Significantly immune sera. Medical search. Frequent questions

The antiphospholipid syndrome (APS) is a systemic autoimmune inflammatory disease characterized by the presence of serum antiphospholipid antibodies (aPL) and clinically by vascular thrombosis and/or obstetric events ( 1 ). (frontiersin.org)
Particularly, the induction of antibodies that neutralize the virus are critical for the protective humoral immune response and level of those neutralizing antibodies have been reported to correlate with the severity of COVID-19 5 . (researchsquare.com)
Those antibodies are substantially directed against the viral surface protein Spike 6 and decreasing titers over time lead to reduced protection ("immune waning") 7 - 10 . (researchsquare.com)
Criteria for a VOC include increased transmissibility, virulence /clinical disease or decrease of effectiveness of therapeutic measurements such as immune escape from current vaccines-induced antibodies 11 . (researchsquare.com)
The level of anti-DNA antibodies in sera were significantly higher in lpr mice. (nih.gov)
Additional controlled, longitudinal studies may expound the significance of serum antibodies as potential markers for periodontal disease. (scirp.org)
These results indicate an immune escape focused on neutralizing antibodies. (nih.gov)
Unexpectedly, injections of recombinant ACPAs significantly reduced paw thickness and arthritis severity in CAIA mice, as compared to isotype-matched control antibodies (p≤0.001). (stanford.edu)
Results indicate that patients with immune-mediated disease were less likely to have detectable antibodies than healthy controls among hospital workers and among the elderly population included in this study. (indianactsi.org)
Those using immunosuppressive or immune-modulating drugs were significantly less likely to have detectable antibodies when compared to those off treatment. (indianactsi.org)
antibodies in feline sera were not significantly different for cats with and without disease. (vin.com)
Serum anti-glycan antibodies are potential biomarkers for tracking response to cancer vaccines. (nih.gov)

Although innate immune responses to AP have been studied extensively, investigations on the adaptive IS are scarce. (nih.gov)
Dong W, Qiu C, Shen H, Liu Q, Du J. Antitumor Effect of Embryonic Stem Cells in a Non-Small Cell Lung Cancer Model: Antitumor Factors and Immune Responses. (medsci.org)
In this study, non-small cell lung cancer cells (Lewis Lung Carcinoma cells, LLCs) and ESCs were co-injected together into mice, after that subcutaneous tumor growth was monitored, cellular and humoral immune responses were detected, and different control groups were set to compare the results in different conditions. (medsci.org)
We conclude that the boosted antitumor effects induced by ESCs and cancer cells co-injection may be both the effects of antitumor factors secreted by ESCs and immune responses induced by ESCs in vivo. (medsci.org)
As expected, the results showed that ESCs co-injected with cancer cells could induce stronger anticancer immune responses in vivo, with more CD8+ lymphocytes generated and higher anticancer cytokine level (IL-2 and IFN-γ) compared to be injected alone. (medsci.org)
Detection of host immune responses in acute phase sera of spontaneous resolution versus persistent hepatitis C virus infection. (nih.gov)
Viral transmission in subjects with a known date of infection allows the study of the immune responses to acute HCV infection. (nih.gov)
5 Significantly, the protein produced from the natural version of the same gene in beans does not cause these responses. (hawaiiseed.org)
The study shows that heedlessly transferring genes from one organism to another via genetic engineering can have health conse-quences, including allergies and other adverse immune responses. (hawaiiseed.org)
A failure in autophagy is associated with a variety of diseases including the cellular immune responses caused by pathogenic microorganisms [ 18 ]. (biomedcentral.com)
The formation and deposition of immune complexes (ICs) in various tissues and organs result in local inflammatory responses and severe tissue destruction including the brain, blood, heart and kidney [ 1 ]. (biomedcentral.com)
Lipopolysaccharide (LPS), a potent endotoxin present in the outer membrane of Gram‑negative bacteria, causes chronic immune responses associated with inflammation. (spandidos-publications.com)
LPS induces inflammation via a cascade of inflammatory responses following the recognition of lipid A of LPS by immune cells ( 12 , 13 ). (spandidos-publications.com)
Objective -To study the effects of a synthetic, dog-appeasing pheromone (sDAP) on the behavioral, neuroendocrine, immune, and acute-phase perioperative stress responses in dogs undergoing elective orchiectomy or ovariohysterectomy. (avma.org)
Variables examined to evaluate the hypothalamic-pituitary-adrenal axis, immune system, and acute-phase responses were unaffected by treatment. (avma.org)
These results indicate that the type of immune responses to pDNA immunization in mice is strain dependent. (tmu.edu.tw)
Although tumors and many vaccines express antigenic carbohydrates, immune responses to these carbohydrates are relatively understudied. (nih.gov)
These results provide the first evidence of enhanced vaccine efficacy associated with immune responses to glycans displayed on a cancer vaccine. (nih.gov)
as well as innate immune responses of rainbow trout fry challenged with Aeromonas hydrophila. (cmu.ac.th)
The present findings indicate that dietary administration of inulin promotes growth and biochemical parameters, as well as serum immunity and mucosal immune responses of rainbow trout, in which a 2% inclusion produced the best results. (cmu.ac.th)
To evaluate the reactogenicity and humoral as well as cellular immune responses towards most prevalent SARS-CoV-2 variants after a heterologous ChAdOx1 nCoV-19 BNT162b2 prime-boost vaccination, we analysed a cohort of 26 clinic employees aged 25-46 (median 30.5) years who received a ChAdOx1 nCoV-19 prime followed by a BNT162b2 boost after an 8-week interval. (unboundmedicine.com)
In conclusion, heterologous ChAdOx1 nCoV-19 / BNT162b2 prime-boost vaccination is not associated with serious adverse events and induces potent humoral and cellular immune responses. (unboundmedicine.com)

