• Exon 9 of the CYP2D6Ch2 gene contained a sequence of 49 bases originating from the pseudogene CYP2D7P. (aspetjournals.org)
  • To evaluate the origin of the detrimental mutation in the genes, parts of the 5' flanking regions were introduced into a Hep G2/simian virus 40 expression system with chloramphenicol acetyltransferase as a reporter gene, and transfected cells were analyzed for activity. (aspetjournals.org)
  • Ser amino acid substitution in a region that is a highly conserved in cytochromes P450 belonging to gene families 1 and 2. (aspetjournals.org)
  • TASY (taxadiene synthase), T5H (taxadiene 5-alpha hydroxylase), TAT (taxadienol acetyltransferase), T10H (5-alpha-taxadienol-10-beta-hydroxylase), T13H (13-alpha-hydroxylase gene), TBT (taxane 2-alpha- O -benzoyltransferase), DBTNBT (3′- N -debenzoyltaxol N -benzoyltransferase), BAPT (phenylpropanoyltransferase), DBAT (10-deacetylbaccatin III-10- O -acetyltransferase) and PAM (phenylalanine aminomutase). (frontiersin.org)
  • A construct containing the bacterial LacZ gene driven by a fragment of the beta-PDE 5' flanking region (-297 to +53) was used to generate transgenic mice. (nih.gov)
  • Photoreceptor-specific reporter gene expression is driven in vivo by a 350-bp segment of the beta-PDE 5' flanking sequence. (nih.gov)
  • This study demonstrates the utility of the human beta-PDE promoter for directing the expression of foreign genes to photoreceptors and suggests that the -297 to +53 beta-PDE 5' flanking region fragment may have important implications for therapeutic gene delivery to the visual cells. (nih.gov)
  • To identify genetic elements that direct appropriate prenatal and postnatal expression of the ADA gene, a segment of DNA including the ADA promoter and 6.4 kilobases of the adjacent 5' flanking region was tested for the ability to direct the expression of a reporter gene in transgenic mice. (utmb.edu)
  • BLAST-able datasets include Cucumis sativus genomic DNA, splice-aligned transcripts and proteins, gene models, and other aligned sequences. (plantgdb.org)
  • The purpose of this resource is to provide a convenient sequence-centered genome view for Cucumis sativus , with a narrow focus on gene structure annotation. (plantgdb.org)
  • The murine alpha-lactalbumin-encoding gene (m alpha La) was isolated and completely sequenced. (eurekamag.com)
  • flanking region indicated the presence of a consensus motif that occurs in all milk-protein-encoding genes, except the kappa-casein-encoding gene. (eurekamag.com)
  • Incorporated into a protein complex named RISC, microRNAs perform posttranscriptional gene regulation either through perfect binding to a cis-regulatory target site in the 3'UTR that is subsequently cleaved, leading to mRNA degradation, or by imprecise binding preferably of the microRNA 5' end to a target site, leading to possibly reversible repression of protein production. (biomedcentral.com)
  • A major challenge in interpreting genome sequences is understanding how the genome encodes the information that specifies when and where a gene will be expressed. (sdbonline.org)
  • Plurality consensus sequences are returned in the main folder and are named after the virus genome or gene segment class label, see the IRMA output page for more details . (cdc.gov)
  • This thesis discusses research conducted to examine the hypothesis that this is due to polymorphisms in the region of the IL-6 gene controlling its expression. (ucl.ac.uk)
  • Single-strand conformational polymorphism analysis of a PCR-generated fragment from the 5' flanking region of the IL-6 gene (-550 to +61) indicated the existence of polymorphisms. (ucl.ac.uk)
  • There is a strong association between a polymorphic repeat sequence in the 5′ flanking region of the gene (avpr1a) encoding one of the AVP receptor subtypes (V1aR), and proneness for monogamous behavior in males of this species. (dericbownds.net)
  • The rate of insulin gene transcription in pancreatic β-cells is regulated by a complex integration of signals derived from nutrients, hormones, and neurotransmitters ( 1 - 5 ). (diabetesjournals.org)
