Significantly years patient dropouts. Medical search. Frequent questions

The aim of this study is to evaluate the 2-years outcomes of repetitive doses of the transvaginal pudendal nerve injections (PNI) and to compare the success of the PNI concerning anatomical levels (endopelvic and extrapelvic portion) of the pudendal nerve pathology. (researchsquare.com)
Childhood-onset schizophrenia is a severe form of psychotic disorder that occurs at age 12 years or younger and is often chronic and persistently debilitating, with worse outcomes than patients who have later onset of symptoms. (medscape.com)
They instead suggested a cut-off age of 14.7 years of age based on higher levels of positive symptoms and poorer psychosocial functioning under this cut-off and better outcomes over this cut-off. (medscape.com)
At 5 years there was no longer any significant difference for clinical and radiographic outcomes between treatment strategies applied during the first 2 years. (bmj.com)
Findings to date Detailed clinical and laboratory data in high granularity as well as patient-reported outcomes from transplant recipients and activities in Switzerland are available in the last decade. (bmj.com)
US FDA Breast Implant Postapproval Studies: Long-term Outcomes in 99,993 Patients. (breastimplantinfo.org)
A study published in September 2018 in the medical journal Annals of Surgery , entitled US FDA Breast Implant Postapproval Studies: Long-term Outcomes in 99,993 Patients , concluded that "silicone implants are associated with an increased risk of certain rare harms" and that further study is needed "to inform patient and surgeon decision-making. (breastimplantinfo.org)
Cotton has carried out a range of academic research and surveys over the last few years, the findings of which she believes show that complex NHS data is not as representative as it should be when it comes to tracking IAPT outcomes. (politicshome.com)
Cotton argued that not acknowledging patients who drop out when calculating recovery rates allows NHS England to present a picture of a service that has better outcomes than it actually does. (politicshome.com)
I blog about therapist variables leading to poor outcomes, aspects of the therapeutic relationship and outcomes, and psychological therapies and patient quality of life. (uottawa.ca)

Methods Clinical and radiographic 5-year outcome was compared between initial strategies. (bmj.com)
This article will introduce an important research development to provide an evidence-based approach to current treatment methods and practices for young patients. (lww.com)
METHODS: A total of 40 swimmers, 20 girls (age: 13.70 ± 1.80 y, height: 161.65 ± 8.28 cm, body weight: 53.70 ± 8.65 kg) and 20 boys (age: 13.90 ± … 1.45 y, height: 160.95 ± 12.70 cm, body weight: 52.95 ± 12.64 kg), 13-16 y of age, at the competitive level were recruited. (iospress.com)
Methods: We included 886 participants older than 55 years (645 men and 241 women). (unav.edu)
Methods A total of 51 Spanish girls (age 7-16 years) with abdominal obesity underwent 8 weeks of a multidisciplinary intervention for weight loss. (unav.edu)
METHODS: Data on TKA patients (n = 570) from 2006 to 2007 were extracted from a single-institution registry. (ox.ac.uk)

Under intense stress patients with BPD may exhibit transient dissociative or paranoid symptoms. (wikipedia.org)
In patients with a history of autism spectrum disorder or a communication disorder of childhood onset, the additional diagnosis of schizophrenia is made only if prominent delusions or hallucinations, in addition to the other required symptoms or schizophrenia are also present for at least 1 month (or less if successfully treated). (medscape.com)
One study on the validity of a diagnosis of early-onset schizophrenia in Denmark found a correspondence of 88.8%, comparing the diagnosis listed in the Denmark registry to a clinical diagnosis based on symptoms reported in patient records. (medscape.com)
Though various authors have used varied definitions of treatment resistant schizophrenia, the most common definition of treatment resistant schizophrenia denotes patients who despite at least two adequate trials of classical neuroleptic drugs have persistent moderate to severe, positive, or disorganization, or negative symptoms together with poor social and work function over a prolonged period of time (Meltzer 1997). (priory.com)
Jalenques et al (1992), in an open prospective trial of clozapine in treatment resistant schizophrenic patients reported significant improvement in positive symptoms by 1 month and negative symptoms by 3 months with improvement in social functions and reduction in use of concomitant medications. (priory.com)
Treatment of UC focuses on induction of remission (treatment of symptoms of active disease) and prevention of clinical relapse (resumption of symptoms of active disease) in patients in remission (known as maintenance therapy). (cochrane.org)
Background -Several reports indicate that physical activity can reduce the severity of symptoms in depressed patients. (bmj.com)
For selected patients with moderate to severe major depression, aerobic exercise may result in a substantial improvement in symptoms in a short time. (bmj.com)
This study aimed to investigate feasibility including evaluation of a Zhineng Qigong intervention for pain and other lumbar spine-related symptoms, disability, and health-related quality of life in patients with chronic LBP and/or leg pain. (lu.se)
patients perceiving their symptoms as intense were more likely to be indicated for this treatment. (bvsalud.org)
Eating disorder symptoms and clinical variables were assessed in 168 obese female patients with DSM-5 BED or subthreshold BED, referred to a 6-month outpatient CBT program in a pre-post measurement design. (biomedcentral.com)
Patient reported impact of symptoms in amyotrophic lateral sclerosis (PRISM-ALS): A national, cross-sectional study. (cdc.gov)
Endometriosis is a benign gynecologic disease, although the associated symptoms can significantly affect a woman's quality of life. (medscape.com)

