These tumors are usually more than 5 cm in their greatest dimension, but a uterine mass of any size that has features different from the usual whorled, white, cut surface of a leiomyoma should be sampled. (medscape.com)
There were 49 cases of smooth muscle tumors: 27 leiomyomas and 22 leiomyosarcomas. (bvsalud.org)
These tumors represented 0,092% of all oral lesions, with similar distribution between genders. (bvsalud.org)
Nine thousand seven hundred and seventy histopathologic exams were accomplished during this period and only 64 (0,092%) were diagnosed as smooth muscle tumors, that corresponded to 49 cases, being 27 (55%) leiomyomas e 22 (45%) leiomyossarcomas. (bvsalud.org)
It is thought that leiomyoma is the result of either transformation of normal uterine muscle cells into abnormal cells through somatic mutations , or through the growth of abnormal uterine muscle cells into tumors. (wikidoc.org)
Carcinoma1
In the differential diagnosis of UTROSCT, we considered ESTSCLE, low-grade endometrial stromal sarcoma, epithelioid leiomyoma, and endometrioid carcinoma with sex-cord-like elements. (turkjpath.org)
Benign2
they range from benign leiomyomas to low-grade and high-grade leiomyosarcomas . (medscape.com)
The pathogenesis of leiomyoma is characterized by benign smooth muscle neoplasm . (wikidoc.org)
Myometrial1
The leiomyoma/myometrial interface is smooth and very well circumscribed (see the image below). (medscape.com)
Leiomyosarcomas2
Leiomyomas and leiomyosarcomas are believed to develop independently and are not progressive. (medscape.com)
In appearance, leiomyosarcomas of the uterus have features that range from those similar to leiomyoma (rare) to overtly malignant, gross features similar to those of high-grade sarcomas that may occur anywhere in the body, with infiltrative edges, necrosis, hemorrhage, and a variegated cut surface. (medscape.com)
Pelvic1
Microscopic examination of the pelvic mass showed a biphasic tumor composed of epithelial and mesenchymal components, suggestive of synovial sarcoma. (ochsnerjournal.org)
The histologic distinction between atypical leiomyoma and low grade leiomyosarcoma is difficult and is based on the following criteria: number of mitosis, cellular atypia and pattern of necrosis 5,6 . (bvsalud.org)
Characteristic2
On gross pathology , round, well circumscribed, non-encapsulated, solid white or tan nodules , and whorled are characteristic findings of leiomyoma. (wikidoc.org)
On microscopic histopathological analysis, elongated and spindle-shaped cells with a cigar-shaped nucleus are characteristic findings of leiomyoma. (wikidoc.org)
Frequent2
Leiomyomas are more frequent in Black women. (medscape.com)
Leiomyoma was more frequent in the fifth decade of life. (bvsalud.org)
Clinical Features2
The aim of this study is to analyse and compare the clinical features of leiomyoma and leiomyosarcoma, because they help in the differential diagnosis. (bvsalud.org)
The aim of this retrospective study is to evaluate and compare clinical features, like gender, age, location and symptomatology of leiomyoma and leiomyosarcoma, and review the literature from 1970 to 2010, since there isn't any recent comparative article. (bvsalud.org)
Pregnancy1
Uterine leiomyoma must be differentiated from other diseases that cause uterine mass, such as: uterine adenomyoma , pregnancy , hematometra , uterine sarcoma , uterine carcinosarcoma, and metastasis . (wikidoc.org)
Oral2
Records of oral leiomyoma and leiomyosarcoma from Oral Pathology Department of Dental School at University of São Paulo during the period 1962-2010 were analysed. (bvsalud.org)
The mainstay of therapy for uterine leiomyoma is oral contraceptive pills , either combination pills or progestin-only , Gonadotropin-releasing hormone analogs . (wikidoc.org)
Found3
Most leiomyomas are found incidentally. (medscape.com)
From 27 leiomyomas, 21 (78%) were vascular type and only 6 (22%) were solid, no epithelioid was found. (bvsalud.org)
Microscopic evaluation showed anastomosing cords, trabeculae, nests, and tubules of epithelial-like cells found in a fibroblastic stroma (Figure 1 ). (turkjpath.org)
Include1
Common risk factors in the development of uterine leiomyoma include African-American race, early menarche , prenatal exposure to diethylstilbestrol , having one or more pregnancies extending beyond 20 weeks, obesity , significant consumption of beef and other red meats, hypertension , family history , and alcohol consumption. (wikidoc.org)
Years1
Leiomyoma is more commonly observed among patients aged 40 years and older. (wikidoc.org)
Smooth muscle1
Nine thousand seven hundred and seventy histopathologic exams were accomplished during this period and only 64 (0,092%) were diagnosed as smooth muscle tumors, that corresponded to 49 cases, being 27 (55%) leiomyomas e 22 (45%) leiomyossarcomas. (bvsalud.org)