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TurnipTobaccoCauliflower MosaiPepino mosaic virusViralProteinCucumber mosaiReplicationProteinsTomatoWheat streaInfectionCowpeaResistancePepMVCaMVGenomeParticlesIsolatesSolanumDiseasesHeterologousVectorCropsSymptomsPromoterVectorsPathwaysVirionsPoorly understoodWeedsSphericalPlantsInfectiousInteractionsSpeciesInnateWidelyResultsPlant virusHerpesRegulationHostsExperimentsInvestigate
Turnip7
  • Recent investigations in our labs, by analyzing the whole-plant dynamics of a turnip crinkle virus (TCV) population, coupled with cell biological interrogation of individual TCV variants, revealed possible novel mechanisms for cross protection and the closely related process of superinfection exclusion (SIE). (frontiersin.org)
  • We cloned NSs from the Hawaii isolate of TSWV and using two independent assays show for the first time that this protein restored pathogenicity and supported the formation of local infection foci by suppressor-deficient Turnip mosaic virus and Turnip crinkle virus . (unl.edu)
  • The poly(A) binding protein is internalized in virus-induced vesicles or redistributed to the nucleolus during turnip mosaic virus infection. (harvard.edu)
  • Using the Chinese cabbage ( Brassica campestris ) cultivar 'Chun-goang' as a host and turnip mosaic virus (TuMV) as a pathogen, we studied the effects of ambient temperature (13°C, 18°C, 23°C, 28°C and 33°C) on disease intensity and the speed of systemic infection. (ppjonline.org)
  • Using this dynamic, semi-quantitative approach, the researchers observed that Turnip mosaic virus - their plant model virus of choice - spreads in their model plant Arabidopsis thaliana , arrives at the stem cells within the shoot tip , and even enters these cells, but is then quickly excluded. (oeaw.ac.at)
  • In the fight against Turnip mosaic virus, both salicylic acid and RDR1 are necessary to expel the virus from the stem cells - however, RDR1 is not produced within the stem cells themselves, but in the tissue below the stem cells and in the vasculature, Incarbone adds. (oeaw.ac.at)
  • Cucumber mosaic virus (CMV), Turnip mosaic virus (TuMV) and Turnip crinkle virus (TCV) are important plant infecting viruses. (elsevierpure.com)
Tobacco18
Cauliflower Mosai6
  • Cauliflower mosaic virus (CaMV) is a member of the genus Caulimovirus, one of the six genera in the family Caulimoviridae, which are pararetroviruses that infect plants. (wikipedia.org)
  • The cauliflower mosaic virus (CaMV) is a member of the family Caulimoviridae. (wikipedia.org)
  • Cauliflower Mosaic Virus (CaMV) is a pararetrovirus of crucifer plants. (i-sis.org.uk)
  • This is the CaMV 35S promoter sequence is derived from cauliflower mosaic virus. (gmo-safety.eu)
  • Association of the P6 protein of Cauliflower mosaic virus with plasmodesmata and plasmodesmal proteins. (unige.ch)
  • The P6 protein of Cauliflower mosaic virus (CaMV) is responsible for the formation of inclusion bodies (IBs), which are the sites for viral gene expression, replication, and virion assembly. (unige.ch)
Pepino mosaic virus2
  • In this study, we determined the role of invasive weed species as potential hosts for ToBRFV and pepino mosaic virus (PepMV). (preprints.org)
  • Pepino mosaic virus (PepMV) (genus Potexvirus , family Flexiviridae ), a widespread plant virus, is a promising candidate expression vector for plants because of its high level of accumulation in its hosts and the absence of severe infection symptoms. (biomedcentral.com)
Viral15
  • Cauliflower Mosaic Viral Promoter - A Recipe for Disaster? (i-sis.org.uk)
  • This paper examines the safety implication of recent revelations on the recombination hotspot of the cauliflower mosaic viral (CaMV) promoter, which is in practically all current transgenic crops released commercially or undergoing field trials. (i-sis.org.uk)
  • Possible roles of endogenous plant viral sequences. (cambridge.org)
