• Gamma-glutamyl transferase (GGT) is a cellular production of oxidants. (medscimonit.com)
  • Subjects with suspected liver disease (SLD), defined on the basis of elevated serum alanine aminotransferase (ALT) and gamma-glutamyl-transferase (GGT) activity, hepatitis B surface antigen (HBsAg), or hepatitis C virus (HCV)-RNA positivity, were matched with randomly selected subjects of the same age and sex without SLD. (nih.gov)
  • Gamma glutamyl transferase (GGT) enzyme maintains the GSH-cysteine homeostasis as well as detoxifies the toxic molecules thereby lower oxidative stress in the body. (journalcra.com)
  • Objective: To compare clinicopathologic features of idiopathic IgA nephropathy in terms of serum gamma-glutamyl transferase (GGT) levels. (afsu.edu.tr)
  • On March 6, a routine blood chemistry screen showed elevations of total bilirubin, alkaline phosphatase, gamma glutamyl-transferase, serum glutamic oxalacetic transaminase, and lactate dehydrogenase. (cdc.gov)
  • Lower serum albumin, higher serum gamma-glutamyl transferase (GGT), lower estimated glomerular filtration rate (eGFR), older age, higher temperature, and lower absolute lymphocyte count at admission were independent predictors of all-cause mortality after 12 months. (wustl.edu)
  • Whilst alanine transaminase (ALT), creatine kinase (CK), creatinine, and gamma-glutamyl transferase (GGT) concentrations changed substantially at room temperature, there was less than 4% change during chilled storage up to 7 days. (ox.ac.uk)
  • This study was undertaken to determine the influences of various doses of peppermint oil on the hepatic en-zymes, alanine transaminase, apartate tranaminase, alkaline phosphotase and gamma glutamyl transferase and the level of malondialdehyde in the serum of mice with and without immobility stress. (openbiochemistryjournal.com)
  • In an experiment conducted in 2015, the levels of serum alanine aminotransferase, aspartate aminotransferase, gamma glutamyl transferase, alkaline phosphatase and total bilirubin were significantly increased after treating Wistar male rats with thioacetamide, and consuming rosemary leaf extract had a protective effect in rats with thioacetamide-induced liver cirrhosis. (herbalteashop.ir)
  • Gamma glutamyl transferase (GGT) is an enzyme found in cell membranes of many tissues mainly in the liver, kidney, and pancreas. (medscape.com)
  • However, the study did show promising data in post-hoc analysis, achieving significance in the secondary endpoint of reduction in alkaline phosphatase (ALP). (wikipedia.org)
  • The major clinical value of serum GGT is in evaluating patients with isolated elevation in alkaline phosphatase because differentiating between hepatobiliary and bone causes in these cases can be difficult. (medscape.com)
  • The purpose of the present study was to elucidate the role of serum GGT, magnesium and albumin in relation to hyperglycemia in type 2 diabetic patients. (journalcra.com)
  • Serum GGT, magnesium, albumin and fasting blood glucose were estimated and data was statistically analyzed. (journalcra.com)
  • Conclusions: Increased serum GGT activity and low Mg and albumin levels are markers of high oxidative stress and metabolic disturbances in type 2diabetes. (journalcra.com)
  • After 5 weeks, mice were fasted and blood was withdrawn for biochemical analysis including alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyltransferase (GGT), serum creatinine and urea. (scialert.net)
  • Addition of either raw or g-irradiated basil (1%) to the diet of MTX-rats has significantly reduced the activities of serum enzymes and the levels of serum urea, creatinine and uric acid accompanied by ameliorating the alteration in the antioxidant/oxidant status of the liver and kidney. (arccjournals.com)
  • Hepatorenal syndrome is diagnosed when a creatinine clearance rate of less than 40 mL/min is present or when a serum creatinine level of greater than 1.5 mg/dL, a urine volume of less than 500 mL/day, and a urine sodium level of less than 10 mEq/L are present. (medscape.com)
  • The aim of this retrospective multicenter study was to assess potential risk factors for procedure-related bleeding (PRB) within 30 days after first elective/prophylactic EBL in patients with liver cirrhosis and portal hypertension. (springer.com)