Our results suggested that compared to be injected alone, ESCs co-injected with cancer cells could inhibit cancer cell growth more efficiently in vivo, with more CD8+ lymphocytes generated in both peripheral circulation and spleen, and with higher serum anticancer cytokine level (interleukin (IL)-2 and interferon (IFN)-γ). (medsci.org)
Altered serum and gingival crevicular fluid inflammatory cytokine profiles, immune cell function, and altered proteolytic regulations are noticed in smokers. (scirp.org)
Tryptophan degradation by the enzyme indoleamine-(2,3)-dioxy genase (IDO) and neopterin production are induced within cellular immune activation by stimulation of monocyte-derived macrophages and dendritic cells with cytokine interferon-gamma. (nih.gov)
In addition, polymorphisms in immune regulating cytokines are associated with NHL risk and cytokine deregulation can predict response to RCHOP. (confex.com)
To investigate immune cell and cytokine deregulation in DLBCL. (confex.com)
To identify co-deregulated immune cell / cytokine relationships in DLBCL contributing to R/R disease we used correlation analysis across PBMC populations, differentiating clusters and cytokine levels. (confex.com)
TGFβ1 was initially identified as a potent chemotactic cytokine to initiate inflammation, but the autoimmune phenotype seen in TGFβ1 knockout mice reversed the dogma of TGFβ1 being a pro-inflammatory cytokine to predominantly an immune suppressor. (ijbs.com)

Hence, the present study was undertaken to assess the impact of smoking on serum immunoglobulin G (IgG) levels in smokers with periodontitis and its potential role as a risk indicator of the disease process. (scirp.org)
Serum immunoglobulin IgG was estimated with immunoturbidimetric assay. (scirp.org)
Shrestha, C. , Uppoor, A. and Nayak, D. (2014) Impact of Smoking on Serum Immunoglobulin G Levels in Patients with Periodontitis. (scirp.org)

Recognition of viral infection by the innate immune system occurs through the cytoplasmic recognition of cellular receptors of viral nucleic acids. (medscape.com)
The chronic low-grade inflammation activates the innate immune system that subsequently leads to insulin resistance and further leads to type II diabetes mellitus. (hindawi.com)
Dysfunction has been defined for both innate immune system providing natural resistance to infections and tumorigenesis, and the adaptive system for acquired and long-preserving immunity. (oncotarget.com)

Serum cryoglobulin and autoantibody levels increase, as does the presence of high-molecular-weight immune complexes. (medscape.com)
Quantitative profiling to understand proteome alterations along with comprehensive autoantibody profiling of serum, urine and CSF samples. (um.edu.my)
Decreased levels of total IgG and autoantibody were detected in the serum with less deposition of immune complexes and attenuated pathological symptoms in the kidneys of Lrrk2 − / − mice. (biomedcentral.com)

