Motor NeuronsSignal TransductionNeuronsMotor Neuron DiseaseCell SurvivalSurvival of Motor Neuron 1 ProteinApoptosisNeurons, AfferentCells, CulturedSurvival of Motor Neuron 2 ProteinMotor CortexSurvival RateTransduction, GeneticEvoked Potentials, MotorSpinal CordAmyotrophic Lateral SclerosisMolecular Sequence DataPhosphorylationTime FactorsCell LineProtein Sorting SignalsMutationCaspasesMuscular Atrophy, SpinalMotor ActivityAmino Acid SequenceCaspase 3Apoptosis Regulatory ProteinsEnzyme ActivationNerve Tissue ProteinsAxonsImmunohistochemistryRNA, MessengerCell Line, TumorModels, BiologicalMice, Inbred C57BLTransfectionSMN Complex ProteinsMice, TransgenicBlotting, WesternAction PotentialsProto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsGene Expression RegulationEnzyme InhibitorsBase SequenceTranscription FactorsTumor Cells, CulturedMice, KnockoutCell DifferentiationDNA-Binding ProteinsProto-Oncogene ProteinsDose-Response Relationship, DrugMembrane ProteinsIn Situ Nick-End LabelingDisease-Free SurvivalCalciumDisease Models, AnimalRats, Sprague-DawleyGene ExpressionDNA FragmentationCell ProliferationCell DeathCell DivisionNerve DegenerationSurvivalGreen Fluorescent ProteinsMolecular Motor ProteinsElectric StimulationBrainMitochondriabcl-2-Associated X ProteinSynapsesProtein-Serine-Threonine KinasesRecombinant Fusion ProteinsMitogen-Activated Protein KinasesProtein BindingElectrophysiologyReverse Transcriptase Polymerase Chain ReactionCarrier ProteinsAnimals, NewbornSurvival AnalysisGanglia, InvertebrateSuperoxide DismutaseRecombinant ProteinsProtein Structure, TertiaryNeuromuscular DiseasesPhenotypeProteinsSynaptic TransmissionProtein-Tyrosine KinasesMembrane PotentialsMovementIntracellular Signaling Peptides and ProteinsAnimals, Genetically ModifiedGene Expression Regulation, DevelopmentalInterneuronsX-Linked Inhibitor of Apoptosis ProteinGenetic VectorsSensory Receptor Cells