• We have previously shown that a single dose of ketamine, a glutamate N-methyl-d-aspartate (NMDA) receptor antagonist, is associated with a rapid reduction in depressive symptom severity and SI in patients with treatment-resistant depression. (nih.gov)
  • Secondary endpoints were the reduction in severity and frequency of gas-related symptoms as recorded by parents and/or children. (biomedcentral.com)
  • The current state of pharmacology research for CUD highlights the need to consider particular characteristics of patients, such as gender, impulsivity, and severity of cannabis use, when selecting a medication in the off-label treatment of CUD or cannabis withdrawal. (nature.com)
  • There was a positive correlation between anxiety states and traits with symptom severity and distress during conventional treatment intervals. (virginia.edu)
  • 0.001) between depression scores with symptom severity and distress during surgery, RT, and CT. (virginia.edu)
  • Although photosensitivity, a well-established side-effect of pirfenidone, was the major adverse event in this study, it was mild in severity in most of the patients. (ersjournals.com)
  • There was no increase in symptom severity due to therapy transfer. (hbz-nrw.de)
  • The researchers evaluated symptom severity and various biomarkers, including hand grip strength (HGS), cardiovascular function, and laboratory parameters. (meassociation.org.uk)
  • PCS-ME/CFS patients reported persistently high severity of most symptoms up to 20 months after infection, while patients with PCS showed overall health improvement. (meassociation.org.uk)
  • Previous studies have shown that psychoanalytic psychotherapies produce robust and enduring improvements in not only symptom severity but also personality organization in patients who have chronic depression and early life trauma, especially if therapy is delivered at a high weekly frequency. (biomedcentral.com)
  • A 2019 randomized, double-blind, placebo-controlled, multicenter trial involving 109 patients with celiac disease on a strict gluten-free diet found that a 6-week probiotic treatment used in the study was beneficial in improving the severity of IBS-type symptoms and is associated with a modification of gut microbiota, characterized by an increase of Bifidobacterium . (nih.gov)
  • A small significant effect was found in reduction in symptom severity: standard mean difference = -0.32, 95% CI = -0.56 to -0.08. (mcmaster.ca)
  • In addition, the depressive individuals' performances were compared according to the presence or absence of previous depressive episodes, psychopharmacological treatment and severity of symptoms. (bvsalud.org)
  • This co-occurrence might lead to an impairment of cognitive functions, worse response to antidepressant medications, and an increased risk of suicide in comparison to patients with PTSD alone. (frontiersin.org)
  • Meta-analysis data indicate that in as many as 52% patients with a posttraumatic stress disorder (PTSD), major depressive disorder (MDD) co-occurs, which might lead to an impairment of cognitive functions, worse response to antidepressant medications, and an increased risk of suicide in comparison to patients with PTSD alone ( 1 ). (frontiersin.org)
  • It was shown that approximately six percent of variance in dropout rates could be attributed to therapists, even when initial impairment was controlled for. (hbz-nrw.de)
  • Aim 1 will assess the effectiveness of TranS-C (combined Adapted and Standard), compared to UC-DT, on improvements in sleep and circadian problems, functional impairment, and psychiatric symptoms for Generation 2 patients. (biomedcentral.com)
  • No significant differences between augmentation with medication versus placebo were found in ratings of functional impairment and dropouts due to adverse events. (mcmaster.ca)
  • A novel intervention that uses goal setting to promote a more active lifestyle significantly slows cognitive and functional decline in older black patients with mild cognitive impairment (MCI), new research shows. (medscape.com)
  • Baseline data (patient characteristics, clinical status, generalized self-efficacy, expectations of future work ability) and treatment variables were used as independent variables in logistic regressions. (biomedcentral.com)
  • Limitations of the study are a drop-out rate of 39% and sociodemographic and clinical differences between both treatment groups. (urotoday.com)
  • As we have taken on more trainees in the department (this includes CAT practitioner trainees, junior psychiatrists and trainee clinical psychologists), the number of patients taken on for CAT has increased so that at any one time, around 40 patients are engaged in CAT. (me.uk)
  • METHODS: Drug-naïve patients with GAD, with or without comorbid depression and healthy controls underwent functional magnetic resonance imaging and clinical assessments at baseline and after treatment. (bvsalud.org)
  • The challenge is to identify those patients with the highest benefit/risk ratio in clinical practice. (ersjournals.com)
  • The secondary outcomes included the difference between groups at 16 weeks in a number of different scales including the Repetitive Behavior Scale-Revised, Spence Children's Anxiety Scale, Aberrant Behavior Checklist-Community Version, Clinical Global Impression Scale-Global Improvement and Efficacy Index, and Disruptiveness Assessment. (hcplive.com)
  • POEMs (patient-oriented evidence that matters) are provided by Essential Evidence Plus, a point-of-care clinical decision support system published by Wiley-Blackwell. (aafp.org)
  • In addition to the clinical predictors, findings from pretreatment resting-state functional MRI (fMRI) for 112 patients showed significant differences between those who did and those who did not achieve remission with CBT compared with antidepressant therapy, reported coauthor Boadie Dunlop, MD, of Emory University. (medscape.com)
  • One study on the validity of a diagnosis of early-onset schizophrenia in Denmark found a correspondence of 88.8%, comparing the diagnosis listed in the Denmark registry to a clinical diagnosis based on symptoms reported in patient records. (medscape.com)
  • In a clinical setting, differences between the cognitive disturbances in vascular dementia and Alzheimer disease are of limited value in distinguishing the 2 conditions. (medscape.com)
  • 9 10 Current guidelines for the management of irritable bowel syndrome in the United Kingdom recommend that the diagnosis should be made on clinical grounds alone, without the need for invasive investigations, unless alarm symptoms such as rectal bleeding or weight loss are present. (bmj.com)
  • A multicentre, double-blind, placebo-controlled, randomised phase III clinical trial was conducted in Japanese patients with well-defined IPF to determine the efficacy and safety of pirfenidone, a novel antifibrotic oral agent, over 52 weeks. (ersjournals.com)
  • Following an open-label phase II pioneer study 7 and an open-label 1-yr study in Japan 9 , a double-blind, placebo-controlled clinical trial of pirfenidone in Japanese patients with IPF demonstrated a lesser decline of vital capacity (VC) in patients receiving pirfenidone for 9 months 15 . (ersjournals.com)
  • These encouraging results, prompted us to undertake a phase III 1-yr clinical study to examine the therapeutic effects of pirfenidone on lung functional deterioration and disease progression in patients with IPF. (ersjournals.com)
