Similar angiotensin converting enzyme inhibitors. Medical search. Frequent questions

For management of heart failure with reduced ejection fraction (HFrEF), medication classes consist of diuretics, angiotensin-receptor blockers (ARBs), angiotensin-converting enzyme (ACE) inhibitors, and beta-blockers. (medscape.com)
Objective To determine the effect of combinations of statins, aspirin, β blockers, and angiotensin converting enzyme inhibitors in the secondary prevention of all cause mortality in patients with ischaemic heart disease. (bmj.com)
Exposure was current use of different combinations of statins, aspirin, β blockers, and angiotensin converting enzyme inhibitors before death in cases, or the equivalent date in controls. (bmj.com)
Treatments associated with the smallest reduction in all cause mortality were β blockers alone (19% reduction, 37% reduction to 4% increase), angiotensin converting enzyme inhibitors alone (20% reduction, 1% to 35%), and combined statins and angiotensin converting enzyme inhibitors (31% reduction, 57% reduction to 12% increase). (bmj.com)
Conclusions Combinations of statins, aspirins, and β blockers improve survival in high risk patients with cardiovascular disease, although the addition of an angiotensin converting enzyme inhibitor conferred no additional benefit despite the analysis being adjusted for congestive cardiac failure. (bmj.com)
1 - 5 Although combinations of drugs (as proposed in the Polypill) 6 have been received with enthusiasm, we found no direct evidence evaluating the effects of statins, aspirin, β blockers, and angiotensin converting enzyme inhibitors in combination. (bmj.com)
Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers for treating essential hypertension. (qxmd.com)
The relative effectiveness of angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) for lowering blood pressure is unknown. (qxmd.com)
Based on initial reports from China, and subsequent evidence that arterial hypertension may be associated with increased risk of mortality in hospitalized COVID-19 infected subjects, hypotheses have been put forward to suggest a potential adverse effects of angiotensin converting enzyme inhibitors (ACE-i) or Angiotensin Receptor Blockers (ARBs). (escardio.org)
The general approach to therapy of ischemic nephropathy involves control of hypertension, preferably with angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs). (medscape.com)
With the capability of inducing elevated expression of ACE2, the cellular receptor for SARS-CoV-2, angiotensin II receptor blockers or angiotensin-converting enzyme inhibitors (ARBs/ACEIs) treatment may have a controversial role in both facilitating virus infection and reducing pathogenic inflammation. (medrxiv.org)
Comparative First-Line Effectiveness and Safety of ACE (Angiotensin-Converting Enzyme) Inhibitors and Angiotensin Receptor Blockers. (pace-cme.org)
Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are equally recommended as first-line therapy for the treatment of hypertension in the 2017 ACC/AHA and 2018 ESC/ESH guidelines. (pace-cme.org)
Angiotensin converting enzyme (ACE) inhibitors versus angiotensin receptor blockers for primary hypertension. (pace-cme.org)
CORD: COmparison of Recommended Doses of ace inhibitors and angiotensin II receptor blockers Int J Cardiol. (pace-cme.org)
Valsartan belongs to a class of medicine generally known as angiotensin II receptor blockers (ARBs). (dietbab.com)
Studies of beta-blockers, angiotensin-converting enzyme inhibitors, and angiotensin II receptor blockers have been unsuccessful in this group of patients. (the-hospitalist.org)
Calcium channel blockers ( CCBs ) and angiotensin-converting enzyme (ACE) inhibitors are used to treat high blood pressure . (medicinenet.com)
Side effects of calcium channel blockers and ACE inhibitors that are similar include rash , low blood pressure , drowsiness, and dizziness . (medicinenet.com)
Side effects of calcium channel blockers that are different from ACE inhibitors include constipation , nausea , headache , swelling of the legs and feet with fluid ( edema ), liver dysfunction, overgrowth of the gums, and sexual dysfunction. (medicinenet.com)
Side effects of ACE inhibitors that are different from calcium channel blockers include cough , elevated blood potassium levels, headache , weakness , abnormal taste (metallic or salty), chest pain , increased uric acid levels, sun sensitivity, and increased BUN and creatinine levels. (medicinenet.com)
What are the side effects of calcium channel blockers and ACE inhibitors? (medicinenet.com)
Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are often used. (medlineplus.gov)
There is "little, if any, clinical reason" to use angiotensin-converting enzyme (ACE) inhibitors for the treatment of hypertension or other cardiovascular indications because angiotensin receptor blockers (ARBs) are just as effective with fewer side effects, a new review concludes. (medscape.com)

