorosis - a bone disease caused by excessive intake of fluoride. (fluoridealert.org)
  • Appreciation of the significant amounts of F in some modern preparations of tea suggested to us that [skeletal fluorosis] caused our patient's high bone mass when she recounted her remarkable volume of instant tea consumed over three decades. (fluoridealert.org)
  • Determining the skeletal bone age is necessary in a variety of fields, ranging from pediatric radiology and endocrinology to crime investigation. (actapress.com)
  • Indeed, assessing the skeletal bone age is useful in situations like when developmental delays are present, in order to search for an organic cause, or when human age must be identified and no other evidence exists. (actapress.com)
  • The study , published May 11 in the peer-reviewed journal Cell Stem Cell, identified various cell types present in skeletal muscle tissues, from early embryonic development all the way to adulthood. (scienceblog.com)
  • Also, a vascularization strategy using co-culture with endothelial cells (ECs) and fibroblasts improved the survival of the bioengineered skeletal muscle tissues 20 , 21 . (nature.com)
  • The contraction or extension of the skeletal muscles causes the attached bones forming joints to move either by flexing or extending. (microscopyu.com)
  • Dear Reader: Myasthenia gravis is a long-term disease that adversely affects the skeletal muscles. (uclahealth.org)
  • Skeletal muscles are known as voluntary muscles, which means they are under a person's direct control. (uclahealth.org)
  • When someone has myasthenia gravis, their skeletal muscles become weak and quickly grow fatigued when in use. (uclahealth.org)
  • Typified by short stature (defined as height that is three or more standard deviations below the mean height for age), skeletal dysplasias can be accompanied by involvement of other systems, including the neurologic, respiratory, and cardiac systems. (medscape.com)
  • While I've yet to see how well the full game's missions and side-quests stack up, Skeletal Dance Party feels like just the kind of cheerful villainy we need for this final stretch of Skeleton Appreciation Month. (rockpapershotgun.com)
  • We define skeletal age as the age of an individual's skeleton that results from their risk factors for fracture," explains Professor Nguyen. (prohealth.com)
  • In Skeletal Avenger, no two runs are alike. (steampowered.com)
  • Dare to defy the odds and dive headfirst into the dark, immersive world of Skeletal Avenger. (steampowered.com)
  • Skeletal Avenger is a hack'n'slash roguelite with a massive perk arsenal and head-chucking special moves! (gog.com)
  • Coxa vara can be a progressive deformity in children with skeletal dysplasia. (nih.gov)
  • Funai and colleagues found that during weight loss in obese mice, the efficiency of skeletal muscle mitochondrial oxidative phosphorylation increased, resulting in a reduction in energy expenditure throughout the body, which in turn contributes to weight loss rebound. (news-medical.net)
  • The results showed that there was no significant change in mitochondrial proteomes or respiratory chain supercomplex formation in skeletal muscle of weight-loss mice, but oxidative phosphorylation efficiency significantly increased. (news-medical.net)
  • Further studies showed that knocking down CL acyltransferase tafazzin reduced TLCL levels as well as skeletal muscle oxidative phosphorylation levels, allowing mice to avoid diet-induced weight gain. (news-medical.net)
  • Compared with Sprague-Dawley normtensive control rats, Ren-2 skeletal muscle exhibited significantly increased oxidative stress, NF-ĸB activation, and TNF-α expression, which were attenuated by in vivo treatment with an angiotensin type 1 receptor blocker (valsartan) or SOD/catalase mimetic (tempol). (biosyn.com)
  • [ 4-6 ] Although the mechanisms are poorly understood, statins have been shown to reduce muscle mitochondrial oxidative capacity and content in humans [ 7-10 ] and impair exercise-mediated mitochondrial adaptations in skeletal muscle. (medscape.com)
  • A vertebral skeletal stem cell lineage driving metastasis. (bvsalud.org)
  • Here we identify a vertebral skeletal stem cell (vSSC) that co-expresses ZIC1 and PAX1 together with additional cell surface markers. (bvsalud.org)
  • Together, our results indicate that vSSCs are distinct from other skeletal stem cells and mediate the unique physiology and pathology of vertebrae , including contributing to the high rate of vertebral metastasis . (bvsalud.org)
  • Although this phenomenon has long been identified and has been suggested that weight loss may alter skeletal muscle mitochondrial respiration, the mechanisms are not fully understood and direct evidence is lacking. (news-medical.net)
  • In April 2023, Professor Katsuhiko Funai at University of Utah published a study in Life Metabolism entitled 'Weight loss increases skeletal muscle mitochondrial energy efficiency in obese mice'(DOI: 10.1093/lifemeta/load014). (news-medical.net)
