• Yesterday, 10x said that it is partnering with Qiagen to co-develop and co-market next-generation sequencing and single-cell biology analysis workflows and informatics solutions. (genomeweb.com)
  • Traditional Sanger sequencing and next-generation sequencing are used to sequence viruses in basic and clinical research, as well as for the diagnosis of emerging viral infections, molecular epidemiology of viral pathogens, and drug-resistance testing. (wikipedia.org)
  • Seven Bridges' CGC platform is one of three cloud pilots initiated by the National Cancer Institute (NCI), with the goal of making next-generation sequencing (NGS) data like The Cancer Genome Atlas (TCGA) dataset more accessible and useful to researchers worldwide. (sevenbridges.com)
  • Ion S5™ System - In combination with the Ion Chef™ system for automated library and template preparation, the Ion S5 next-generation sequencing systems enable the simplest targeted sequencing workflow for your lab. (thermofisher.com)
  • Next-generation sequencing (NGS) has revolutionized molecular biology and served as a universal tool for many research avenues across the spectrum of biology. (bio-itworld.com)
  • With the advancement of next-generation sequencing and mass spectrometry, there is a growing need for the ability to merge biological features in order to study a system as a whole. (rsc.org)
  • The study, Orthogonal Next Generation Sequencing (NGS) for High Throughput Clinical Diagnostics was published today in the online edition of Scientific Reports. (claritasgenomics.com)
  • There is no doubt that we have big data in the field of genomics in general and Next Generation Sequencing specifically. (goldenhelix.com)
  • To do this, WHO Member States in the Eastern Mediterranean Region (EMR) needed to develop a new framework for laboratory strengthening, considering lessons learned since 2016 when the regional strategic framework for strengthening health laboratory services 2016-2020 (3) (extended until 2023) was developed and endorsed. (who.int)
  • The technical working group constituted by the directors of public health laboratories in the EMR held their first meeting in March 2023 to review implementation of the 2016-2020 framework, finalize the strategic priorities for the next regional framework, and develop a strategy to implement SLMTA in the EMR. (who.int)
  • The authors acknowledge support from the National Genomics Infrastructure in Stockholm funded by Science for Life Laboratory, the Knut and Alice Wallenberg Foundation and the Swedish Research Council, and SNIC/Uppsala Multidisciplinary Center for Advanced Computational Science for assistance with massively parallel sequencing and access to the UPPMAX computational infrastructure. (lu.se)
  • Relatively fast, inexpensive and accurate, short read sequencing (technically known as high throughput massively parallel sequencing) requires breaking the genome into millions of short-250 bases, plus or minus-segments for sequencing and then reassembling them to generate the full sequence. (jax.org)
  • The Database of Chromosome Aberrations and Gene Fusions in Cancer, established in 1980, is an attempt to register systematically all published cytogenetic aberrations reported in cancer, including patient and tumor characteristics, gene fusions identified by cytogenetics or massively parallel sequencing, and studies pertaining to the clinical relevance of cytogenetic aberrations and/or gene rearrangements. (lu.se)
  • On October 11, 2017, the Precision Medicine and Population Health Interest Group in the Division of Cancer Control and Population Sciences at the National Cancer Institute, the National Institutes for Health Genomics and Health Disparities Interest Group , and the CDC Office of Public Health Genomics co-sponsored a special one-hour online webinar that explored the intersection of genomics, precision medicine, and health disparities. (cdc.gov)
  • NEW YORK (GenomeWeb) - 10x Genomics has announced two new sequencing partnerships with Qiagen and Illumina. (genomeweb.com)
  • Separately, 10x and Illumina said today that they are partnering to co-market Illumina's sequencing systems and 10x's linked-read sequencing products. (genomeweb.com)
  • 10x's microfluidics-based molecular barcoding long read solutions, built on the GemCode platform, can be used with Illumina sequencers to give researchers a wider range of sequencing applications to choose from, the company said. (genomeweb.com)
  • We are excited to establish this ecosystem and to have 10x Genomics as a partner," Illumina Chief Commercial Officer Christian Henry said in a statement. (genomeweb.com)