The positive effect of MTX was primarily linked to fewer dropouts because of adverse events. (bmj.com)
By making the clinical trial process more convenient for enrollment and participation, industry leaders can gain better research results, fewer failed trials, and more trust from physicians and patients. (within3.com)
In fact, compared to the non-fatigued patients, fatigued CML patients performed 1 hour less of physical activity per day and took 2000 fewer steps per day. (haematologica.org)
SAN DIEGO- If patients with gout keep their serum urate (SU) levels very low with urate-lowering therapy (ULT), they have fewer flares, according to a research abstract presented at ACR Convergence 2023. (the-rheumatologist.org)

This retrospective longitudinal cohort study consists of patients with PN diagnosed with the first four essential Nantes criteria. (researchsquare.com)
A cohort of older patients with bilateral cataract was assessed one week before and one to three months after first eye or both eye cataract surgery. (biomedcentral.com)
Results from the PARTNER 2, Cohort A trial showed that death or disabling stroke at 2 years-the trial's primary endpoint-were not significantly different for patients randomized to TAVR using the Sapien XT (Edwards Lifesciences) or open-heart surgery. (tctmd.com)
And when you do the subgroup analyses in the transfemoral cohort, which was 76% of the patients, it was significantly better than surgery for the primary endpoint of death and significant stroke. (tctmd.com)
The FRS significantly predicts CHD events in the ACLS cohort. (cdc.gov)
A recent publication updated the 1998 FRS and developed a have caused early drop-out, men with less than 1 year of follow-up new risk score that predicted an individual's cardiovascular dis- were excluded from the study's cohort (Figure 1). (cdc.gov)

The aim of the present work therefore was to present efficacy and tolerability data of TNF-blocking agents on PsA in clinical practice, and to study potential predictors for drug survival (the length of time a patient continues to take a particular drug). (bmj.com)
In this study, 220 CML patients receiving TKI therapy and 110 gender- and age-matched controls completed an online questionnaire to assess fatigue severity and fatigue predictors (Part 1). (haematologica.org)
Furthermore, clinicians are unable to identify patients at risk of fatigue since predictors have never been assessed in this specific population of patients. (haematologica.org)
Although a variety of predictors of fatigue, such as gender, age and socioeconomic status have been described in literature, 7-9 it is unknown whether these predictors, even when obtained in cancer populations, can be extrapolated to this unique group of CML patients on TKI therapy. (haematologica.org)
Aside from these unmodifiable predictors of fatigue, physical activity has been identified as a modifiable predictor of fatigue in several patient populations. (haematologica.org)
This study investigated changes in work participation and mental health, and predictors of RTW among patients being treated for common mental disorders (CMDs). (biomedcentral.com)
BACKGROUND: We investigated the predictors of long-term gains in quality-adjusted life years (QALYs) from total knee arthroplasty (TKA) and the patient attributes that predicted cost-effective TKA. (ox.ac.uk)
Multivariate linear regression analysis investigated the predictors of QALY gain from TKA from a broad range of preoperative patient characteristics and was used to predict QALY gains for each individual. (ox.ac.uk)
Predictors significantly associated with smaller QALY gains were comorbidities (Charlson comorbidity index 3+ coefficient -0.54 CI -0.15 to -0.92), the absence of severe osteoarthritis in the ipsilateral knee (-0.51 CI -0.16 to -0.85), preoperative HrQoL (standardized coefficient -0.34 CI -0.26 to -0.43), the requirement for an interpreter (-0.24 CI -0.05 to -0.44), and age (-0.01 CI -0.01 to -0.02). (ox.ac.uk)
This naturalistic and longitudinal study, following 557 outpatients who sought psychodynamic psychotherapy, aimed to verify factors associ- ated with non-indication for psychodynamic psychotherapy and to estab- lish predictors of non-agreement to initiate treatment for patients indicated for this treatment. (bvsalud.org)

On May 15, 2023, Pandemic Patients and COVID Survivors for Change hosted a Congressional briefing titled " Patient Perspectives on Long COVID . (pandemicpatients.org)
Cross-sectional and longitudinal analysis of Kobe City's administrative data on medical care, long-term care and public health services use and population health and lifestyle surveys for the years 2016 to 2023. (who.int)

Baseline data (patient characteristics, clinical status, generalized self-efficacy, expectations of future work ability) and treatment variables were used as independent variables in logistic regressions. (biomedcentral.com)
Dropouts did not report higher pain (baseline), only 3 dropped out because of lumbar spine-related pain. (lu.se)
Patients with and without involvement were compared on baseline characteristics and direct annual health care and criminal justice system-related costs. (mentalillnesspolicy.org)
They found that certain reduced amplitudes on pattern electroretinography (PERG) and microvasculature dropout at baseline were significantly associated with visual field progression. (reviewofoptometry.com)
Compared with glaucoma patients without progression, glaucoma patients with progression demonstrated frequent microvasculature dropout on OCT-A, isolated central scotoma, frequent disc hemorrhage and reduced baseline P50-N95 amplitude. (reviewofoptometry.com)
The researchers observed that age at diagnosis and baseline P50-N95 amplitude were significantly associated with mean deviation slope. (reviewofoptometry.com)
Additionally, microvasculature dropout and baseline P50-N95 amplitude were significantly associated with visual progression on the Humphrey GPA. (reviewofoptometry.com)