Serum antibody titers were significantly lower against Omicron RBD compared to the original Wuhan strain. (nih.gov)
Those on rituximab and other immunosuppressants had significantly reduced antibody titers as did those over 60 years of age. (indianactsi.org)

Serum sCD40Lshowed statistically-significant high levels in HCV-HCC patients compared to HCV-cirrhotic patients and normal controls (P (who.int)

Monitor renal function, including blood urea nitrogen, serum creatinine, and urine output in patients at risk of acute renal failure. (nih.gov)
These findings, along with significant detection levels in serum and urine, support PFAS-induced liver damage and PPARa, d, and gamma involvement in alternative PFAS systemic toxicity and immunological disruption. (cdc.gov)

Serum cholesterol concentrations in rats given both colchicine and indomethacin were similar to control values. (karger.com)
The different components and concentrations of nutrients or metabolites affect immune cell function and help determine the outcome of the battle between tumors and host immunity [ 19 ]. (biomedcentral.com)
Concentrations of tryptophan and kynurenine were measured by HPLC in sera of patients, and to estimate IDO activity, the kynurenine to tryptophan ratio was calculated. (nih.gov)
Kynurenine concentrations (median: 1.91 vs. 1.73 microM in controls) and kyn/trp (median: 41 vs. 35 micromol/mmol in controls) were slightly higher in patients, but not significantly different. (nih.gov)
The relationship between kyn/trp and neopterin concentrations indicates that cellular immune activation rather than tumor-mediated IDO-activity is responsible (228 words). (nih.gov)
Les concentrations sériques de sCD40L circulant et d'interleukine 10 circulante ont été analysées à l'aide de la méthode immuno-enzymatique chez 30 patients positifs pour le VHC avec un CHC, chez 30 patients patients positifs pour le VHC avec une cirrhose du foie, et chez 30 volontaires d'âge correspondant en bonne santé avec des anticorps anti-VHC négatifs servant de groupe témoin. (who.int)
Decreases in serum prolactin concentrations in response to perioperative stress were significantly smaller in dogs exposed to sDAP, compared with findings in dogs exposed to the sham treatment. (avma.org)
This study aims at assessing how recombinant human growth hormone treatment of children and young people suffering from isolated growth hormone deficiency affects some selected parameters of the immune system: a percentage of lymphocytes, granulocytes, monocytes, concentrations of A, G, and M immunoglobulins, a percentage of T lymphocytes divided into subpopulations CD4 and CD8, a percentage of NK and B lymphocytes, and phagocytic activity of granulocytes and monocytes. (nel.edu)
Concentrations of A, G and M immunoglobulins in blood serum were assessed by means of immunoturbidimetric method using COBAS (manufactured by Roche). (nel.edu)
Although mean concentrations of IgM and IgA after 6 months of treatment with rhGH significantly decreased in comparison with those determined prior to treatment, they still remained within the baseline norm. (nel.edu)

During exposure to 200 µM, H2O2 female cardiomyocytes produced significantly fewer ROS and had a higher intracellular Ca2+ concentration compared to male cardiomyocytes in control and methionine-fed conditions. (bvsalud.org)
Sera concentration of circulating sCD40L and IL-10 were assayed using ELISA in 30 HCV-positive patients with HCC, 30 HCV-positive patients with liver cirrhosis and 30 age-matched healthy volunteers with negative anti-HCV-Ab as a control group. (who.int)
Results -Behavioral response variables and serum prolactin concentration were influenced by sDAP exposure. (avma.org)
The effective concentration of clofazimine against SARS-CoV-2 in vitro (half-maximal effective concentration (EC 50 ) of 0.31 μM in Vero E6 cells) is clinically achievable with a single dose of 200 mg d −1 (peak serum concentration ( C max ) of 0.86 μM) 17 . (nature.com)
Growth hormone treatment of children with isolated growth hormone deficiency does not significantly affect the activity of the immune system expressed by the phagocytic activity of monocytes, the percentage of B, T and NK lymphocytes and IgG concentration in blood serum. (nel.edu)

