• Immunohistochemical and immunoelectron study of major histocompatibility complex class-II antigen in canine cutaneous histiocytoma: its relation to tumor regression. (illumina.com)
  • However, in both humans and horses, these tumors are potentially immunogenic, i.e., capable of producing an immune response, and can serve as a model for the investigation of the immune mechanisms involved in tumor regression induced by therapeutic molecules. (eurekalert.org)
  • The researchers also deployed next-generation sequencing and analysis based on bioinformatics and systems biology to map the initial mechanisms of the response triggered by Amblyomin-X, which culminated in tumor regression. (eurekalert.org)
  • These findings described the first steps in the activation of a defense response that culminated in tumor regression, pointing to potential candidate targets for adjuvant therapies against tumors. (eurekalert.org)
  • Keratoacanthomas (KAs) are benign cutaneous neoplasms that occur in elderly patients who are frequently exposed to the sun. (medscape.com)
  • 6] Case reports have described AN associated with hematologic malignancies, including acute myeloid leukemia, and even benign gastrointestinal neoplasms. (medscape.com)
  • It is unclear whether clear cell acanthoma represents a benign neoplasm or a reactive inflammatory dermatosis. (statpearls.com)
  • An erythematous area was noted, and the lesion was mistaken for a malignant neoplasm. (medscape.com)
  • These workers are also at increased risk for cutaneous neoplasms, with an odds ratio (OR) of 3.67 for cSCCs, 3.32 for basal cell carcinoma (BCC), and 1.97 for melanoma. (medicalacademic.co.za)
  • Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases. (kreftfri.no)
  • Preclinical data demonstrate that multiple immunomodulators synergize with radiotherapy to cause the regression of irradiated tumors and, less often, nonirradiated metastases. (aacrjournals.org)
  • Spontaneous regression of primary malignant melanomas with regional metastases. (revistaendocrino.org)
  • Spontaneous regression of pulmonary metastases from testicular embryonal carcinoma. (greenmedinfo.com)
  • The spontaneous involution and eventual disappearance of these lesions, within months, characterizes the self-healing nature of KAs. (medscape.com)
  • KAs are well-contained lesions, but case reports have shown perineural and vascular invasion. (medscape.com)
  • Physical examination showed asymptomatic purple maculopapular lesions, with a symmetrical serpiginous linear pattern along both the lower limbs including the soles (Fig. 1 ). (biomedcentral.com)
  • These lesions are often discovered asymptomatically but may present fever, chest pain, dyspnea, or hemoptysis-these latter 2 symptoms may be more frequently encountered in airway lesions.The imaging findings of thoracic IMT primarily consist of a solitary pulmonary nodule or mass, which may show calcification-this appearance, in a young patient, while not pathognomonic, suggests IMT.The margins of thoracic IMTs may be smoothly circumscribed or lobulated or poorly defined. (elsevierpure.com)
  • These lesions often show intense contrast enhancement and may even be associated with aberrant systemic arterial supply, resembling pulmonary sequestration.The treatment of choice for thoracic IMT is limited surgical resection, with corticosteroid therapy or radiation reserved for unresectable patients or patients with inadequate surgical margins. (elsevierpure.com)
  • The argument that this represents a reactive inflammatory dermatosis is supported by studies that used immunohistochemical staining to show that these lesions express cytokeratins similar to those seen in other inflammatory dermatoses, such as psoriasis. (statpearls.com)
  • Spontaneous regression: In 20% to 23% of patients with a single lesion, and in up to 7.2% of patients with field cancerisation (presence of multiple AKs surrounded by an area of photodamaged skin) lesions may disappear spontaneously. (medicalacademic.co.za)
  • Computed tomography (CT), performed in June 20XX, showed newly emerging lesions, such as multiple nodules in both lungs, a right axillary tumor, and the already-known hepatic lesion (multiple enlarged hepatic hemangiomas). (springeropen.com)
  • EMC shows the smallest morphological variation between the tumors among all myxoid soft tissue neoplasms. (wikipedia.org)
  • Experiments were conducted by scientists affiliated with the Center of Excellence in New Target Discovery, a research center supported by FAPESP, involving five animals with spontaneous skin tumors. (eurekalert.org)
  • Equine melanomas are spontaneous tumors. (eurekalert.org)
  • In the first phase of the study, spontaneous tumors in five horses were treated for 30 days with intratumoral injections of Amblyomin-X. The treatment took place at the Butantan Institute's farm in Araçariguama, state of São Paulo. (eurekalert.org)
