• Proteins
  • We hypothesize that this novel family of proteins function as molecular scaffolds to mediate the assembly/stability of signal transduction components in a variety of signal-response systems (i.e., not limited to phototropism). (bio.net)
  • GTPase-activating proteins or GTPase-accelerating proteins (GAPs) are a family of regulatory proteins whose members can bind to activated G proteins and stimulate their GTPase activity, with the result of terminating the signaling event. (wikipedia.org)
  • By doing so, they accelerate the G protein's built-in timer, which inactivates the G proteins more quickly, and along with the inactivation of GEFs, this keeps the G protein signal off. (wikipedia.org)
  • protein
  • In this sense, GAPs function is opposite to that of guanine nucleotide exchange factors (GEFs), which serve to enhance G protein signaling. (wikipedia.org)
  • transcription
  • Postdoc position - signal transduction & transcription Applications are invited for postdoctoral positions in a newly established research group at the Ludwig Institute for Cancer Research (LICR) in Uppsala, Sweden. (bio.net)
  • Therapy
  • The Division of Signal Transduction Therapy or DSTT is an organization managed by the University of Dundee, the Medical Research Council, and the pharmaceutical companies AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Merck Serono, Janssen Pharmaceutica, and Pfizer. (wikipedia.org)
  • environmental
  • Responses of cells to environmental signals, toxins and stressors have profound implications for diverse aspects of human health and disease including development, cystic fibrosis, diabetes, asthma, heart, autoimmune diseases and cancer. (novapublishers.com)
  • approaches
  • Carrying on the high standards of the much-acclaimed first edition, highly experienced investigators have extensively updated Signal Transduction Protocols with many of the new approaches that have been transforming the field. (springer.com)