Antimalarial treatment is shown to be effective in decreasing splenomegaly, correcting anemia and lymphocytosis, and decreasing serum IgM in patients with HMS. (medscape.com)
In order to determine the positive cut off level of serum MUC5AC Ab, a ROC (receiving operating characterizing) curve was constructed between the normal and pathologic (polyps and colorectal carcinoma patients) groups. (medscape.com)
Patients with villous adenoma didn't have MUC5AC Ab in sera and MUC5AC expression in polyp specimen. (medscape.com)
Having MUC5AC expression at polyp specimens cause antibody formation against MUC5AC antigen at patients sera in the same time period. (medscape.com)
Regarding the Th17 response, patients with pAPS and HC showed a significantly lower frequency of circulating Th17 cells than SLE. (frontiersin.org)
pAPS and SLE patients had higher serum IL-6 levels than HC but there was not difference between both disease groups. (frontiersin.org)
Multiple logistics regression analysis suggested that male, race, lower SaO2/FIO2, higher serum potassium, lower serum albumin, and number of cardiovascular comorbidities were highly associated with the occurrence of cardiovascular events in COVID-19 patients. (nih.gov)
GC patients with differential serum high-density lipoprotein (HDL) or low-density lipoprotein (LDL) cholesterol levels were collected. (biomedcentral.com)
Cell dynamics in the immune response were weaker in patients with low lipoprotein cholesterol. (biomedcentral.com)
With the availability of novel therapeutics, such as immunotherapy, the outcomes of cancer patients have been improved significantly in recent years. (biomedcentral.com)
Studies support the notion that Omicron results in milder infections and less severe disease outcome 23 , however health systems face consequences due to high patient numbers resulting from high transmissibility and immune escape leading to infections in vaccinated and recovered patients. (researchsquare.com)
CUVITRU is an Immune Globulin Subcutaneous (Human), 20% solution indicated as replacement therapy for primary humoral immunodeficiency (PI) in adult and pediatric patients two years of age and older. (nih.gov)
In this study, we investigated the serum β -endorphin level in patients with AR and in healthy controls and evaluated the associations between the serum β -endorphin level and RQLQ scores as well as total IgE grade in the symptomatic stage in AR patients. (hindawi.com)
Patients with AR were selected according to the diagnostic criteria proposed by ARIA (symptoms, positive skin prick test, and positive serum-specific IgE) and were in the age range of 18-65 years [ 8 ]. (hindawi.com)
Serum samples were collected from all patients and healthy volunteers between 8 AM and 10 AM and stored at −80°C within 1 h until the assay for IgE and β -endorphin levels. (hindawi.com)
We analyzed the binding of the Omicron RBD to the human angiotensin-converting enzyme-2 receptor (ACE2) and the ability of human sera from COVID-19 patients or vaccinees in comparison to Wuhan, Beta, or Delta RBD variants. (nih.gov)
Similarly, sera from 27 COVID-19 patients, 81 vaccinated individuals, and 34 booster recipients were titrated by ELISA on RBDs from the original Wuhan strain, Beta, Delta, and Omicron VOCs. (nih.gov)
In this study the relationship between tryptophan degradation and immune activation was examined in 20 patients with gynecological cancer. (nih.gov)
beta 2-microglobulin, neopterin, tryptophan, and kynurenine levels were assayed in stored sera from asymptomatic, human T-cell leukemia virus type I (HTL V-I)-seronegative (HTLV-I-) and HTLV-I-seropositive (HTLV-I+) individuals, and ATL and HAM/TSP patients previously enrolled in seroepidemiological studies in Jamaica. (aacrjournals.org)
Mean levels of beta 2-microglobulin, neopterin, and kynurenine were significantly elevated among ATL patients compared to the other study groups. (aacrjournals.org)
Mean tryptophan levels were significantly lower among ATL and HAM/TSP patients than HTLV-I- and HTLV-I+ groups. (aacrjournals.org)
This study demonstrates a differential pattern of biomarkers of immune activation among ATL and HAM/TSP patients compared to HTLV-I- and HTLV-I+ individuals. (aacrjournals.org)
Serum sCD40L had higher diagnostic value in HCC patients compared with serum AFP. (who.int)
Assessment of serum IL-10 levels in HCV patients may provide a possible predictive marker for disease progression. (who.int)
Immune signatures for different stages of patients with HCC were systematically profiled and statistically compared. (bmj.com)
Furthermore, the dynamic changes of peripheral immune compositions for both first-line and second-line patients with HCC after anti-PD-1 monotherapy were also evaluated and systematically compared. (bmj.com)
We also revealed the treatment stage-specific immune signatures from peripheral blood and their dynamical changing patterns, all of which were integrated to achieve early discrimination of patients with non-durable benefit for both first-line and second-line anti-PD-1 monotherapies. (bmj.com)
Conclusions Our newly identified single-cell peripheral immune signatures provide promising non-invasive biomarkers for early detection of HCC and early assessment for anti-PD-1 immunotherapy efficacy in patients with advanced HCC. (bmj.com)
More significantly, LRRK2 expression in B cells was positively correlated with system lupus erythematosus disease activity index (SLEDAI), an indicator for disease severity, and serum IgG levels in SLE patients. (biomedcentral.com)
Despite considerable immune system variation among individual patients, the diagnostic absolute monocyte (AMC) and absolute lymphocyte (ALC) counts can reproducibly separate DLBCL patients with different outcomes. (confex.com)
20 cytokines were measured in duplicate in serum samples from 34 DLBCL patients with known outcome and 11 health donors using the mesoscale discovery (MSD) electrochemiluminescence platform. (confex.com)
In this cross-sectional study , authors studied hospital workers and a control group to assess antibody response to inactivated COVID-19 vaccine in patients with immune-mediated disease. (indianactsi.org)
In conclusion, a large majority of patients with immune modulated disease and immunocompetent controls developed a significant humoral response when the second vaccine was received. (indianactsi.org)
In two pilot studies, it was reported that platelet activation markers, such as P-selectin, CD62 and CD11b expression, were significantly higher in ITP patients ( 5 , 6 ). (frontiersin.org)
None of the patients exhibited any clinical symptoms of immune disorders. (nel.edu)

