AnatomyOrganismsChemicals and DrugsPhenomena and ProcessesTechnology, Industry, AgricultureInformation Science
TyrothricinPeptide SynthasesGramicidinBacillusFormamidesTyrocidineCetomacrogolThiolester HydrolasesPantetheineSpores, BacterialMicrococcal NucleaseDimethyl SulfoxideAnti-Bacterial AgentsTranscription, GeneticAmino Acid SequenceStructure-Activity RelationshipMolecular Sequence Data
GramicidinAnalogues
Gramicidin5
  • Tyrocidine is the major constituent of tyrothricin, which also contains gramicidin. (wikipedia.org)
  • Tyrothricin was later found to be a mixture of the peptides gramicidin and tyrocidine. (wikipedia.org)
  • The biosynthesis of Tyrocidine is similar to Gramicidin S, and is achieved through the use of nonribosomal protein synthetases (NRPSs). (wikipedia.org)
  • Using protoplasts & macrophages permits synchronised experiments (not possible in whole organisms/tissues) to compare temporal changes in plant and animal cells following cocultivation with WT and T3SS-defective Pseudomonas & Salmonella, and exposure to the respective (PopB/D:PcrV & SipB/SipC) pore-forming T3SS components & ionophore controls (gramicidin & tyrocidine). (ukri.org)
  • The genes involved in antibiotic production have been well characterized and have led to the commercial production of tyrocidine and gramicidin. (up.ac.za)
Analogues1
  • The different tyrocidine analogues (A-D) are not produced by different enzymes, but rather by an enzyme system that is capable of incorporating different amino acids of structural similarity at specified sites. (wikipedia.org)