• 1982
  • Allele Query Form IMGT/HLA - European Bioinformatics Institute Gregoriadis S, Zervas J, Varletzidis E, Toubis M, Pantazopoulos P, Fessas P (December 1982). (wikipedia.org)
  • genes
  • Progress on non-HLA genes affecting adverse drug reactions has been less, but some important associations, such as those of SLCO1B1 and statin myopathy, KCNE1 and drug-induced QT prolongation and NAT2 and isoniazid-induced liver injury, are considered. (biomedcentral.com)
  • class
  • Examination of the virus itself has led to the discovery of strains that can all but turn off the A11-mediated class I response to the virus in A11 enriched peoples (see tables below). (wikipedia.org)
  • The number of mismatched HLA-A/B/C eplets strongly correlated with the rate of child-specific class I sensitization. (wiley.com)
  • delivery
  • Other studies indicated that peptides bind A11 in delivery to the cell surface for CTL screening, but fall off, and are destroyed intracellularly. (wikipedia.org)
  • The aim of this study was to define the frequency and determinants of pregnancy-induced child-specific sensitization shortly after full-term delivery using sensitive single HLA-antigen beads (SAB) and high resolution HLA-typing of the mothers and their children (n = 301). (wiley.com)
  • Therefore, knowledge on the frequency and determinants of child-specific HLA-antibody production soon after delivery could be very helpful to better assess the likelihood of pregnancy-induced sensitization even in the absence of HLA-antibodies in current sera. (wiley.com)
  • Analysis
  • Therefore, pretransplant evaluation of renal allograft recipients includes a sensitization history and a thorough analysis of HLA-antibodies in current and remote sera [ 1 ]. (wiley.com)