  • Due to this result and the restricted generalization of clinical studies to clinical practice, a more patient-focused research strategy has emerged. (hbz-nrw.de)
  • Acupuncture was initially described as a successful treatment for certain overactive bladder symptoms in the 1980s ( 4 , 5 ), and, since then, a number of clinical trials on incontinence have been carried out ( 6 - 8 ). (spandidos-publications.com)
  • We included randomised clinical trials evaluating the outcome of a trauma-focused psychotherapy, cognitive behavioural therapy (CBT), prolonged exposure therapy (PE), cognitive processing therapy, eye movement desensitisation and reprocessing (EMDR), or narrative exposure therapy or stress management compared with treatment by sertraline, paroxetine, fluoxetine or venlafaxine, or combinations of these, to reduce PTSD symptoms in adults. (ugeskriftet.dk)
  • Eating disorder symptoms and clinical variables were assessed in 168 obese female patients with DSM-5 BED or subthreshold BED, referred to a 6-month outpatient CBT program in a pre-post measurement design. (biomedcentral.com)
  • Clinical guidelines issued in 2021 by the American College of Gastroenterology recommend against the use of probiotics for the treatment of global IBS symptoms. (nih.gov)
  • The abstract ' Clinical Development of Mannan conjugated birch pollen allergoids for the treatment of birch pollen allergic patients - from first-inhuman to approval in 3 studies . (touchimmunology.com)
  • Notwithstanding, non-signifi cant differences were observed during the secondary analysis in relation to the clinical variables. (bvsalud.org)
  • This trial aims to assess whether real-time collection and clinical feedback of patient treatment experiences can reduce patient symptom burden. (cdc.gov)
  • based on clinical criteria, it is diagnosed only when the patient is ≥ 16 years and ≥ 5 years older than the child who is the target of the fantasies or behaviors. (msdmanuals.com)
  • Clinical disease: physical signs and symptoms resulting from a sufficiently absorbed toxicant dose. (cdc.gov)
  • They identified a number of traits (e.g., exploration, reflection, support, warmth, confidence and attending to patient experience) which positively related to outcomes. (me.uk)
  • Childhood-onset schizophrenia is a severe form of psychotic disorder that occurs at age 12 years or younger and is often chronic and persistently debilitating, with worse outcomes than patients who have later onset of symptoms. (medscape.com)
  • They instead suggested a cut-off age of 14.7 years of age based on higher levels of positive symptoms and poorer psychosocial functioning under this cut-off and better outcomes over this cut-off. (medscape.com)
  • I blog about therapist variables leading to poor outcomes, aspects of the therapeutic relationship and outcomes, and psychological therapies and patient quality of life. (uottawa.ca)
  • Improving patient outcomes and reducing dropout rates by the use of psychometric feedback seems to be a promising path. (hbz-nrw.de)
  • The primary outcome (depression) and psychological secondary outcomes (anxiety symptoms and wellbeing) will be measured using validated instruments. (biomedcentral.com)
  • I'm sure he had a statistician determine how many subjects would be needed for appropriate power to detect a significant difference in the primary outcomes. (hormonesdemystified.com)
  • The present study will evaluate implementation and effectiveness outcomes of an EBPT for sleep and circadian dysfunction-the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C)-delivered to CMHC patients with serious mental illness by Generation 2 providers (i.e., trained and supervised within CMHCs via TTT). (biomedcentral.com)
  • Specifically, we will investigate whether adapting TranS-C to fit CMHC contexts improves Generation 2 (a) patient outcomes and (b) providers' perceptions of fit. (biomedcentral.com)
  • Aim 3 will evaluate whether Generation 2 providers' perceived fit mediates the relation between TranS-C treatment condition and patient outcomes. (biomedcentral.com)
  • Exploratory analyses will (1) evaluate whether the effectiveness of TranS-C for patient outcomes is moderated by generation, (2) compare Adapted and Standard TranS-C on patient perceptions of credibility/improvement and PhenX Toolkit outcomes (e.g., substance use, suicidality), and (3) evaluate other possible moderators. (biomedcentral.com)
  • Pulmonary Resection and Intensive Rehabilitation study (PuReAIR) will contribute significantly in investigating the effects of perioperative rehabilitation on exercise capacity, symptoms, lung function and long-term outcomes in surgically treated lung cancer patients. (physiospot.com)
  • CS and celecoxib showed a greater significant reduction in pain and LI than placebo. (bmj.com)
  • In the intention-to-treat (ITT) population, pain reduction in VAS at day 182 in the CS group (−42.6 mm) and in celecoxib group (−39.5 mm) was significantly greater than the placebo group (−33.3 mm) (p=0.001 for CS and p=0.009 for celecoxib), while no difference observed between CS and celecoxib. (bmj.com)
  • Similar trend for the LI, as reduction in this metric in the CS group (−4.7) and celecoxib group (−4.6) was significantly greater than the placebo group (−3.7) (p=0.023 for CS and p=0.015 for celecoxib), no difference was observed between CS and celecoxib. (bmj.com)
  • More recently, two RCTs (IMPACT and TRIBUTE) compared triple therapy versus LABA/long-acting muscarinic antagonist (LAMA) combinations in patients at high ECOPD risk, and also showed a 15-25% reduction in ECOPD rates ( figure 1 ) [ 17 , 18 ]. (ersjournals.com)
  • HbA1c reduction was significant within face-to-face (−0.46, P =02) but not within virtual world (−0.31, P =.19), although there were no significant between group differences in HbA1c ( P =.52). (researchprotocols.org)
  • Type 2 diabetes is a complex chronic illness requiring continuing medical care and, ideally, patient adherence to numerous behavioral recommendations for self-management (ie, prescriptions for dietary change, physical activity, weight reduction, blood glucose self-monitoring, smoking cessation, and medication intake) [ 1 ] with the goal of achieving glucose control and preventing diabetes complications. (researchprotocols.org)
  • The reduction of gas production can be considered as a valuable target in controlling symptoms. (biomedcentral.com)
  • To the best of our knowledge, this is the first report on the reduction of PTSD symptoms after performing an insulin tolerance test. (frontiersin.org)
  • Reduction of PTSD symptoms in PTSD and MDD comorbidity has been noticed after a hypoglycemic episode. (frontiersin.org)
  • The current study aimed to examine whether treatment self-efficacy (self-efficacy regarding the mastery of obstacles during treatment) in guided Internet-delivered therapy for anxiety disorders in adults could be a predictor of lower dropout rates and greater symptom reduction. (frontiersin.org)
  • Symptom reduction was measured at 10 measurement points, including a 6-month follow-up. (frontiersin.org)
  • The results showed that high treatment self-efficacy was a predictor of both lower dropout rates and greater symptom reduction. (frontiersin.org)
