Chemicals and Drugs
PimozidePenfluridolThioridazineMibefradilApomorphineCyproheptadineReceptors, Dopamine
OrapQuinidineAntipsychoticsThioridazineHaloperidolErythromycinMedicinesCalciumDoctorsStructurallySymptomsSerotoninEfficacyAntipsychoticDrugsEffectsAgentsHaloperidolAtypicalCONTRAINDICATIONSExtrapyramidalElimination halfChronicAcuteTrialsReactionsDoseDroperidolEvidenceMedicationsIncidenceTherapeuticOralPatientsDrugExperienceTreatmentSignificantDisease
Orap2
  • Miscellaneous conventional antipsychotic medications include haloperidol (Haldol: 1967), loxapine (Loxitane: 1976), molindone (Moban: 1974) and pimozide (Orap: 1984, used largely for Tourette syndrome). (nih.gov)
  • You or your child should not use erythromycin (Ery-Tab®), pimozide (Orap®), or quinidine (Cardioquin®) while using this medicine because of the risk of unwanted side effects. (bali-wedding-photography.com)
Quinidine1
  • Coadministration of other medicinal products known to prolong the QT interval and which are metabolised via the cytochrome P450 (CYP) 3A4 such as cisapride, astemizole, pimozide, quinidine, and erythromycin are contraindicated in patients receiving fluconazole (see sections 4.4 and 4.5). (tajgenerics.com)
Antipsychotics3
  • Related to other diphenylbutylpiperidine antipsychotics, pimozide and fluspirilene, penfluridol has an extremely long elimination half-life and its effects last for many days after single oral dose. (wikipedia.org)
  • Penfluridol is indicated for antipsychotic treatment of chronic schizophrenia and similar psychotic disorders, it is, however, like most typical antipsychotics, being increasingly replaced by the atypical antipsychotics. (wikipedia.org)
  • Antipsychotics that can be reduced by switching to a similar drug. (taperingstrip.com)
Thioridazine1
Haloperidol1
  • Its antipsychotic potency, in terms of dose needed to produce comparable effects, is similar to both haloperidol and pimozide. (wikipedia.org)
Erythromycin1
  • 1. Inform your doctor if you are allergic to azithromycin or similar medicines like erythromycin, clarithromycin, and telithromycin. (alphadrug.in)
Medicines2
  • any other similar medicines. (mydr.com.au)
  • if you are taking or have taken medicines called monoamine oxidase inhibitors ( MAOIs ) (eg selegiline , moclobemide) or medicines similar to MAOIs (eg linezolid). (zeepedia.com)
Calcium3
  • Multiple drug interaction sites have been identified for L-type calcium channels, suggesting a similar possibility exists for the structurally related T-type channels. (johnshopkins.edu)
  • Here, we radiolabel a novel amide T-type calcium channel antagonist (TTA-A1) and show that several known antagonists, including mibefradil, flunarizine, and pimozide, displace binding in a concentration-dependent manner. (johnshopkins.edu)
  • On the other hand, the calcium channel blockers pimozide, diltiazem as well as LY-83,583, a guanylate cyclase inhibitor, which were reported to block CNG channels, enhance PGE 2 binding. (bgu.ac.il)
Doctors1
  • While no one test that can tell doctors if a person has Tourette syndrome, tests like computed tomography (CT), magnetic resonance imaging (MRI), blood tests and electroencephalogram (EEG) can help doctors rule out other conditions that could have similar symptoms as TS. (marijuanadoctors.com)
Structurally1
  • The antipsychotic agents in clinical use include the phenothiazines and structurally similar compounds such as thioxanthenes, benazepines, butyrophenones, diphenylbutylpiperidines and miscellaneous similar heterocyclic compounds. (nih.gov)
Symptoms2
  • Post-traumatic stress disorder is a condition that can occur after a very emotionally traumatic experience, with some symptoms similar to depression and anxiety. (zeepedia.com)
  • Prozac withdrawal symptoms are more or less similar to the side effects listed above. (psychologenie.com)
Serotonin1
  • Serotonin is another similar neurotransmitter that's usually associated with a positive, uplifted mood. (graniterecoverycenters.com)
Efficacy1
  • no randomized clinical trials are available, however, and reported cases suggest similar efficacy. (cdc.gov)
Antipsychotic1
  • A 2006 systematic review examined the use of penfluridol for people with schizophrenia: Typical antipsychotic Diphenylbutylpiperidine Fluspirilene Pimozide Carpipramine (atypical antipsychotic) Clocapramine (atypical antipsychotic) Anvisa (2023-03-31). (wikipedia.org)
Drugs1
  • Similar in that age range have been at least six weeks out of your own creamy hummus at home for antidepressant drugs. (haywoods-trimmings.com)
Effects2
  • Again, the same as its brother-sisters Viagra and Kamagra, Levitra causes similar side effects. (mapofmedicine.com)
  • Similar effects can be used with a sampling cone, and passes through citalopram a simple answer to these findings. (cortemadera.com)
Agents1
  • In hypertension, it is used as an adjunct to prolonged therapy with thiazides and similar agents to prevent potassium depletion. (janusinfo.se)
Haloperidol5
  • Patient groups have usually been to small to allow statistically significant differences to be apparent, but in some trials pimozide was significantly superior to trifluoperzine and to haloperidol. (nih.gov)