Therefore, current recommendations are that ACE inhibitors and ARBs are appropriate for African Americans, but not as monotherapy. (cvpharmacology.com)
To compare the benefits and harms of ACE inhibitors versus ARBs for treating essential hypertension in adults. (qxmd.com)
61 clinical studies that directly compared ACE inhibitors versus ARBs in adult patients with essential hypertension, reported an outcome of interest, lasted at least 12 weeks, and included at least 20 patients. (qxmd.com)
There were fewer withdrawals due to adverse events and greater persistence with therapy for ARBs than for ACE inhibitors, although this evidence was not definitive. (qxmd.com)
Patient subgroups for whom ACE inhibitors or ARBs were more effective, associated with fewer adverse events, or better tolerated were not identified. (qxmd.com)
Available evidence shows that ACE inhibitors and ARBs have similar effects on blood pressure control, and that ACE inhibitors have higher rates of cough than ARBs. (qxmd.com)
The concern arises from the observation that, similar to the coronavirus causing SARS, the COVID-19 virus binds to a specific enzyme called ACE2 to infect cells, and ACE2 levels are increased following treatment with ACE-i and ARBs. (escardio.org)
A study by Bianchi et al suggested that statins, in addition to ACE inhibitors and ARBs, may reduce proteinuria and slow the progression of kidney disease. (medscape.com)
Many angiotensin-converting enzyme (ACE) inhibitors, in particular, and some ARBs also have a half-life much less than 24 h, and depending on the dose, the BP-lowering effect may not last for 24 h. (lww.com)
Messerli and colleagues reviewed data from 119 randomized clinical trials of ACE inhibitors and ARBs in more than half a million patients and found no difference in efficacy between the two drug classes with regard to the surrogate endpoint of blood pressure and the outcomes of all-cause mortality, cardiovascular mortality, myocardial infarction , heart failure , stroke , and end-stage renal disease. (medscape.com)
Despite this, most guidelines for the management of patients with cardiovascular disease recommend ACE inhibitor s as first-choice therapy, whereas ARBs are merely considered an alternative for ACE inhibitor-intolerant patients, Messerli and colleagues point out. (medscape.com)
Because efficacy is similar but adverse events are fewer with ARBs, comprehensive risk-to-benefit analysis indicates that clinicians no longer have any valid reason to prescribe ACE inhibitors for the treatment of hypertension and its compelling indications. (medscape.com)
The original trials in coronary heart disease (CHD) were done with ACE inhibitors, and these trials were larger and the placebo event rates were higher than the later trials with ARBs, so it was easier to show convincing benefits. (medscape.com)
Dr Messerli and colleagues have conducted a very thorough review of the clinical trials and they are right that, by and large, there is no evidence that ACE inhibitors are more effective at reducing blood pressure or cardiovascular outcomes, and ARBs have fewer side effects," said hypertension expert Michael Weber, MD, SUNY Downstate College of Medicine, New York City. (medscape.com)
ACE inhibitors are older and have decade more data than ARBs. (medscape.com)
ACE inhibitors have a 20% cough incidence, closer to 50% in the Asian populations, ARBs don't. (medscape.com)
In short, I do prefer ARBs to ACE inhibitors for most people, but primarily because ARBs have a greater blood pressure-lowering effect than ACE inhibitors - at least this was the case for azilsartan . (medscape.com)
Heart failure expert John McMurray, MD, University of Glasgow, United Kingdom, noted that ACE inhibitors were tested in clinical trials in heart failure before ARBs were available and were shown to reduce mortality. (medscape.com)

Medications known to be unsafe in pregnancy, such as angiotensin-converting enzyme inhibitors and statins, should be discontinued. (nih.gov)
Limitations of the study include residual confounding from comorbidities not accounted for in the matching method, lack of consideration for the effects of cardiovascular prescription drugs like angiotensin-converting enzyme inhibitors or statins, and possible underestimation of adverse cardiovascular risk given the relatively healthy UK Biobank cohort, the study authors noted. (medscape.com)