  • Significant interaction effects between time and treatment self-efficacy were found for several of the nine modules that constitutes the treatment program, suggesting that treatment self-efficacy could be a moderator of symptom reduction. (frontiersin.org)
  • The results suggest that measuring treatment self-efficacy may be a valuable tool to identify patients at risk of dropping out, and that treatment self-efficacy could be a predictor and moderator of symptom reduction in guided Internet-delivered therapy. (frontiersin.org)
  • The elderly often present attributable to a reduction in mental, cognitive and phys- with somatic or non-specific symptoms rather than the ical abilities, increased probability of death among their typical symptoms of depression, such as low energy, friends or loved ones, retirement and loss of communi- fatigue, reduction in physical movements and cognitive cation with people. (who.int)
  • This article will introduce an important research development to provide an evidence-based approach to current treatment methods and practices for young patients. (lww.com)
  • Methods-- We implemented a pragmatic cluster randomized controlled trial to test the effectiveness of an automated interactive voice response tool designed to provide physicians with real-time patient-reported data about responses to newly prescribed diabetic peripheral neuropathy medicines. (cdc.gov)
  • Traditional Treatment methods used by psychiatric patients seeking treatment from The University Psychiatric Unit, National Hospital Sri Lanka. (who.int)
  • Compared to virtual world, face-to-face was marginally superior for reducing depression symptoms ( P =.051). (researchprotocols.org)
  • Further analyses from the Prediction of Remission to Individual and Combined Treatments (PREDICT) randomized controlled trial, which included 344 treatment-naive patients with MDD, as well as findings from the 1000 patient‒strong international Study to Predict Optimized Treatment in Depression (iSPOT-D), were presented here at the Anxiety and Depression Association of America (ADAA) 2018 Conference. (medscape.com)
  • The differences were seen in three regions in the subcallosal cingulate cortex (SCC) known to be implicated in depression ― the left frontal operculum, the left ventromedial prefrontal cortex, and the periaqueductal gray/dorsal raphe. (medscape.com)
  • For stress-related symptoms, Self-rating Depression Scale, State-Trait Anxiety Inventory-trait, and Pittsburgh Sleep Quality Index (PSQI) scores decreased after L-theanine administration ( p = 0.019, 0.006, and 0.013, respectively). (mdpi.com)
  • In addition to the five symptom domain areas identified in the diagnostic criteria, the assessment of cognition, depression, and mania symptom domains is vital for making critically important distinctions between schizophrenia and other psychotic disorders. (medscape.com)
  • This study shows that the effects of psychotherapy when initiated in the acute phase of major depression (at the outset of symptoms) are enduring over a longer time frame. (uottawa.ca)
  • Several types of psychotherapy are effective to treat depression, and there appears to be very little difference among the treatments in term of their effectiveness. (uottawa.ca)
  • In this meta-analysis, Cuijpers and colleagues examined studies in which a psychotherapy for depression was compared to a control condition in which patients did not receive an active treatment. (uottawa.ca)
  • Beck's Depression Inventory (BDI) and symptom checklist were assessed at baseline, after surgery, before, during, and after RT and six cycles of CT. (virginia.edu)
  • Its study is of great importance for contemporary psychotherapy, as it may lead to discovery of neurobiological mechanisms that predict and mediate lasting changes in psychotherapy, particularly in severely mentally ill patients, such as those with chronic depression. (biomedcentral.com)
  • Patients with chronic major depression and a history of early life trauma will be recruited, assessed, and treated across 3 international sites: Germany, Switzerland, and the United States. (biomedcentral.com)
  • These findings could help to personalize care for patients who have chronic depression patients and early life trauma , and they will provide new therapeutic targets for both psychological and biological treatments for major depressive illness. (biomedcentral.com)
  • EMDR therapy has a positive impact on intrusive imagery (such as nightmares and flashbacks), numbing, and hyperarousal symptoms of PTSD, as well as on associated grief and depression. (emdrhap.org)
  • The presence of depressive symptoms was determined using the geriatric depression scale: a score 5 indicated depressive symptoms. (who.int)
  • There were no statistically significant differences between Group 1 and 2 in any baseline characteristics. (sigvaris.com)
  • While the results of the trial, in aggregate, showed no statistically significant differences among the groups in symptom scores, 45% of people preferred DTE, 32% preferred T4/T3, and 23% preferred T4 alone. (hormonesdemystified.com)
  • Conclusion A 800 mg/day pharmaceutical-grade CS is superior to placebo and similar to celecoxib in reducing pain and improving function over 6 months in symptomatic knee osteoarthritis (OA) patients. (bmj.com)
  • The investigators found that the fluoxetine group had a mean score of 9.02 points, while the placebo group had a mean score of 10.89 points, which was deemed statistically significant. (hcplive.com)
  • These researchers recruited 80 patients with chronic rhinosinusitis (two or more symptoms, including mucopurulent drainage, nasal obstruction, facial pain, and decreased sense of smell for at least 12 weeks) to be randomized, allocation concealment unknown, to receive treatment using a large-volume saline sinus irrigation with placebo or budesonide, 1 mg once daily, for 30 days. (aafp.org)
  • Patients received a single infusion of ketamine or midazolam (as an active placebo) in addition to standard of care. (nih.gov)
  • Fifty-two pediatric patients (32 female, age range 4-17) with chronic or recurrent gas-related symptoms were randomized to receive placebo (n = 25) or α-galactosidase (n = 27). (biomedcentral.com)
  • This randomized, placebo-controlled, crossover, and double-blind trial aimed to examine the possible effects of four weeks L-theanine administration on stress-related symptoms and cognitive functions in healthy adults. (mdpi.com)
  • A random effects model was used to pool data on symptoms, and the effect of therapy compared with placebo or no treatment was reported as the relative risk (95% confidence interval) of symptoms persisting. (bmj.com)
  • Results 12 studies compared fibre with placebo or no treatment in 591 patients (relative risk of persistent symptoms 0.87, 95% confidence interval 0.76 to 1.00). (bmj.com)
  • Twenty two trials compared antispasmodics with placebo in 1778 patients (0.68, 0.57 to 0.81). (bmj.com)
  • Four trials compared peppermint oil with placebo in 392 patients (0.43, 0.32 to 0.59). (bmj.com)
  • or placebo groups in the ratio 2:1:2), 267 patients were evaluated for the efficacy of pirfenidone. (ersjournals.com)
  • A 2020 systematic review and meta-analysis of 35 randomized controlled trials involving 3,452 participants found that compared to placebo, probiotics improved persistent symptoms and showed beneficial effects on global IBS symptoms, including abdominal pain, bloating, and flatulence. (nih.gov)