  • This retrospective study was conducted in two tertiary clinical centers (Vienna General Hospital of the Medical University of Vienna and Klinik Landstrasse in Vienna) including patients with liver cirrhosis and portal hypertension. (springer.com)
  • Patients with non-cirrhotic portal hypertension receiving EBL, other than EBL endoscopic treatment, previous transjugular intrahepatic portosystemic shunt (TIPS) implantation or orthotopic liver transplantation, occlusive portal vein thrombosis, patients with fundal varices only, patients with acute and/or uncontrolled variceal bleeding at baseline and insufficient medical/endoscopic records were excluded from this study. (springer.com)
  • Serum liver enzymes levels within the normal range were categorized into quartiles, and their relationship with diabetes was evaluated by logistic regressions. (biomedcentral.com)
  • In this respect, although many studies have shown a relation between diabetes and elevated liver enzymes, the results remain inconsistent [ 12 ]. (biomedcentral.com)
  • Coordinating Center for alpha-1 antitrypsin deficiency-related liver disease of the European Reference Network (ERN) 'Rare Liver' and the European Association for the Study of the Liver (EASL) registry group 'Alpha-1 Liver,' University Hospital Aachen, Aachen, Germany. (nih.gov)
  • Up to 90 days daily oral crude neem oil treatment (5 g/kg body weight) of laboratory mice did not cause any significant changes in weekly body weight gain, nor in serum liver damage indicators, direct bilirubin or total bilirubin. (who.int)
  • Histological and histochemical studies on the effects of mehotrexate on the liver of adult male albino rat. (arccjournals.com)
  • The aim of the study was to evaluate the subacute toxicity of melanin in terms of biochemical and pathomorphological changes in the liver of rats. (kiev.ua)
  • The enzyme catalyzes the transfer of the gamma-glutamyl group from gamma-glutamyl peptides, such as glutathione to an acceptor such as peptides and L-amino acids. (medscape.com)
  • Blood serum samples were analyzed for PCB congeners using gas chromatography/mass spectroscopy (GC/MS). Results were reported as concentrations of individual PCB congeners per unit volume of blood serum, and also as lipid-based concentrations. (cdc.gov)
  • This study investigated the association between prediagnostic circulating vitamin D concentrations and dietary intakes of vitamin D, and the risk of Crohn's disease (CD) and ulcerative colitis (UC). (bvsalud.org)
  • The therapeutic effect of FIRMAGON should be monitored by measuring serum concentrations of prostate-specific antigen (PSA) periodically. (firmagon.com)
  • If PSA increases, serum concentrations of testosterone should be measured. (firmagon.com)
  • Peak serum concentrations in healthy adults and pediatric populations vary widely from individual to individual. (nih.gov)
  • Peak serum concentrations of 10.7±3.7 and 11.5±5.1 mcg/mL were obtained 1 hour after preprandial ingestion of the drug suspension and the applesauce mixture, respectively. (nih.gov)
  • We aimed to elucidate the relationship of serum GGT levels and coronary artery disease (CAD) in a Chinese population. (medscimonit.com)
  • Here, the aim of this work was to investigate the effect of g-radiation processing on the total phenolic and total flavonoids content of dried basil as well as to study the protective role of g-irradiated dried basil leaves against MTX-induced hepatic and renal toxicity in rats. (arccjournals.com)
  • An elevated arterial or free venous serum ammonia level is the classic laboratory abnormality reported in patients with hepatic encephalopathy. (medscape.com)
  • Computed tomography (CT) scanning and MRI studies of the brain may be important in ruling out intracranial lesions when the diagnosis of hepatic encephalopathy is in question. (medscape.com)
  • Clinical characteristics, coronary angiography, and serum samples were collected from all the patients and analyzed for the serum GGT, blood lipids, and cardiovascular risk factors. (medscimonit.com)