  • I took up a position at Oxford Brookes University in 2012 investigating the role of reticulon proteins in ER tubulation and viral trafficking in order to develop my international reputation in ER research and advanced imaging. (brookes.ac.uk)
  • Our new mechanistic model postulates that, for RNA viruses like TCV, SIE manifests a viral function that denies progeny viruses the chance of re-replicating their genomes in the cells of their "parents," and it collaterally targets highly homologous superinfecting viruses that are indistinguishable from progeny viruses. (frontiersin.org)
  • Using mean-field theory, we explore the role of the secondary structure of RNA on the viral assembly by modeling the RNA as an annealed branched polymer. (escholarship.org)
  • The mechanism by which NSs suppresses RNA silencing and its role in viral infection and movement remain to be determined. (unl.edu)
  • RDR1 ramps up production of double-stranded RNA from viral RNA, giving plants more virus-specific sequences to direct the defense mechanism against the invading virus. (oeaw.ac.at)
  • Moreover, analysis of miRNAs during CMV and TuMV and CMV and TCV infections have demonstrated the role of miRNAs in the down regulation of host genes in response to viral infections. (elsevierpure.com)
  • These results identified the commonly expressed virus-responsive genes and pathways during plant-virus interaction which might develop novel antiviral strategies for improving plant resistance to mixed viral infections. (elsevierpure.com)
  • The core claim of these virus denialists is that the so called PCR test, which is designed to detect viral material, is highly unreliable, because it doesn't detect anything interesting, other than random cell material. (integralworld.net)
  • iii) Name two viral diseases and their causal viruses. (rbsesolutions.com)
  • To support the ongoing management of viral respiratory diseases while transitioning out of the acute phase of the COVID-19 pandemic, many countries are moving toward an integrated model of surveillance for SARS-CoV-2, influenza virus, and other respiratory pathogens. (cdc.gov)
  • Our results show that class XI myosins play specific roles in the reproduction and intracellular movement of TMV in association with the dynamic endoplasmic reticulum network, whereas class VIII myosins support the specific targeting of the viral movement protein to plasmodesmata and thus the cell-to-cell movement of the virus. (prelekara.sk)
  • Subcellular localization analysis using fluorescently tagged NtREM, ToMV, and viral replication and movement proteins (MPs) indicated that virus infection and transient expression of the viral proteins promoted the formation of NtREM aggregates by altering the subcellular distribution of NtREM, which was localized uniformly on the plasma membrane under normal conditions. (elsevierpure.com)
Protein8
  • The virus-protein-coat functionality can be used for the directed bioconjugation of metallic particles to make anisotropically conductive virus wires. (ncsu.edu)
  • To condition susceptibility, most plant viruses encode silencing suppressors that interfere with this process, such as the Tomato spotted wilt virus (TSWV) NSs protein. (unl.edu)
  • Our results show that RelA plays a critical role in activation of immune system genes in response to nonspecific stimuli and demonstrate a novel proapoptotic function for this protein in Fas-induced cell death. (rupress.org)
  • These regulatory sequences do not code for any protein but rather plays a central role in the regulation of gene activity in the soy plant by either switching the genes on or switching them off. (gmo-safety.eu)
  • Shukla, D.D. Expression of potyvirus coat protein in Escherichia coli and yeast and its assembly into virus-like particles. (eurekaselect.com)
  • The subject of my master's thesis explored the difference in translational efficiency of the p3a movement protein, from either genomic or subgenomic RNA3a, in Brome Mosaic Virus. (mcw.edu)