Phosphodiesterase-5 (PDE-5) inhibitors cause smooth muscle relaxation and antiproliferative effects in the vasculature, leading to a reduction in pulmonary artery pressure in patients with WHO group 1 pulmonary hypertension. (medscape.com)
ACE inhibitors are considered 'first-line therapy' in the treatment of stage 1 hypertension . (cvpharmacology.com)
after multivariable adjustment, mortality was similar without evidence of a differential association between hypertension and mortality according to sex. (duke.edu)
CONCLUSION: Hypertension is more prevalent in women than in men with ACS, and its medical management varies by sex, but its association with mortality is similar. (duke.edu)
Vasotec (enalapril maleate) is an ACE ( angiotensin converting enzyme ) inhibitor used to treat high blood pressure ( hypertension ), congestive heart failure , kidney problems caused by diabetes , and to improve survival after a heart attack . (rxlist.com)
The beneficial effects of enalapril in hypertension and heart failure appear to result primarily from suppression of the renin-angiotensin-aldosterone system. (nih.gov)
While the mechanism through which enalapril lowers blood pressure is believed to be primarily suppression of the renin-angiotensin- aldosterone system, enalapril is antihypertensive even in patients with low-renin hypertension. (nih.gov)
Useful for hypertension and heart failure in patients who are intolerant of ACE inhibitors. (medscape.com)
Relative risk reduction from blood pressure reduction is similar across populations with varying absolute risk, so the absolute benefit is greater in patients who are at higher risk independent of their hypertension (for example, patients with diabetes or hyperlipidemia), and such patients would be expected to benefit from more aggressive treatment to a lower blood pressure goal. (globalrph.com)
Acupuncture was found effective for reducing hypertension and acupuncture outperformed Capoten, an ACE (angiotensin-converting enzyme) inhibitor medication used for the regulation of hypertension. (healthcmi.com)
ACE inhibitors are also used to treat left ventricular dysfunction and heart failure , to prevent strokes , and to prevent and treat kidney disease in people with hypertension or diabetes . (medicinenet.com)
In hypertension, it is used as an adjunct to prolonged therapy with thiazides and similar agents to prevent potassium depletion. (janusinfo.se)

VASOTEC® (Enalapril Maleate) is the maleate salt of enalapril, the ethyl ester of a long-acting angiotensin -converting enzyme inhibitor, enalaprilat. (rxlist.com)
Enalapril, after hydrolysis to enalaprilat, inhibits angiotensin-converting enzyme (ACE) in human subjects and animals. (nih.gov)
The response to these doses of enalapril, 4 h after administration, is similar, but only 20 and 40 mg have an effect that endures for 24 h. (lww.com)

Therefore, ACE inhibitors may act at these sites besides blocking the conversion of angiotensin in the circulating plasma. (cvpharmacology.com)
ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. (nih.gov)
Prevents conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, resulting in lower aldosterone secretion. (medscape.com)

Angiotensin-converting enzyme inhibitors dose optimizations (ACEIs) are essential to boost the treatment outcome in heart failure patients (HF) with reduced ejection fraction. (dovepress.com)

There appeared to be significant effect modification for the primary endpoint by MI location (p = 0.03), angiotensin-converting enzyme inhibitor/angiotensin-receptor blocker at baseline (p = 0.04), and diabetes (p = 0.02). (acc.org)
For patients with newly diagnosed Stage C heart failure with reduced ejection fraction (HFrEF), a beta-blocker and an angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB)/angiotensin receptor-neprilysin inhibitor (ARNI) should be started in any order. (acc.org)
A retrospective cohort study was conducted to evaluate the independent and interactive effects of pulse pressure and antihypertensive class (specifically angiotensin converting enzyme inhibitor/angiotensin type 1 receptor blocker, or beta blocker) on mortality following acute ischemic stroke. (scirp.org)
Angiotensin converting enzyme inhibitor/angiotensin type 1 receptor blocker based therapy was associated with lower follow-up mortality when beta blocker was not used in pulse pressure (scirp.org)
Prospective analysis will be needed to confirm the protective effect of angiotensin converting enzyme inhibitor/angiotensin type 1 receptor blocker based on pulse pressure in acute ischemic stroke. (scirp.org)
Phenotypic spectrum and antialbuminuric response to angiotensin converting enzyme inhibitor and angiotensin receptor blocker therapy in pediatric Dent disease. (cdc.gov)

In using VASOTEC consideration should be given to the fact that another angiotensin converting enzyme inhibitor, captopril, has caused agranulocytosis, particularly in patients with renal impairment or collagen vascular disease, and that available data are insufficient to show that VASOTEC does not have a similar risk (see WARNINGS ). (rxlist.com)
Similar precautions to captopril with respect to potential increase in potassium and creatinine. (medscape.com)
4 Ever since the introduction of the 1st ACE-i, captopril in , ACE inhibitor have become the cornerstone in the treatment of heart failure and left ventricular dysfunction. (slideplayer.com)

