• During chemotherapy, intestinal permeability was assessed by lactulose/mannitol (La/Ma) urinary test on days 0 and 14. (naturalmedicinejournal.com)
  • During chemotherapy, the lactulose-mannitol ratio increased significantly by day 14 from baseline. (naturalmedicinejournal.com)
  • Intestinal permeability was assessed before and after treatment by giving a lactulose-mannitol (LM) drink and measuring urinary recovery after 5 hr. (greenmedinfo.com)
  • An alternative, urine test indicating either malabsorption or leaky gut is the lactulose-mannitol test (less commonly, also lactulose/rhamnose test). (healthknot.com)
  • The purpose of this study was to compare the relative effects of mannitol and hypertonic saline (HTS) on calpain activity, apoptosis and neuroinflammatory response induced by experimental cortical contusion. (biu.ac.il)
  • It would make sense that the effects of mannitol would be different for different people, because alpha-synuclein (misfolded proteins, the basis of Parkinson's Disease), can start in different places in the brain and spread from there. (parkinsonsnewstoday.com)
  • Mannitol is an osmotic diuretic. (nih.gov)
  • Such mannitol is excreted by the kidneys and produces osmotic diuresis. (nih.gov)
  • Exposure of isolated bovine coronary arteries to high glucose (30 mmol/l d -glucose) but not to osmotic control mannitol (30 mmol/l) switched angiotensin II-stimulated prostacyclin (PGI 2 )-dependent relaxation into a persistent vasoconstriction that was sensitive to either indomethacin, a cyclooxygenase inhibitor, or SQ29548, a selective thromboxane receptor antagonist. (diabetesjournals.org)
  • Sucrose, glucose and mannitol were added to the culture media (individually and in combination) at O to 90 mM to determine whether they have a nutritive, osmotic or combined effect on growth. (edu.au)
  • Uosm after increasing osmotic load with mannitol infusions. (biomedcentral.com)
  • We usually add 8% (mass ratio by volume) of trehalose and mannitol as lyoprotectant. (stratech.co.uk)
  • The sequence has facilitated experiments that have defined roles for the Ca2+/calmodulin, MAP kinase and cAMP-dependant signalling pathways and for the metabolites mannitol, arabitol, xylitol, malate, trehalose and aminolevulinate. (usda.gov)
  • Sweeteners like sorbitol and mannitol are poorly absorbed and fermented. (hepatitisfoundation.org)
  • Mannitol is poorly absorbed from the gastrointestinal tract. (nih.gov)
  • This newly defined enteroenteric response occurs independently of nutrient composition and responds to increasing osmolarity of poorly absorbed solutes such as mannitol. (johnshopkins.edu)
  • These two sugars that cannot be metabolized differ significantly in their molecular size, mannitol having small, easily absorbable molecules, as opposed to large, poorly absorbed lactulose molecules. (healthknot.com)
  • In parallel, high glucose, but not mannitol, significantly increased superoxide and 3-nitrotyrosine in PGI 2 synthase (PGIS). (diabetesjournals.org)
  • Growth in the no carbohydrates treatments was significantly reduced compared with treatments containing glucose and/or sucrose. (edu.au)
  • The expressions of NLRP3, ASC, caspase-1, IL-1β, and IL-18 in rat glomerular mesangial cells were significantly higher in the high glucose (HG) group than in the control normal glucose (NG) group and exhibited time-dependence activity. (biomedcentral.com)
  • Methods: Intravital videomicroscopy of the rat jejunum was used to record the vascular responses of inflow (termed 1A) arterioles, proximal (p3A), and distal (d3A) premucosal arterioles during exposure to isotonic glucose or mannitol solutions alone or in the presence of the selective nitric oxide synthase (NOS) inhibitor (L-NMMA), an adenosine A1 receptor antagonist (8-cyclopentyl-1,3-dipropylxanthine (DPCPX)), or a K + ATP channel inhibitor (glibenclamide). (arizona.edu)
  • Results: As expected, glucose exposure caused rapid dilation of both p3A and d3A arterioles, while mannitol exposure had no effect on microvascular diameters. (arizona.edu)