  • Immunoglobulin gene transcription is activated by downstream sequence elements. (wikidata.org)
  • Two DNA probes isolated from the region 5′ to the HLA-B gene are described. (umn.edu)
  • To study the interactions between these sequences and regulatory factors, HeLa cell nuclear proteins were analyzed by band-shift assay using a 95-base pair (bp) DNA probe containing a part of the human MT-IIA gene upstream sequences. (go.jp)
  • In this paper, the (AC)n repeated element located in the 5′ flanking region of the β-globin gene was studied by single-strand conformation polymorphism (SSCP). (wayne.edu)
  • In the present study, genes across the 2q24-q33 interval were analyzed to identify an autism susceptibility gene in this region. (neurotransmitter.net)
  • However, promoter activity of Dax-1 5'-flanking sequences did not require this potential SF-1-responsive element, and Dax-1 expression was unimpaired in knockout mice lacking SF-1, establishing that SF-1 is not required for Dax-1 gene expression in these settings. (duke.edu)
  • Luciferase-containing plasmids are commonly used to investigate the effect of regulatory elements, such as promoters, enhancers and untranslated regions, or the effect of mutations of these regulatory elements on gene expression. (addgene.org)
  • The complete nucleotide sequence of the pertussis toxin gene and the deduced amino acid sequences of the individual subunits have been determined. (justia.com)
  • Besides recombinations with traces limited to the ospC gene itself, there was evidence of lateral gene transfers that involved (i) part of the ospC gene and one of the two flanks or (ii) the entire ospC gene and different lengths of both flanks. (cdc.gov)
  • By means of DNA sequencing of a large sample collection of the pathogen from across the United States, we studied the gene for the bacterium's highly diverse OspC protein, protective immunity against which develops in animals. (cdc.gov)
  • Over time, OspC genes were transferred between strains through recombinations involving the whole or parts of the gene and one or both flanks. (cdc.gov)
  • This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. (wikidoc.org)
  • The nucleotide sequence of the yeast gene TRP5 and its 5' and 3' flanking regions was determined. (unipr.it)
  • To understand the organization of cis-acting sequences that are responsible for oxygen-regulated gene expression, we have studied the 5' flanking region of the mouse gene encoding the hypoxically inducible enzyme lactate dehydrogenase A (LDH). (ox.ac.uk)
  • The gene spans approximately 3.3 kb which includes 791 base pairs of the 5' and 124 base pairs of the 3' flanking regions. (elsevierpure.com)
  • This study describes the molecular cloning of the non-coding exon 1 and approximately 2 kb of 5' flanking region of the human PDGF alpha R gene. (nih.gov)
  • This 5' flanking region is a functional promoter of the PDGF alpha R gene as concluded from its capacity to drive luciferase reporter gene expression in an orientation dependent way. (nih.gov)
  • This effect is mediated through specific transcription factor binding within the -52/+118 region of the PDGF alpha R gene. (nih.gov)
  • Our analysis reveals that in certain areas of an optimized window of Wilms' Tumor gene exon 5 with flanks, a significant correlation exists between regions of structural pairedness and splicing. (columbia.edu)
  • If you have a sequence containing a complete gene, 5'- or 3'-exons, you can use gene structure prediction program FGENEH or exons recognition program FGENEH from the server. (bio.net)
  • We have investigated DA associated genotypes, using candidate gene studies, GWAS and Next Generation Sequencing (NGS) to identify gene variants associated with DA. (cdc.gov)
  • Here we show that the 37-megabase (Mb) genome of A. oryzae contains 12,074 genes and is expanded by 7-9 Mb in comparison with the genomes of Aspergillus nidulans 5 and Aspergillus fumigatus 6 . (nature.com)
  • The blocks of A. oryzae -specific sequence are enriched for genes involved in metabolism, particularly those for the synthesis of secondary metabolites. (nature.com)