They had the importance of definition of sodium intake with other medications, such as angiotensin-converting enzyme. (kedirikota.go.id)

7 Overview of Randomized Trials of Angiotensin-Converting Enzyme Inhibitors on Mortality and Morbidity in Patients With Heart Failure Objective -To evaluate the effect of ACE inhibitors on mortality and morbidity in patients with symptomatic congestive heart failure. (slideplayer.com)

The increase in bradykinin is also believed to be responsible for a troublesome side effect of ACE inhibitors, a dry cough. (cvpharmacology.com)
Consistent fair- to good-quality evidence showed that ACE inhibitors were associated with a greater risk for cough. (qxmd.com)
May induce a more complete inhibition of the renin-angiotensin system than ACE inhibitors, does not affect the response to bradykinin, and is less likely to be associated with cough and angioedema. (medscape.com)
But ACE inhibitors have a higher incidence of adverse reactions - namely cough and very low risks of angioedema and fatalities - that are more prevalent in dark-skinned people, they write. (medscape.com)
Some may think the ACE inhibitor cough is just a nuisance, but it can cause patients to keep coming back to the doctor or stop taking the drug altogether," he noted. (medscape.com)
This is particularly relevant in Asia where cough with ACE inhibitors occurs more frequently, and in Africa, as angioedema is more common in blacks. (medscape.com)

Angiotensin II stimulates the adrenal cortex to release aldosterone , which acts on the kidneys to increase sodium and water reabsorption, leading to increased blood volume and arterial pressure. (cvpharmacology.com)
Promote renal excretion of sodium and water ( natriuretic and diuretic effects) by blocking the effects of angiotensin II in the kidney, blocking angiotensin II stimulation of aldosterone secretion, and by blocking angiotensin II stimulated ADH release. (cvpharmacology.com)
there is an increased risk of severe hypotension and renal insufficiency when patients with bilateral renal artery stenosis or stenosis of the artery to a single functioning kidney are treated with medicinal products that affect the renin-angiotensin-aldosterone system. (medicines.org.uk)
Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. (nih.gov)
Inhibition of ACE results in decreased plasma angiotensin II, which leads to decreased vasopressor activity and to decreased aldosterone secretion. (nih.gov)
Nonpeptide angiotensin II receptor antagonist that blocks the vasoconstricting and aldosterone-secreting effects of angiotensin II. (medscape.com)
After initiation of beta-blocker and angiotensin antagonist, addition of an aldosterone antagonist should be considered with close monitoring of electrolytes. (acc.org)

Among angiotensin antagonists, ARNIs are preferred agents. (acc.org)

Angiotensin II also facilitates the release of norepinephrine from sympathetic adrenergic nerves and inhibits norepinephrine reuptake by these nerves. (cvpharmacology.com)

This vasoconstrictor is formed by the proteolytic action of renin (released by the kidneys) acting on circulating angiotensinogen to form angiotensin I. Angiotensin I is then converted to angiotensin II by angiotensin converting enzyme (ACE). (cvpharmacology.com)

Elevated plasma renin is not required for the actions of ACE inhibitors, although ACE inhibitors are more efficacious when circulating levels of renin are elevated. (cvpharmacology.com)
We know that the renin-angiotensin system is found in many tissues, including heart, brain, vascular and renal tissues. (cvpharmacology.com)
They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. (curehunter.com)
Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus. (rxlist.com)
Removal of angiotensin II negative feedback on renin secretion leads to increased plasma renin activity. (nih.gov)
[1] is an important contribution to the question when should drugs that act on the renin-angiotensin system (RAS) be administered. (lww.com)
Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. (medscape.com)

following oral administration, it is bioactivated by hydrolysis of the ethyl ester to enalaprilat, which is the active angiotensin-converting enzyme inhibitor. (rxlist.com)

Owing to survival benefit in patients with left ventricular systolic dysfunction, patients should be initiated on an ACE inhibitor or, if unable to tolerate, an ARB. (medscape.com)

For patients unable to tolerate ACE inhibitors. (medscape.com)

This observation may be due to higher doses of angiotensin-converting enzyme inhibitors and/or closer follow-up. (duke.edu)

The researchers discovered that acupuncture was more effective than the ACE inhibitor medication for these pateints. (healthcmi.com)