  • Plant viruses are useful expression vectors because they can mount systemic infections allowing large amounts of recombinant protein to be produced rapidly in differentiated plant tissues. (biomedcentral.com)
  • We explored several strategies for vector development including coat protein (CP) replacement, duplication of the CP subgenomic promoter (SGP) and the creation of a fusion protein using the foot-and-mouth disease virus (FMDV) 2A catalytic peptide. (biomedcentral.com)
Cucumber mosai7
  • Mirhosseini-Chahooki SZ, Massumi H, Heydarnejad J, Hosseinipour A, Abdoshahi R, Maddahian M (2022) The reaction of forty cucurbits genotypes against Cucumber mosaic virus . (ac.ir)
  • Cucumber mosaic virus (CMV) is one of the most common pathogens of cucurbits plants in the world. (ac.ir)
  • 1. Arzani A, Ahoonmanesh A (2000) Study of resistance to Cucumber mosaic virus, Watermelon mosaic virus and Zucchini yellow mosaic virus in melon cultivars. (ac.ir)
  • 4. Asma A, Zahoor A, Farzana B, Ubairah Neelam R (2015) Varietal reaction of Cucumber against Cucumber mosaic virus. (ac.ir)
  • 9. Farzadfar S, Pourrahim R, Arafati N (2013) Molecular identification of Cucumber mosaic virus subgroup IB isolate in south Iran. (ac.ir)
  • 12. Maddahian M, Massumi H, Heydarnejad J, Hosseini pour A (2013) Phylogenetic analysis of Iranian Cucumber mosaic virus isolates from Kerman and Yazd provinces. (ac.ir)
  • 14. Munshi AD, Panda P, Mandal B, Bisht IS, Rao ES, Kumar K (2008) Genetics of resistance to Cucumber mosaic virus in Cucumis sativus var. (ac.ir)
Replication5
  • The synthesis of 3 H-uridine-labelled complete virus, virus RNA and presumed replicative form (RF) were studied during the replication of southern bean mosaic virus (SBMV) in soybean callus cells. (microbiologyresearch.org)
  • Accumulation of an RNA with electrophoretic properties similar to the presumptive RF of SBMV-RNA, was found in inoculated cells incubated at 6 °C from 84 to 96 h, suggesting a possible blockage of virus replication at the double-stranded RNA stage in these cells. (microbiologyresearch.org)
  • The genome of the geminivirus tomato golden mosaic virus (TGMV) consists of two circular DNA molecules designated as components A and B. The A component contains the only virally-encoded function required for autonomous replication in infected plant cells. (ncsu.edu)
  • Although primarily based on observations made with TCV, this new model could be broadly applicable to other viruses as it provides a molecular basis for maintaining virus genome fidelity in the face of the error-prone nature of virus replication process. (frontiersin.org)
  • Our experiments have also highlighted virus requirements for replication in single cells as well as intercellular and long-distance movement. (biomedcentral.com)
Proteins2
  • We have generated a novel tool for the expression of recombinant proteins in plants and for the functional analysis of virus and plant genes. (biomedcentral.com)
  • Argonaute 5 family proteins play crucial roles in the defence against Cymbidium mosaic virus and Odontoglossum ringspot virus in Phalaenopsis aphrodite subsp. (nchu.edu.tw)
Tomato2
  • The new tobamovirus tomato brown rugose fruit virus (ToBRFV), recently identified in the Middle-East, overcomes the Tm-22 resistance allele in the cultivated tomato varieties grown in greenhouses. (preprints.org)
  • Transient expression of heterologous RNAs using tomato golden mosaic virus. (ncsu.edu)
Wheat strea1
  • Pyramiding of alien-derived Wheat streak mosaic virus (WSMV) resistance and resistance enhancing genes in wheat is a cost-effective and environmentally safe strategy for disease control. (nature.com)
Infection12
  • The CMD virus has two routes of infection: through vectors and also through infected crops. (deepdyve.com)
  • 2007. Cajal bodies and the nucleolus are required for a plant virus systemic infection . (hutton.ac.uk)
  • In this context, pVNPs are safer than VNPs derived from mammalian viruses because there is no risk of infection or reversion to pathogenicity. (eurekaselect.com)