  • Seven of the studies included in the review reported that probiotics significantly improved IBS symptoms compared with placebo, whereas the other four studies did not report any significant improvement in IBS symptoms after taking probiotics. (nih.gov)
  • We have conducted this study in approximately 300 patients and can see significant effects when comparing the actively treated group with placebo group. (touchimmunology.com)
  • The difference is 35%, which is unusual for just five injections or treatment visits, but not only the symptoms and the medication need is reduced, but we also see a significant improvement in the quality of life of patients treated with this active component in comparison to placebo. (touchimmunology.com)
  • Recent research on the multimodal treatment of eating disorders in child and adolescent psychiatry has yielded a significant increase in randomized controlled trials and systematic reviews. (lww.com)
  • Anorexia nervosa and atypical anorexia nervosa are by far the most prevalent eating disorders among patients admitted to child and adolescent psychiatric (CAP) treatment or to paediatric units with a CAP liaison service, whereas patients with bulimia nervosa and avoidant/restrictive food intake disorder (ARFID) are seen comparatively less often. (lww.com)
  • Differences between before and after treatment were analysed using paired t tests for continuous variables and marginal homogeneity test for categorical variables. (biomedcentral.com)
  • Assessing work ability and expectations of RTW at the beginning of treatment is recommended to identify patients at risk of long-term sick leave. (biomedcentral.com)
  • It is essential that treatment focus not only on symptom-relief, but also on improving work ability and expectations of RTW. (biomedcentral.com)
  • Three months after prostatectomy, there were no significant differences between both treatment groups regarding urinary continence. (urotoday.com)
  • In the Liaison Psychiatry department of Addenbrooke's Hospital in Cambridge, patients referred for psychological treatment are offered either Cognitive Behaviour Therapy (CBT) or Cognitive Analytic Therapy (CAT). (me.uk)
  • In addition, some patients are travelling a long way for treatment because Addenbrooke's hospital is a specialist centre for many disorders and attracts complicated patients from many outlying areas, some as much as 62 miles away. (me.uk)
  • Thus, this report aimed to identify whether age, gender, medically unexplained symptoms, distance from home to service, and who the client was seen by (i.e., trainee or qualified staff member) were significantly related to whether or not the client completed a course of CAT treatment. (me.uk)
  • The goal of this research is to diagnose Alzheimer's patients for timely treatment. (bvsalud.org)
  • All these factors must be carefully considered and balanced in any individual COPD patient before adding ICS to her/his maintenance bronchodilator treatment. (ersjournals.com)
  • Interpretation is limited by the high dropout rate, null findings of prespecified analyses that accounted for potentially confounding factors and baseline imbalances, and CIs for the treatment effect that included the minimal clinically important difference. (hcplive.com)
  • The treatment effect was no longer significant at the end of the 7-day assessment period. (nih.gov)
  • To evaluate the efficacy and tolerability of α-galactosidase in the treatment of gas-related symptoms in pediatric patients. (biomedcentral.com)
  • Although larger and longer trials are needed to confirm this result, α-galactosidase seems to be a safe, well tolerated and effective treatment for gas-related symptoms in the pediatric population. (biomedcentral.com)
  • There were no significant differences in recurrence according to treatment groups. (medscape.com)
  • Results showed that after switching treatment, 48.2% of the patients experienced remission. (medscape.com)
  • Even patient preference for treatment modality was found to be associated with treatment completion, as reported in findings published i n 2017. (medscape.com)
  • Specifically, whereas the receipt of a patient's preferred modality (CBT or antidepressant medication) did not predict remission at 12 weeks ( P = .31), those patients who did not receive their preferred treatment modality were significantly more likely to drop out of the trial ( P = .01), usually within the first few weeks of treatment, said Dunlop. (medscape.com)
  • study reveal that hydrocortisone augmentation during prolonged exposure therapy may result in a greater retention in the treatment group, thereby improving PTSD symptom response ( 7 ). (frontiersin.org)
  • MDD, 296.22 [ Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision ( DSM-IV-TR )] was diagnosed, and the patient received escitalopram 20 mg/d, with no improvement after 5 weeks' treatment. (frontiersin.org)
  • Most currently available interventions have similar overall efficacy, and treatment choices should reflect the situation of individual patients. (psychiatrist.com)
  • The minimum duration of therapy considered was one week, and studies had to report either a global assessment of cure or improvement in symptoms, or cure of or improvement in abdominal pain, after treatment. (bmj.com)
  • Negative effects refer to the deterioration or worsening of depressive symptoms during treatment. (uottawa.ca)
  • In such studies, one might expect the control condition to represent what would happen in terms of symptoms if the patient received no treatment. (uottawa.ca)
  • However, not all patients experience improvement, and although predictors of treatment outcome have been identified, few are consistent over time and across studies. (frontiersin.org)
  • Three of nine modules in the panic disorder treatment and six of nine in the social anxiety disorder treatment showed significant interaction effects. (frontiersin.org)
  • This calls for ways in which more patients can receive treatment for their disorder. (frontiersin.org)
  • Conclusion: The results suggest that yoga can be used for managing treatment-related symptoms and anxiety in breast cancer outpatients. (virginia.edu)
  • CONCLUSION: The results suggest possible antidepressant effects with yoga intervention in breast cancer patients undergoing conventional treatment. (virginia.edu)
  • 1 - 3 Treatment options are often limited and patients suffer increasing exercise limitation as their disease progresses. (bmj.com)
  • However, not every patient profits from psychotherapy and some patients even deteriorate in treatment. (hbz-nrw.de)
  • The results therefore indicated that not only patient characteristics or treatment progress affected the use of feedback. (hbz-nrw.de)
  • Study II (Chapter 6) picked up on the idea of analyzing systematic differences in therapists and applied it to the criterion of premature treatment termination (dropout). (hbz-nrw.de)
  • Data from 124 patients who agreed to and experienced a transfer during their treatment were analyzed. (hbz-nrw.de)
  • however, at present, it is also studied and used for the treatment of broader symptoms, such as urinary incontinence. (spandidos-publications.com)