  • We sequenced the libraries as paired-end reads (150 bp + 150 bp) by using a MiSeq instrument (Illumina). (cdc.gov)
  • To ease future molecular studies, this study compares first- (partial sequencing via Sanger), second- (Illumina), and third-generation (MinION Nanopore) sequencing platforms for USUV. (frontiersin.org)
  • We concluded that depending on the focus of a research project, amplicon-based MinION Nanopore sequencing can be an ideal cost- and time-effective alternative to Illumina in producing optimal genome coverage. (frontiersin.org)
  • The Genomics Unit offers short read (Illumina NexSeq 2000 and Illumina MiSeq) and long read Nanopore sequencing, Library preparation, and Fragment-analyzer/TapeStation sample QC services. (gulbenkian.pt)
  • In this study, the Illumina HiSeq 4000 and PacBio platforms were used to sequence and assemble the whole genome of Fusarium equiseti D25-1. (researchsquare.com)
  • Illumina single nucleotide polymorphism (SNP) chips, kompetitive allele-specific PCR (KASP) assays, genotyping-by-sequencing (GBS)) and sequencing (e.g. (biomedcentral.com)
  • The novel orthogonal sequencing process was run using the Illumina and Ion Torrent NGS technologies. (claritasgenomics.com)
  • For Illumina-based sequencing, DNA was targeted using the Agilent Clinical Research Exome kit. (claritasgenomics.com)
  • Long read sequencing technologies haven't pushed aside short read sequencing or Illumina, the largest company in the field, as some predicted back then, but they are now being applied to a wider range of research applications. (jax.org)
  • After the deoxyribonucleic acid (DNA) sequence of the human genome was completed in 2003, the reference sequence underwent several improvements and today provides the underlying comparative resource for a multitude genetic assays and biochemical measurements. (scienceblogs.com)
  • Genetic analysis is error prone and the data require validation because the methods for collecting DNA sequences create artifacts and the reference sequence used for comparative analyses is incomplete. (scienceblogs.com)
  • DNA sequencing may be used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes, or entire genomes of any organism. (wikipedia.org)
  • Medical technicians may sequence genes (or, theoretically, full genomes) from patients to determine if there is risk of genetic diseases. (wikipedia.org)
  • This is a form of genetic testing, though some genetic tests may not involve DNA sequencing. (wikipedia.org)
  • DNA sequencing allows clinicians to identify genetic diseases, improve disease management, provide reproductive counseling, and more effective therapies. (wikipedia.org)
  • During the pandemic, new possibilities were introduced in the use of genetic sequencing for surveillance. (who.int)
  • OAKLAND, Calif. & DANVERS, Mass. & PHOENIX--( BUSINESS WIRE )-- Fabric Genomics , a global computational genomics company, and Veritas Genetics , the global leader in genetic sequencing and interpretation, announced today at the ACMG Annual Clinical Genetics Meeting that they have entered into a technology partnership. (businesswire.com)
  • Veritas' myGenome is the world's first whole genome test offering, priced less than $1,000, and provides sequencing, interpretation and a call with a genetic counselor, when appropriate. (businesswire.com)
  • By removing barriers to genetic screening and whole genome sequencing, Veritas Genetics empowers individuals and doctors to make informed lifestyle decisions that help people live longer, healthier lives. (businesswire.com)
  • By accelerating access to insights related to the cause of genetic diseases, Fabric Genomics is leading the way in precision healthcare. (businesswire.com)
  • PULLMAN, Wash. - A free, one-day workshop about genetic sequencing technology and research will be presented by the Genomics Core at Washington State University Spokane on the Pullman campus and via video statewide. (wsu.edu)
  • Her work led to the funding of research labs and startups in genetic sequencing and large database work on genotypic/phenotypic associations. (sxsw.com)
  • Orthogonal sequencing is the practice of running two gene sequencing technologies in parallel to assist with the diagnosis of more complex genetic diseases. (claritasgenomics.com)
  • The benefits of broad genetic testing for patients with previously undiagnosed diseases are clear, said John Thompson, Chief Technology Officer for Claritas Genomics, but the speed and diagnostic yield have been problems. (claritasgenomics.com)
  • GCS also uses expertise to identify specific genes and studies, as well as extensive sequencing genomics to explore how the variants may genetic profiles that contribute to the work. (who.int)