  • NOS inhibition significantly blunted the glucose-induced vasodilation of the premucosal arterioles, but had little effect in the mannitol group. (arizona.edu)
  • Shift of sodium-free intracellular fluid into the extracellular compartment after mannitol infusion may lower serum sodium concentration and aggravate preexisting hyponatremia. (nih.gov)
  • Inadequate urine output results in accumulation of mannitol, expansion of extracellular fluid volume and could result in water intoxication or congestive heart failure. (nih.gov)
  • We examined the effect of carrier material and storage conditions on the populations of two industry standard rhizobia, Bradyrhizobium japonicum USDA 110 for soybean ( Glycine max ) and Rhizobium tropici CIAT 899 for common bean ( Phaseolus vulgaris ) over 165 days, using the drop plate method on Congo Red Yeast Extract Mannitol Agar. (n2africa.org)
  • Samples were collected at the endodontics clinic of São Leopoldo Mandic Dental School, Campinas, São Paulo, Brazil and then inoculated in brain heart-infusion (BHI) agar and mannitol salt agar. (bvsalud.org)
  • Mannitol occurs naturally in fruits and vegetables, and is metabolically inert in humans. (nih.gov)
  • Serum sodium and potassium should be carefully monitored during mannitol therapy. (nih.gov)
  • All serum electrolytes evaluated were significantly altered in the three groups, without important clinical signs. (nih.gov)
  • scavenger), or thiourea (intracellular OH · radical scavenger) significantly depressed the 5-HT-induced contractions in the aortic rings. (ias.ac.in)
  • D-mannitol and adipic acid, present different phase change temperatures, 164 ° C for D-mannitol and 152 ° C for adipic acid. (scirp.org)
  • Irrigating solutions used in transurethral prostatectomy have been shown to enter the systemic circulation in relatively large volumes, exert a systemic effect and may significantly alter cardiopulmonary and renal dynamics. (nih.gov)
  • C. Minimize pill burden and ing or crushing of tablets with lactose or mannitol as a guide to drugs that physically carries of gated response) macotherapy responsiveness is significantly more stable ponderosum quality can have downstream effect on the emulsifying agent magnesium stearate as force control agent to provide an introduction to the conjunctival sac. (stonecottagegardens.com)
  • Although mannitol proved to significantly decrease the neuroinflammatory response and calpain activity, it did not affect apoptosis, and its effect was significantly less than that of HTS. (biu.ac.il)
  • I have had Parkinsons since 2011 and nothing else I have done has had the effect that Mannitol has. (parkinsonsnewstoday.com)
  • GLP-2 levels on day 14 were significantly lower than on day 0 and day 3, while EGF values were significantly lower on day 10 than at the baseline. (naturalmedicinejournal.com)
  • Patients with diarrhea had significantly lower GLP-2 and higher ghrelin levels. (naturalmedicinejournal.com)
  • Leptin and BDNF were significantly higher, and neurotensin levels were significantly lower in D-IBS(+) than in controls. (hindawi.com)
  • the mean GFR was statistically significantly lower than that for normal bitches. (biomedcentral.com)
  • Being mindful of dietary choices can significantly reduce troublesome gas and bloating episodes. (hepatitisfoundation.org)
  • These players are actively contributing to the growth of the mannitol market through innovative solutions and strategic initiatives. (brilad.com)
  • All patients showed significantly increased intestinal permeability and shifts in GLP-2, ghrelin, and EGF. (naturalmedicinejournal.com)
  • Mannitol solution must be used with caution in patients with significant cardiopulmonary or renal dysfunction. (nih.gov)
  • D-IBS(−) patients had a significantly higher GSRS cluster pain and diarrhoea profile than D-IBS(+) ones. (hindawi.com)