  • The aim of this study was to investigate the effect of psychotherapy treatment alone and combined with medications, as proposed in the current guidelines, to reduce PTSD symptoms. (ugeskriftet.dk)
  • Furthermore, we aimed to describe dropout differences between these two treatment regimens. (ugeskriftet.dk)
  • An "abnormal" level in Methadone maintenance treatment (MMT) patients was defined as one standard deviation above or below the mean for controls (2.39-6.39 nmol/L was the normal range). (recoveryanswers.org)
  • Results showed that Methadone maintenance treatment (MMT) participants had significantly more perceived stress and PTSD symptoms. (recoveryanswers.org)
  • Regarding differences between individuals still in MMT at 6 months and those who were no longer in treatment (drop-out, death, jail, asked to leave program), non-completers had similar self-report measures of stress, but greater likelihood of abnormal cortisol (91% vs. 51%).They also evidenced greater withdrawal symptoms, more opioid use, poorer medication compliance, and less group therapy attendance. (recoveryanswers.org)
  • In analyses predicting days in methadone maintenance treatment (MMT), treatment discontinuation, and time to discontinuation by 6 months, also controlling for confounding variables (demographics and substance use variables), abnormal cortisol level was the best, and often only, significant predictor. (recoveryanswers.org)
  • A significantly greater proportion of patients with normal cortisol relative to abnormal cortisol remained in Methadone maintenance treatment (MMT) across the 6-month follow-up. (recoveryanswers.org)
  • Study findings suggest that a thorough assessment of Methadone maintenance treatment (MMT) patients' stress levels when they are initially admitted to treatment may help identify individuals at particularly high risk of dropping out of treatment prematurely. (recoveryanswers.org)
  • The sample was small (58 patients) and from a single treatment program. (recoveryanswers.org)
  • It is unclear whether these results generalize to other programs and populations of Methadone maintenance treatment (MMT) patients. (recoveryanswers.org)
  • Treatment outcome groups showed significant overall differences on the DPI Resistance and Dependence scales and the aggregated 'neurotic' scale. (biomedcentral.com)
  • A 2021 systematic review and meta-analysis of 9 randomized controlled trials involving 651 pediatric patients found that probiotics significantly reduced the abdominal pain score, increased the rate of abdominal pain treatment success and abdominal pain relief, and reduced the frequency of abdominal pain. (nih.gov)
  • Despite the fact that a number of therapeutic interventions exist to alleviate symptoms - ranging from pharmaceutical products to natural therapies - women remain reluctant to take medications during pregnancy, and a safe, effective and acceptable treatment for NVP is still to be found. (sigvaris.com)
  • CMHCs are cluster-randomized by county to Adapted TranS-C or Standard TranS-C. Within each CMHC, patients are randomized to immediate TranS-C or usual care followed by delayed treatment with TranS-C (UC-DT). (biomedcentral.com)
  • Practice Guideline for the Treatment of Patients with Acute Stress Disorder and Posttraumatic Stress Disorder. (emdrhap.org)
  • The authors describe the study protocol for the open-label randomized controlled trial we are conducting on patients affected by primary lung cancer (stages I-II) eligible for surgical treatment. (physiospot.com)
  • Patient compliance and treatment-related side effects are also collected. (physiospot.com)
  • BACKGROUND: A systematic review and meta-analysis was conducted to explore the efficacy of medication augmentation strategies compared to control treatments in patients who have had a partial or no response to initial treatment for generalized anxiety disorder, social anxiety disorder, and panic disorder. (mcmaster.ca)
  • Background-- Challenges to effective pharmacologic management of symptomatic diabetic peripheral neuropathy include the limited effectiveness of available medicines, frequent side effects, and the need for ongoing symptom assessment and treatment titration for maximal effectiveness. (cdc.gov)
  • Telephone Study, a randomized trial designed to improve medication treatment, titration and quality of life among patients with symptomatic diabetic peripheral neuropathy. (cdc.gov)
  • These calls provide patients with the opportunity to report on symptoms, side effects, self-titration of medication dose and overall satisfaction with treatment. (cdc.gov)
  • This study investigated changes in work participation and mental health, and predictors of RTW among patients being treated for common mental disorders (CMDs). (biomedcentral.com)
  • Existence of diabetes mellitus (regardless of type), duration of untreated mental illness and lack of patient therapeutic education were negative predictors of (unfavourable) outcome. (who.int)
  • Various predictors of alliance and symptom development after transfer were investigated. (hbz-nrw.de)
  • We conducted a randomized, controlled trial of ketamine in patients with mood and anxiety spectrum disorders who presented with clinically significant SI (n = 24). (nih.gov)
  • EDE-Q global scores, self-reported binge eating frequency and BMI significantly decreased during CBT, where 44.3% of patients showed clinically significant change in EDE-Q global score. (biomedcentral.com)
  • Furthermore, multiple logistic regression analysis, controlling for mild to moderate depressive disorder and TCI harm avoidance showed that 'neurotic' personality functioning was a significant negative predictor of clinically significant change. (biomedcentral.com)
  • Moreover, 'neurotic' personality functioning is a predictor of clinically significant change. (biomedcentral.com)
  • Approximately half of all patients with posttraumatic stress disorder (PTSD) also suffer from major depressive disorder (MDD). (frontiersin.org)
  • A patient with MDD with the co-occurrence of PTSD was admitted to the Department of Endocrinology with suspicion of adrenal insufficiency. (frontiersin.org)
  • After inducing a hypoglycemic episode with intravenous short-acting insulin, PTSD symptoms were reduced. (frontiersin.org)
  • Neuroimaging studies reveal differences between people with PTSD and MDD and those with PTSD alone ( 2 - 4 ). (frontiersin.org)
  • Here we describe a case of a female patient with MDD with the co-occurrence of PTSD diagnosed in the Department of Endocrinology, where she was admitted with suspicion of adrenal insufficiency. (frontiersin.org)
  • Two systematic reviews found insufficient evidence to determine whether trauma-focused psychotherapy is more effective than SSRI in reducing PTSD symptoms [5, 10]. (ugeskriftet.dk)
  • This "A" category is described as "A strong recommendation that clinicians provide the intervention to eligible patients. (emdrhap.org)
  • Ten of 29 patients remitted from MDD completed two-year follow-up assessment. (lu.se)
  • The intervention was well tolerated and no dropouts occurred during the primary 7-day assessment period. (nih.gov)
  • In addition, people who present with an injury or a fall may not be able to recall symptoms before the fall, meaning that that the presence of orthostatic hypotension might be missed unless actively sought as part of a structured assessment. (nice.org.uk)
