Signal TransductionTransduction, GeneticMolecular Sequence DataProtein Sorting SignalsAmino Acid SequenceCell LinePhosphorylationCells, CulturedBase SequenceRNA, MessengerProtein BindingInterferon Type IRecombinant ProteinsMutationTransfectionInterleukin-1Receptors, InterleukinDNA-Binding ProteinsBinding SitesEnzyme ActivationInterleukin-2Gene Expression RegulationInterleukin-6Protein Structure, TertiaryTranscription FactorsCollagen Type IProtein-Tyrosine KinasesRecombinant Fusion ProteinsModels, BiologicalKineticsMembrane ProteinsTumor Cells, CulturedGene ExpressionSequence Homology, Amino AcidCell DivisionMice, Inbred C57BLTyrosineMitogen-Activated Protein KinasesT-LymphocytesCytokinesBacterial ProteinsCalciumBlotting, WesternTranscription, GeneticProteinsReceptors, Cell SurfaceProtein-Serine-Threonine KinasesCarrier ProteinsAdaptor Proteins, Signal TransducingTime FactorsPromoter Regions, GeneticCell MembraneProtein KinasesEnzyme InhibitorsCloning, MolecularProtein Kinase CGenetic VectorsTumor Necrosis Factor-alphaPhosphoproteinsCell DifferentiationTrans-ActivatorsReverse Transcriptase Polymerase Chain ReactionInterleukin-4Lymphocyte ActivationApoptosisProto-Oncogene ProteinsLigandsNF-kappa BDNAMice, KnockoutIntracellular Signaling Peptides and ProteinsDose-Response Relationship, DrugInterleukin-8Models, MolecularInterferon-gammaPhenotypeCOS CellsAntigens, CDGTP-Binding ProteinsDNA, ComplementaryEscherichia coliMice, Inbred BALB CMAP Kinase Signaling SystemCell NucleusFibroblastsPhosphatidylinositol 3-KinasesInterleukinsCalcium-Calmodulin-Dependent Protein KinasesType C PhospholipasesCyclic AMPReceptors, Interleukin-1Mutagenesis, Site-DirectedCell Line, TumorPlasmidsReceptors, Interleukin-2Flow CytometrySequence AlignmentSTAT3 Transcription FactorPeptidesCytoplasm