  • Sequence analysis revealed two variant CYP2D6 genes, CYP2D6Ch1 and CYP2D6Ch2, having mutations yielding two and eight amino acid substitutions, respectively. (aspetjournals.org)
  • In addition, mutations in the 5' flanking region common to both CYP2D6Ch genes were found. (aspetjournals.org)
  • Sequences of previously described binding sites were collected for these five factors present in the cis-regulatory regions of known target genes. (sdbonline.org)
  • A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes. (wikidata.org)
  • Metallothionein genes are known to be transcriptionally regulated by a variety of factors such as heavy metals, glucocorticoids and cytokines, and have multiple regulatory elements in their 5'-flanking region. (go.jp)
  • Traditional phylogenomic techniques require genome assembly, detection of putative orthologous genes from the assembled sequences, and alignment at the DNA sequence level [ 5 ]. (biomedcentral.com)
  • A 9 base pair (bp) negative cis-regulatory element (NRE) has been identified using band-shift assays employing DNA sequences derived from the 5'-flanking region of HLA class I genes. (nus.edu.sg)
  • The first stage involved identifying, in unrelated subjects showing linkage to 2q24-q33, genetic variants in exons and flanking sequence within candidate genes and comparing the frequency of the variants between autistic and unrelated nonautistic subjects. (neurotransmitter.net)
  • Described are methods and means for the construction and microbial expression of quasi-synthetic genes arising from the combination of organic synthesis and enzymatic reverse transcription from messenger RNA sequences incomplete from the standpoint of the desired protein product. (justia.com)
  • Acquisitions of OspC genes that are novel for the region confer to recipients unique identities to host immune systems and, presumably, selective advantage when immunity to existing types is widespread among hosts. (cdc.gov)
  • Potential T-A-T-A sites for transcription initiation were identified, as well as other sequences that occur frequently in yeast genes. (unipr.it)
  • Nucleic acid sequences involved in regulating the expression of genes. (lookformedical.com)
  • Cis-acting DNA sequences which can increase transcription of genes. (lookformedical.com)
  • but only two of these, an Arg101Stop mutation in exon 2, and an Arg257Cys variation in exon 5, are known to have functional consequences. (aspetjournals.org)
  • Search for any CsGDBgene or aligned sequence by ID or keyword , and download complete sequence or flanking 5' or 3' regions, exons, or introns (FASTA format). (plantgdb.org)
  • The Baylor College Of Medicine Computational Biology Group Houston, TX announces a new service HEXON Prediction of internal exons in Human DNA sequences *************************************************************************** *********** NOTE ADDRESSES AND FORMATS HAVE CHANGED! (bio.net)
  • The recognition quality computed at the level of individual nucleotides is 88% for exons sequences with the level 98% for intron sequences. (bio.net)
  • Phylogeny and evolution of selected primates as determined by sequences of the ɛ-globin locus and 5′ flanking regions. (nature.com)
  • Using CIS-ANALYST, the distribution of Bcd, Cad, Hb, Kr, and Kni binding sites were examined in a 1-Mb genomic region surrounding the well-characterized eve locus at a site_p value of 0.0003. (sdbonline.org)
  • The authors recently mapped a susceptibility locus for autism to chromosome region 2q24-q33 (MIM number 606053). (neurotransmitter.net)
  • Regions still containing the mask have zero coverage and are not necessarily due to deletion events. (cdc.gov)
  • Deletion of the sequence upstream of the AP-1 site (at -283 ~ -277) resulted in loss of this differential response and an overall reduction in expression. (ucl.ac.uk)
  • Analysis of 5' promoter deletion mutants revealed that the region from -441 to +118, relative to the transcription initiation site, is sufficient to establish high level promoter activity. (nih.gov)
  • Three independently derived transgenic lines were generated carrying the -297 to +53 beta-PDE 5' flanking region fragment. (nih.gov)