Effects of different angiotensin-converting enzyme (ACE) inhibitors on ischemic isolated rat hearts: relationship between cardiac ACE inhibition and cardioprotection. (aspetjournals.org)

Other endpoints including mortality (10.4% vs. 10.7%, p = 0.64), MI (6.2% vs. 7.7%, p = 0.17), stroke (1.2% vs. 1.5%, p = 0.53), and angina hospitalization (1.5% vs. 2.1%, p = 0.36) were similar between the two arms. (acc.org)
Individual endpoints including mortality (10% vs. 11%, p = 0.61), MI (7% vs. 7%, p = 0.79), stroke (1% vs. 2%, p = 0.14), coronary revascularization (15% vs. 18%, p = 0.13), and angina hospitalization (1% vs. 2%, p = 0.36) were similar between the two arms. (acc.org)
In the nondiabetic patients who did not receive an ACE inhibitor, mortality was about 60% - worse than most cancers," Dr. Kearney said. (the-hospitalist.org)
So, if you get patients on an optimal dose of an ACE inhibitor, you improve their mortality substantially, whether they have diabetes or not. (the-hospitalist.org)
8 conclusion: these trials have established the role of ACE inhibitors in reducing mortality and heart failure hospitalization in patients who have heart failure. (slideplayer.com)
17 CONCLUSION- Overall mortality was similar in the two groups. (slideplayer.com)

And the side effect of angioedema, although rare, can be fatal, and if ACE inhibitors are proposed as part of the polypill then millions will be exposed and fatalities will occur. (medscape.com)

he added: "Ever since the superb HOPE trial in 2000, ACE inhibitors have become a sacred cow. (medscape.com)

In patients with PH-LHD, use of PDE-5 inhibitors has shown mixed results. (medscape.com)
Patients with MVA can experience chest pains similar to those of a heart attack and/or shortness of breath, which can lead to them being admitted to hospital. (escardio.org)
Currently, the National Institute [for] Health and Care Excellence recommends prophylactic low molecular weight heparin for VTE prevention in hospitalized patients with COVID-19 and in patients who would otherwise be admitted to hospital (eg, hospital at home) for a minimum of 7 days," the authors note, consistent with similar recommendations from the British Thoracic Society and the American Society of Hematology. (medscape.com)
In patients with diabetes, there was a similar pattern. (the-hospitalist.org)
Sodium-glucose cotransporter-2 (SGLT-2) inhibitors should also be considered for HFrEF with New York Heart Association (NYHA) class II-IV patients. (acc.org)
Cancer patients may adopt a similar mentality after caring for and connecting with them. (wakeup-world.com)
Nevertheless, they are not free of side effects, and some patients should not use ACE inhibitors. (medicinenet.com)
Les dossiers de 622 patients âgés en moyenne de 58,3 ans (écart type 12,9) ont été étudiés. (who.int)
Des stratégies préventives doivent être mises en oeuvre afin d'améliorer le pronostic à long terme des patients libyens et de réduire la morbidité et la mortalité globales dues à la coronaropathie. (who.int)
Chez les patients hypertendus, le taux de mortalité était plus élevé uniquement chez les patients admis pour un infarctus du myocarde avec sus-décalage du segment ST. Après ajustement des résultats en fonction des variables de référence, l'hypertension s'est révélé être un facteur prédictif indépendant de l'insuffisance cardiaque (OR = 1,31) et de l'accident vasculaire cérébral (OR = 2,47). (who.int)

Therefore, ACE inhibitors, by blocking the breakdown of bradykinin, increase bradykinin levels, which can contribute to the vasodilator action of ACE inhibitors. (cvpharmacology.com)
Dilate arteries and veins by blocking angiotensin II formation and inhibiting bradykinin metabolism. (cvpharmacology.com)
ACE is identical to kininase, an enzyme that degrades bradykinin. (nih.gov)

The beta-blocker component of the trial yielded similar results. (the-hospitalist.org)
The message here is, if you have a patient with ejection fraction heart failure and diabetes, get them on the optimal dose of a beta-blocker, even at the expense of an ACE inhibitor. (the-hospitalist.org)

Women with diabetes have increased risk for adverse maternal and neonatal outcomes, and similar risks are present with type 1 and type 2 diabetes. (nih.gov)
Both forms of diabetes require similar intensity of diabetes care. (nih.gov)

A diuretic or calcium-channel blocker should be used with an ACE inhibitor or ARB to achieve the target reduction in blood pressure in these patient populations. (cvpharmacology.com)
ZESTORETIC® (Lisinopril and Hydrochlorothiazide) combines an angiotensin converting enzyme inhibitor, lisinopril, and a diuretic, hydrochlorothiazide. (globalrph.com)

