• protease
  • We demonstrate here that mutations affecting the RhoA signaling pathway also interact genetically with mutations in the Stubble-stubbloid ( Sb-sbd ) locus that encodes an unusual type II transmembrane serine protease required for normal leg and wing morphogenesis. (genetics.org)
  • FSAP (Factor VII-activating protease) is a novel plasma-derived serine protease that regulates haemostasis as well as vascular cell proliferation. (biochemj.org)
  • proteins
  • Our results provide evidence that the type II transmembrane serine proteases, a class of proteins linked to human developmental abnormalities and pathology, may be associated with intracellular signaling required for normal development. (genetics.org)
  • type
  • The serine type of endopeptidase shows activity in the cytosol, but is still not able to digest polypeptides containing more than 30 amino acid residues. (mdpi.com)