Salivary gland 1998 carcinoma adenoid cystic. Medical search. Frequent questions

BACKGROUND AND PURPOSE: This study aimed to investigate the immunohistochemical expression of CD31 and podoplanin in order to examine angiogenesis and lymphangiogenesis, respectively in common malignant tumors of salivary glands. (bvsalud.org)
CONCLUSION: The higher level of angiogenesis and lymphangiogenesis in mucoepidermoid carcinoma, specifically at the center of tumor, compared to adenoid cystic carcinoma, may be attributed to differences in the clinical behaviors and metastasis of tumors. (bvsalud.org)
Skálová A., Leivo I., Michal M., Saksela E. Analysis of collagen isotypes in crystalloid structures of salivary gland tumors. (biopticka.cz)
Skálová A., Leivo I. Extracellular collagenous spherules in salivary gland tumors. (biopticka.cz)
Skálová A: Cell proliferation in salivary glands and tumors of salivary gland origin. (biopticka.cz)
In a series of 175 human adult tumors, gene expression was highest in ovarian serous carcinomas. (nature.com)
Transplanted cells in nude mice formed subcutaneous tumors, which had histological features of squamous cell carcinoma with apparent keratinizing tendencies. (biomedcentral.com)
Aim: The aim of this study is to investigate the DNA ploidy and S-Phase Fraction (SPF) of some Salivary Gland Tumors (SGTs) in Egyptian patients and to investigate the correlation between these two biological parameters and the presumptive behavior of these neoplasms. (researchgate.net)
Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
Squamous cell carcinoma (SCC) in various morphological forms needs to be separated from other epithelial tumors for treatment modality selection. (cytojournal.com)
The nuclear expression of β-catenin is considered a characteristic feature of BCA because other salivary gland tumors rarely show nuclear staining [ 2 ]. (biomedcentral.com)
Epithelial salivary gland neoplasms are rare both in adults and children, accounting for less than 3% of all head and neck tumors. (9lib.co)

Skálová A, Leivo I, Boguslawsky K, Saksela E: Cell proliferation correlates with prognosis in acinic cell carcinomas of salivary gland origin. (biopticka.cz)
The malignant tumours consisted of 18 adenoid cystic adenomas, 10 mucoepidermoid carcinomas, 5 acinic cell carcinomas, 5 carcinoma in pleomorphic adenoma as well as of 12 other malignancies belonging to 7 different tumour entities. (researchgate.net)
Abnormal DNA content has been related to aggressive behavior in Mucoepidermoid Carcinomas (MEC), Adenoid Cystic Carcinomas (AdCC), Acinic Cell Carcinomas (ACC) and oncocytomas (Onc) [8]. (researchgate.net)

They are predominantly found in the parotid gland and represent approximately 1% of salivary gland tumours. (wikipedia.org)
Are adenomyoepithelioma of the breast and epithelial-myoepithelial carcinoma of the salivary glands identical tumours? (wikipedia.org)
This study investigates whether salivary tumours with different morphology and evolution also differ in terms of neovascularization and VEGF expression and the prognostic value of the results. (bvsalud.org)
Surgical specimens from 45 patients - 8 pleomorphic adenomas (PA), 7 Warthin tumours (WT), 5 basal cell adenomas (BA), 6 carcinomas ex-pleomorphic adenoma (CEPA), 6 mucoepidermoid carcinomas (MEC), 5 acinic cell carcinomas (AC), 4 adenoid cystic carcinomas (ACC) and 4 adenocarcinomas not otherwise specified (ADK NOS) - were immunostained. (bvsalud.org)
In malignant salivary tumours, the following mean microvascular density (MVD) values were recorded (± SD = Standard Deviation): 27.61 (SD ± 2.27) in cases with CEPA, 27.08 (DS ± 7.81) in AC and 32.93 (SD ± 7.76) in ADK NOS, with lower values for MEC 24.31(SD ± 2.88) and for ACC 22.13 (SD ± 5.44). (bvsalud.org)
The VEGF expression is significantly more important (p = 0.001) in malignant salivary tumours as compared with benign ones. (bvsalud.org)
The VEGF expression and the microvascularization in salivary gland tumours are important elements to be considered when formulating a diagnosis and assessing case evolutions in patients with such tumours. (bvsalud.org)
Skálová A, Leivo I. Basement membrane proteins in salivary gland tumours. (biopticka.cz)
MEC is an extremely rare tumour of the minor salivary glands, accounting for less than 1% of tumours of this origin [3]. (cyberleninka.org)
This study on 279 tumours of the salivary glands was conducted to analyse whether the assessment of DNA ploidy by flow cytometry may assist histopathology in discriminating benign from malignant types of tumours. (researchgate.net)
Twelve of 50 malignant salivary gland tumours were aneuploid. (researchgate.net)
The most obvious value of DNA flow cytometry in salivary gland tumours is thus its contribution to assist histopathology in identifying potentially malignant lesions. (researchgate.net)
Another change is the subclassification of adenocarcinoma: the definition of bronchioalveolar carcinoma has been restricted to noninvasive tumours. (ersjournals.com)