  • The infection of Telosma mosaic virus (TeMV), a potyvirus, and its effects on the phytochemical components of P. edulis remain largely unknown in China. (biomedcentral.com)
  • P. edulis plants showing distorted leaves and severe mosaic skin on green fruit were identified with TeMV infection through traditional transmission electron microscopy, RT-PCR and modern small RNA sequencing (sRNA-seq) platform. (biomedcentral.com)
  • The contents of phytochemical components and the activities of antioxidative enzymes were compared between virus-infected and virus-free P. edulis to confirm the effects of TeMV infection on host plant. (biomedcentral.com)
  • The effect of viruses infection on the chemical composition of host plants has been widely reported. (biomedcentral.com)
  • When viruses successfully infect plants, the infection often spreads through the entire organism. (oeaw.ac.at)
  • Through a series of targeted experiments, the researchers were able to see that during virus infection, salicylic acid production is activated. (oeaw.ac.at)
  • This role has most recently been demonstrated by the COVID-19 pandemic, during which existing approaches to respiratory pathogen surveillance, such as community testing, were rapidly scaled up and many enhanced or new surveillance activities, such as infection prevalence surveys, were put into place ( 1 ). (cdc.gov)
  • Plant viruses have evolved to borrow this transport mechanism to aid their infection and spread within the plant. (prelekara.sk)
  • However, little is known about which of the many plant myosins are essential and at which specific steps they act to support virus infection. (prelekara.sk)
Cowpea1
  • Lomonossoff, G.P. Cowpea mosaic virus: the plant virus-based biotechnology workhorse. (eurekaselect.com)
Resistance3
  • through resistance to either the vector or the virus itself. (nature.com)
  • 2. Ashfaq M, Aslam khan M, Mughal SM, Javed N, Mukhtar T, Bashir M (2007) Evaluation of urdbean germplasm for resistance against Urdbean leaf crinkle virus. (ac.ir)
  • 3. Ashfaq M, Iqbal S, Mukhtar T, Shah H (2014) Screening for resistance to Cucumber mosaic cucumovirus in Chilli Pepper. (ac.ir)
PepMV3
  • In addition, when inoculated with ToBRFV or PepMV-IL disease symptom manifestations were observed in S. rostratum plants and the symptoms were exacerbated upon mixed infections with both viruses. (preprints.org)
  • The possible use of PepMV as a virus-induced gene silencing vector to study gene function was also demonstrated. (biomedcentral.com)
  • A stable PepMV vector was generated by expressing the transgene as a CP fusion using the sequence encoding the foot-and-mouth disease virus (FMDV) 2A catalytic peptide to separate them. (biomedcentral.com)
CaMV5
  • CaMV induces a variety of systemic symptoms such as mosaic, necrotic lesions on leaf surfaces, stunted growth, and deformation of the overall plant structure. (wikipedia.org)
  • Phylogenetically, CaMV belongs to a group of caulimoviruses most closely related to the hepadnaviruses of animals, which includes the human hepatitis B virus. (i-sis.org.uk)
  • This suggests that CaMV evolved subsequent to the horizontal transfer of a retrotransposon to the cruciferae, either as the result of capture of RTgene by a pre-existing virus or by the transposable element acquiring additional genes to become a virus. (i-sis.org.uk)
  • The roles of the different 35S promoter domains in pathogenesis of CaMV have only been studied fairly recently (4, 9). (i-sis.org.uk)
  • Because CaMV virions accumulate preferentially in P6 IBs, we hypothesized that P6 IBs have a role in delivering CaMV virions to the plasmodesmata. (unige.ch)
Genome2
  • In the second part, we explore the role of genome on the structure of human immunodeficiency virus (HIV) shells (Chapter 6). (escholarship.org)
  • In Chapter 7, we carry out coarse-grained simulations to examine the HIV maturation pathways and the role of genome and membrane on the formation of conical shells. (escholarship.org)
