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  • gene
  • And now that a powerful gene-editing technique has been used on human embryos, it's fine to get a little freaked out. (wired.com)
  • Added world-recognized neurobiologist, Dr. Evan Y. Snyder, head of the FDA's Cellular, Tissue and Gene Therapies Advisory Committee, Director of the Stem Cells and Regenerative Biology Program at Sanford Burnham Medical Research Institute, as an non-compensated member of our Board of Advisors. (marketwired.com)
  • In recent attempts to alleviate the symptoms of t hese d iseases, research has turned to the capabilities of gene therapy as a tool for treatment . (issuu.com)
  • viable
  • Research is needed to determine the most viable stem cell lines and reliable ways to promote the differentiation of pluripotent stem cells into specific cell types (neurons, muscle cells, etc. (jci.org)
  • federally-funded
  • More than 60 existing stem cell lines from genetically diverse populations around the world are expected to be available for federally-funded research. (archives.gov)
  • In August 2010, as part of preliminary motions in Sherley vs Sebelius, Judge Royce C. Lamberth granted an injunction against federally funded embryonic stem cell (ESC) research on the grounds that the guidelines for ESC research "clearly violate" the Dickey-Wicker Amendment. (wikipedia.org)
  • Oak Ridge National Laboratory (ORNL) is an American multiprogram science and technology national laboratory sponsored by the U.S. Department of Energy (DOE) and administered, managed, and operated by UT-Battelle as a federally funded research and development center (FFRDC) under a contract with the DOE. (wikipedia.org)
  • preliminary
  • The Phase I clinical study is a dose escalation safety and preliminary efficacy study of ISC-hpNSC ® , intracranially transplanted into patients with moderate to severe Parkinson's disease. (cnbc.com)
  • clinical
  • IVF pioneer and stem-cell researcher Professor Alan Trounson of the Monash Institute of Reproduction and Development recently told The Sydney Morning Herald that he would like Australia to be the first to conduct clinical trials within two years, and that this would require access to new lines of stem cells from 'spare' IVF embryos. (abc.net.au)
  • Additionally, the safety and efficacy of the treatment must be tested before the therapy can begin to make its way towards clinical development, Turnbull said. (the-scientist.com)
  • Subsequent to the quarter end, in July, 2015, the Company completed a nine month safety study of the hpNSCs demonstrating safety elements for regulatory approval of the upcoming Parkinson's disease clinical trial, and submitted the results to the Australian TGA. (marketwired.com)
  • As with all forms of clinical treatment, the medical community looked to basic science research to improve the safety and efficacy of IVF for mothers and babies. (wikipedia.org)
  • It is recommended only as a third line treatment in graft versus host disease in adults, based on lack of efficacy and side effects observed in clinical trials. (wikipedia.org)
  • Michigan Medicine has nearly 26,000 employees, including about 2,700 faculty, more than 5,000 nurses and nearly 1,200 residents and clinical fellows known as house officers as well as other clinical, research, education and administrative staff. (wikipedia.org)
  • nuclear
  • The laboratory is home to several of the world's top supercomputers including the world's fifth most powerful supercomputer ranked by the TOP500, Titan, and is a leading neutron science and nuclear energy research facility that includes the Spallation Neutron Source and High Flux Isotope Reactor. (wikipedia.org)
  • After the end of World War II the demand for weapons-grade plutonium fell and the reactor and the laboratory's 1000 employees were no longer involved in nuclear weapons, instead it was used for scientific research. (wikipedia.org)
  • treatments
  • With heart failure leading the cause of death in the USA (Hunt), biomedical research is fundamental to advance medical treatments for cardiovascular diseases. (jove.com)
  • Research is underway to develop various sources for stem cells, and to apply stem-cell treatments for neurodegenerative diseases and conditions such as diabetes, heart disease, and other conditions. (wikipedia.org)
  • pregnancy
  • The embryos will be donated by couples undergoing IVF, and current legal restrictions remain in place: the embryos must be destroyed before they are 14 days old, and it will be illegal to use them to achieve a pregnancy. (phgfoundation.org)
  • study
  • Drug high-throughput screening Cerebral organoids can be used as simple models of complex brain tissues to study the effects of drugs and to screen them for initial safety and efficacy. (wikipedia.org)
  • demonstrate
  • While the primary endpoint of the trial is to demonstrate safety, doctors are also testing whether the cells restore sensation and movement. (cellmedicine.com)