Pleomorphic adenomas occur most often in the parotid gland, with a predilection for the tail of the superficial lobe (70-80% of cases). (medscape.com)
Pleomorphic adenomas in the deep lobe of the parotid gland may present as an oral retrotonsillar mass or parapharyngeal space tumor. (medscape.com)
Skálová A., Michal M. Epimyoepithelial carcinoma of parotid gland. (biopticka.cz)
Skálová A, Michal M: Biphasic myoepithelioma of parotid gland with collagenous crystalloids. (biopticka.cz)
We have established five cell systems from a benign pleomorphic adenoma of the parotid gland of a 61-year-old woman. (biomedcentral.com)
We established and characterized five cell systems (designated as SM-AP1 to SM-AP5) from a benign pleomorphic adenoma of the parotid gland. (biomedcentral.com)
MEC mainly occurs in the parotid gland, along with minor glands being the second common site, particularly in palate. (9lib.co)
When MEC appears as asymptomatic swellings in minor salivary glands, being the second most common site of occurrence after the parotid gland, it can be located on palate, in retromolar area, floor of mouth, buccal mucosa, lips, and tongue [2-5]. (9lib.co)

Epithelial-myoepithelial carcinoma (EMCa) is a rare malignant tumour that typically arises in a salivary gland and consists of both an epithelial and myoepithelial component. (wikipedia.org)
Epithelial-myoepithelial carcinoma of the salivary gland--a low grade malignant neoplasm? (wikipedia.org)
Michal M, Skálová A, Simpson RHW, Rychterová V, Leivo I: Clear cell malignant myoepithelioma of the salivary glands. (biopticka.cz)
It is still poorly understood how and which benign pleomorphic adenoma cells transform into its malignant form, carcinoma ex pleomorphic adenoma. (biomedcentral.com)
Basal cell adenoma (BCA) and basal cell adenocarcinoma (BCAC) are benign and malignant, basaloid salivary gland neoplasms, respectively. (biomedcentral.com)
The malignant lesions comprised three cases of ductal carcinoma in situ (DCIS) and 22 cases of infiltrating ductal carcinoma, not otherwise specified, IDC (NOS). (ijpmonline.org)

Pleomorphic adenomas of the minor salivary glands comprise only 5-10% of cases, with the palate (particularly the junction of the soft and hard palate) and the lip being the most common sites. (medscape.com)
This study aimed to evaluate and compare the immunoexpression of glucose transporter-1 (GLUT-1) and angiogenic index between pleomorphic adenomas (PAs), adenoid cystic carcinomas (ACCs), and mucoepidermoid carcinomas (MECs) of the salivary glands, and establish associations with the respective subtype/histological grade. (bvsalud.org)

of esophageal squamous cell carcinoma [10]. (cyberleninka.org)
The histological features of squamous cell carcinoma from the transplanted cell systems in nude mice might suggest a secondary onset of malignancy from a pre-existing benign adenoma. (biomedcentral.com)
Other studies in oral cancer [23,24] reported that there is no relationship between the histopathological grade of oral epithelial dysplasia or oral squamous cell carcinoma and the ploidy status. (researchgate.net)
Correction: Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck. (mdanderson.org)
Outcomes after radiation therapy for T2N0/stage II glottic squamous cell carcinoma. (mdanderson.org)

