• opioid
  • It is a moderately potent opioid pain medication (orally roughly 1.5 times more potent than morphine), generally indicated for relief of moderate to severe pain. (wikipedia.org)
  • There are various sources of input to the vomiting center: The chemoreceptor trigger zone at the base of the fourth ventricle has numerous dopamine D2 receptors, serotonin 5-HT3 receptors, opioid receptors, acetylcholine receptors, and receptors for substance P. Stimulation of different receptors are involved in different pathways leading to emesis, in the final common pathway substance P appears involved. (wikipedia.org)
  • frequent severe
  • Alosetron was withdrawn from the U.S. market in 2000 due to unacceptably frequent severe side effects, including ischemic colitis, and is only available through a restrictive program to patients who meet certain requirements. (wikipedia.org)
  • Pain
  • This condition severely affects patient satisfaction, with postoperative vomiting (POV) ranking above postoperative pain in least-desirable outcome. (frontiersin.org)
  • A 2006 review found that controlled-release oxycodone is comparable to instant-release oxycodone, morphine, and hydromorphone in management of moderate to severe cancer pain, with fewer side effects than morphine. (wikipedia.org)
  • When first introduced in Germany during World War I, both IV and IM administrations of oxycodone were commonly used for postoperative pain management of Central Powers soldiers. (wikipedia.org)
  • Butorphanol is frequently used for post-operative and accident-related pain in small mammals such as dogs, cats, ferrets, coatis, raccoons, mongooses, various marsupials, some rodents and perhaps some larger birds, both in the operating suite and as a regular prescription medication for home use, for management of moderate to severe pain. (wikipedia.org)
  • Back pain and headache - often severe and possibly associated with nausea, vomiting, neck rigidity and pain or discomfort in the eyes due to light exposure (photophobia) - are frequently the first symptoms of meningeal carcinomatosis. (wikipedia.org)
  • Brachial plexopathy Brachial plexopathy is a common product of Pancoast tumor, lymphoma and breast cancer, and can produce severe burning dysesthesic pain on the back of the hand, and cramping, crushing forearm pain. (wikipedia.org)
  • It is commonly felt as tenderness, with constant background pain and instances of spontaneous or movement-related exacerbation, and is frequently described as severe. (wikipedia.org)
  • Fracture Rib fractures, common in breast, prostate and other cancers with rib metastases, can cause brief severe pain on twisting the trunk, coughing, laughing, breathing deeply or moving between sitting and lying. (wikipedia.org)
  • medication
  • The percentages of patients with total control (no vomiting, no moderate-to-severe nausea, and no use of rescue medication over 0 to 6 hours) were 65%, 56%, 67%, and 33%, respectively. (cancernetwork.com)
  • It has also been used as an antipsychotic in doses ranging from 5 to 10 mg given as an intramuscular injection, generally in cases of severe agitation in a psychotic patient who is refusing oral medication. (wikipedia.org)
  • stomach
  • Nausea is an abdominal discomfort or queasiness that may be accompanied by vomiting (the forceful expulsion of stomach contents through the mouth ). (nih.gov)
  • Nausea is a sensation of unease and discomfort in the upper stomach with an involuntary urge to vomit. (wikipedia.org)
  • Vomiting, also known as emesis and throwing up, among other terms, is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. (wikipedia.org)
  • Severity
  • Postoperative vomiting and/or retching is easier to quantify as an end point in an antiemetic drug study because no subjective evaluation of the severity of emetic symptoms is required, and the collection of data is straightforward and unambiguous. (lww.com)
  • This review sought to establish what effect the use of aromatherapy has on the severity and duration of established postoperative nausea and vomiting and whether aromatherapy can be used with safety and clinical effectiveness comparable to standard pharmacological treatments . (nih.gov)
  • surgery
  • Quality of recovery on the morning after surgery -using the validated QoR Score instrument (14), a 9-item patient-orientated measure of early postoperative health status. (clinicaltrials.gov)
  • One exception is a condition called long-term postoperative cognitive dysfunction, characterized by persistent confusion lasting weeks or months, which is more common in those undergoing cardiac surgery and in the elderly. (wikipedia.org)
  • Has produced postoperative infections after breast augmentation surgery. (wikipedia.org)
  • citation needed
  • citation needed] Lorazepam (Ativan) is said to be very good as an adjunct treatment for nausea along with first line medications such as Compazine. (wikipedia.org)
  • citation needed] Cancer and nausea Emetic - substances that induce nausea and vomiting Quinlan, Jeffrey D. (wikipedia.org)
  • citation needed] Repeated or profuse vomiting may cause erosions to the esophagus or small tears in the esophageal mucosa (Mallory-Weiss tear). (wikipedia.org)
  • citation needed] Receptors on the floor of the fourth ventricle of the brain represent a chemoreceptor trigger zone, known as the area postrema, stimulation of which can lead to vomiting. (wikipedia.org)
  • Intrathecal
  • 12 In addition, although nausea has not been reported in these studies, other side effects, which were present in initial studies of intrathecal neostigmine, including sedation, 5 and those from peripheral muscarinic receptor stimulation, including salivation and sweating, were not systematically assessed. (asahq.org)
  • chemotherapy
  • Clinical trials suggest that it is more effective than other 5-HT3 antagonists in preventing delayed CINV (nausea and vomiting that occur more than 24 hours after the first dose of chemotherapy). (wikipedia.org)
  • Nausea is a side effect of many medications including chemotherapy, or morning sickness in early pregnancy. (wikipedia.org)
  • Symptoms
  • The risk of experiencing severe withdrawal symptoms is high if a patient has become physically dependent and discontinues oxycodone abruptly. (wikipedia.org)
  • treatment
  • While usually it is mild and self-limiting, severe cases known as hyperemesis gravidarum may require treatment. (wikipedia.org)
  • Topical formulations of haloperidol should not be used as treatment for nausea because research does not indicate this therapy is more effective than alternatives. (wikipedia.org)
  • Severe infections require IV treatment combined with oral antibiotics for a prolonged period, up to several months. (wikipedia.org)