  • As only few original studies have investigated acute pancreatitis in children in Iran, in the present study, the clinical manifestations and etiological factors of this disease, as well as diagnostic and therapeutic measures, were investigated in children. (biomedcentral.com)
  • Other activities carried out by the IPCS include the development of know-how for coping with chemical accidents, coordination of laboratory testing and epidemiological studies, and promotion of research on the mechanisms of the biological action of chemicals. (inchem.org)
  • Elevated serum levels of ALT, AST, GGT and ALP were defined according to the reference range of the laboratory in the cohort center. (biomedcentral.com)
  • Purpose In our study, diagnostic and demographic characteristics of patients diagnosed with minimal change disease (MCD) by biopsy, clinical and laboratory findings in our country were investigated. (afsu.edu.tr)
  • The study was carried out on 80 Wistar white laboratory rats weighing 180-260 g. (kiev.ua)
  • We used data obtained from the Rafsanjan Cohort Study (RCS), as a part of the prospective epidemiological research studies in IrAN (PERSIAN). (biomedcentral.com)
  • Stability of plasma analytes after delayed separation of whole blood: implications for epidemiological studies. (ox.ac.uk)
  • BACKGROUND: Large blood-based epidemiological studies require simple, cost-effective sample collection methods. (ox.ac.uk)
  • Mailed transport of whole blood samples may, therefore, be a simple and cost-effective option for large-scale epidemiological studies. (ox.ac.uk)
  • As Hulka has so clearly stated, "the most important current limitation in many epidemiological studies is the relative inac- curacy of methods for measuring the exposure variable" (2). (cdc.gov)
  • Bone formation markers in serum and urinary resorption markers were measured at baseline, and after 6 and 12 months. (biomedcentral.com)
  • This is a randomized, parallel-group, double-blind, placebo-controlled, multi-center, phase II study in which patients, treating physicians, and the associated clinical staff as well as the sponsor clinical team are blinded. (biomedcentral.com)
  • The study patient has been informed of the nature of the study, agrees to its provisions and has provided written informed consent as approved by the institutional review board (IRB) of the respective clinical site. (healthstudiesmn.org)
  • In a study, published in International Journal of Clinical Medicine, consuming rosemary could decrease lipid peroxidation and improve lipid profile in human. (herbalteashop.ir)
  • Serum GGT levels may be a potential biomarker for CAD. (medscimonit.com)
  • Some significant changes in the blood biochemistry parameters were found in the treatment groups including levels in bile acid, haptoglobin, total serum protein, and GTT, as well as creatine kinase activity, but those changes were not toxicologically significant because no observed changes were seen in other similar biomarkers. (scirp.org)
  • Serum 25-hydroxyvitamin D levels were measured using liquid chromatography-tandem mass spectrometry. (bvsalud.org)
  • Generally men have higher levels of serum iron than women. (irondisorders.org)
  • The most common adverse reactions (≥10%) during FIRMAGON therapy included injection site reactions (eg, pain, erythema, swelling, or induration), hot flashes, increased weight, fatigue, and increases in serum levels of transaminases and gamma-glutamyltransferase. (firmagon.com)
  • ABSTRACT This study was conducted to investigate the preliminary environmental and mammalian toxicol- ogy of neem oil, temephos and chlorpyriphos-methyl/fenitrothion. (who.int)
  • Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o. (medscimonit.com)
  • The purpose of this study was to evaluate the relationship between leukocyte count, a marker of systemic inflammation, and incidence of SAH in a large cohort study. (biomedcentral.com)
  • Considering the limitation of studies investigating the relationship between T. gondii and cardiovascular biomarkers, this study was focused on assessing the association of T. gondii to nine cardiovascular biomarkers. (mdpi.com)
  • In this regard, some studies have found that lithium and hyperbaric oxygen[4] reduce oxidative stress and may increase blood flow to the brain, lending some support to the idea that a possible endophenotype leads to oxidative stress and neuronal injury. (medscape.com)