Skálová A, Lehtonen H, Boguslawsky K, Leivo I: Prognostic significance of cell proliferation in mucoepidermoid carcinomas of salivary gland. (biopticka.cz)
There was no significant correlation of ploidy status or SPF with the tumor grades of mucoepidermoid carcinomas. (researchgate.net)

Pleomorphic adenoma is the most common salivary gland tumor in both children and adults, accounting for 45-75% of all salivary gland neoplasms. (medscape.com)
Mucoepidermoid carcinoma (MEC), one of the most common salivary gland malignancies, is rare in children. (9lib.co)

18 With the exception of the ovarian neoplasms, the same carcinomas analyzed for gene expression were also examined for HE4 by immunohistochemistry on tissue microarrays (see below). (nature.com)
Salivary gland carcinoma (SGC) is rare cancer, constituting 6% of neoplasms in the head and neck area. (genominfo.org)
Renal cell carcinoma (RCC) originates from either the cancerous renal cortex or renal tubular epithelial cells, and is the second most lethal urological malignancy, accounting for 90-95% of kidney neoplasms. (biomedcentral.com)

Pleomorphic adenoma is a benign salivary gland tumor that exhibits wide cytomorphologic and architectural diversity. (medscape.com)
Among the salivary gland carcinomas, carcinoma in pleomorphic adenoma has been regarded as a representative carcinoma type which arises secondarily in the background of a pre-existent benign pleomorphic adenoma. (biomedcentral.com)
A basal cell adenoma (BCA) is a benign salivary gland basal cell neoplasm (BCN) that shows a dual-cell proliferation of inner luminal/ductal cells and outer abluminal/ myoepithelial or basal cells [ 1 ]. (biomedcentral.com)

Moreover, considering the high LVD at the center of tumor in mucoepidermoid carcinoma and infrequency of metastasis to regional lymph nodes in adenoid cystic carcinoma, it can play a significant role in metastasis to regional lymph nodes. (bvsalud.org)
Skálová A, Michal M, Nathanský Z : Epidermoid carcinoma arising in Warthin's tumor. (biopticka.cz)
Prognostic significance of tumor cell proliferation rate as determined by the MIB-1 antibody in breast carcinoma: Its relationship with vimentin and p53 protein. (mpg.de)
Nursing based on oxygen administration decreased the value of renal function indexes, serum inflammatory factors, and tumor markers in renal cell carcinoma patients. (biomedcentral.com)

Significant abnormality or disease of the salivary glands, such as that associated with Sjögren syndrome or neoplasm, necessitates additional evaluation by an otolaryngologist or an otolaryngologist/head and neck surgeon for comprehensive treatment of the gland pathology itself. (medscape.com)
In some countries, maxillofacial surgeons are also involved in the primary treatment of neoplasm involving the salivary glands. (medscape.com)
Salivary gland carcinoma (SGC) is an uncommon neoplasm, which constitutes approximately 6 percent of cancers in the head and neck region [ 1 , 2 ]. (genominfo.org)

For three locoregionally advanced oropharyngeal carcinomas and one adenoid cystic carcinoma, mean dose to the contralateral salivary glands, pharynx and oral cavity was reduced by 2.5, 1.7 and 3.1 Gy respectively on average with DTRT compared to VMAT. (biomedcentral.com)