No difference in serum-circulating immune complexes was detected between the two groups. (karger.com)
The result is anemia, deposition of large immune complexes in Kupffer cells in the liver and spleen, reticuloendothelial cell hyperplasia, and hepatosplenomegaly. (medscape.com)
Lipid A is the toxic component of LPS and serves as the microbe-specific molecular signal that binds to the surface receptor complexes of immune cells, which comprise Toll-like receptor 4 (TLR4) and myeloid differentiation factor 2 (MD2) ( 14 , 15 ). (spandidos-publications.com)

even in mice with minor and heavy tumor load, administration of ESCs could generate effective antitumor immunity, which obviously improved the immune dysfunction and inhibit tumor growth [ 13 ]. (medsci.org)
Low serum lipoprotein cholesterol caused adverse effects on antitumor immunity in GC. (biomedcentral.com)

Serum cholesterol and triglyceride levels were significantly lower in colchicine-treated rats than in controls. (karger.com)
Article summary: Massage on healthy adults provided significant improvements in mood, immune function and serum cholesterol levels, according to recent research. (massagemag.com)
Blood and saliva samples were also taken in order to analyze cell levels associated with stress and immune function, as well as serum cholesterol. (massagemag.com)
Massage therapy also modulates immune function, induces hemodilution and decreases serum cholesterol. (massagemag.com)
Cholesterol is crucial for tumor immune microenvironment (TIME) remodeling. (biomedcentral.com)
Serum lipoprotein cholesterol is closely associated with gastric cancer (GC) progression, but whether it affects TIME remodeling is unknown. (biomedcentral.com)

Mice that were fed GE peas engineered with a gene from a bean demon-strated an immune response, including inflammation of the lungs and increased serum antibody levels. (hawaiiseed.org)
High levels of serum lipopolysaccharide (LPS), a potent endotoxin produced by Gram-negative bacteria, have been associated with pathological processes, including diabetes, the progression of kidney disease, obesity and inflammation ( 9 , 10 ). (spandidos-publications.com)
TGFβ1 knockout mice die from multifocal inflammation and autoimmune disorders in internal organs, suggesting its immune suppressive effect in these organs [ 3 , 4 ]. (ijbs.com)

Plasma levels of interleukin 10 (IL-10) and interferon gamma (IFNγ) are significantly increased. (medscape.com)
Serum samples were assayed by ELISA for LPS, C‑reactive protein (CRP), tumor necrosis factor‑α (TNFα), interleukin‑6 (IL6) and endothelin‑1. (spandidos-publications.com)