  • GCS places more focus on identification scale molecular epidemiology projects of uncommon or rare genetic variants that and other IARC genomics projects. (who.int)
  • By offering empowerment and control, companies convince consumers to sequence their genome by granting the company access to their genetic data in exchange to results that are not always accurate. (bvsalud.org)
  • Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. (genomeweb.com)
  • Advances in genome sequencing, other "omic" technologies, and big data promise a new era of personalized medicine. (cdc.gov)
  • Advances in whole-genome sequencing technologies have enabled numerous key discoveries. (researchsquare.com)
  • Crop genomics has seen dramatic advances in recent years due to improvements in sequencing technology, assembly methods, and computational resources. (biomedcentral.com)
  • Here, we review advances in crop genomics and how utilization of these tools is shifting in light of pan-genomes that are becoming available for many crop species. (biomedcentral.com)
  • Within crop genomics, advances relevant to crop improvement have primarily been in marker (e.g. (biomedcentral.com)
  • It is now timely that the huge advances made in genomics, cell and molecular biology that have undeniably had a major influence in Biomedicine are deployed to help understand and predict the global consequences of ocean acidification. (gu.se)
  • 2003 ). In 2017, the first chromosome-scale reference genome sequence of quinoa was published, and it has provided the much-needed resource for plant biologists to design molecular breeding and crop improvement programs for quinoa (Jarvis et al. (springer.com)
  • https://applications.emro.who.int/dsaf/EMROPUB_2017_EN_19612.pdf. (who.int)
  • Epidemiology Group (GEP) is to including in silico, expression, and work over the 2016-2017 biennium are contribute to understanding the causes sequencing studies, which are often described here. (who.int)
  • The first DNA sequences were obtained in the early 1970s by academic researchers using laborious methods based on two-dimensional chromatography. (wikipedia.org)
  • Information obtained using sequencing allows researchers to identify changes in genes and noncoding DNA (including regulatory sequences), associations with diseases and phenotypes, and identify potential drug targets. (wikipedia.org)
  • Sequencing enables researchers to determine which types of microbes may be present in a microbiome, for example. (wikipedia.org)
  • The researchers also uncovered correlations between specific gene sequences and fruit traits, such as acidity levels, and a gene governing a plant hormone transporter. (genomeweb.com)
  • Current methods, which use next-generation DNA sequencing to characterize all of the transcripts expressed at a given time (collectively known as the transcriptome), involve an intermediate step where researchers must convert the RNA into complementary DNA (cDNA) so that the current sequencing machines can read it. (genome.gov)
  • The new ability to directly sequence the RNA will allow researchers to tackle an entirely new set of experiments. (genome.gov)
  • Thousands of researchers in government, biotech, pharmaceutical and academic labs use Seven Bridges, including three of the largest genomics projects in the world: U.S. National Cancer Institute's Cancer Genomics Cloud pilot, the Million Veteran Program, and Genomics England's 100,000 Genomes Project. (sevenbridges.com)
  • Led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and by HonorHealth Research and Innovation Institute, an international team of researchers have described in detail the individual cells that comprise the pancreatic cancer microenvironment, a critical step in devising new treatment options for patients with this aggressive and difficult-to-treat disease. (medicalxpress.com)
  • Researchers used a relatively new technique known as single-cell sequencing to genetically identify cell types, and subtypes, that occur in pancreatic tumors , and identify the various cells in the tumor 's stroma, a substance surrounding the tumor that can hide the cancer from the body's immune system. (medicalxpress.com)
  • By Terren Roloff, WSU Spokane SPOKANE, Wash. - Four researchers at Washington State University recently received grants for their next-generation DNA sequencing projects through the Genomics Core Laboratory at WSU Health Sciences Spokane. (wsu.edu)
  • SPOKANE, Wash. - Researchers across Washington State University will learn about studying gene expression via RNA sequencing at free workshops June 2 at WSU Pullman and June 3 at WSU Spokane. (wsu.edu)