  • The fragment contains the transcribed region plus 11.5 kb 5'-flanking and 5.5 kb 3'-flanking sequences including all known cis-regulatory elements and the 5' and 3' attachment elements (A-elements) which define the borders of the DNase I sensitive chromatin domain. (eur.nl)
  • The binding sequences for each factor were aligned by using the motif-assembly program, and the binding specificities of each factor were modeled with position weight matrices (PWMs). (sdbonline.org)
  • PWMs are a useful way to represent binding specificities and provide a statistical framework for searching for novel instances of the motif in genome sequences (Berman, 2002). (sdbonline.org)
  • In addition to a TATA box at position -29 relative to the transcription initiation site and two Spl GGGCGG recognition sequences at nucleotide positions -42 to -37 and -50 to -45, the promoter contains a sequence motif matching the transcription activating factor AP-1. (elsevierpure.com)
  • This lack of increase contrasts with previous reports as does the mRNA length: this is 50% larger as confirmed by sequencing the 3' end. (embl.de)
  • All five subunits are coded by closely linked cistrons and possibly expressed through a polycistronic mRNA, since a promotor-like structure was found in the 5' flanking region. (justia.com)
  • S1 nuclease mapping was used to identify three major mRNA transcripts with different 5' termini. (unipr.it)
  • Developments have been made in mRNA secondary structure prediction programs that use thermodynamics to construct possible structural models of mRNA sequences (Seetin and Mathews 2012). (columbia.edu)
  • CAGG) repeat tract and the flanking sequence, as well as genetic selection assays may reveal the mechanisms responsible for the repeat instability in E. coli, and this may lead to a better understanding of the mechanisms contributing to the human disease state. (tmc.edu)
  • A part of the upstream region of base pairs -1407 to -1068 was found to constitute an enhancer element, but the CYP2D6Ch-specific mutations did not influence the chloramphenicol acetyltransferase activity in the expression system. (aspetjournals.org)
  • 5 , 6 In concordance with the role of nodal cilia in L-R asymmetry, mutations in the motor proteins Kif3A and Kif3B, and the transcription factor Foxj1 in the mouse have demonstrated that ciliary motility is important for L-R asymmetry. (bmj.com)
  • For any specified genomic region , download genomic DNA (FASTA format), all aligned/computed transcripts or proteins (FASTA format), or all genome annotations (GenBank, GFF3 or EMBL format). (plantgdb.org)
  • Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins. (wikidata.org)
  • HPV 16/18 infection was detected by nested-polymerase chain reaction (nested-PCR), the p53 mutation was detected by direct sequencing, and the p53 and the HPV 16/18 E6 proteins were studied using immunohistochemistry on 129 pterygial specimens and 20 normal conjunctivas. (molvis.org)
  • A method for determining the sequence specificity of DNA-binding proteins. (lookformedical.com)
  • The genome of Aspergillus oryzae , a fungus important for the production of traditional fermented foods and beverages in Japan, has been sequenced. (nature.com)
  • Sequencing of the A. oryzae genome was accomplished using the whole-genome shotgun (WGS) approach. (nature.com)
  • Syntenic analysis of the three aspergilli revealed the presence of syntenic blocks and A. oryzae -specific blocks of sequence (lacking synteny with the two other aspergilli) in a mosaic manner throughout the A. oryzae genome ( Fig. 1 ). (nature.com)
  • Phylogenetic analysis of the three aspergilli using the whole-genome data showed that A. nidulans branched off earlier than A. oryzae and A. fumigatus 5 . (nature.com)
  • Thus, the increase in genome size seems to be due to an A. oryzae lineage-specific acquisition of sequence, rather than loss of sequence in A. nidulans and A. fumigatus . (nature.com)
  • This suggests that the genome size differences are largely due to sequence acquisition in A. oryzae . (nature.com)