Large cell neuroendocrine carcinoma (LCNEC) is now recognized as a histologically high grade non small cell carcinoma showing histopathological features of neuroendocrine differentiation as well as immunohistochemical neuroendocrine markers. (ersjournals.com)
Among the IDC (NOS) lesions, six cases of grade III breast carcinoma exhibited a positive immunohistochemical reaction, the staining index of which varied from 2-6. (ijpmonline.org)

The parotids produce the most fluid saliva, as they are composed of serous acini, with the sublingual gland producing mucus from mucous acini. (medscape.com)

Rare or unusual sites of occurrence may be attributable to ectopic salivary gland tissue (eg, in the mandible, neck lymph nodes, or axilla). (medscape.com)

p21/WAF 1/Cip 1 expression in invasive ductal breast carcinoma: relationship to p53, proliferation rate, vimentin, cathepsin D and survival at 5 years. (mpg.de)

Methods: Using immunohistochemistry, expression levels of p63 and Ki-67 were determined in 16 myoepithelial carcinoma samples and correlated with clinicopathological characteristics and patient prognosis. (cyberleninka.org)

The histologic differential diagnosis includes adenoid cystic carcinoma and pleomorphic adenoma. (wikipedia.org)
In our previous study, we proposed a concept of focal carcinomas in pleomorphic adenoma which is an advanced stage of accumulated atypical cells with P53 over-expressions as an initial stage or a latent form of apparent carcinomas secondarily arising in pleomorphic adenoma [ 3 ]. (biomedcentral.com)
Examination of consecutive slides actually revealed small assemblies of carcinoma cells that required a final diagnosis as non-invasive carcinoma in pleomorphic adenoma. (researchgate.net)

In addition, p63 and Ki-67 expression levels were associated with myoepithelial carcinoma recurrence and metastasis. (cyberleninka.org)
Conclusions: Recurrence and metastasis in myoepithelial carcinomas are more frequent in p63-positive and Ki-67-positive EMCs, and poor prognosis is associated with overexpression of p63. (cyberleninka.org)
Hypoxia is considered a critical contributor to renal cell carcinoma progression, including invasion and metastasis. (biomedcentral.com)

The large cell carcinoma class has been enriched with several variants, including the LCNEC and the basaloid carcinoma, both with a dismal prognosis. (ersjournals.com)
As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)

Background: Myoepithelial carcinoma is a rare tumour. (cyberleninka.org)
Myoepithelial carcinoma (MEC) is a rare tumour that was first described by Stromayer et al. (cyberleninka.org)

CK 5/6 expression breast carcinoma implies a 'basal like' molecular phenotype and is associated with poor prognosis. (ijpmonline.org)

Approximately 1000 minor glands, localized to the cheeks, lips, and other intraoral mucosa, contribute about 7% to the whole saliva volume. (medscape.com)
Using tissue microarrays and full tissue sections of normal and 448 neoplastic tissues, HE4 immunoreactivity was found in normal glandular epithelium of the female genital tract and breast, the epididymis and vas deferens, respiratory epithelium, distal renal tubules, colonic mucosa, and salivary glands, consistent with HE4 gene expression. (nature.com)

For a locally recurrent nasopharyngeal carcinoma, D 0.03 cc to the ipsilateral optic nerve was above tolerance (54.0 Gy) for VMAT (54.8 Gy) but within tolerance for DTRT (53.3 Gy). (biomedcentral.com)

Carcinoma cervix is not the only cancer caused by HPV. (cytojournal.com)

The submandibular glands produce both serous and mucous saliva. (medscape.com)
The minor glands are primarily mucous producing, except those under the tongue, which produce serous fluid. (medscape.com)

[ 7 ] age-related decline in saliva output was found to occur in the stimulated parotid, unstimulated submandibular/sublingual, and stimulated submandibular/sublingual glands. (medscape.com)
Additional research suggests that changes may occur in the viscoelasticity of saliva with aging, particularly in saliva produced by the submandibular and sublingual glands. (medscape.com)

For a laryngeal carcinoma, DTRT resulted in higher dose than VMAT to the pharynx and brachial plexus but lower dose to the upper oesophagus, thyroid gland and contralateral carotid artery. (biomedcentral.com)