  • Finally, by analyzing the lipidome of skeletal muscle in weight-loss mice, the authors found that weight loss accelerated the remodeling of mitochondrial cardiolipin (CL) acyl-chains to increase tetralinoleoyl CL (TLCL) content, a species of lipids thought to be functionally critical for the respiratory enzymes. (news-medical.net)
  • Altogether, the evidence suggests that weight loss leads to an increase in skeletal muscle mitochondrial energy production efficiency, thereby reducing energy expenditure throughout the body. (news-medical.net)
  • 2023). Weight loss increases skeletal muscle mitochondrial energy efficiency in obese mice. (news-medical.net)
  • Children differ significantly from adults with respect to skeletal anatomy and physiology. (medscape.com)
  • We evaluated the maturity achieved by a predictive equation of skeletal age, physical capabilities (explosive power of upper and lower limbs, velocity of upper limbs and agility) and hormonal markers (testosterone and oestradiol) via chemiluminescence. (bvsalud.org)
  • An interdisciplinary team of researchers at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at UCLA has developed a first-of-its-kind roadmap of how human skeletal muscle develops, including the formation of muscle stem cells. (scienceblog.com)
  • Researchers in Pyle's lab and others around the world already have the capacity to generate skeletal muscle cells from human pluripotent stem cells - cells that have the ability to self-renew and to develop into any cell type in the body. (scienceblog.com)
  • So we set out to generate this map as a reference that our lab and others can use to compare the genetic signatures of the cells we are creating to those of real human skeletal muscle tissue. (scienceblog.com)
  • To create this resource, the group gathered highly specific data about two different groups of skeletal muscle cells: those from the human body, ranging from the fifth week of embryonic development to middle age, and those derived from human pluripotent stem cells the researchers generated in the lab. (scienceblog.com)
  • The group obtained 21 samples of human skeletal muscle tissue from their UCLA collaborators and from colleagues at the University of Southern California and the University of Tübingen in Germany. (scienceblog.com)
  • In addition to pinning down the true maturity of the lab-produced cells, this analysis also provided details about the other cell types present in skeletal muscle tissue across development and in populations derived from human pluripotent stem cells. (scienceblog.com)
  • The study of the human skeletal system is basic to the disciplines of biological anthropology and human biology. (kent.ac.uk)
  • Evaluation of new research in the field of human skeletal biology. (kent.ac.uk)
  • The human muscle progenitor cell or hMPC is responsible for skeletal muscle regeneration. (ibtimes.com)
  • We previously showed that bioprinted human skeletal muscle constructs were able to form multi-layered bundles with aligned myofibers. (nature.com)
  • These results suggest that the 3D bioprinted human neural-skeletal muscle constructs can be rapidly integrated with the host neural network, resulting in accelerated muscle function restoration. (nature.com)
  • We also demonstrated the feasibility of using these 3D bioprinted human skeletal muscle constructs to treat critical-sized muscle defect injuries with structural and functional restoration in a rodent model 2 . (nature.com)
  • For this particular video, students will focus on the functions of the human skeletal system. (dcmp.org)
  • Different approaches to the estimation of age at death in mature human skeletal remains were evaluated utilizing samples from 19 recent French autopsy individuals of known age at death. (astm.org)
  • The Baumann Laboratory largely focuses on elucidating the neuromuscular mechanisms of skeletal muscle weakness caused by aging and muscle myopathies. (ohio.edu)
  • To explore potential mechanisms, we employed the transgenic TG(mRen2)27 (Ren-2) hypertensive rat, which harbors the mouse renin transgene and exhibits elevated tissue ANG II levels, and skeletal muscle cell culture. (biosyn.com)
  • where the court reminded everyone that when "a party fails to develop an argument in support of his or her contention or merely constructs a skeletal argument, the issue is waived. (workerscompensation.com)
  • Just missing Halloween, NEW SKELETAL FACES play gothic post-punk crust, with dissonant sub-aquatic bass lines and discordant contemporary blackened metal riffing. (maximumrocknroll.com)
  • The skeletal anatomy of children and toddlers (see the images below) differs from the skeletal anatomy of adults . (medscape.com)
  • Overall, the Baumann Laboratory seeks to improve functionality and health span in frail and myopathic skeletal muscle through diagnosis, treatment, and prevention efforts. (ohio.edu)
  • Given the patient's history of well-water and instant-tea consumption, radiographic findings, and increased plasma fluoride [7 umol/L], the diagnosis of skeletal fluorosis was given. (fluoridealert.org)