  • Published the results of two proof of concept studies that demonstrate the safety and efficacy of the Company's stem cell treatment of Parkinson's disease in both non-human primate and rodent animal models in the journal " Cell Transplantation" . (marketwired.com)
  • treatment
  • While research into the treatment of blood and immune disorders is promising, there are many hurdles to be overcome surrounding the safety and efficacy of these techniques. (phgfoundation.org)
  • Stable increase in revenues from our biomedical businesses, ability to generate net income as a parent company and progress in demonstrating the safety and efficacy of our stem cells for the treatment of Parkinson's disease and stroke position us as a leader in regenerative medicine field," stated Andrey Semechkin, Ph.D., CEO and Co-Chairman of ISCO. (marketwired.com)
  • cell lines
  • Federal funding of research using existing embryonic stem cell lines is consistent with the President's belief in the fundamental value and sanctity of human life. (archives.gov)
  • The embryos from which the existing stem cell lines were created have already been destroyed and no longer have the possibility of further development as human beings. (archives.gov)
  • Today's decision relates only to the use of federal funds for research on existing stem cell lines derived in accordance with the criteria set forth above. (archives.gov)
  • The Australian Academy of Science 's Professor John White argues that the decision is urgent, because existing stem cell lines are insufficient or unacceptable for research to continue. (abc.net.au)
  • development
  • This position has resulted in the 14‐day rule that permits research on human embryos to the point where the primitive streak appears, the point in development after which embryos cannot split into twins or fuse together anymore (Hyun et al , 2016 ). (cloudfront.net)
  • CRISPR/Cas9 and related genome editing techniques are already revolutionising scientific research, through use in the development of new cell and animal models. (phgfoundation.org)
  • Development expenses decreased by 8% to $3.65 million due primarily to reductions in cost of sales and consulting expenses relating to our research and development projects, partially offset by an increase in sales and marketing spending. (marketwired.com)
  • Net loss from development activities was $9.81 million, compared to $11.36 million in 2011 reflecting a reduction of $1.55 million or 14% primarily due to favorable reductions in cost of sales, research and development and general and administrative expenses. (marketwired.com)
  • We expect our net operating loss to continue declining quarter over quarter through 2015 year-end as our research and development expenses are expected to continue decreasing due to the completion of multiple preclinical studies during the three months ended June 30, 2015. (marketwired.com)
  • The first vessels in the developing embryo form through vasculogenesis, after which angiogenesis is responsible for most, if not all, blood vessel growth during development and in disease. (wikipedia.org)
  • therapy
  • The Committee recognizes that the science of this field, especially the science of stem cell research and therapy, is changing rapidly and anticipates that future changes will require revisiting past issues and either modifying previous guidelines or creating new ones in order to address formerly unimagined possibilities. (docplayer.net)
  • advances
  • As a non-profit entity, Michigan Medicine uses positive operating margins to fund continued advances in patient care, education, research, and the facilities needed to support these functions. (wikipedia.org)
  • long
  • The long term impact of this on medical research will be difficult to calculate, but it is likely that research in certain areas will become quicker and easier to carry out. (phgfoundation.org)
  • already
  • The University of Chicago re-assumed responsibility, until in December 1947 Union Carbide and Carbon Co., which already operated two other facilities at Oak Ridge, took control of the laboratory and Alvin Weinberg was named Director of Research ORNL, and in 1955 Director of the Laboratory. (wikipedia.org)
  • fundamental
  • The President's decision reflects his fundamental commitment to preserving the value and sanctity of human life and his desire to promote vital medical research. (archives.gov)
  • medical
  • Nonetheless, the results are "very promising," said neurogeneticist linkurl:Carolyn Sue;http://www.kolling.usyd.edu.au/research/neurogenetics-group/csue.php of the Kolling Institute of Medical Research at the University of Sydney in Australia, who was also not directly involved in the research. (the-scientist.com)
  • In 1950, Richard Doll published research in the British Medical Journal showing a close link between smoking and lung cancer. (wikipedia.org)