  • Sequence analysis tools accessed from the Genome Context View menu use the current genomic region as input. (plantgdb.org)
  • To study the genomic divergences among hominoids and to estimate the effective population size of the common ancestor of human and chimpanzee we selected 53 autosomal intergenic noncoding DNA segments from the human genome and sequenced them in a human, chimpanzee, gorilla, and orangutan. (ncl.edu.tw)
  • The first step in this process is the identification of regions of the genome that contain regulatory information. (sdbonline.org)
  • Next-generation sequencing technologies are rapidly generating whole-genome datasets for an increasing number of organisms. (biomedcentral.com)
  • To greatly simplify the analysis, we present an Assembly and Alignment-Free (AAF) method ( https://sourceforge.net/projects/aaf-phylogeny ) that constructs phylogenies directly from unassembled genome sequence data, bypassing both genome assembly and alignment. (biomedcentral.com)
  • Our AAF method opens up phylogenomics for species without an appropriate reference genome or high sequence coverage, and rapidly creates a phylogenetic framework for further analysis of genome structure and diversity among non-model organisms. (biomedcentral.com)
  • Most phylogenies are reconstructed from a tiny portion of the genome [ 2 ], but as next-generation sequencing technologies become faster and cheaper, the number of species for which whole genome sequence data are available has increased dramatically. (biomedcentral.com)
  • Repeated sequences are dispersed along the human genome. (wayne.edu)
  • A 5' flanking region of TRP5 was shown by DNA/DNA hybridization to be present in multiple copies in the yeast genome. (unipr.it)
  • A portion of the connecting region of yeast tryptophan synthase exhibits nucleotide sequence similarity to the 3' terminus of E. coli trpC and the trpC-trpB intercistronic region. (unipr.it)
  • Primer extension experiments demonstrated the existence of two possible transcription initiation sites at nucleotide -29 and 32 position, 5' to the start of the translation. (elsevierpure.com)
  • We also found an A + T rich region between nucleotide -505 and -390 which contained twenty-two AAAAT tandem repeats. (elsevierpure.com)
  • It is also called nucleotide sequence. (lookformedical.com)
  • Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories. (lookformedical.com)
  • In this study the cell specificity and expression pattern conferred by the short beta-PDE 5' flanking sequence in vivo were examined. (nih.gov)
  • By using published DNA binding specificity data for five transcription factors active in the early Drosophila embryo, genomic regions containing unusually high concentrations of predicted binding sites were identified for these factors. (sdbonline.org)
  • The other protein appears to be Spl, based on its recognition sequences specificity. (go.jp)
  • In addition, we sequenced 99 ospC flanking sequences from different lineages and compared the complete cp26 sequences of 11 strains as well as the cp26 bbb02 loci of 56 samples. (cdc.gov)
  • Based on a previous GWAS study, 14 DA associated loci and flanking regions were selected for NGS (6,996,180 base pairs). (cdc.gov)
  • Subsequently, truncation and mutation of a vimentin promoter demonstrated that HDAC1‑induced vimentin expression was dependent on a nuclear factor κ‑light‑chain‑enhancer of activated B cells (NF‑κB) binding site in the vimentin promoter sequence. (spandidos-publications.com)
  • The derived amino acid sequence of Ov-phy-1 encoded a peptide that was most similar to the two Caenorhabditis elegans prolyl 4-hydroxylase homologues and to the isoform II enzymes of vertebrates. (embl.de)
  • The plurality consensus sequence is very useful when used with the BAM file to look at minor variants, since the most frequent allele will appear in the reference. (cdc.gov)
  • The ability of the upstream regions to bind nuclear factors was also evaluated using gel-shift analysis. (aspetjournals.org)
  • One of these, pCH6, detects a TaqI polymorphism which is correlated with serological alleles of HLA-B. Both probes are used to show a high level of DNA sequence homology between the 5′ flanking region of HLA-B and HLA-C. (umn.edu)