In addition to monitoring lack of reduction in viral load, serum levels of IP-10 and IL-10 expression during acute HCV infection may be useful biomarkers to predict the progress to chronic HCV. (nih.gov)
The obvious stage-dependent, inverted serum HHV-8 immunoreactivity facilitates a concept of viral immune-segregation YL-109 during KS advancement. (skinmicrobiomecongressca.com)

0.05).The piglets fed 10 and 15% fermented soybean meal showed the greatest growth improvement with higher levels of serum alkaline phosphatase and total serum proteins. (biomedcentral.com)

In a study of M2e-carrier conjugate vaccines, serum and supply. (cdc.gov)
Anania C, Olivero F, Spagnolo A, Chiesa C, Pacifico L. Immune response to vaccines in children with celiac disease. (wjgnet.com)

Thus, aPL have also emerged as triggers of innate immune inflammatory pathways in APS, through the activation of toll like receptors (TLR) ( 4 ). (frontiersin.org)
The Role Of Host Inflammatory Immune Response On Tissue. (bartleby.com)
Therefore the aim of this review is to discuss the role of host inflammatory immune response in tissue destruction seen in periodontal disease. (bartleby.com)
This arm of immune system involves oral epithelia which perform the barrier function and vascular and cellular elements which establish and propagate the inflammatory response. (bartleby.com)
Merin, 2015) This periodontal disease of inflammatory origin is thought to be the result of host immune response against bacterial colonies in the subgingival plaque. (bartleby.com)
Acute disseminated encephalomyelitis (ADEM) is an immune-mediated inflammatory demyelinating condition that predominately affects the white matter of the brain and spinal cord. (medscape.com)

MUC5AC antibody positive individuals were significantly higher in colorectal carcinoma 60% than in healthy controls 27.3% (p = 0.019). (medscape.com)
Proliferative response to lectins was significantly higher in the groups fed the high-vit E diets. (nih.gov)
The expression of IL-12 and TNF-α was significantly higher in the low vit-E groups, but not IL-1, IL-2, IFN-γ, IL-4, IL-6, IL-10 and the hormones. (nih.gov)
After the 7-valent pneumococcal conjugate vaccine (PCV7), the prevalence of serotype 6B significantly decreased (p = 0.040), a pattern which continued in the higher-valent PCV period (PCV10, PCV13). (cdc.gov)
Serum urea nitrogen in the experimental group was significantly lower than control whereas serum IgG, IgM and IgA levels were all significantly higher. (biomedcentral.com)
After two doses, IgG levels remained significantly higher in women compared to men, while percent inhibition was similar among both genders. (indianactsi.org)
Two weeks post boost, neutralizing activity against the Alpha (B.1.1.7) and immune-evading Beta (B.1.351) variant was ∼4-fold higher than in individuals receiving homologous BNT162b2 vaccination. (unboundmedicine.com)

Several factors including age, gender, ethnicity, quality and quantity of vaccine antigen, doses, and route of administration can influence immune response to vaccination, although the main cause of variation in the responsiveness among vaccine recipients is host genetic variability. (wjgnet.com)

We analysed 39 soluble immune factors in serum samples from subjects with transfusion-transmitted HCV. (nih.gov)

Three weeks following pDNA immunization, serum Ara h2-specific IgG2a, IgG1, but not IgE, were increased significantly in a dose-dependent manner. (tmu.edu.tw)

Anaphylactic or severe systemic hypersensitivity reactions to subcutaneous administration of Immune Globulin (Human). (nih.gov)
The present study conducted analyses of serum chemistries, immune phenotyping, gene expression, and histology to evaluate the systemic toxicity of a sub-chronic 28-day dermal exposure of alternative PFAS (1.25-5% or 31.25-125 mg/kg/dose) in a murine model. (cdc.gov)
Celiac disease (CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. (wjgnet.com)

However, to date, most related studies have focused on the direct effect of lipids on tumor cells, but the relationship between serum lipids and nontumorous components in the tumor microenvironment, especially immune cells and structures, is ill defined. (biomedcentral.com)
Recently tryptophan degradation by tumor cells was proposed as strategy to escape immune response. (nih.gov)