Landmark trials like PRoFESS help clinicians make evidence-based treatment choices and ensure that patients receive optimal therapy for their condition, said Professor Hans-Christoph Diener, MD, University of Essen, Germany, one of the three principal investigators of the study. (webwire.com)
Clinicians may want to consider extending the length of time their patients remain on prophylaxis to minimize flares. (the-rheumatologist.org)
The Framingham Risk Score (FRS) was de- narrows the heart's arteries and reduces blood flow to the heart veloped to help clinicians in determining their patients' CHD risk. (cdc.gov)
The clinicians on their patients' risk for CHD (8,9). (cdc.gov)

This review aims to present relevant findings published during the last 2 years related to medical and psychological treatment of anorexia nervosa, bulimia nervosa and avoidant/restrictive food intake disorder (ARFID). (lww.com)
Given the large percentage of women who were not in the study for more than 1 year, it is not possible to know how representative these findings are. (breastimplantinfo.org)
Our findings facilitate the identification of patients at risk of severe fatigue and highlight the importance to set the reduction of fatigue as a treatment goal in CML care. (haematologica.org)
1 , 2 However, care needs to be taken when applying these findings to patients with affective disorders. (bmj.com)
The findings of a study published in a supplement to the journal Neuropsychopharmacology showed that patients were initially stabilised with Abilify (aripiprazole) for at least six weeks following an episode of mania or a mixed episode - both mania and depression. (pharmatimes.com)
That said, he continued, "long-term durability assessments of transcatheter bioprosthetic valves are still lacking and extrapolation of these findings to low-risk patients requires further clinical trial evaluation. (tctmd.com)

Secondary effect parameters were adherence to supervised training, dropout rates, and hospitalization. (nih.gov)
Nevertheless, issues regarding adherence are common, such as poor patient compliance on homework assignments and therapists' drifting from strictly evidence-based CBT. (jmir.org)

Finally, a newly published, moderately large RCT of NAC (2,000 mg/d) in schizophrenia patients refractory to clozapine found that 1 year of treatment with NAC did not outperform placebo for any clinical, cognitive, or quality of life outcome. (psychiatrist.com)
Very many treatment strategies have been trialed for patients who do not recover completely. (psychiatrist.com)
Difficulties encountered in the treatment of patients suffering from PN are usually a result of its delayed diagnosis. (researchsquare.com)
Concomitant MTX and high CRP levels are associated with treatment continuation of anti-TNF therapy in patients with PsA regardless of joint distribution. (bmj.com)
Multiple regression analysis showed that early response to treatment is an independent predictor of 5-year outcome, irrespective of treatment strategy. (bmj.com)
Conclusions The difference in disease activity between treatment strategies disappeared over the years. (bmj.com)
Good-response to treatment independently predicts significantly better 5-year clinical and radiographic outcome. (bmj.com)
9 Disease activity during the first 3 months of treatment has been related to clinical and radiographic outcome after the first year of treatment, 6 10 11 and an early treatment response can predict the long-term work disability outcome. (bmj.com)
The present study investigates 5-year data of a 2-year methotrexate (MTX) based tight control treatment (TC) strategy compared to conventional MTX-based treatment (CT) strategy, and the (added) predictive value of an early response (at 6 months) to treatment for 5-year outcome with respect to disease activity and radiographic progression. (bmj.com)
Anorexia nervosa and atypical anorexia nervosa are by far the most prevalent eating disorders among patients admitted to child and adolescent psychiatric (CAP) treatment or to paediatric units with a CAP liaison service, whereas patients with bulimia nervosa and avoidant/restrictive food intake disorder (ARFID) are seen comparatively less often. (lww.com)
All these factors must be carefully considered and balanced in any individual COPD patient before adding ICS to her/his maintenance bronchodilator treatment. (ersjournals.com)
The treatment resistance of patients with schizophrenia is a frequent and important clinical problem. (priory.com)
The proportion of patients with treatment resistant schizophrenia has been consistent over time since the introduction of conventional antipsychotics (Conley and Buchanan, 1997). (priory.com)