  • The 2016 peace deal makes it possible for researchers to undertake new bio-expeditions. (eurekalert.org)
  • This time lag can slow the speed of information in NGS-based research, as projects get put on hold, and researchers wait to get their sequencing data. (bio-itworld.com)
  • The first "complete" human genome sequence was actually complete only in terms of what researchers could achieve with the technology available at that time. (jax.org)
  • It's therefore fitting that researchers leading the long read innovation charge at institutions around the country came to JAX for its recent long read sequencing workshop , including some of the leaders of the T2T effort. (jax.org)
  • For Single Cell sequencing the unit operates a 10X Genomics Chromium controller and the new Chromium X capable of high-throughput experiments. (gulbenkian.pt)
  • Nanopore sequencing with Oxford Nanopore Technologies (ONT) systems enables high-throughput long-read sequencing of both DNA and RNA samples. (gulbenkian.pt)
  • High-throughput sequencing (NGS/HTS) now enables the deep sequencing of a lymphoid population with dedicated Rep-Seq methods and softwares. (github.com)
  • Salmonella serotype determination utilizing high-throughput genome sequencing data. (cdc.gov)
  • Exploiting the functional genomics and bioinformatics studies paved the way in understanding the relationship between genotype and phenotype of an organism suffering from environmental stress. (intechopen.com)
  • Humans have been mapping the world for several millennia, but genomes have been mapped and explored for just a single century with the greatest advancements in making a sequence reference map of the human genome possible in the past 30 years. (scienceblogs.com)
  • A reference genome sequence is a map that provides the essential coordinate system for annotating the functional regions of the genome and comparing differences between individuals' genomes. (scienceblogs.com)
  • The rapid speed of sequencing attained with modern DNA sequencing technology has been instrumental in the sequencing of complete DNA sequences, or genomes, of numerous types and species of life, including the human genome and other complete DNA sequences of many animal, plant, and microbial species. (wikipedia.org)
  • Sequencing is used in molecular biology to study genomes and the proteins they encode. (wikipedia.org)
  • Our revolutionary sequencing technologies combine the completeness of long reads with the accuracy of short reads to provide the most comprehensive view of genomes, transcriptomes, and epigenomes. (pacb.com)
  • Reducing assembly complexity of microbial genomes with single-molecule sequencing. (speakerdeck.com)
  • Fabric Genomics' analytic capabilities begin with raw data analysis and include the delivery of rapid, comprehensive insights for high throughout panels, exomes, and whole genomes. (businesswire.com)
  • In the United Kingdom, Genomics England seeks to assess the feasibility, benefits, and risks of whole genome sequencing as part of the Newborn Genomes Programme , an analysis of 100,000 newborn genomes. (medscape.com)
  • Although France's initiative for genomic medicine, France Génomique 2025, does not envisage a neonatal genome sequencing screening program, a team in Dijon is studying several dozen genomes to determine the medical and financial benefits of such a program, explained Geneviève. (medscape.com)
  • The consistent and unambiguous description of sequence variants is essential to report and exchange information on the analysis of a genome. (nih.gov)
  • Single-molecule reads that span the entire genome can capture species without an existing reference sequence as well as detect variants within a particular species. (jax.org)
  • In this study, the complete genomic sequence of Fusarium equiseti D25-1 was determined using multiple sequencing platforms. (researchsquare.com)
  • Shortly after the recent Zika virus outbreak emerged in eastern Brazil, Dr. Richard Scheuermann and his bioinformatics team at JCVI collaborated with software engineers at Northrop Grumman to develop a custom Zika website portal to provide genomic sequence and other data about Zika virus through the public Virus Pathogen Resource (ViPR). (jcvi.org)
  • To support comparative genomics analysis to investigate the evolution of virulence in the newly emerging outbreak isolates, Scheuermann's group developed an algorithm for predicting the proteolytic cleavage sites that generate Zika mature peptides, and applied this method to produce a comprehensive record of all predicted mature peptides for all Zika genomic sequence in the ViPR database. (jcvi.org)