The role of the immune response in the pathogenesis of antiphospholipid syndrome (APS) remains elusive. (frontiersin.org)
Previous exposure to a pathogen is not required for activation of innate immune response. (bartleby.com)
Vaccination as well as natural infection induce a humoral and cellular immune response 4 . (researchsquare.com)
The opioid peptide β -endorphin is one of the most important mediators of both the immune response [ 3 , 4 ] and mental state [ 5 , 6 ]. (hindawi.com)

The present study compared the effects of soybean meal fermented by three different probiotics organisms with non-fermented soybean meal on growth performance, serum parameters, immune chemistry and intestinal morphology in weaned piglets. (biomedcentral.com)

Differential patterns of serum biomarkers of immune activation in human T-cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis, and adult T-cell leukemia/lymphoma. (aacrjournals.org)
Biomarkers of immune activation may correlate with perturbations of immune function associated with these diseases. (aacrjournals.org)
We conducted a pilot cross-sectional study to assess four candidate biomarkers of immune activation. (aacrjournals.org)

Within Group II and III, MUC5AC expression in the pathology specimens did not correlate with serum MUC5AC antibody levels. (medscape.com)

Human immune senescence accompanies with the physical and physiological frailty. (oncotarget.com)

Residential exposure to air pollution (AP) has been shown to activate the immune system (IS). (nih.gov)
while in vivo, administration of ESCs in tumor-bearing mice could generate significant antitumor effects by indirectly activating the antitumor immune system. (medsci.org)
So far, it is not hard to conclude that ESCs have double hit against cancer: direct inhibition by antitumor factors and indirect suppression by activating the body immune system. (medsci.org)
Studies have suggested that infections, stress, or immune system changes may be involved. (nih.gov)
Further studies at the molecular level may highlight the specific mechanism by which tobacco can interact with cells of the immune system and its impact on periodontal disease process. (scirp.org)
In addition, Beta-glucan stimulates the skin's own immune system and increases the resistance of the skin by doing so. (janssen-cosmetics.rs)
There has been a plethora of evidence that the immune system is able to control tumor outgrowth and a number of strategies have been put forward to utilize this ability for immunotherapy. (mdpi.com)
A promising approach to engage effector cells of the immune system overcoming some of the escape mechanisms has been introduced more than two decades ago. (mdpi.com)
This suggests distinct patterns of immune system deregulation in DLBCL which may serve to guide prognosis and therapy. (confex.com)
Immunosenescence is described as a decline in the normal function of the immune system associated with physiologic aging, which leads to increased susceptibility to infection, cancer and autoimmune diseases in aged organisms, including humans [ 1 ]. (oncotarget.com)

To determine whether the effects of ω-3 lipids in autoimmune disease (AI) is linked to vit-E levels, weanling female MRL/ lpr ( lpr ) and congenic control MRL/+/+ (+/+) mice were fed semipurified diets containing 10% corn oil (CO), 10% fish oil (FO), at two levels of vit-E (75 IU or 500 IU/kg diet) for 4m and cellular immune functions were measured. (nih.gov)
In further experiments when mice were treated with methotrexate, ACE2 expression significantly decreased in the lung, intestinal epithelium, and in intestinal organoids. (indianactsi.org)
Heat- inactivated immune serum induced passive cutaneous anaphylaxis, suggesting that anaphylaxis in C3H mice was mediated by IgG1. (tmu.edu.tw)
Although IgG2a was increased significantly from week 2 in AKR/J mice and from week 4 in BALB/c mice and remained elevated for at least 6 wk, no IgG1 or IgE was detected. (tmu.edu.tw)