  • Assessment of personality functioning and personality traits could support indication for more specified or augmented care, tailored towards the patients' individual strengths and vulnerabilities. (biomedcentral.com)
  • Maladaptive ('neurotic') personality functioning is significantly associated with a less favorable outcome after CBT in patients with binge eating. (biomedcentral.com)
  • The current evidence base has suggested that the therapeutic alliance is the most consistent predictor of positive outcome in psychotherapy, and significant research has been conducted to better understand this relationship. (me.uk)
  • In this cohort of primary care patients with predominantly subacute or chronic ACJ pain of non-traumatic onset, traditional ACJ tests were of limited diagnostic value. (biomedcentral.com)
  • The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the management of patients with chronic obstructive pulmonary disease (COPD) is much debated. (ersjournals.com)
  • In patients with chronic rhinosinusitis, does the addition of budesonide (Rhinocort) to a saline irrigation solution result in further improvement in symptoms? (aafp.org)
  • This study showed that patients with chronic rhinosinusitis who continue to use a saline nasal wash (NeilMed) will often experience an improvement in symptoms that can be clinically meaningful, but the addition of the corticosteroid budesonide has yet to show an extra benefit. (aafp.org)
  • Irritable bowel syndrome is a chronic relapsing and remitting condition, 8 9 and a significant proportion of patients will consult their general practitioner with symptoms. (bmj.com)
  • Although exercise training effectively improves exercise capacity and health related quality of life in patients with chronic obstructive pulmonary disease (COPD), 4 its role in patients with ILD is unclear. (bmj.com)
  • Current guidelines for exercise prescription in chronic lung disease are based on evidence from studies of patients with COPD 7 where respiratory mechanics and peripheral muscle dysfunction are major limitations to exercise capacity. (bmj.com)
  • Sexually transmitted infections may be present without symptoms or with symptoms that are mild and transient, but they may have severe long-term consequences such as infertility, ectopic pregnancy, chronic illness and premature death. (who.int)
  • My complaint about this criticism is that it gets me nowhere, with respect to deciding what to do with the symptomatic, T4-treated hypothyroid patient sitting in my office, who has otherwise "perfect" lab results. (hormonesdemystified.com)
  • Conclusions-- Innovative strategies are needed to guide improvements in healthcare delivery for patients with symptomatic diabetic peripheral neuropathy. (cdc.gov)
  • Pre-post differences within and between intervention groups were assessed using t tests and chi-square tests (two-sided and intention-to-treat analyses for all comparisons). (researchprotocols.org)
  • Three meta-analyses concluded that manualized therapies were superior, four meta-analyses did not find differences, and one observed non-manualized treatments to be superior. (uottawa.ca)
  • In addition, authors conducted dozens of statistical analyses without controlling for multiple tests inflating the overall type I error rate (i.e., increasing the probability of finding a significant result due to chance). (recoveryanswers.org)
  • The first internet-based intervention trial protocol using a mobile application to improve depressive symptoms among migrant workers (overseas Filipino workers). (biomedcentral.com)
  • There is a need to screen and treat depressive symptoms among older Palestinian adults to prevent their progression to severe mental health problems. (who.int)
  • α-galactosidase has been shown to reduce gas production and related symptoms in adults. (biomedcentral.com)
  • A considerable percentage of older Palestinian adults had depressive symptoms. (who.int)
  • A 2019 systematic review of 11 studies evaluating the effects of probiotics on IBS symptoms found mixed results. (nih.gov)
  • In patients with a history of autism spectrum disorder or a communication disorder of childhood onset, the additional diagnosis of schizophrenia is made only if prominent delusions or hallucinations, in addition to the other required symptoms or schizophrenia are also present for at least 1 month (or less if successfully treated). (medscape.com)
  • The validity of a diagnosis of childhood-onset schizophrenia has been a point of concern for some, due to difficulty in differentiating pediatric patients' reports of visual hallucinations from imaginary figures (which may be developmentally normal). (medscape.com)
  • Lower hand grip strength (HGS) at onset correlated with symptom persistence and burden, particularly in patients with PCS-ME/CFS. (meassociation.org.uk)
  • The study included 106 patients who have moderate to severe fatigue and exertion intolerance at three time points following Covid-19 infection (3-8 (baseline), 9-16, and 17-20 months). (meassociation.org.uk)
  • This study aims to evaluate the value of baseline radiographs in COVID-19-infected patients. (bvsalud.org)
  • Method: This is a retrospective study of COVID-19 patients with RT-PCR confirmation who were admitted to Eka Kotebe General Hospital and had baseline chest x-ray between April and May 2020. (bvsalud.org)
  • Baseline chest x-ray of all patients who have confirmed COVID-19 infection was reviewed and analyzed. (bvsalud.org)
  • Conclusion: Even if chest radiographs are important in the workup of patients with COVID-19 infection, the use of baseline radiographs in COVID-19 infection should not be a routine practice. (bvsalud.org)
  • However, these statistical numbers do not reflect the overall economic and emotional burden to society and families, although in this age group, caregivers are still of significant relevance [2▪] . (lww.com)
  • This was also reported in a study conducted in Macao, which showed that common mental disorders are likely to contribute to a significant burden to this population [ 7 ]. (biomedcentral.com)
  • These findings provide evidence of a high prevalence of diabetes in psychiatric patients and that having diabetes has an adverse effect on outcome of psychiatric illness. (who.int)
  • Computerized working memory training (CWMT) shows promising results, but findings are inconclusive regarding which symptoms improve following this intervention, and its long-term effects. (lu.se)
  • No significant differences between completers and drop-outs were found, however, attrition effects cannot be ruled out and demand characteristics could influence findings. (lu.se)
  • The current findings provide initial support for the safety and tolerability of ketamine as an intervention for SI in patients who are at elevated risk for suicidal behavior. (nih.gov)
  • The dosage was also decreased for any patient who suffered from a significant adverse effect. (hcplive.com)
  • Important unmet needs exist for treatments (1) that work rapidly, with (2) broad spectrum benefits, (3) that can improve rates of remission and well-being, (4) are devoid of risk for withdrawal symptoms, and (5) have few if any adverse interactions with other drugs. (psychiatrist.com)