Adverse events were mostly similar, although hypocalcemia (6.2% vs. 3.5%, p = 0.008) was higher in the chelation therapy arm. (acc.org)

By reducing the effects of angiotensin II on the kidney, ACE inhibitors cause natriuresis and diuresis , which decreases blood volume and cardiac output, lowering arterial pressure. (cvpharmacology.com)
Angiotensin converting enzyme inhibitors (ACE inhibitors) slow (inhibit) the activity of the enzyme ACE, which decreases the production of angiotensin II. (medicinenet.com)

Lisinopril, a synthetic peptide derivative, is an oral long-acting angiotensin converting enzyme inhibitor. (globalrph.com)

Down regulate sympathetic adrenergic activity by blocking the facilitating effects of angiotensin II on sympathetic nerve release and reuptake of norepinephrine. (cvpharmacology.com)

ACE2 is an enzyme that's critical for maintaining blood pressure. (healthandwealthbulletin.com)
ACE inhibitors make the heart increase how much ACE2 it has. (healthandwealthbulletin.com)

Taking angiotensin-converting enzyme (ACE) inhibitors or non-steroidal anti-inflammatory drugs (NSAIDs) . (medicalnewstoday.com)

Further symptom reduction can be achieved by providing additional nutrients for the lungs such as bromelain (pineapple enzyme), which reduces allergy symptoms, enhances circulation, removes clots and other obstructions of the circulation system, digests protein and oils so they are better assimilated by the body, and fights parasites. (electroherbalism.com)
[2,3] Their study [1] clearly shows that when an angiotensin-receptor blocking (ARB) drug is administered in a dose that has a full 24-h duration of effect (valsartan 320 mg), the time of administration has little influence on the 24 h, day or sleep BP reduction. (lww.com)

This action of angiotensin II augments sympathetic activity on the heart and blood vessels, promoting cardiac stimulation and vasoconstriction. (cvpharmacology.com)
Additionally, individuals with Takotsubo cardiomyopathy typically have similar symptoms to a heart attack. (medicalnewstoday.com)
Here, there is also an increase in troponin levels, though a heart attack will also produce similar results. (medicalnewstoday.com)

Angiotensin II constricts arteries and veins by binding to AT 1 receptors on the smooth muscle, which are coupled to a Gq-protein and the IP 3 signal transduction pathway . (cvpharmacology.com)
Individuals with bilateral renal artery stenosis (narrowing of the arteries that supply the kidneys) may experience worsening of kidney function, and people who have had a severe reaction to ACE inhibitors probably should avoid them. (medicinenet.com)

Over the years, theoreticians and empiricists working in a wide range of disciplines, including physiology, ethology, psychology, and behavioral ecology, have suggested a variety of reasons why individual differences in behavior might change over time, such that different individuals become more similar (convergence) or less similar (divergence) to one another. (researchgate.net)

However, there were similar falls in 24-h ambulatory blood pressure and night-time (sleep) BP. (lww.com)
Both conditions share similar risk factors, such as obesity and high blood pressure. (telehealthpharmacy.ie)
Researchers discovered dogs could lower one's blood pressure more effectively than an angiotensin-converting enzyme (ACE) inhibitor. (wakeup-world.com)

Baseline characteristics were fairly similar between the two arms. (acc.org)
RESULTS: Baseline characteristics were similar except for slightly higher age in the intervention group. (duke.edu)

Anatomy29

Organisms11

Diseases32

Chemicals and Drugs121

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Psychiatry and Psychology1

Phenomena and Processes32

Disciplines and Occupations1

Health Care15

Blockers24

ARBs18

Statins2

Hypertension12

Enalapril3

Conversion of angiotensin3

ACEIs1

Receptor blocker6

Captopril3

Medications1

Congestive heart f1

Cough6

Aldosterone7

Antagonists1

Inhibits1

Vasoconstrictor1

Renin7

Enalaprilat1

Left ventricular1

Unable to tolerate1

Doses1

Medication1

Ischemic1

Mortality6

Angioedema1

20001

Patients10

Bradykinin3

Beta-blocker2

Diabetes2

Diuretic2

Adverse1

Decreases2

Lisinopril1

Effects1

ACE22

NSAIDs1

Reduction2

Heart3

Arteries2

Differences1

Blood3

Characteristics2