  • Pimozide versus Haloperidol in acute schizophrenia. (nih.gov)
  • Fluphenazine is a high-potency typical antipsychotic with pharmacology similar to that of haloperidol. (medscape.com)
  • Its antipsychotic potency, in terms of dose needed to produce comparable effects, is similar to both haloperidol and pimozide. (wikipedia.org)
  • Pimozide, chlorpromazine and haloperidol had dissociation constants of 0.8, 5 and 9 p.54 respectively. (erowid.org)
Atypical1
  • Pimozide is an atypical neuroleptic approved by the US Food and Drug Administration (FDA) for treatment of tics. (medscape.com)
CONTRAINDICATIONS1
  • Effects of concomitant medication and genetic variations on pimozide metabolism are described in the CONTRAINDICATIONS and PRECAUTIONS sections. (nih.gov)
Extrapyramidal1
  • The incidence and severity of extrapyramidal reactions with pimozide are low, but suitably designed controlled studies are needed to determine whether its use leads to a reduction in the requirement for antiparkinsonian medication. (nih.gov)
Elimination half1
  • The mean serum elimination half-life of pimozide in schizophrenic patients was approximately 55 hours. (nih.gov)
Chronic1
  • Published data suggest that in chronic schizophrenia, pimozide 4 to 6mg daily is indistinguishable from maintenance doses of chlorpromazine, fluphenazine, flupenthixol, perphenazine, or thioidazine. (nih.gov)
Acute2
  • They are presynaptic depleting agents that have acute adverse effects similar to neuroleptics but theoretically may avoid the risk of tardive dyskinesia. (medscape.com)
  • Aerobic and facultative gram-positive microorganisms treatment of acute bacterial sinusitis azithromycin 12 mgkg once a eyes twice daily 8 to compared to penicillin V 250 studies in azithromycin staph infection similar pathophysiology drop in affected eyes once daily for the next 5 of acute otitis media in. (awardspace.us)
Trials1
  • no randomized clinical trials are available, however, and reported cases suggest similar efficacy. (cdc.gov)
Reactions1
  • the manufacturers have received other reports of similar reactions, even with infusions, but the incidence seems to be considerably lower than with erythromycin. (antiinfectivemeds.com)
Dose1
  • More than 50% of a dose of pimozide is absorbed after oral administration. (nih.gov)
Droperidol1
  • Pimozide & Bezitramide (& Oxiperomide & Neflumozide) are also made from 4-(1-Benzimidazolinone)piperidine precursor Droperidol is similar, but has a tetrahydropyridine ring. (wikipedia.org)
Evidence1
  • Evidence supporting approval of Pimozide Tablets, USP for use in Tourette's Disorder was obtained in two controlled clinical investigations which enrolled patients between the ages of 8 and 53 years. (nih.gov)
Medications1
  • Some scientists are hopeful because these medications have been used to treat similar viral infections. (medlineplus.gov)
Incidence1
  • In anxious patients, pimozide seems to offer no advantages over currently available anxiolytic agents, either in terms of efficacy or incidence of side-effects. (nih.gov)
Therapeutic1
  • Although the pathogenesis of HIV infection and the general virologic and immunologic principles underlying the use of antiretroviral therapy are similar for all HIV-infected persons, unique therapeutic and management considerations apply to HIV-infected children. (cdc.gov)
Oral1
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Patients4
  • There was a 13-fold interindividual difference in the area under the serum pimozide level-time curve and an equivalent degree of variation in peak serum levels among patients studied. (nih.gov)
  • Pimozide Tablets, USP is indicated for the suppression of motor and phonic tics in patients with Tourette's Disorder who have failed to respond satisfactorily to standard treatment. (nih.gov)
  • Pimozide Tablets, USP should be reserved for use in Tourette's Disorder patients whose development and/or daily life function is severely compromised by the presence of motor and phonic tics. (nih.gov)
  • Pimozide, which selectively blocks dopamine type-2 receptors, was the drug first reported to be useful in the condition, and several series indicated a good response in most patients who accepted it. (cdc.gov)
Drug1
  • Tybost has drug interactions similar to Norvir, but they are not interchangeable, and there may be some drug interactions with Tybost that are not observed with Norvir. (positivelyaware.com)
Experience1
  • Also, you may experience symptoms such as mood swings, headache , tiredness, sleep changes, and brief feelings similar to electric shock. (webmd.com)
Treatment2
  • Pimozide Tablets, USP is not intended as a treatment of first choice nor is it intended for the treatment of tics that are merely annoying or cosmetically troublesome. (nih.gov)
  • 1. Pimozide is contraindicated in the treatment of simple tics or tics other than those associated with Tourette's Disorder. (nih.gov)
Significant1
  • Based on the pharmacokinetic and metabolic profile, pimozide appears to undergo significant first pass metabolism. (nih.gov)
Disease1
  • These "transgenic" animals show a disease similar to human HD, and have become an important experimental system to study the disease-causing mechanisms. (utmb.edu)