  • This study investigated the effect of the trans-resveratrol supplementation on the cardiac oxidative stress in rats exposed to cigarette smoke. (bvsalud.org)
  • Recent studies have raised questions concerning the cytotoxic effects on the kidney from exposure to uranium in experimental animal settings vs. in humans. (cdc.gov)
  • This study confirms previous studies demonstrating the predominance of Aspergillus species in herbal and medicinal plants and its capability in the production of aflatoxin with induction of nephrotoxicity and hepatoxicity in animals and even in humans. (scialert.net)
  • The main objective of this study was to investigate the prevalence of T. gondii among adults in the United States and its association with cardiovascular health using data from the National Health and Nutrition Examination Survey (NHANES 2009-2010). (mdpi.com)
  • Trends in HPV cervical and seroprevalence and associations between oral and genital infection and serum antibodies in NHANES 2003-2012. (cdc.gov)
  • Based on the evaluation of medical records, patients under the age of 18 years, who met the diagnostic criteria for acute pancreatitis according to the INSPPIRE criteria, were included in the study. (biomedcentral.com)
  • In an extension study, 135 patients crossed over from leuprolide to FIRMAGON. (firmagon.com)
  • The efficacy and safety of degarelix: a 12-month, comparative, randomized, open-label, parallel-group phase III study in patients with prostate cancer. (firmagon.com)
  • In a study it was observed that using the extract of Perilla frutescens enriched with rosmarinic acid had a positive effect on patients with seasonal allergic rhinoconjunctivitis allergy along with fatigue, cough and eye symptoms. (herbalteashop.ir)
  • In one study, pediatric patients 6 to 58 months old were given rifampin suspended in simple syrup or as dry powder mixed with applesauce at a dose of 10 mg/kg body weight. (nih.gov)
  • Le succès de cette étape nécessite également le rapprochement entre pédiatres et médecins d'adultes pour une prise en charge optimal des patients. (bvsalud.org)
  • RÉSUMÉ Tous les patients de sexe masculin soignés en psychiatrie et en médecine générale adressés à deux hôpitaux de Basra (Iraq) de septembre 2000 à avril 200l ont été soumis à un dépistage de l'alcoolisme par le test AUDIT (Alcohol Use Disorder Identification Test). (who.int)
  • Incidence of SAH in relation to baseline leukocyte concentration was studied during a mean follow-up of 27 years in participants free from previous stroke. (biomedcentral.com)
  • Leukocyte concentration in relation to incidence of SAH has, to our best knowledge, not earlier been studied. (biomedcentral.com)
  • Furthermore, in 1992 Mourkarzel [ 21 ] reported that a decreased serum Si concentration in total parenterally fed infants was associated with a decreased bone mineral content compared to healthy controls. (biomedcentral.com)
  • Following a single 600 mg oral dose of rifampin in healthy adults, the peak serum concentration averages 7 mcg/mL but may vary from 4 to 32 mcg/mL. (nih.gov)
  • Iron contained in blood serum (or plasma) is normally bound to the protein transferrin. (irondisorders.org)
  • A statistically significant delay inthe appearance of sulfapyridine in serum was obtained after active treatment versus control treatment, corresponding to a45-min longer orocecal transit time due to fat emulsion consumption. (marysfamilymedicine.org)
  • Subjects with CAD had significantly increased activity of serum GGT (p=0.003). (medscimonit.com)
  • In another open intervention study [ 23 ] femoral density was significantly increased after intramuscular administration of silicon (50 mg), again, as monometyltrisilanol twice a week for 4 months. (biomedcentral.com)
  • The study doses were determined based on the maximum tolerated dose of 200 mg/kg body weight with single administration. (kiev.ua)
  • In healthy adults, the mean biological half-life of rifampin in serum averages 3.35±0.66 hours after a 600 mg oral dose, with increases up to 5.08±2.45 hours reported after a 900 mg dose. (nih.gov)