Particles5
  • The first part focuses on spherical single stranded (ss) RNA viruses or virus like particles. (escholarship.org)
  • Briggs, M. Virus-like particles in serum of patients with Australia-antigen-associated hepatitis. (eurekaselect.com)
  • Chackerian, B. Virus-like particles: flexible platforms for vaccine development. (eurekaselect.com)
  • Firstly, approximately 700 nm linear virus particles, representing TeMV, were detected in infected P. edulis fruits and leaves with Electron microscopy. (biomedcentral.com)
  • Scientists had mistaken very small cell particles called "exosomes" to be viruses. (integralworld.net)
Isolates2
  • Host plants pre-infected with a mild isolate of a virus frequently become protected against secondary infections (superinfections) by more severe isolates of the same virus, or closely related viruses, but remain susceptible to more distantly related viruses. (frontiersin.org)
  • While a unified mechanistic understanding of cross protection remains elusive, it is important to note that similar superinfection exclusion (SIE) effect can be induced by symptomatic - in place of mild - virus isolates as well, as long as the primary and superinfecting viruses are genetically closely related. (frontiersin.org)
Solanum1
Diseases6
  • Despite its widespread use in managing important plant virus diseases, the mechanism of cross protection remains poorly understood. (frontiersin.org)
  • Dumont, Yves 2020-08-06 00:00:00 [In this chapter, an application of Mathematical Epidemiology to crop vector-borne diseases is presented to investigate the interactions between crops, vectors, and virus. (deepdyve.com)
  • Infectious Diseases and Our Planet Application of Mathematical Epidemiology to Crop Vector-Borne Diseases: The Cassava Mosaic Virus Disease Case %22&body=%0AI%20found%20an%20article%20you%20might%20be%20interested%20in. (deepdyve.com)
  • 8. Duffus JE (1971) Role of weeds in the incidence of virus diseases. (ac.ir)
  • The role of apoptosis in neuromuscular diseases and prospects for anti-apoptosis therapy. (harvard.edu)
  • Surveillance plays a critical role in the management of epidemic diseases. (cdc.gov)
Heterologous1
  • Demonstrating the suppression of RNA silencing directed against heterologous viruses establishes the foundation to determine the means used by NSs to block this antiviral process. (unl.edu)
Vector1
  • Early vectors suffered from limitations such as instability and low yields, but this has been addressed by the genetic modification of vector sequences and by delivering virus vectors into plant cells using Agrobacterium tumefaciens [ 39 , 40 ]. (biomedcentral.com)
Crops3
  • 5. Bananej K, Vahdat A (2008) Identification, distribution and incidence of viruses in field-grown cucurbit crops of Iran. (ac.ir)
  • 10. Kumari S, Nagendran K, Dubey V, Das B, Pandey KK, Singh J (2021) Investigations on annual spreading of viruses infecting cucurbit crops in Uttar Pradesh State, India. (ac.ir)
  • The potato virus Y (PVY) is a plant virus that causes massive crop losses globally, especially in Solanaceae crops. (bvsalud.org)
Symptoms1
  • TeMV-infected P. edulis showed severe symptoms, such as mosaic and distorted leaves, mosaic skin on green fruit and decreased fruit size. (biomedcentral.com)
Promoter1
  • These studies show that the loss of up to 40 amino acids from the 3' end of gene Vl (which overlaps with the 35S promoter) had no effect on pathogenesis whereas further truncation into a putative zinc finger region was fatal to the virus. (i-sis.org.uk)
Vectors1
  • Plant viruses and their vectors are strongly influenced by weather and climate. (ppjonline.org)
Pathways1
  • Furthermore, our work confirms that viruses employ all the accessible pathways to maturation, explaining many aspects of the previous HIV pathway experiments. (escholarship.org)
Virions1