A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. (lookformedical.com)

However, adenocarcinomas of the lung, and occasional breast, transitional cell and pancreatic carcinomas had moderate or high levels of HE4 expression. (nature.com)

Thus, conclusions regarding prognostic factors and ideal treatment may emerge as the number of investigated myoepithelial carcinoma cases accumulate. (cyberleninka.org)

In addition of the categories of squamous dysplasia and carcinoma in situ , two additional lesions were added to the group of pre-invasive lesions: atypical adenomatous hyperplasia (AAH) and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). (ersjournals.com)

From January to December 1998, 482 cases of acute respiratory infections in children attended at the emergence or pediatric wards of Centro Pediátrico Professor Hosannah de Oliveira, of Universidade Federal da Bahia, in Salvador (Brazil), were analysed. (scielo.br)

The results elucidate a mechanism wherein the solute carrier family 14 member 1 gene participates in the occurrence and development of hypoxia-induced renal cell carcinoma in a mitochondria-dependent manner. (biomedcentral.com)

[ 1 ] This article reviews basic salivary anatomy and physiology, several important diseases affecting the glands, salivary constituents as measures of health, trends in diagnosis, and the management of xerostomia and drooling. (medscape.com)

The purpose of this study was to investigate the role and mechanism of hypoxia-induced renal cell carcinoma and provide evidence-based medical proof for improvements to postoperative nursing of renal cell carcinoma patients. (biomedcentral.com)
A total of 64 patients with renal cell carcinoma were divided into the observation group (nursing based on oxygen administration) and the control group (conventional nursing). (biomedcentral.com)

Figure 1: (a) Preoperative intraoral image of a mucoepidermoid carcinoma of the left posterior hard palate with 8 mm diameter and fistula opening (black arrow). (9lib.co)

These data reveal that nursing based on oxygen administration can improve the clinical efficacy of renal cell carcinoma therapies, being safe and effective. (biomedcentral.com)

The human renal cell carcinoma cell line A498 under hypoxia/normoxia was used as an experimental model in vitro and the biological characteristics and mitochondrial function of the cells were assessed. (biomedcentral.com)

HE4 is one of more than 8900 different human genes represented on U95a GeneChips (Affymetrix, Santa Clara, CA, USA), which we used previously to develop a molecular classification of 175 human carcinomas based on patterns of gene expression. (nature.com)

Accordingly, mucoepidermoid carcinoma (MEC) is the most frequent subtype, with more than 30% of the SGC cases, followed by the adenoid cystic carcinoma (ACC) with the pathology in 23.8% of all SGC cases, and the adenocarcinoma not otherwise specified [ 4 ]. (genominfo.org)

Dentists are involved with aspects of salivary gland function in several ways, such as diagnosing problems involving the major and minor salivary glands, in the management of oral dryness associated with salivary problems, in the treatment of caries and periodontal disease resulting from decreased salivary flow, and in controlling salivation during restorative procedures. (medscape.com)
At rest, the parotid glands, located anterior to the ears, produce approximately 25% of oral saliva. (medscape.com)
The sublingual glands, under the tongue, produce about 5% of the total oral saliva. (medscape.com)

The salivary system is composed of 3 major gland sets and multiple minor glands. (medscape.com)
Other sites of minor salivary gland involvement may include the nose, the paranasal sinuses, and the larynx. (medscape.com)

Skálová A, Michal M: Patterns of cell proliferation in actinic keratoacanthomas and squamous cell carcinomas of the skin. (biopticka.cz)

MATERIALS AND METHODS: Forty formalin-fixed, paraffinated blocks (20 adenoid cystic carcinoma and 20 mucoepidermoid carcinoma blocks) were selected from the medical archives of Amir A'lam Hospital of Tehran, Iran. (bvsalud.org)

[ 4 ] Approximately 1-1.5 liters of saliva are produced by the glands in a day. (medscape.com)

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