The demonstration of efficacy of clozapine in treatment resistant schizophrenia has led to studies looking into the efficacy of various treatments in this patient group. (priory.com)
Clinical history (previous treatment) No good level of functioning over past 5 years Received 3 periods of treatment in preceding 5 years with antipsychotics of at least 2 different chemical classes for at least 6 weeks, with an equivalent of at least 1000 mg chlorpromazine daily without significant relief. (priory.com)
Fujii et al (1997) reported that patients with treatment resistant schizophrenia show significant global cognitive improvement, as measured by Wechsler Adult Intelligence Scale-Revised (WAIS-R) Full Scale, after a minimum of one year of treatment with clozapine. (priory.com)
Meltzer and Okayli (1995) have reported decrease in suicidality of treatment resistant schizophrenic patients with clozapine treatment of 6 months to 7 years duration. (priory.com)
Some mental health professionals believe the official figures are "disguising" failings in the system, which in reality sees many patients drop out of treatment. (politicshome.com)
Referrals to IAPT have been increasing year on year - reaching a record high in 2021/22 - and while NHS England reports that it has met government national targets to improve waiting list times and recovery rates, the system remains under immense pressure, with some people, including children and young people, still waiting more than a year for treatment. (politicshome.com)
Infection with human papillomavirus increases the probability of developing carcinoma of the cervix, which is the second leading cause of cancer- related mortality in females worldwide, killing some 240 000 women per year.1 Making a correct diagnosis of a sexually transmitted infection is essential for the provision of appropriate and effective treatment. (who.int)
2 CML patients require (potentially) lifelong treatment, which results in a persistent trigger for fatigue. (haematologica.org)
Drs. Karande and Klipstein chose the Ideal Protein Diet as a weight loss method for their patients based on its healthy approach and improved fertility treatment results. (inviafertility.com)
What is the optimal infertility treatment after age 40 years? (inviafertility.com)
Given the high prevalence of stroke and recurrent stroke in aging societies, physicians need a range of treatment options so they can offer patients a regimen tailored to their individual needs. (webwire.com)
Assessing work ability and expectations of RTW at the beginning of treatment is recommended to identify patients at risk of long-term sick leave. (biomedcentral.com)
However, not all patients benefit from CBT with prolonged exposure, and such treatment may be too difficult for some patients and therapists to tolerate. (uottawa.ca)
This study assessed the prevalence of encounters with the criminal justice system, encounter types, and the estimated cost attributable to these encounters in the one-year treatment of persons with schizophrenia. (mentalillnesspolicy.org)
This post-hoc analysis used data from an Eli Lilly-sponsored one-year multicenter, prospective, randomized open-label cost-effectiveness study of typical and atypical antipsychotics in the treatment of schizophrenia [ 13 ]. (mentalillnesspolicy.org)
Psychodynamic psychotherapy, as every other treatment, appears to be suitable for a specifi c group of patients. (bvsalud.org)
There were no missing data and no treatment dropouts. (jmir.org)
The study was undertaken to evaluate patient characteristics, (Age and sex distribution) long term sequelae of CNS prophylaxis (growth retardation) and the treatment outcome in these 66 paediatric patients who were treated and followed up at Cancer Institute, Maharagama, Sri Lanka during the period between 1st May 1982 and 27th September 1993. (who.int)
Eligible children aged 6-12 years attending primary health care centres with attention deficit hyperactivity disorder were randomly selected to receive tele- health collaborative care, or standard treatment. (who.int)
Our next step will be to analyze treatment patterns in those patients who did not receive medications. (cdc.gov)
These guidelines provide a framework for treatment for IC/BPS patients, while recognizing that IC/BPS has a wide array of clinical presentations that respond variably to different treatments. (cdc.gov)
We hoped that, by further examining treatment patterns, we can learn more about this complex disease and help target more effective treatments for patients. (cdc.gov)