The researchers looked at peripheral blood mononuclear cells (PBMCs), a type of immune cell that is easy to isolate from blood samples. (nih.gov)
Cells from all 20 people with ME/CFS, in contrast, showed significantly greater electrical changes. (nih.gov)
The team also optimized the assay for potential diagnostic use by comparing immune cells taken from blood plasma, whole blood, and serum. (nih.gov)
We clearly see a difference in the way healthy and chronic fatigue syndrome immune cells process stress. (nih.gov)
PROBIOTICS Pro-Immune Serum stabilises the skin's immune cells, strengthens its microbiome and protects it against digital ageing. (janssen-cosmetics.rs)
The Ectoin® in the serum also supports the skin's own protective mechanisms by protecting the Langerhans cells responsible for the skin's defence mechanisms. (janssen-cosmetics.rs)
Propolis and these components exhibited immunomodulatory effects on a wide spectrum of immune cells, including cells of lymphoid or monocytic lineages, mediated by the extracellular signal-regulated kinase 2 and mitogen-activated protein-kinase signalling pathway and by eukaryotic transcription factors: nuclear factor of activated T cells and nuclear factor κB. (ijpsonline.com)
In a pattern identical to that of HIF-1 expression, the steady-state levels of MCL-1 were not significantly affected by I or I/R and MCL-1 co-localized with HIF-1α in Leydig cells. (biomedcentral.com)
Consistent with the reduction in IgG production, the percentages of germinal center B cells and plasma cells decreased significantly as well with LRRK2 deficiency. (biomedcentral.com)
Regulatory T cells (Treg) are CD4+ T cells with immune-suppressive function, which is defined by Foxp3 expression. (stanford.edu)
In addition to B cell dependent autoimmune mechanisms, it is well established that cellular immune pathophysiology of ITP is associated with several T-cell abnormalities, including uncontrolled activation of T helper cells, deficiency of T regulatory cells, and increase of CD8 + T cell targeting megakaryocytes, etc. ( 2 , 3 ). (frontiersin.org)
The Alpha, Beta, Delta, and Kappa variants of spike are potently neutralized by sera from all participants and reactive T cells recognize spike peptides of all tested variants. (unboundmedicine.com)

A monoclonal anti-Lrig1 antibody significantly improves the symptoms of experimental autoimmune encephalomyelitis. (stanford.edu)

these should include a negative antibody control (omission of primary antibody or non-immune serum) and use of negative tissue samples. (cdc.gov)

Immune thrombocytopenia (ITP) is characterized by low peripheral blood platelet count. (frontiersin.org)

In the study, 82 hospital workers with immune-mediated disease and 300 control members were evaluated, all subjects had a negative history of COVID-19. (indianactsi.org)

Adult T-cell leukemia/lymphoma (ATL) and human T-cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) are associated with differing patterns of immune dysfunction. (aacrjournals.org)

To determine whether gut microbiota, fatty metabolism and cytokines were associated with immune thrombocytopenia (ITP). (frontiersin.org)

Body composition analysis revealed that inulin significantly increased protein content and decreased lipid levels, especially in the T1 and T2 groups. (cmu.ac.th)

HHV-8 sero-detection technology continues to be PRKCG a developing region and brand-new assays like ELISAs might not yet have already been examined in the high-endemicity African sera when compared with IFA [4,10]. (skinmicrobiomecongressca.com)

Immune suppression or pathogenic strains are possible explanations. (vin.com)

History The HIV and Helps epidemic has significantly increased the regularity of different malignancies especially Kaposi's sarcoma (KS) and specific malignant lymphoma YL-109 (ML) that are from the book individual herpesvirus type 8 (HHV-8)/Kaposi's sarcoma-associated herpes simplex virus (KSHV) and also have turn into a main wellness concern in sub-Saharan Africa including Tanzania [1-3]. (skinmicrobiomecongressca.com)

Sera were obtained after at least 21 days following the second vaccination. (indianactsi.org)

In addition levels of serum IgG were significantly lower in smokers compared to non-smokers with chronic periodontitis and healthy controls (P (scirp.org)

Anatomy35

Organisms18

Diseases22

Chemicals and Drugs91

Analytical, Diagnostic and Therapeutic Techniques and Equipment44

Phenomena and Processes49

Information Science3

Health Care4

Antibodies12

Responses22

Cytokine7

Immunoglobulin3

Innate immune3

Autoantibody3

Antibody titers2

Statistically significant1

Urine2

Concentrations10

Concentration5

Patients35

Complexes3

Immunity2

Cholesterol6

Inflammation3

Interleukin2

Viral2

Proteins1

Vaccines2

Inflammatory6

Higher7

Antigen1

Soluble1

Immunization1

Systemic3

Tumor cells2

Response4

Parameters1

Biomarkers3

Correlate1

Accompanies1

System10

Mice4

Cells12

Symptoms1

Samples1

Peripheral blood1

Study1

Dysfunction1

Microbiota1

Lipid1

Detection1

Pathogenic1

Malignancies1

Vaccination1

Lower1