  • IMTs have been reported in numerous organ systems, but most commonly are encountered within the thorax, usually the lung or tracheobronchial tree, and uncommonly the mediastinum.IMTs show variable biological behavior, ranging from spontaneous regression to locally aggressive behavior, including recurrence after resection and even distant metastatic disease. (elsevierpure.com)
  • A case of spontaneous regression of metastatic testicular teratoma. (greenmedinfo.com)
  • Spontaneous regression of metastatic testicular carcinoma in a patient with bilateral sequential testicular tumor. (greenmedinfo.com)
  • Extraskeletal myxoid chondrosarcoma (EMC) is a rare low-grade malignant mesenchymal neoplasm of the soft tissues, that differs from other sarcomas by unique histology and characteristic chromosomal translocations. (wikipedia.org)
  • Weiss and Enzinger first reported epithelioid hemangioendothelioma (EHE) in 1982 as a rare vascular endothelial neoplasm arising in soft tissues [ 1 ]. (springeropen.com)
  • For instance, people viewing substances are generally most interested in viewing diseases that these substances have shown to have positive influences. (greenmedinfo.com)
  • This is followed by coverage of neoplasms in the more traditional categories of epithelial, mesenchymal, and other categories. (abdominalkey.com)
  • Epithelioid hemangioendothelioma (EHE) is a rare and slow-growing malignant vascular neoplasm composed of epithelioid endothelial cells within a distinctive myxohyaline stroma. (springeropen.com)
  • ABSTRACT: Deep penetrating nevi (DPN), particularly those showing combined features, or combined deep penetrating nevi (CDPN), may show histopathological resemblance to blue nevus (BN) and melanoma. (bvsalud.org)
  • Thereafter, some patients progressing on ipilimumab showed systemic responses only upon receiving radiation to one lesion, confirming clinically the proimmunogenic effects of radiation. (aacrjournals.org)
  • The pigmented clear cell acanthoma or melanoacanthoma histologically, as well as clinically varies from a typical clear cell acanthoma in that it shows a higher number of melanocytes and increased levels of melanin within the lesion. (statpearls.com)
  • However, Del Rosso et al showed that imiquimod is also safe and effective to treat larger lesion sizes. (medicalacademic.co.za)
  • Although the classic presentation of BIA-ALCL is known as late persistent seroma, an atypical manifestation such as spontaneous resorption may occur, as in the current case. (e-aaps.org)
  • In secondary echinococcosis, larval tissue spreads from the primary site and new cysts develop after spontaneous or trauma-induced cyst rupture or after release of viable parasite material during invasive treatment procedures. (cdc.gov)
  • Ultrasound showed a large left sided ovarian cyst with equivocal blood flow on color doppler. (heraldopenaccess.us)
  • The cyst showed no signs of regression and in fact increased marginally in size at 3 months follow up. (heraldopenaccess.us)
  • Multiple KAs should raise suspicion of Muir-Torre syndrome, a genodermatosis with a defect in the MSH mismatch repair gene that is associated with sebaceous neoplasms and gastrointestinal cancers. (medscape.com)
  • The effect of primaquine daily dose on gastrointestinal symptoms on days 5-7 was assessed by modified Poisson regression (tolerability analysis). (cdc.gov)
  • The etiology of DC remains enigmatic and DC is distinct from hidradenitis suppurativa, which is shown by their varied responses to therapies and their histologic differences. (escholarship.org)
  • These are therapies with endorsement for the management of solid neoplasms. (revistaendocrino.org)
  • The clinical manifestations of endocrinopathies associated with immunotherapy should be recognized, considering the increasing use of these therapies for different neoplasms. (revistaendocrino.org)
  • Immune checkpoint inhibitors are drugs currently used for different types of neoplasms, these drugs are associated in a significant percentage with endocrinopathies, however, finding the simultaneous involvement of two endocrine glands is unusual, being this the second reported case in the literature with hypophysitis and adrenalitis. (revistaendocrino.org)
  • 0 download) in the acute 60 neoplasm password Facts of anaesthetic realities. (rollwithitmn.org)
  • c) High-power view of the same sympathetic ganglion showing degenerating neurons (single arrowheads) and mononuclear infiltrates (double arrowhead). (medscape.com)
  • Recent studies of endometrial cancers arising in US women, however, show the prevalence of such mutations to be significantly lower (11% versus 31%) than in Japan . (medmuv.com)
  • DC is likely a reaction pattern, as is shown by its varied therapeutic successes and failures. (escholarship.org)
  • Our results show that HES1 , regulated by NOTCH2 , as an indicator of sensitivity to imatinib, and an important therapeutic consideration for desmoid tumor. (e-crt.org)