  • Previous large observational cohort studies showed higher blood pressure (BP) positively associated with cancer. (biomedcentral.com)
  • The 111-patient study tested two doses of setanaxib, 400 mg once daily and 400 mg twice daily, versus placebo. (wikipedia.org)
  • 1.5) completed the study and received, daily, 1000 mg Ca and 20 μg cholecalciferol (Vit D3) and three different ch-OSA doses (3, 6 and 12 mg Si) or placebo. (biomedcentral.com)
  • 13. For participants taking allowed antipsychotic, antidepressant, or other psychotropic medication, the dosing of medication as listed in Section 10.6, must be stable for at least 4 weeks before the Baseline visit and throughout the study (unless clinically necessary to change). (who.int)
  • From baseline to end of study, the median change for FIRMAGON was 12.3 msec and 16.7 msec for leuprolide. (firmagon.com)
  • Descriptive statistics were used to characterize the blood serum and environmental media PCB data. (cdc.gov)
  • Sub-acute toxicity of a natural pigment melanin, produced by Antarctic yeast-like fungi Pseudonadsoniella brunnea was studied in rats. (kiev.ua)
  • One of the first stages of such development is the study of melanin toxicity. (kiev.ua)
  • The study of subacute toxicity lasted 14 days. (kiev.ua)
  • Several years ago, the Environmental Protection Agency co- sponsored a National Research Council study on The Role of Biomarkers in Reproductive and Developmental Toxicology (5). (cdc.gov)
  • It is not known whether systemic low-grade inflammation is associated with the incidence of SAH, and only two prospective studies have addressed this question. (biomedcentral.com)
  • In this study we investigated the association between leukocyte count and incident SAH in a large prospective cohort study from an urban population. (biomedcentral.com)
  • However, with an adeq battery of necf expsre blmarkers, prospective studies of en- vironmental effects on pregnancy outcomes might be possible. (cdc.gov)
  • Key Words: Appetite, ileal break, orocecal transit time, overweight, weight maintenance ''Fabuless'' is a stable fat emulsion consisting of palm oil and oat oil that can reduce food intake and Overweight and obesity have become a global epi- enhance satiety [4 7], although not all such studies demic, associated with significant increases in mor- have yielded significant effects [8]. (marysfamilymedicine.org)
  • From the study, the best peptides for burning fat include a. (chainway.net.ua)
  • This measurement indicates the potential capacity of transferrin molecules to bind with serum iron. (irondisorders.org)
  • The aim of this study was to investigate the common causes and routine diagnostic and therapeutic methods of acute pancreatitis in children in a pediatric gastrointestinal referral center and its accordance with existing guidelines. (biomedcentral.com)
  • 11. Female participants of childbearing potential whose male partners are potentially fertile (i.e., no vasectomy) must use highly effective birth control methods stable for at least 3 months prior to screening, for the duration of the study and for 30 days after discontinuation of the study drug. (who.int)
  • 12. Male participants must be sterile, or if they are potentially fertile/reproductively competent (not surgically [e.g., vasectomy] or congenitally sterile) and their female partners are of childbearing potential, they must use, together with their female partners, effective birth control methods for the duration of the study and for 90 days after study drug discontinuation. (who.int)
  • Object and methods of study. (kiev.ua)
  • Methods A cross-sectional study among 374 students recruited using stratified sampling was conducted. (bvsalud.org)
  • Briefly, RCS is a cohort population based study that initiated in August 2015 in Rafsanjan, an area in the southeast of Kerman province of Iran. (biomedcentral.com)
  • Introduction: This study aimed to investigate the role of mean platelet volume (MPV) in predicting renal outcome in acute kidney injury (AKI) developing on pre-existing chronic kidney disease (CKD). (afsu.edu.tr)
  • A total of 513 adult subjects who had undergone coronary angiography were enrolled in the study. (medscimonit.com)