  • Two compounds, Compound 1 (1,4-dihydrophenanthrolin-4-one-3-carboxylic acid) and Compound 5 [8-(N-butyl-N-ethylcarbamoyl)-1,4-dihydrophenathrolin-4-one-3-carboxylic acid], with comparable potencies in vivo, were chosen to investigate the effect of the inhibition of the hydroxylation of newly synthesized uterine collagen on the turnover of this protein in vivo. (embl.de)
  • All sequences which adopt a DNase I hypersensitive chromatin conformation in vivo are present on the construct. (eur.nl)
  • Expressed sequence tag (EST) analysis and developmental polymerase chain reaction (PCR) studies demonstrated that Ov-phy-1 was expressed in L3 and adult parasites. (embl.de)
  • Method description: ********************** The method is based on the discriminant analysis of open reading frames flanked by GT and AG base pairs. (bio.net)
  • Analysis of transcription factor (TF) and ChIP- seq datasets identified overlap of 70 SNPs with TF binding regions of relevant lung cell lines (e.g. (cdc.gov)
  • Small domestic ruminant breeding is an activity of great economic and social importance, especially in regions of countries with arid and semiarid climates (Silva et al. (bvsalud.org)
  • 2006). In north eastern Brazil these animals are quite rustic, adapted to conditions of arid and semiarid regions and, therefore, have adapted to environments where arid climatic conditions and topographical limitations are dominant, such as mountainous areas (Silva et al. (bvsalud.org)
  • We identify the main binding sites of a catalytically inactive Cas9 (dCas9) protein in bovine fetal fibroblast cells (BFFs) with chromatin immunoprecipitation sequencing (ChIP-seq). (biomedcentral.com)
  • Empty backbones for inserting regulatory elements before or after the luciferase ORF can be found in a table below, as well as plasmids that already contain a region of interest before or after luciferase . (addgene.org)
  • We identified 34 visual behaviours, which were grouped into eight categories according to their functional character: food = 4), social interaction (n = 6), displacement (n = 2), resting (n = 3), grooming (n = 4), neutral position (n = 3), bipedal (n = 5) and other activities (n = 7). (bvsalud.org)
  • Prediction is performed by linear discriminant function combining characteristics describing donor and acceptor splice sites, 5'- and 3'-intron regions and also coding region for each open reading frames flanked by GT and AG base pairs. (bio.net)
  • Short-term activation of protein kinase C by 5 min exposure to PMA caused an acute increase in Na/H antiporter activity that was not prevented by cycloheximide or actinomycin D and did not persist 24 h later. (jci.org)
  • namely, this protein is activated only by Zn, and requires not only MRE but also its flanking sequences for optimal DNA-binding. (go.jp)
  • The majority of the alignment-free methods focus on the distribution within and among study genomes of short DNA/protein fragments, known generally as k- mers where k is the length of the substring taken from the original sequences [ 15 ]. (biomedcentral.com)
  • The blue bars at the bottom indicate the regions syntenic with A. fumigatus ( AF ) and A. nidulans ( AN ) genomes (see Methods). (nature.com)
  • Using mathematical calculations, models of sequence evolution, and simulated sequencing of published genomes, we address both evolutionary and sampling issues caused by direct reconstruction, including homoplasy, sequencing errors, and incomplete sequencing coverage. (biomedcentral.com)
  • The two segments are joined by a connecting region of 28 residues in the yeast enzyme which is not homologous to either the alpha or beta chains of the bacterial enzyme. (unipr.it)
  • DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. (lookformedical.com)
  • L'article présente les données collectées, depuis le commencement du programme en janvier 1995 jusqu'en décembre 2011, sur l'incidence des troubles dépistés ainsi que la base moléculaire des cas positifs dépistés. (who.int)