Results 5 years of data were available for 205 of 299 patients, with no indication for selective drop-out. (bmj.com)
These results suggest that biologics have the potential to improve HRQL in UC patients. (cochrane.org)
Results: the intentional sampling consisted of a total of 385 Brazilian psychologists, mostly women (67.01%), young professionals with up to five years of graduation (44.16%) most of activities in the private clinic. (bvsalud.org)
Results support involvement of postoperative patients in a future study. (lu.se)
RESULTS: After exclusions and dropout, data were available for 488 patients. (ox.ac.uk)

The blockers were well tolerated with a rate of serious adverse events of 5-6% per year. (bmj.com)

Learn how to improve patient recruitment in clinical trials . (within3.com)
It will take dedicated scientists, advanced research initiatives, and skilled doctors with knowledge of the disease to conduct trials and care for as many patients as possible until we find a cure. (senate.gov)

Conclusions -Aerobic exercise can produce substantial improvement in mood in patients with major depressive disorders in a short time. (bmj.com)
Conclusions: An inverse association between cardiovascular health score and short telomeres was found especially for men older than 55 years in the SUN population. (unav.edu)

however, in a study which compared TFP, dialectical behavior therapy, and modified psychodynamic supportive psychotherapy, only TFP was shown to change how patients think about themselves in relationships. (wikipedia.org)
One study of 88 patients found the age cut-off of 12 years old to lack utility. (medscape.com)
In the Global Burden of Disease Study 2013, anorexia nervosa and bulimia nervosa combined were the 12th leading cause of DALYs in 15-19-year-old girls in high-income countries, accounting for 2.2% of all DALYs [1,2▪,3] . (lww.com)
Mentor's data are focused on patients' self-reporting on questionnaires, primarily on data of only 20% of the patients collected 7 years after the study was started. (breastimplantinfo.org)
As a result of the FDA's failure to enforce the study requirements, the large Allergan and Mentor studies used as the basis of the MD Anderson analyses were very flawed short-term studies rather than the 10-year studies that FDA had proudly said they were requiring. (breastimplantinfo.org)
Whereas the companies blamed the study shortcomings on the enormous number of women who "dropped out" of the study shortly after enrolling (including 80% of the women with Mentor implants after only 1 year), we have interviewed women who were enrolled in those studies who told us that they did not drop out of the studies - rather they were "dropped" from the study by the researchers without their consent. (breastimplantinfo.org)
The study that compared interferon-ß-1a to placebo found no clear evidence of a difference in the proportion of patients who experienced an improvement in HRQL at eight weeks. (cochrane.org)
Moderate quality evidence from the study comparing vedolizumab to placebo suggests that vedolizumab provides a clinically meaningful improvement in HRQL in UC patients receiving maintenance therapy. (cochrane.org)
High quality evidence from a study comparing golimumab to placebo suggests that golimumab patients had a better HRQL at six weeks than placebo patients. (cochrane.org)
The study included 613 methadone patients between April 1, 2003 and March 31, 2004. (biomedcentral.com)
The study was a prospective pre-post study of 164 patients treated at an RTW outpatient clinic for CMDs. (biomedcentral.com)
The aim of this study was to evaluate the association between ideal cardiovascular health (Life's simple 7) and the odds of having short telomeres in a subsample of participants older than 55 years from the Seguimiento Universidad de Navarra (SUN) study. (unav.edu)
This post-hoc analysis used data from a prospective one-year cost-effectiveness study of persons treated with antipsychotics for schizophrenia and related disorders in the United States. (mentalillnesspolicy.org)
To that end, a post-hoc analysis was conducted of data from a one-year cost-effectiveness naturalistic study of patients treated with antipsychotics for schizophrenia in the United States. (mentalillnesspolicy.org)
That study assessed several types of encounters the patients had with the criminal justice system, which enabled us to identify the prevalence of such encounters, characterize the specific types of legal encounters, estimate their direct costs, compare the health care costs between patients with and without any criminal justice system involvement, and estimate the proportion of the total health care cost attributable to patients' legal involvement. (mentalillnesspolicy.org)
The study included 221 black participants aged at least 65 years (mean age, 75.8 years) with MCI. (medscape.com)
The prospective study included 140 eyes with open-angle glaucoma, followed for three years. (reviewofoptometry.com)
The aim of the study was to explore whether personality functioning or personality traits are associated with Cognitive Behavioral Therapy (CBT) outcome in obese female patients with BED or subthreshold BED. (biomedcentral.com)
The study involved 15 patients with mild to moderate anxiety or depression (or both). (jmir.org)
The objective was to find the prevalence of acute diarrhoeal disorders among children aged 2-5 years in the estate population and to study the knowledge and practices of mothers regarding acute diarrhoeal disorders and to describe some socio-economic factors of these families. (who.int)
This retrospective study was carried out in 66 children ranging from 1 Â« years to 12 Â« years who were referred to Cancer Institute, Maharagama, Sri Lanka after being diagnosed as having Acute Lymphoblastic Leukaemia. (who.int)

A novel intervention that uses goal setting to promote a more active lifestyle significantly slows cognitive and functional decline in older black patients with mild cognitive impairment (MCI), new research shows. (medscape.com)
Cognitive rehabilitation through specific APP/software for PC/tablets represents an innovative intervention spreading in recent years. (uniroma1.it)
Onset of nodding occurs in previously healthy 5-15-year-old children and is often triggered by eating or cold temperatures and accompanied by cognitive impairment. (cdc.gov)

No difference in the primary endpoint was seen between patients treated surgically and those who underwent a transthoracic TAVR procedure. (tctmd.com)
152 patients (67.8% males) with brain tumours underwent a digital intervention. (uniroma1.it)

UC has a major impact on patients' health related quality of life (HRQL). (cochrane.org)
To determine the impact of cataract surgery on vision-related quality of life (VRQOL) and examine the association between objective visual measures and change in VRQOL after surgery among bilateral cataract patients in Ho Chi Minh City, Vietnam. (biomedcentral.com)
1 Nevertheless, health-related quality of life (QoL) of CML patients is inferior to that of the general population, which is mainly the result of TKI-induced fatigue. (haematologica.org)
Criminal justice system involvement was assessed using the Schizophrenia Patients Outcome Research Team (PORT) client survey and the victimization subscale of the Lehman Quality of Life Interview (QOLI). (mentalillnesspolicy.org)
QALY gains over 7 years post surgery were calculated from health-related quality of life (HrQoL) scores measured preoperatively and annually postoperatively using the short-form health survey (SF-12) instrument. (ox.ac.uk)
Late neurocognitive sequelae are common among long-term brain tumour survivors, resulting in significantly worse quality of life. (uniroma1.it)

Yolland et al 6 described a systematic review and meta-analysis of RCTs comparing NAC with placebo as antipsychotic augmentation in patients with schizophrenia or early psychosis. (psychiatrist.com)
antipsychotic medication Abilify significantly delayed relapses in adults with bipolar disorder over a two-year period. (pharmatimes.com)

The impressive speed at which COVID-19 vaccines reached the public was a win for pharma, but it also created intense pressure to repeat the feat. Acceleration is a buzzword for sure - not only from the perspective of patients who might receive life-changing treatments but for pharma companies and their bottom line. (within3.com)
Clinical trial timelines are designed to ensure that new treatments are safe and effective for patients. (within3.com)
Inclusion criteria for entering a MMT are opioid dependence, being at least 18 years of age, a positive toxicology test for heroin use, and failure in previous abstinence-oriented treatments. (biomedcentral.com)
The main technique of empirically validated psychological treatments for PTSD involve exposing patients to safe reminders of the trauma including memories, with the intent of extinguishing the fear responses. (uottawa.ca)
Despite evidence-based treatments a considerable number of BED patients fail to recover. (biomedcentral.com)