  • However, compared to other flaviviruses, USUV has received less research attention and there is therefore limited access to whole-genome sequences and also to in-depth phylogenetic and phylodynamic analyses. (frontiersin.org)
  • Even the best short read whole genome sequences aren't whole. (jax.org)
  • With emphasis on MinION Nanopore sequencing, cDNA-direct and target-enrichment (amplicon-based) sequencing approaches were validated in parallel. (frontiersin.org)
  • These projects focus on a variety of issues in nucleic acid sequencing such as work focused on direct RNA sequencing to further improvements on nanopore-based sequencing of DNA. (genome.gov)
  • Strategic framework for strengthening health laboratory services 2016-2020. (who.int)
  • She worked in the laboratory and was primarily responsible for the genome sequencing of over 300 beef bulls that significantly contributed their genetics to breeding today. (neogen.com)
  • When Delta Genomics spun out of the University of Alberta to become a private laboratory in 2014, Michelle was promoted to Director of Operations and was responsible for overseeing all laboratory processes and to ensure that everything was running smoothly, on time, and within budget. (neogen.com)
  • The Jackson Laboratory (JAX) has considerable expertise in long read sequencing, and many faculty members rely on it for their research. (jax.org)
  • Building on this momentum, it is critical to · Conduct advocacy at all levels nationally to strength- increase attention to improvements in health laboratory en coordination and integration of laboratory servic- systems and the quality of services provided. (who.int)
  • Adopt the SLMTA approach in implementing quality since 2016 when the regional strategic framework for management systems with established laboratory strengthening health laboratory services 2016-2020 (3) accreditation processes. (who.int)
  • It was initiated in 2014, went into "production" phase in 2015-01-01, and ended 2016-06-23 after it had been announced 2016-01-21 that another laboratory should perform the analyses in question. (lu.se)
  • Complete genome sequence and comparative genomics of a novel Myxobacterium Myxococcus hansupus. (pacb.com)
  • Comparative genomics of Campylobacter fetus from reptiles and mammals reveals divergent evolution in host-associated lineages. (cdc.gov)
  • The reference genome sequence is always product of understanding at a set point in time and continues to evolve. (scienceblogs.com)
  • The current reference genome sequence is a collection of sequences, an assembly, that include sequences assembled into chromosomes, sequences that are part of structurally complex regions that cannot be assembled, patches (fixes) that cannot be included in the primary sequence, and high variability sequences that are organised into alternate loci. (scienceblogs.com)
  • The original reference genome sequence, as well as my own, was generated using short read sequencing technology. (jax.org)
  • The T2T (telomere-to-telomere) consortium announced in late March 2022 that it had generated the first complete, gapless sequence of a human genome. (jax.org)
  • Instead it is an assembly of consensus sequences that are designed to deal with variation in the human population and uncertainty in the data. (scienceblogs.com)
  • DNA sequence data are interpreted through biochemical experiments or comparisons to other DNA sequences. (scienceblogs.com)
  • DNA sequences evolve through duplication and mutation and, as a result, contain many repeated sequences of different sizes, which complicates data analysis. (scienceblogs.com)
  • Others are implementing whole genome or whole exome sequencing as part of biobank efforts linked with electronic health records and/or other epidemiologic data. (cdc.gov)
  • and evidentiary, economic, data sharing and infrastructure, and outcome data requirements needed to implement and measure success of genome sequencing in improving health. (cdc.gov)
  • We determined pili content in silico by aligning short-read WGS data with the sequences of pilus island (PI) 1, PI-2a, and PI-2b and using MOSAIK ( 5 ). (cdc.gov)
  • They analyzed genome sequencing data generated from a collection of 129 peach varieties - including modern cultivars, traditional landraces, and wild peach relatives - and found that genes associated with flavor traits were likely selected by early farmers during the initial domestication of the peach tree in China. (genomeweb.com)
  • September 14, 2016 - CAMBRIDGE, Mass., September 14, 2016 - Seven Bridges , the biomedical data analysis company, today announced that its Cancer Genomics Cloud (CGC) platform is powering the latest DREAM Challenge , focused on accurately identifying cancer-associated rearrangements with RNA sequencing data. (sevenbridges.com)