  • The synthesis of complete virus, measured by the incorporation of 3 H-uridine into virions and by infectivity assays, rose rapidly during 0 to 34 h after transfer to 25 °C. An RNA with a mol. (microbiologyresearch.org)
Poorly understood1
  • This small group of cells generates all plant tissues above ground, including the next plant generation, and for reasons still poorly understood, viruses are unable to proliferate in these cells. (oeaw.ac.at)
Weeds1
  • The highest in-direct impact may be attributed to the role of invasive weeds as virus reservoirs especially within the commercial growing areas. (preprints.org)
Spherical1
Plants6
  • Plants pre-infected with a mild variant of a virus frequently become protected against more severe variants of the same virus through the cross protection phenomenon first discovered in 1929. (frontiersin.org)
  • At the molecular level, the genomes of superinfecting viruses are all but undetectable in most of the cross-protected plants, suggesting a failure of cellular entry or multiplication by the superinfectors (e.g. (frontiersin.org)
  • Protective role of S-methylmethionine-salicylate in maize plants infected with Maize dwarf mosaic virus , EUROPEAN JOURNAL OF PLANT PATHOLOGY 149: (1) pp. 145-156. (doktori.hu)
  • The genetically engineered soy is similar in structure as well as function to the naturally occurring soy plants while the EPSPS gene in plants and bacteria are also similar regarding the roles they play. (gmo-safety.eu)
  • Viruses are a threat to all organisms, including plants. (oeaw.ac.at)
  • Everything under the sun from animals and plants to fungi, viruses and bacteria, even the most primitive archaea [1] has been sequenced these days and aligned within the larger Tree of Life. (integralworld.net)
Infectious3
  • Foreign gene sequences could be inserted into deletion mutants, which may alter the infectious characteristics of the virus. (i-sis.org.uk)
  • Richert-Pöggeler , KR , Noreen , F , Schwarzacher , T , Harper , G , Hohn , T ( 2003 ) Induction of infectious petunia vein clearing (pararetro) virus from endogenous provirus in petunia. (cambridge.org)
  • Isolation of infectious ribonucleic acid from southern bean mosaic virus. (microbiologyresearch.org)
Interactions1
  • San A, Palmieri D, Saxena A, Singh S. In silico study predicts a key role of RNA-binding domains 3 and 4 in nucleolin-miRNA interactions. (cuny.edu)
Species1
  • The distribution and abundance of both Solanaceae species increase the risks of virus transmission between species. (preprints.org)
Innate1
  • Furthermore, we described the versatility of plant viruses, with innate immunostimulatory properties, in providing a huge natural resource of carriers that can be used to develop the next generation of sustainable vaccines. (eurekaselect.com)
Widely1
Results1
  • The results suggest that H2 plays an important role in regulating the level of H2-oxidizing activity in this soluble hydrogenase. (ncsu.edu)
Plant virus2
  • In the rapidly evolving field of nanotechnology, plant virus nanoparticles (pVNPs) are emerging as powerful tools in diverse applications ranging from biomedicine to materials science. (eurekaselect.com)
  • 5. AmariK, LerichA, Schmitt-KeichingerC, DoljaVV, RitzenthalerC (2011) Tubule-guided cell-to-cell movement of a plant virus requires class XI myosin motors. (prelekara.sk)
Herpes1
Regulation1
  • Role of hydrogen in the activation and regulation of hydrogen oxidation by the soluble hydrogenase from Alcaligenes eutrophus H16. (ncsu.edu)
Hosts1
  • Plant viruses threaten the health of their hosts, can spread swiftly and globally, and challenge agricultural productivity. (oeaw.ac.at)
Experiments1
  • Pulse-chase experiments, within limits, suggested the possible precursor role of the postulated RF in the synthesis of virus RNA. (microbiologyresearch.org)
Investigate1
  • In follow-up work, Incarbone will now investigate how viruses are stopped from passing into an infected plant's seeds and offspring- which develop from the protected stem cells. (oeaw.ac.at)