Patients received a 12-week training intervention with European Zhineng Qigong. (lu.se)
After this Zhineng Qigong intervention patients with chronic LBP and/or leg pain, also patients with considerable remaining LBP/sciatica after lumbar surgery, had significantly improved in pain and function. (lu.se)
The mean age at diagnosis and the intervention enrolment ranged from 4.9 to 9.4 years and 11.1 to 13.3 years, respectively. (uniroma1.it)
The dropout rate at 6 months in the control group was 80%, compared with 50% in the intervention group. (who.int)
early response also predicted 1-year success, suggesting that the 2-week point may be an ideal time to assess initial response and make intervention adjustments. (cdc.gov)

In logistic regression analysis, cocaine use was significantly associated with heroin use (OR 4.9). (biomedcentral.com)
Univariate analysis showed 13 out of 54 factors investigated were significantly associated with defaulting and, after stepwise logistic regression, 5 factors remained in the model: younger age (adjusted OR= 0.16), rural area of residence (OR = 12.9), long waiting times (OR = 5.81), poor physician-patient communication (OR = 3.06) and fear of information leakage (OR = 3.62). (who.int)

However, some studies revealed only transient positive effects with a significant number of dropouts during follow-up. (uniroma1.it)

Rodriguez et al (1998) compared clozapine responders, partial responders and non-responders from a group of resistant schizophrenic patients. (priory.com)

The validity of a diagnosis of childhood-onset schizophrenia has been a point of concern for some, due to difficulty in differentiating pediatric patients' reports of visual hallucinations from imaginary figures (which may be developmentally normal). (medscape.com)
Although prior research has assessed the mental health status of persons already incarcerated within the criminal justice system, little is known about schizophrenia patients' involvement in the US criminal justice system, the type of legal encounters they have, and the related direct economic cost. (mentalillnesspolicy.org)
Patients who were 18 years or older with a DSM-IV diagnosis of schizophrenia, schizoaffective, or schizophreniform disorder and a score of 18 or more on the Brief Psychiatric Rating Scale [ 14 ] were eligible to participate. (mentalillnesspolicy.org)

Thirty patients completed (mean 15 years symptom duration). (lu.se)

CONCLUSION: TKA is likely to be cost-effective for most patients except those with unusually high preoperative HrQoL or a lack of severe osteoarthritis. (ox.ac.uk)

by contrast, surgery-treated patients had more acute kidney injury, severe bleeding, and new-onset atrial fibrillation. (tctmd.com)

If we were able to delay the onset of Alzheimer's by just 5 years, similar to the effect that anticholesterol drugs have had on preventing heart disease, we would be able to significantly cut the government's spending on Alzheimer's care, but more importantly we would be able to give these families extra years, extra time, less time battling this disease. (senate.gov)
Investigations have confirmed a similar syndrome in Uganda and southern Sudan, in which the syndrome produced the characteristic clinical features, the age of onset was tightly clustered among children 5-15 years of age, and the reported incidence became higher during recent years ( Figure 1 ) ( 7 , 10 - 14 ). (cdc.gov)

Patients with vascular features who presented with central scotoma or possess retinal ganglion cell dysfunction detected by PERG tended to show progression," the researchers wrote in their paper. (reviewofoptometry.com)

Patients with BPD often experience intolerable feelings of emptiness that they attempt to fill with impulsive and self-damaging behaviors, such as substance abuse, risky sexual behavior, uncontrolled spending, or binge eating. (wikipedia.org)
EDE-Q global scores, self-reported binge eating frequency and BMI significantly decreased during CBT, where 44.3% of patients showed clinically significant change in EDE-Q global score. (biomedcentral.com)
Maladaptive ('neurotic') personality functioning is significantly associated with a less favorable outcome after CBT in patients with binge eating. (biomedcentral.com)
In 'subthreshold BED' all of the criteria for BED are met except that patients binge, on average, less than once a week or for less than 3 months. (biomedcentral.com)

The incidence rate of cataract was estimated at 170,000 cases per year [ 2 ]. (biomedcentral.com)

Four hundred and thirteen patients were assessed before cataract surgery and 247 completed the follow-up assessment one to three months after first or both eye cataract surgery. (biomedcentral.com)
Pain was assessed using visual analogue scores (VAS) every 6 months for 2 years. (medscape.com)
Success, or achievement of weight-reduction goal, at 6 months, 1 year, and 2 years was defined as a weight reduction of 5% or more. (cdc.gov)
When matched with non-IC controls, patients with IC/BPS had $7,223 higher total health care costs in the first twelve months after diagnosis. (cdc.gov)

Poor ovarian response (POR) occurs in approximately 9.24% of patients undergoing in vitro fertilization (IVF). (inviafertility.com)

Other autoimmune and rare diseases were also significantly higher among women with Mentor silicone gel implants. (breastimplantinfo.org)
These diagnoses were also statistically significantly higher (although not as dramatically increased) for women with Allergan implants compared to the general population of women of similar demographics. (breastimplantinfo.org)
They found that on the average: systolic blood pressure was almost 19 mm Hg different (higher) in the physicians office diastolic blood pressure was 11 mm Hg different (higher) in the doctor's office there was poor correlation between the readings conducted in the doctor's office versus readings that patients and others obtained themselves by ambulatory measurement. (wdxcyber.com)
1 Sara K. Tedeschi, MD, MPH, assistant professor of medicine at Harvard Medical School and rheumatology director at Brigham and Women's Hospital, Boston, and colleagues concluded that gout flare rates were persistently higher when SU was ≥6 mg/dL compared with SU at target after the first year of urate lowering therapy. (the-rheumatologist.org)
That meant that every patient in both groups had to be seen by a neurologist before the procedure, after the procedure, before discharge, and at follow-up, and the ascertainment of stroke is always much higher when you do that," Leon explained. (tctmd.com)