  • Seven Bridges is the biomedical data analysis company accelerating breakthroughs in genomics research for cancer, drug development and precision medicine. (sevenbridges.com)
  • Fabric Genomics TM is a computational genomics company offering end-to-end genomic data analysis, annotation, curation, classification and reporting solutions to clinical labs, hospital labs, country sequencing programs and life science companies. (businesswire.com)
  • To better understand the karyotype organization in Melipona and the relationship among the subgenera, we mapped repetitive sequences and analyzed previously reported cytogenetic data with the aim to identify cytogenetic markers to be used for investigating the phylogenetic relationships and chromosome evolution in the genus. (karger.com)
  • Vidjil-algo processes high-througput sequencing data to extract V(D)J junctions and gather them into clones . (github.com)
  • The web application can be linked to a sample, experiment and patient database able to store sequencing data and metadata, to run RepSeq software and to save annotations directly from the web application, with authentication. (github.com)
  • Sequencing is a time-consuming process, with runs taking anywhere from hours to days to complete, and it comes on top of the time it takes to prepare the sample and analyze the data. (bio-itworld.com)
  • Scaling is in our DNA: Making Genomics Accessible One of the things I absolutely love about the work we do at Golden Helix is keeping up with the changes in data analysis driven by the iterative and generational leaps in technology. (goldenhelix.com)
  • Work at JCVI is geared toward developing sensitive ZIKV diagnostics, significantly increasing the number of ZIKV genomic sequences available, and performing cutting-edge analysis on current and future sequence data. (jcvi.org)
  • JCVI, through an existing NIH funded grant, is working with the Biodefense and Emerging Infections Research Resources Repository (BEI Resources) to provide high quality sequence data for publically available ZIKV strains. (jcvi.org)
  • For reference, data from a 2016 Victorian Food Consumption study were used to provide expected food consumption frequencies in a healthy population. (who.int)
  • This data set contains seven-day food consumption histories of approximately 500 randomly selected healthy individuals in Victoria from January to April 2016, the same time period as the Salmonella ser. (who.int)
  • 1.2 Links === - BASE (!BioArray Software Environment) is a comprehensive free web-based database LIMS solution for tracking of information and data generated in sequencing and microarray experiments from sample to analysis. (lu.se)
  • The MeLuDI project produced clinical genomics data from samples from patients having specific types of cancer, but also aimed to support cancer research. (lu.se)
  • I address these questions in two steps: firstly, I discuss epistemological implications of the development of Genomics, understood as a data-intensive science, by delving into the theoretical commitments of the concept of gene and the notion of circular causality. (bvsalud.org)
  • In February 2021, scientists reported, for the first time, the sequencing of DNA from animal remains, a mammoth in this instance, over a million years old, the oldest DNA sequenced to date. (wikipedia.org)
  • Single-molecule long-read sequencing has the potential to dramatically advance the field, although high error rates are a challenge with existing methods. (nature.com)
  • To further understand the emergence of serotype IV group B Streptococcus (GBS) invasive disease, we used whole-genome sequencing to characterize 3 sequence type 468 strains isolated from neonates in Minnesota, USA. (cdc.gov)
  • Comparing healthy and mutated DNA sequences can diagnose different diseases including various cancers, characterize antibody repertoire, and can be used to guide patient treatment. (wikipedia.org)
  • As the NIH's only commercial Trusted Partner, Seven Bridges authenticates and authorizes access to one of the world's largest cancer genomics dataset. (sevenbridges.com)
  • Working with our partners and colleagues by utilizing the technology of singe cell sequencing, we can continue to learn more about the biology of pancreas cancer. (medicalxpress.com)
  • 1.3 MeLuDI: The project, and MeLuDI: The software === ==== 1.3.1 The original MeLuDI project 2014 - 2016 ==== "MeLuDI" (short for "melanoma/lung cancer diagnostics") was the name of a project at the Department of Oncology, Clinical Sciences, Lund University. (lu.se)