  • In this study, twenty five samples of well-known herbs in Riyadh, Saudi Arabia were collected and analyzed for Total Fungi Count (TFC). (scialert.net)
  • In this retrospective, cross-sectional study, a total of 60 children with a diagnosis of acute pancreatitis, were studied. (biomedcentral.com)
  • In this retrospective, cross-sectional study, a total of 60 children with a diagnosis of acute pancreatitis, admitted to Children's Medical Center Hospital in Tehran, Iran, from 2013 to 2020, were studied. (biomedcentral.com)
  • Total iron binding capacity (TIBC) is often measured at the same time as serum iron. (irondisorders.org)
  • Infiltration of inflammatory cells and increased expression of inflammatory mediators have been observed in the aneurysm wall in histological studies, and are more pronounced in ruptured than unruptured aneurysms. (biomedcentral.com)
  • When laboratories measure serum iron they often also measure transferrin and calculate the percentage of transferrin molecules that are used to bind iron. (irondisorders.org)
  • Transferrin saturation percentage (TS %) is calculated by dividing serum iron by TIBC, then multiplying by 100. (irondisorders.org)
  • Subjects must have an Argus II device implanted to be eligible for this study. (healthstudiesmn.org)
  • the study did not meet this endpoint. (wikipedia.org)
  • The study consists of a maximum 6-week screening period, a 52-week treatment period (including the 26-week tapering), and an 8-week safety follow-up, with primary and secondary endpoint assessments at week 28. (biomedcentral.com)
  • Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study. (liver.at)
  • Candidate thesis on "Study of the effect of chronic alcohol intoxication on the metabolism of zinc, copper and lithium in the body" was defended, speciality 14.00.45 - Narcology. (rudn.ru)
  • The ethi- tice has shown that alcohol dependence or cal committee of the College of Medicine harmful alcohol use is present in about 6% approved the study protocol. (who.int)
  • More research should be done to study the association between COVID-19 and acute pancreatitis. (biomedcentral.com)
  • The results of surveys, analyses, and studies are made known through a number of data release mechanisms including publications, mainframe computer data files, CD-ROMs (Search and Retrieval Software, Statistical Export and Tabulation System (SETS)), and the Internet (http://www.cdc.gov/nchswww/nchshome.htm). (cdc.gov)
  • Method and Results: The study comprised of 50 diagnosed cases of type 2 diabetes mellitus and 30 age and sex matched healthy controls. (journalcra.com)
  • Further studies are needed to confirm our results and identify therapeutic strategies to improve survival. (wustl.edu)
  • This result may suggest that, MDA level is higher in immobilization stress group than in the un-immobilized animals in serum and this results show that enzyme activities decreased after immobilization stress. (openbiochemistryjournal.com)
  • The results of this study were published in the Journal of Medicinal Food. (herbalteashop.ir)
  • According to the results of this study, the hepatoprotective effects of rosemary extract may be due to its antioxidant features. (herbalteashop.ir)
  • The results of this study revealed the healing effect of the extract, having antioxidant and anti-inflammatory properties, on gastric ulcer. (herbalteashop.ir)
  • 2002]. In another study, uranium was measured in 193 people who used drinking water from drilled wells for an average of 16 years. (cdc.gov)
  • In sum, this study demonstrated that the addition of Sangrovit ® to swine feed at up to 1000 mg/kg does not result in any toxicological effects to the health status and growth of weaned piglets. (scirp.org)
  • The rat is commonly used species for toxicological studies in accordance with international recommendations. (europa.eu)
  • Outcomes that may occur with uranium exposure based on both observed human effects and animal studies include non-malignant respiratory disease (fibrosis, emphysema) and nephrotoxicity. (cdc.gov)
  • Two-part random effects models have been applied to longitudinal studies for semi-continuous outcomes, characterized by a large portion of zero values and continuous non-zero (positive) values. (blogspot.com)