Its incidence has increased in Uganda and South Sudan over the past 10 years. (cdc.gov)
CHD incidence in the past 30 years (7). (cdc.gov)

Objective: to verify associations between sociodemographic variables and factors that facilitate and hinder the transition from face-to-face psychological care to remote mode in the first year of the COVID-19 pandemic. (bvsalud.org)
During the coronavirus pandemic, Andrew co-founded Pandemic Patients and currently serves as the President of the organization. (pandemicpatients.org)
Alongside his work with Pandemic Patients, Andrew also helps long COVID patients access disability benefits and safety net resources while working to enforce their rights if they are the victim of disability discrimination in the workplace. (pandemicpatients.org)
To describe the behavioural changes among the population 20 years and older, in Kobe City, Hyogo Prefecture, Japan, before and after the COVID-19 pandemic, and the effects of these behavioral changes on the health of this population. (who.int)

Since patients' self-reports at 7 years would be expected to include more complications than physicians' diagnoses after 2 years, it is impossible to make meaningful comparisons between the two manufacturers. (breastimplantinfo.org)

For other disease areas - rare diseases, oncology, and gastrointestinal conditions - enrollment can take years, significantly affecting trial success. (within3.com)

The efficacy of the PNIs significantly declined over time. (researchsquare.com)
Patients (n = 261) with active PsA, starting anti-TNF therapy for the first time in southern Sweden, were included. (bmj.com)
They say that while the average number of people receiving a first talking therapy appointment within the targeted time is exceeding expectations, the number of those who go on to complete the course is significantly lower. (politicshome.com)
If drug developers can accelerate time-to-market by three to five years and extend the number of years before patent expiry, the value of acceleration is significant. (within3.com)
It was found that training time between five and 10 years was associated with a greater perception of difficulties and that previous experience with remote care facilitated adaptation in the transition from one modality to another. (bvsalud.org)
Compared with osmotic dilators misoprostol gives equal cervical dilatation in a shorter time, is easier to administer and is more convenient to the patient. (fiapac.org)
1. Among typical couples who initiate use of a method (not necessarily for the first time), the percentage who experience an accidental pregnancy during the first year if they do not stop use for any other reason. (rxlist.com)
Questioned about this point during the late-breaking clinical trial session, Smith commented: "My own guess is that, as time goes on, there will be still be some patients who can't have transfemoral TAVR and shouldn't have surgery and still need some other access route to have TAVR. (tctmd.com)
These individuals are imprisoned about 8 times more frequently than they are admitted to state mental hospitals [1] and are incarcerated for significantly longer time than other inmates [ 2 ]. (mentalillnesspolicy.org)
All patients had complete resection of all endometriotic lesions at the time of laparoscopy. (medscape.com)

Gina Assaf is a Long COVID patient advocate who has made significant contributions to the field of patient-led research for Long COVID. (pandemicpatients.org)

The criteria included the aspects of patients' clinical history, cross-sectional measures and prospective assessments (Table-1). (priory.com)

Objective -To evaluate the short term effects of a training programme on patients with moderate to severe major depression. (bmj.com)
CHICAGO, IL-Transcatheter aortic valve replacement using a second-generation balloon-expandable device is at least as good as surgery in intermediate-risk patients with severe symptomatic aortic stenosis. (tctmd.com)
PARTNER 2A randomized 2,032 intermediate-risk patients with severe symptomatic aortic stenosis at one of 57 centers to either open surgical valve replacement or transcatheter aortic valve implantation with the Sapien XT. (tctmd.com)

To examine whether maintenance training (MT) for 1 year improved the long-term effects of a 7-week chronic obstructive pulmonary disease (COPD) rehabilitation program. (nih.gov)
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the management of patients with chronic obstructive pulmonary disease (COPD) is much debated. (ersjournals.com)

There was no difference between the 2 groups regarding dropout rates or hospitalization. (nih.gov)
Later RCTs of ICS/long-acting β 2 -agonist (LABA) combinations generally recruited patients with ≥1 ECOPD in the previous year, and showed that ICS/LABA combinations reduce ECOPD rates by approximately 25-35% compared with LABA monotherapy ( figure 1 ) [ 3 - 14 ]. (ersjournals.com)
More recently, two RCTs (IMPACT and TRIBUTE) compared triple therapy versus LABA/long-acting muscarinic antagonist (LAMA) combinations in patients at high ECOPD risk, and also showed a 15-25% reduction in ECOPD rates ( figure 1 ) [ 17 , 18 ]. (ersjournals.com)
Atkinson, who delivers free therapy to people on low incomes in east London, believes that despite a strong correlation between social deprivation and mental health problems, NHS England "ignores" long term recovery rates and does not sufficiently investigate the living conditions of patients. (politicshome.com)
The effort comes in the midst of news that Obamacare, as the Affordable Care Act is commonly known, will significantly raise insurance premiums in some states, and may increase rates for many hourly wage-earners. (heartland.org)
In the initial year of ULT, flare rates did not significantly differ between SU groups, but flare rates were consistently highest when SU was ≥10 mg/dL. (the-rheumatologist.org)
Rates of disabling stroke were not significantly different between groups at 2 years, despite the fact that in PARTNER 2, the US Food and Drug Administration (FDA) mandated neurology oversight. (tctmd.com)
Early data suggest that stroke rates are even lower with the lower-profile Sapien 3 device (Edwards Lifesciences), which is the subject of another late-breaking clinical trial presentation tomorrow, also in intermediate-risk patients. (tctmd.com)