  • The information is freely available ( https://mitelmandatabase.isb-cgc.org) as an integrated component of the Cancer Genomics Cloud (CGC) - a flexible and powerful platform for cancer genomics research initiated and sponsored by the US National Cancer Institute (NCI). (lu.se)
  • Mitelman F. Cancer gene fusions detected by massive parallel sequencing. (lu.se)
  • Genes Chromosomes Cancer 55:291-310, 2016. (lu.se)
  • Veritas Genetics broke historic ground by making whole genome sequencing and interpretation broadly accessible through myGenome," said Matt Tindall CEO Fabric Genomics. (businesswire.com)
  • According to Diego Martinez, head of bioinformatics, Veritas Genetics, "Fabric Genomics has been a great partner in automating our interpretation pipeline, and making our workflow both seamless and scalable. (businesswire.com)
  • Fabric Genomics and Veritas Genetics have partnered to accelerate Veritas' myGenome product for personal whole genome sequencing using Fabric Annotation. (businesswire.com)
  • Veritas was founded by leaders in genomics from Harvard Medical School and operates globally from its offices in the U.S., Europe and China. (businesswire.com)
  • This is an imperfect copying process that, when combined with short sequencing reads, results in some transcripts being sequenced more easily than others, and in difficulty putting the transcriptome puzzle back together. (genome.gov)
  • We offer long reads lib preparation and sequencing on a MinION instrument (PromethION P2 soon), with either MinION or Flongle flow cells. (gulbenkian.pt)
  • Nearly 10 percent of the genome, including highly repetitive sequences at the ends (telomeres) and middles (centromeres) of chromosomes, remained inaccessible. (jax.org)
  • Casadio, R. I-Mutant2.0: predicting stability changes upon mutation from the protein sequence or structure. (lu.se)
  • Fabric Genomics was founded by scientists and industry pioneers in bioinformatics, large-scale genomics and molecular diagnostics, and is headquartered in Oakland, California with satellite offices in London, Seattle, Salt Lake City and Boston. (businesswire.com)
  • The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. (wikipedia.org)
  • Following the development of fluorescence-based sequencing methods with a DNA sequencer, DNA sequencing has become easier and orders of magnitude faster. (wikipedia.org)
  • DNA sequenced on the Ion Torrent Proton was targeted using the Life Technologies AmpliSeq Exome kit. (claritasgenomics.com)
  • Orthogonal sequencing is available to patients (via their health care providers) in two forms, the Claritas Clinical Exome and Regions of Interest. (claritasgenomics.com)
  • Combining genomics and epidemiology to track mumps virus transmission in the United States. (cdc.gov)
  • Companies that support newer sequencing platforms that promise lower sequencing costs can help alleviate the financial burden. (bio-itworld.com)
  • Each of these platforms have technological limitations due to sample preparation steps, amount of material needed for sequencing, and sequencing depth requirements. (rsc.org)
  • Genomics and Precision Medicine: How Can Emerging Technologies Address Population Health Disparities? (cdc.gov)
  • The most compelling argument for the use of direct RNA sequencing is precision medicine," said Dr. Wanunu, whose award money will be used to overcome some of the challenges associated with direct RNA sequencing. (genome.gov)
  • DNA sequencing is the process of determining the nucleic acid sequence - the order of nucleotides in DNA. (wikipedia.org)
  • Thanks to NHGRI, this program will continue to do wonders in order to improve nucleic acid sequencing technologies. (genome.gov)
  • Species identification of an unknown sample is achieved by comparing its DNA barcode against reference sequences from authenticated specimens of that species. (nature.com)
  • In reality a far longer completion period is more likely because early progress was accelerated by extensive sequence mining from other databases (75% of all records, www.boldsystems.org , May 2016) and natural bias towards the common and least problematic species. (nature.com)
  • The study of structural variation within species and the characterization of the pan-genome has revealed extensive genome content variation among individuals within a species that is paradigm shifting to crop genomics and improvement. (biomedcentral.com)
  • 10 Generade Centre of Expertise Genomics and University of Applied Sciences Leiden, Leiden, The Netherlands. (nih.gov)
  • This study examined the added value of whole genome sequencing (WGS) for investigating a non-point source outbreak of Salmonella ser. (who.int)