  • With China and India leading the trend, the growing number of diabetic patients in Asia Pacific is set to provide ample opportunities for the mannitol market's expansion. (brilad.com)
  • The global mannitol market , currently valued at over US $300 Mn , is expected to experience significant growth in the long term as mannitol gains traction worldwide as a low-calorie sweetening agent. (brilad.com)
  • Mannitol's expanding application base across various industries, including pharmaceuticals, food and beverages, medical, and analytical chemistry, is a key driver for the growth of the global mannitol market. (brilad.com)
  • The cost-effective production of mannitol and its wide-ranging applications, including use as a food additive, are expected to propel the growth of the mannitol market. (brilad.com)
  • Economic development and changing lifestyles have led to a higher demand for packaged and convenience foods, creating a market for artificial sweeteners like mannitol. (brilad.com)
  • Oocytes pulsed in media containing 0.9 mM Ca$\sp{2+}$ exhibited significantly higher rates of activation (P $ (lsu.edu)
  • Significantly higher rates of fusion were obtained in PBS medium than 0.3 M mannitol (P $ (lsu.edu)
  • Majority of the mannitol (drought)-inducible genes were also induced by salt, high temperature stresses and ABA. (icrisat.org)
  • The extract is reduced in volume, an internal standard added (1,5-anhydro-D-mannitol), and a portion of the extract derivatized with 10% by volume N-trimethylsilylimidazole. (cdc.gov)
  • As consumer demand for low-calorie alternatives grows, the beverage sector is also embracing mannitol as a sugar substitute in products like coffee, juices, and flavored drinks. (brilad.com)
  • SbNF-YA1, 2, and 6 were found upregulated under 200 mM salt and 200 mM mannitol stresses. (icrisat.org)
  • Mannitol solution, 2.5% is indicated as an irrigation solution in transurethral prostatic resection or other transurethral surgical procedures. (nih.gov)
  • The diuresis after rapid infusion of mannitol may increase preexisting hemoconcentration. (nih.gov)
  • The goal of this work was to measure the heat transfer rates from thermofluid, Therminol 66, to two phase change materials, D-mannitol and adipic acid. (scirp.org)
  • The average heat transfer coefficient, during the phase change process, was of 340 W/(m 2 K) for D-mannitol and 1320 W/(m 2 K) for adipic acid. (scirp.org)
  • It was once thought that salivary function did not change significantly with age. (medscape.com)
  • A positive result for pANCAs was significantly associated with hypoalbuminemia, and pANCAs preceded the onset of hypoalbuminemia on an average of 2.4 years. (avma.org)
  • Wow, it is great to hear that some people are having positive responses to mannitol! (parkinsonsnewstoday.com)
  • The etiologies of the crisis, the perioperative team knowledge of the patient's comorbidities, the awareness of current physiological state, and the immediate rescue response time significantly improve restoration of spontaneous circulation and survival to discharge when compared to other forms of IHCA. (medscape.com)
  • With continued use of mannitol a loss of water in excess of electrolytes can cause hypernatremia. (nih.gov)
  • Progressive renal damage or dysfunction after institution of mannitol therapy, including increasing oliguria and azotemia. (nih.gov)
  • Surface Active Agent - Surfactants, for instance, polyethylene glycol glycerol can be used to prepare lipid-based formulations that significantly improve solubility and thus oral bioavailability through various self-emulsifying systems. (selfgrowth.com)
  • The presence of inhalation injuries significantly increases the morbidity and mortality.1 The mechanisms of inhalation injuries can be divided into three categories. (openanesthesia.org)
  • Emerging economies such as India and China are expected to contribute significantly to the market. (brilad.com)
  • Though aminotriazole partially inhibited the catalase activity, it inhibited 5-HT-induced contractions significantly. (ias.ac.in)