  • Recent statistics demonstrate that EMC shows a higher incidence of local recurrence, metastasis and patient mortality and therefore are classified as mean-grade malignancies. (wikipedia.org)
  • We assessed the effects of total dose and duration of primaquine regimens on the rate of first P vivax recurrence between day 7 and day 180 by Cox's proportional hazards regression (efficacy analysis). (cdc.gov)
  • Renal cell carcinoma is an immunogenic tumor, and spontaneous regressions have been documented. (medscape.com)
  • En este estudio, examinamos si la intoxicación por TAA puede inducir la infiltración de leucocitos renales (medida como antígeno leucocitario común CD45) asociada con el aumento de las especies reactivas de oxígeno (ROS)/factor de necrosis tumoral-alfa (TNF-α), así como biomarcadores de daño renal con y sin tratamiento con metformina. (bvsalud.org)
  • Usando tinción histológica básica, métodos de inmunohistoquímica y análisis químico de la sangre, observamos una lesión profunda del tejido renal, como daño glomerular y tubular en el grupo experimental, que mejoraron sustancialmente con la metformina. (bvsalud.org)
  • La metformina también inhibió significativamente (p0,05) en la expresión renal de células de inmunotinción positivas para CD45. (bvsalud.org)
  • En conclusión, encontramos que el TAA induce la lesión renal en asociación con el aumento del eje ROS/TNF-α, independientemente de la infiltración de leucocitos, que está protegida por metformina. (bvsalud.org)
  • The EHE showed nuclear atypia, necrosis and high mitotic figures. (springeropen.com)
  • Patients who present with effusion or seroma (70%) and/or distinct mass formations (30%), as well as patients with breast masses, showed worse overall survival and progression-free survival [ 7 ]. (e-aaps.org)
  • Ultrasonography showed masses in both lobes of the thyroid gland, and a 30-mm lobulated hypoechoic mass in the axilla with well-defined and rough borders, showing internal heterogeneity. (springeropen.com)
  • As shown in Table 2 [21], patients with SS-LCH account for the majority of LCH patients. (mayabouchenaki.com)
  • The transcriptome study was expected to confirm activation of these pathways and show whether others were affected by the treatment. (eurekalert.org)
  • We report a case of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), which had a history of spontaneous resorption of late seroma before diagnosis. (e-aaps.org)
  • Animal studies have shown that energy restriction results in a reduced risk of cancer. (bmj.com)
  • 3 Energy restriction limited to very early life has been shown to result in reduced risk of cancer, 4 and delays in both onset and progression of cancer have been found. (bmj.com)
  • Whereas the thyroid gland showed faint FDG accumulation and multiple lung nodules showed no accumulation, FDG accumulation with a standardized uptake value maximum of 5.1 was observed in the right axillary tumor (Fig. 1 a-d). (springeropen.com)
  • However, a subset (approximately one-third) of combined BN seemed to show true LEF1 expression. (bvsalud.org)
  • During the immunologically mediated regression phase, the central keratin plug is extruded, and only a flat scar remains. (medscape.com)
  • Follow up ultrasound at 3 months, and 1 year showed a viable ovary on both the sides. (heraldopenaccess.us)
  • Plain radiographs show hepatomegaly and characteristic scattered areas of radiolucency outlined by calcific rings 2 to 4 mm in diameter. (cdc.gov)
  • Although functions for discharge pattern didn't show region specificity, the probability mass function of inter-spike period have been diverse for all you 3 areas. (bcl2signaling.com)
  • Periodic evaluation of the affected site is recommended until spontaneous resolution occurs. (medscape.com)
  • These results show that LMP1 , mour viruses classified by IARC in EBV-specific T-cell response. (who.int)
  • Cytology of the aspirated fluid showed atypical cells. (e-aaps.org)
  • We tested a range of concentrations of the Rho inhibitor C3 transferase (C3) and ROCK Nocodazole purchase inhibitor Y27632 that have been shown to promote SCI repair in vivo. (anti-cancers.com)
  • 1 It was shown some 60 years ago that energy restriction in an otherwise adequate diet extended life expectancy in rats considerably, 2 and the animal evidence for a positive relation between dietary intake during the growth period and later incidence of cancer is now well established. (bmj.com)
  • a) Peripheral nerve in longitudinal section stained with Luxol fast blue-periodic acid-Schiff (PAS) showing scattered wallerian degeneration (arrowheads). (medscape.com)
  • There is an uncertain differentiation (there is no evidence yet showing that EMC exhibits the feature of cartilaginous differentiation) and neuroendocrine differentiation is even possible. (wikipedia.org)