  • In February 2016, an increase in Salmonella ser. (who.int)
  • Individuals meeting the case definition were interviewed by phone, beginning 22 February 2016, using a standard Salmonella hypothesis-generating questionnaire to collect demographic, clinical and risk factor information, including travel and food consumption histories during the seven days before illness onset. (who.int)
  • 1.3.2 MeLuDI software 2016- ==== During fall 2016, a number of research projects at Lund University involved lab work using a workflow very close to the one used for the original MeLuDI project, so it was decided that a modified version of the MeLuDI software was to be used to track samples. (lu.se)
  • The authors would like to acknowledge Clinical Genomics Lund, SciLifeLab and Center for Translational Genomics (CTG), Lund University, for providing expertise and service with sequencing and analysis. (lu.se)
  • We found that strains of tetracycline-resistant sequence type 468 GBS have acquired virulence genes from a putative clonal complex 17 GBS donor by recombination. (cdc.gov)
  • Gene coexpression analysis refers to the en masse discovery of coexpressed genes from a large variety of transcriptomic experiments. (mdpi.com)
  • have analyzed the tef-1α sequences of F. equiseti , as well as the toxin-related genes PKS13 , PKS4, and TRI5 [26], and Kari has successfully cloned a protease gene [27]. (researchsquare.com)
  • It can hinder the implementation of wastewater surveillance efforts for detecting infectious disease outbreaks and can become an issue with sequencing-based therapeutics and diagnostics that can create access issues for patients who need them. (bio-itworld.com)
  • Since DNA is an informative macromolecule in terms of transmission from one generation to another, DNA sequencing is used in evolutionary biology to study how different organisms are related and how they evolved. (wikipedia.org)
  • Response to the COVID-19 pandemic has led to the rapid growth of molecular diagnoses and genomic sequencing globally (1,2). (who.int)
  • A link between invasive Group B streptococcus (GBS) infection in humans caused by S. agalactiae serotype III-4, sequence type 283 (ST283) and the consumption of raw fresh-water fish was first described in Singapore in 2015. (bvsalud.org)
  • RNA viruses are more time-sensitive for genome sequencing, as they degrade faster in clinical samples. (wikipedia.org)
  • The companies will co-market the 10x Chromium products and the Qiagen sample handling and prep technologies, and plan to collaborate to develop a comprehensive portfolio of products to improve sample preparation, sequencing, and single-cell biology, 10x said. (genomeweb.com)
  • Primary tumors and core needle biopsies of metastatic lesions from PDAC patients were sequenced using the Chromium single cell RNA-Seq platform. (medicalxpress.com)
  • Knowledge of DNA sequences has become indispensable for basic biological research, DNA Genographic Projects and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematics. (wikipedia.org)
  • To that end, NHGRI is awarding $6.7 million in new research grants to develop DNA sequencing technologies that are more sensitive, faster, cheaper and more accurate than those we already have. (genome.gov)
  • Future research programs can be focused on the development of transgenic plants with enhanced stress tolerance in field conditions based upon the outcome of genomic approaches and knowing the mystery of nucleotides sequences hidden in cells. (intechopen.com)
  • Thermo Fisher Scientific will be there to present the latest sequencing innovations in reproductive genomics research. (thermofisher.com)
  • The project was funded by the Swedish Research Council FORMAS grant number 2016‐00594 and the Oscar and Lili Lamm Foundation grant number FO2018‐0042. (lu.se)
  • Targeted sequencing-like research area-specific panels-can also help reduce costs. (bio-itworld.com)
  • The GemCode technology provides HiSeq X, HiSeq, NextSeq, and MiSeq sequencing users a plug-and-play upgrade to their existing systems, giving them access to a broad range of critical information, and at a much lower cost and a higher quality than other long-read sequencing systems on the market. (genomeweb.com)
  • Sequencing on NextSeq2000 (e.g. 2x150bp PE) or MiSeq (e.g. 2x250bp PE). (gulbenkian.pt)
  • As of September 2016, the ViPR Zika portal contains 389 genomic and 2399 protein sequences representing the three major Zika lineages - East African, West African and Asian. (jcvi.org)
  • In fact, DNA sequencing has become a key technology in many areas of biology and other sciences such as medicine, forensics, and anthropology. (wikipedia.org)