  • The DM2 repeat tract contains a flanking region 5' to the tract that consists of a polymorphic repetitive sequence (TG)14-25(TCTG)4-11(CCTG) n. (tmc.edu)
  • Glucose and GLP-1 also synergistically activated NFAT (nuclear factor of activated T-cells)-mediated transcription from a minimal promoter construct containing tandem NFAT consensus sequences. (diabetesjournals.org)
  • La spectrométrie de masse en tandem, les technologies moléculaires et l'analyse biochimique ont été utilisées pour les besoins du dépistage. (who.int)
  • Approximately 10 µg of total DNA from the algal culture (ITS sequence GenBank JF831923) was used to construct a library (sheared DNA fragments were of 500 bp length) for 100 bp × 100 bp paired-end sequencing using an Illumina GAIIx and standard Illumina protocols (Illumina, San Diego, California, USA). (bioone.org)
  • Sequence variations that affect CYP2A13 expression may contribute to interindividual differences in susceptibility to tobacco-related tumorigenesis. (aspetjournals.org)
  • However, the cis-regulatory sequence controlling this posterior expression pattern has not been precisely identified. (sdbonline.org)
  • The slightly earlier onset of SF-1 expression and its ability to bind specifically to a conserved sequence in the Dax-1 5'-flanking region suggested that SF-1 may activate Dax-1 expression. (duke.edu)
  • Preferred products of expression lack bio-inactivating leader sequences common in eukaryotic expression products but problematic with regard to microbial cleavage to yield bioactive material. (justia.com)
  • The average sequence divergence was only 1.24% ± 0.07% for the human-chimpanzee pair, 1.62% ± 0.08% for the human-gorilla pair, and 1.63% ± 0.08% for the chimpanzee-gorilla pair. (ncl.edu.tw)
  • These sequences are useful as markers in diagnosis of inherited diseases, in forensic medicine, and in tracking the origin and evolution of human populations. (wayne.edu)
  • A rodent epithelioid cell transformed with a recombinant DNA vector including a DNA sequence encoding human erythropoietin, the transformed cell being capable of producing N-linked and O-linked glycosylated human erythropoietin. (justia.com)
  • The final plurality consensus and the final reference are the same sequence! (cdc.gov)
  • These sequences are modifications to the plurality consensus. (cdc.gov)
  • It can be useful to differentiate these regions from deletions in the amended consensus. (cdc.gov)
  • The most important of these, although not capable of driving hypoxic induction in isolation, had the consensus of a hypoxia-inducible factor 1 (HIF-1) site, and cross-competed for the binding of HIF-1 with functionally active Epo and phosphoglycerate kinase-1 sequences. (ox.ac.uk)
  • In physiologic jaundice, the peak total serum bilirubin level is 5-6 mg/dL (86-103 µmol/L), occurs at 48-120 hours of age, and does not exceed 17-18 mg/dL (291-308 µmol/L). (medscape.com)
  • Methods We performed whole exome sequencing in a consanguineous family with heterotaxia. (bmj.com)
  • Our model does not rely on evolutionary conservation, which allows the detection of species-specific interactions and makes TargetSpy suitable for analyzing unconserved genomic sequences. (biomedcentral.com)
  • Goats conduct their daily routine with sequences of behaviour that involve eating (food intake or selection) and resting or ruminating, with social interactions and other activities having happened more frequently in the afternoon and at that time in the afternoon before being provided with food. (bvsalud.org)
  • Spliced alignment of user-specified transcript datasets to genomic DNA from any region in CsGDB. (plantgdb.org)
  • As a test case with real data, we successfully reconstructed the phylogeny of 12 mammals using raw sequencing reads. (biomedcentral.com)
  • may also be facilitated by a Harvey sarcoma virus enhancer sequence. (justia.com)
  • The second domain was positioned close to the HIF-1 site, in an analogous position to one of the critical regions in the Epo 3' hypoxic enhancer. (ox.ac.uk)
  • The SAM file is processed and deleted regions spanned by reads are restored to deletions. (cdc.gov)