  • Nonetheless, it appears that there was no statistically significant difference among the three groups with respect to the primary outcome of symptom scores. (hormonesdemystified.com)
  • In DSM-5 BED is characterized by recurrent, weekly episodes of uncontrollable overeating and significant distress, without compensatory behaviors as present in bulimia nervosa [ 2 ]. (biomedcentral.com)
  • Further analysis investigated whether improvements in symptoms, work ability, expectations of future work ability and generalized self-efficacy were associated with RTW. (biomedcentral.com)
  • Number of individuals with full work participation increased, and there were improvements in symptoms, work ability and generalized self-efficacy. (biomedcentral.com)
  • The results from the selected RCTs failed to demonstrate any statistically significant improvements in urinary incontinence, although acupuncture or acupressure did exhibit favorable effects on overactive bladder symptoms and quality of life, in comparison with other conventional therapies. (spandidos-publications.com)
  • 11 12 As a result general practitioners are increasingly responsible for the initial management of patients with irritable bowel syndrome and are expected to refer only a minority to secondary care. (bmj.com)
  • Some researchers estimated that 5% to 10% of patients deteriorate during therapy. (uottawa.ca)
  • Despite the fairly reasonably sized study, the researchers did also experience high group drop out levels, with 19 patients dropping out (12 with PCS and 7 with PCS-ME/CFS), and another 46 did not complete the follow-ups. (meassociation.org.uk)
  • We also decided to look at age, gender and whether the patient had medically unexplained symptoms (MUS) to investigate whether those factors had any impact on rates of successful therapeutic outcome. (me.uk)
  • Therefore, agents that decrease the amount of gas in the intestine may represent an effective therapeutic strategy for the management of gas-related symptoms when their cause depends, at least in part, on gas hyper-production. (biomedcentral.com)
  • On average, there seemed to be no difficulties establishing a good therapeutic alliance with the new therapist, although differences between patients were observed. (hbz-nrw.de)
  • This network meta-analysis included 81 trials representing over 13,000 patient participants. (uottawa.ca)
  • We predicted a dropout rate of 35% and accordingly mailed invitations to 2,061 potential participants. (cdc.gov)
  • Participants first completed a phone interview about COVID-19 symptoms within the previous 15 days. (cdc.gov)
  • The liaison psychiatrists were interested in whether the distance patients had to travel was affecting drop-out rates from CAT, in which case it may be better to recommend that these patients are treated nearer to their home (although, in practice, CAT is often not available to patients with these kinds of medical problems). (me.uk)
  • This squares with both selected studies that have already been done on this topic - including Dr. Hoang's similar 2013 study - as well as with the experience of many patients across the internet and a smaller number of patients in my practice. (hormonesdemystified.com)
  • Here, we review the evidence available for ("friend") and against ("foe") ICS use in COPD and propose that ICS, added to one or two long-acting bronchodilators (never as stand-alone medication), can benefit some (but not all) COPD patients. (ersjournals.com)
  • Patients assigned to physicians in the intervention group receive three brief interactive calls every 2 months after a medication is prescribed to alleviate diabetic peripheral neuropathy symptoms. (cdc.gov)
  • This study reports results from a longitudinal open-label two-year follow-up pilot-study of self-reported cognitive residual symptoms following 25 sessions (40 min), five times a week of a digitally delivered CWMT intervention. (lu.se)
  • The former showed moderate non-significant associations to improvement in CWMT both post-intervention (r = 0.575) and at two-year follow-up (r = 0.308). (lu.se)
  • The study stoppage criteria was progressive disease rendering the patient bedridden or any physical musculoskeletal injury resulting from intervention or less than 60% attendance to yoga intervention. (virginia.edu)
  • Exercise training improves exercise capacity and symptoms in patients with ILD, but these benefits are not sustained 6 months following intervention. (bmj.com)
  • We plan to Author Manuscript compare changes in self-reported quality of life between the intervention group and patients in the control group who receive three non-interactive automated educational phone calls. (cdc.gov)
  • The main difference between the two groups was that the active intervention included goal-setting and the controls did not. (medscape.com)
  • There were no differences in longer term effectiveness among the different types of psychotherapy. (uottawa.ca)
  • This dissertation aims to better understand therapist differences in the context of patient-focused research and the impact of therapists on psychotherapy. (hbz-nrw.de)
  • In their trial of CAT for personality disorders, Clarke et all reported that 10 out of 50 patients allocated to CAT discontinued therapy before completion of 24 sessions, giving a drop out rate of 20% (Clarke S., 2013). (me.uk)
  • This small study, with a significant drop-out rate, did not have the power to find a difference if one exists. (aafp.org)
  • The American Academy of Neurology no longer recommends syphilis screening in the routine evaluation of dementia if patients come from geographic regions with a very low base rate of syphilis. (medscape.com)
  • Expecting a 10% dropout rate, assuming α of 5% and power of 80%, they planned to enrol 140 patients to demonstrate a statistically significant difference of 25 m at Six-Minute Walk Test. (physiospot.com)
  • Despite evidence-based treatments a considerable number of BED patients fail to recover. (biomedcentral.com)
  • The study examined and compared continence rates in prostate cancer patients who had undergone either open retropubic prostatectomy (RRPE) or endoscopic extraperitoneal radical prostatectomy (EERPE). (urotoday.com)
  • Later RCTs of ICS/long-acting β 2 -agonist (LABA) combinations generally recruited patients with ≥1 ECOPD in the previous year, and showed that ICS/LABA combinations reduce ECOPD rates by approximately 25-35% compared with LABA monotherapy ( figure 1 ) [ 3 - 14 ]. (ersjournals.com)
  • Recent analysis of recurrence rates in 94 patients who experienced remission after receiving 12 weeks of either CBT or pharmacotherapy showed that 15.5% experienced a recurrence during the maintenance period, study coauthor W. Edward Craighead, PhD, Department of Psychiatry and Behavioral Sciences at Emory University, Atlanta, Georgia, reported. (medscape.com)
  • To answer the question whether therapist effects occur in terms of patients' dropout rates, data from 707 patients treated by 66 therapists were investigated. (hbz-nrw.de)
  • The analyzed data comes from an open effectiveness study including 575 patients receiving guided Internet-delivered therapy for panic disorder or social anxiety disorder. (frontiersin.org)
  • Assessments included Speitberger's State Trait Anxiety Inventory and symptom checklist. (virginia.edu)