  • An examination of all major skeletal structures and the morphological features associated with them. (kent.ac.uk)
  • Central to this work is to determine why skeletal muscle from these specific populations may be less stress resistant, resilient, and adaptable. (ohio.edu)
  • Exposure to an anthropological approach to the study of the skeletal structure of humans. (kent.ac.uk)
  • Currently, research on dietary interventions to support skeletal muscle regeneration in humans is limited. (ibtimes.com)
  • Using this definition, we for instance estimated that a typical 70 year old man who had sustained a fracture had a skeletal age of 75 years. (prohealth.com)
  • But when the man had a second fracture his skeletal age rose to 87 years. (prohealth.com)
  • These approaches have achieved bioengineered skeletal muscle tissue fabrication with cellular alignment in vitro, and some showed a degree of therapeutic potential in vivo. (nature.com)
  • Skeletal Dance Party is out now on Steam and Itch (which provides a Steam key anyway) for £5.57/€6.65/$8.09, with a demo on the Itch store page. (rockpapershotgun.com)
  • Your skeletal system functions as a structural lattice that the rest of your body is built around and depends on for support. (webmd.com)
  • A bioengineered skeletal muscle construct that mimics structural and functional characteristics of native skeletal muscle is a promising therapeutic option to treat extensive muscle defect injuries. (nature.com)
  • As a result, tea drinkers with skeletal fluorosis can go many years before they are correctly diagnosed. (fluoridealert.org)
  • Bones are a key part of your skeletal system. (webmd.com)
  • What Is Your Skeletal System? (webmd.com)
  • There are many different conditions that can impact your skeletal system, and your bones in particular. (webmd.com)
  • There are certain cancers that can form inside of your bones and impact your skeletal system. (webmd.com)
  • The skeletal system gives our body the basic form through which we can locomote through space, act on the environment, and sculpt and create the energy forms in space that we call movement. (bodymindcentering.com)
  • Through embodying the skeletal system, the mind becomes structurally organized, providing the supporting ground for our thoughts, the leverage for our ideas, and the fulcrums or spaces between our ideas for the articulation and understanding of their relationships. (bodymindcentering.com)
  • the females in the normal maturational state had higher skeletal age, body weight, body height, explosive upper limb strength and oestradiol levels. (bvsalud.org)
  • For example, the Effect of Statins on Skeletal Muscle Function and Performance (STOMP) trial is, to our knowledge, the only randomized, double-blind clinical trial that has examined aerobic exercise performance and muscle strength before and after treatmentwith placebo or high-dose atorvastatin. (medscape.com)
  • New Iberia Police actively investigating skeletal remains found on Cherokee St. (klfy.com)
  • BIRMINGHAM, Ala. ( WIAT ) - Police are working to identify a skeletal remains that were found in a backyard in Birmingham Tuesday. (wrbl.com)
  • New Iberia Police Chief Todd D'Albor confirmed that officers found skeletal remains near Cherokee Street. (klfy.com)
  • IBERIA PARISH, La. ( KLFY ) - New Iberia Police are currently on the scene where skeletal remains were found near Cherokee St. (klfy.com)
  • A diet with blueberries might improve muscle growth and repair, finds a new study which revealed that the low-calorie dark blue colored berries might improve one's potential for preservation and recovery of skeletal muscle mass. (ibtimes.com)
  • In this study, we investigate the effects of neural cell integration into the bioprinted skeletal muscle construct to accelerate functional muscle regeneration in vivo. (nature.com)
  • Here we present a study aimed at evaluating if a correlation exists between the treatment with GPAs and alterations in the two-dimensional electrophoresis (2DE) protein pattern obtained from the biceps brachii skeletal muscle from mixed-bred cattle. (lu.se)
  • This Special Issue aims to present current state-of-the-art and recent advances in skeletal muscle research in the USA. (mdpi.com)
  • Neural input into this bioprinted skeletal muscle construct shows the improvement of myofiber formation, long-term survival, and neuromuscular junction formation in vitro. (nature.com)
  • CONCLUSION: Our patient shows that [skeletal fluorosis] can result from chronic consumption of large volumes of brewed tea. (fluoridealert.org)
  • Built on the charmingly wobbly foundations of the freeware Skeletal Dance Simulator (which you can find on Itch here ), Skeletal Dance Party is vaguely Pikmin-esque, but intentionally messier. (rockpapershotgun.com)
  • All applicants must have at least 5 years post graduate out-patient/musculo-skeletal experience. (csp.org.uk)