We sampled female patients with an ICD-9/10 diagnosis of IC/BPS (595.1/N30.10) by querying active users of the Veterans Health Administration. (cdc.gov)

High quality evidence suggests that infliximab provides a clinically meaningful improvement in HRQL in UC patients receiving induction therapy. (cochrane.org)
High quality evidence shows that TNF-α antagonists (as a class of biologics) provide a clinically meaningful improvement in HRQL in UC patients receiving induction therapy. (cochrane.org)
Future research should also focus on determining whether golimumab and adalimumab can provide UC patients with a clinically meaningful improvement in HRQL. (cochrane.org)

After a 7-week outpatient rehabilitation program, 96 patients with COPD were randomized to either an MT group (n = 55) or a control group (n = 41). (nih.gov)
Here, we review the evidence available for ("friend") and against ("foe") ICS use in COPD and propose that ICS, added to one or two long-acting bronchodilators (never as stand-alone medication), can benefit some (but not all) COPD patients. (ersjournals.com)
Many studies have explored the efficacy and safety of ICS in patients with COPD. (ersjournals.com)

This gives great opportunities to choose the most convenient regimen depending on patient preference and practical aspects. (fiapac.org)

We designed a support system accessible via the Internet (using a computer or an Apple iPad) for patients and therapists delivering CBT face-to-face. (jmir.org)

Fatigue is a common side effect of tyrosine kinase inhibitor (TKI) therapy in chronic myeloid leukemia (CML) patients. (haematologica.org)
We believe that the use of NASA LED for light therapy alone, and in conjunction with hyperbaric oxygen, will greatly enhance the natural wound healing process, and more quickly return the patient to a preinjury/illness level of activity. (researchgate.net)
The patients were randomly assigned to no additional therapy after surgery (non-users), cyclic OC use, or continuous OC use. (medscape.com)

Programmes and interventions have in recent years been developed to facilitate return to work (RTW) after sickness absence because of mental disorders [ 3 ]. (biomedcentral.com)
She is the co-founder and co-lead of Patient-Led Research collaborative (PLRC), a global collaborative whose mission is to facilitate patient-led research into Long COVID while following rigorous research methodology. (pandemicpatients.org)

Patient attribute differences between deciles were decomposed. (ox.ac.uk)

Objective monitoring of activity patterns confirmed that fatigued CML patients performed less physical activity on both light (P=0.017) and moderate to vigorous intensity (P=0.009). (haematologica.org)

Of the 6,183 participants in this analysis, the median age was 65 (IQR 58-71) years and 84.0% were men. (the-rheumatologist.org)

The estimated proportion of incident AMR GC infections in men with urogenital GC in 2018 was 51.5% (95% CI: 50.1% - 52.9%), equating to an estimated 366,300 incident AMR GC infections in US men aged 15-39 years. (cdc.gov)

Detecting progression in normal-tension glaucoma patients can be challenging, as more than half of untreated patients may not display visual field progression for many years. (reviewofoptometry.com)

However, it is recommended to perform therapeutic nerve blocks even in patients with suspected endopelvic pudendal nerve pathology before the referral to surgery. (researchsquare.com)

Stroke is the third leading cause of death in developed countries after coronary heart disease and cancer.4 Patients who survive a first stroke are at a high risk of a first recurrent stroke.5 PRoFESS is the first trial to directly compare the efficacy and safety of the two antiplatelet agents, ER-DP plus aspirin and clopidogrel, in the prevention of recurrent stroke after non-cardioembolic ischaemic stroke. (webwire.com)

Psychiatry and Psychology1

Anthropology, Education, Sociology and Social Phenomena1

Named Groups2

Outcomes10

Methods6

Symptoms13

Fewer4

Cohort6

Predictors10

20232

Baseline7

Clinicians4

Findings6

Adherence2

Treatment35

Results5

Adverse events1

Trials2

Conclusions2

Study21

Cognitive3

Underwent2

Quality of l6

Antipsychotic2

Treatments5

Intervention5

Logistic regression2

Transient1

Clozapine1

Schizophrenia3

Duration1

Conclusion1

Acute1

Onset2

Vascular1

Binge4

Rate1

Months4

Ovarian1

Higher5

Incidence2

Pandemic4

Complications1

Rare diseases1

Time10

Significant1

Prospective1

Severe3

Chronic obstruc2

Rates8

Diagnosis1

Clinically3

COPD3

Regimen1

Therapists1

Therapy3

Facilitate2

Differences1

Moderate1

Participants1

20181

Progression1

Therapeutic1

Recurrent1