  • and the secondary objectives are to explore the preliminary effectiveness of the SbS-F to decrease participant-reported anxiety symptoms and improve wellbeing, and to evaluate the potential for SbS-F implementation in real-world settings. (biomedcentral.com)
  • The study was a prospective pre-post study of 164 patients treated at an RTW outpatient clinic for CMDs. (biomedcentral.com)
  • One study of 88 patients found the age cut-off of 12 years old to lack utility. (medscape.com)
  • One study showed manuals were superior, three showed no difference, and two studies showed that non-manualized therapies were more effective. (uottawa.ca)
  • Another study in patients with type 2 diabetes compared apple cider vinegar with water. (elixirnews.com)
  • Three different studies are included, which focus on different aspects within the field: Study I (Chapter 5) investigated how therapists use psychometric feedback in their work with patients and how much therapists differ in their usage. (hbz-nrw.de)
  • comparing these to the subset of patients who also met the diagnostic criteria for ME/CFS (referred to as PCS-ME/CFS ), i.e. this study looked at PCS vs PCS-ME/CFS. (meassociation.org.uk)
  • The PCS-ME/CFS were diagnosed based on the Canadian Consensus Criteria (CCC) which included 55 patients out of the 106 in the total study cohort. (meassociation.org.uk)
  • The aim of the study was to explore whether personality functioning or personality traits are associated with Cognitive Behavioral Therapy (CBT) outcome in obese female patients with BED or subthreshold BED. (biomedcentral.com)
  • The results which we show here are impressive also when compared with other developments that are currently undergoing and what we can show here from an efficacy point of view in the mid-scale phase 3 study, not one of these big mega studies with more than 1,000 patients. (touchimmunology.com)
  • The aim of this study ( 1 ) was to evaluate the effect of medical compression stockings (MCS) on symptoms of nausea, vomiting and dizziness between 8 and 16 weeks of pregnancy, and their impact on QoL factors. (sigvaris.com)
  • Stage I wa a hospital based study conducted in the Kurunegala district and comprised of a work sampling study, survey of records and a cross sectional survey of random sample of 1305 patients attending hospital dental clinics in the district. (who.int)
  • As a result, the study of genetic markers in nutritional research has been on the rise to help understand the inherent differences between individuals. (lu.se)
  • Result: The study included 355 patients, 224 (63.1%) were male and 131 (36.9%) were female. (bvsalud.org)
  • ABSTRACT We evaluated the prevalence of diabetes comorbidity in Greek psychiatric patients, differences between type 1 and type 2 diabetics and the outcome of psychiatric disorder. (who.int)
  • The digestive enzyme decreased the number of days with moderate to severe bloating (p = 0.03) and the proportion of patients with flatulence ( p = 0.02). (biomedcentral.com)
  • Sexual offenses against children constitute a significant proportion of reported criminal sexual acts. (msdmanuals.com)
  • Indeed, more than 20% of the general population suffers from abdominal pain or discomfort and 16% from bloating or distension [ 2 ] with no evidence of any inflammatory, anatomic, metabolic or neoplastic process that explains the subject's symptoms. (biomedcentral.com)
  • Altered gastrointestinal motility may contribute to the change in bowel habit reported by some patients, 5 and a combination of smooth muscle spasm, visceral hypersensitivity, and abnormalities of central pain processing may explain the abdominal pain that is an essential part of the symptom complex. (bmj.com)
  • however, no significant differences were found in abdominal pain scores, bloating scores, or quality-of-life scores. (nih.gov)
  • But, increasing the daily intake of probiotics was not found to decrease abdominal pain further and, thus, no significant correlation between abdominal pain and the amount of probiotics ingested was found. (nih.gov)
  • DSM-5 diagnostic criteria for schizophrenia requires at least two of the following five symptoms to be present for a month. (medscape.com)
  • MCS could therefore be a non-pharmaceutical instrument to alleviate nausea and vomiting symptoms during early pregnancy. (sigvaris.com)
  • This One-Pager reviews the effectiveness of medical compression stockings (MCS) against various signs and symptoms, throughout pregnancy & beyond. (sigvaris.com)
  • Wearing compression stockings in early pregnancy improves not only nausea and vomiting-associated symptoms, but also QoL factors such as dizziness, leg pain and physical/physiological limitations. (sigvaris.com)
  • Intestinal gas-related symptoms are generally not considered to be a severe medical problem but can negatively affect quality of life, even in pediatric age [ 3 ]. (biomedcentral.com)
  • Symptoms were severe enough to have a considerable impact on lifestyle. (who.int)
  • Three hundred fifty prostate cancer patients (166 EERPE, 184 RRPE) were asked to self-assess symptoms associated with urinary incontinence (UI) 1 day before and 3 months after prostatectomy. (urotoday.com)
  • Patients who underwent nerve-sparing prostatectomy and patients younger than 65 years had a better chance of regaining urinary continence earlier. (urotoday.com)
  • By three months, the principal symptoms had resolved for 97 of the women while there was significant improvement in urinary function, psychological health, activities of daily living, lifestyle activities and sexual enjoyment. (who.int)
  • Cannabis, also known as marijuana, is used to treat some symptoms related to cancer. (mskcc.org)
  • The hypoglycemic effect of berberine was first reported in 1988 when it was used to treat diarrhea in diabetic patients [ 22 ]. (hindawi.com)
  • Treat patients with risk factors for cerebrovascular disease. (medscape.com)
  • Age was categorised into 6 decades, and the number, and percentage of dropouts was calculated as illustrated in table 1. (me.uk)
  • The incidence of diabetes mellitus in psychiatric patients has been found to be 2 to 8 times higher than in the general population [1-3]. (who.int)
  • No significant differences were found for abdominal spasms and abdominal distension. (biomedcentral.com)
  • Significant overall differences were found between groups on TCI Harm avoidance, although post hoc t-tests were non-significant. (biomedcentral.com)
  • Various antispasmodics were studied, but otilonium (four trials, 435 patients, relative risk of persistent symptoms 0.55, 0.31 to 0.97) and hyoscine (three trials, 426 patients, 0.63, 0.51 to 0.78) showed consistent evidence of efficacy. (bmj.com)
  • The average decrease in scores was 20.7 points in the treated group and 13.6 points in the control group, which was not statistically significant. (aafp.org)
  • Self-reported subjective cognitive difficulties (subjective deficits) and rumination are central residual cognitive symptoms following major depressive disorder (MDD). (lu.se)
  • In PREDICT, patients with MDD were randomly assigned to receive either 12 weeks of cognitive-behavioral therapy (CBT) or 12 weeks of therapy with antidepressant therapy with the selective serotonin reuptake inhibitor (SSRI) escitalopram ( Lexapro , Forest Labs) or the serotonin and norepinephrine reuptake inhibitor (SNRI) duloxetine ( Cymbalta , Lilly). (medscape.com)