• apical
  • We have previously shown that a carbohydrate-dependent association between galectin-3 and highly O-glycosylated mucins contributes to form an apical barrier at the ocular surface epithelia. (arvojournals.org)
  • lung
  • The experiments proposed within this application will contribute to our overall understanding of how the epithelium of the maturing postnatal lung can direct the development of a pathologic immune response to inhaled allergens. (grantome.com)
  • Parotid epithelium was able to develop in lung mesenchyme, but not so well as in its own mesenchyme. (biologists.org)
  • Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. (elsevier.com)
  • survival
  • Retrograde signaling from the brain to the olfactory sensory epithelium is important for neuronal survival, but the importance of the olfactory bulb in retrograde signaling during the naturally-induced, neuronal plasticity occurring during metamorphosis is unclear. (uwindsor.ca)
  • stimuli
  • This model shows that stromal cells, but not an androgenic stimuli, are required for architectural organisation of prostate epithelium. (biologists.org)
  • We studied first, whether nitric oxide could relax isolated tracheal strips, and then examined the effects of known inhibitors of endothelium-dependent relaxation (EDR) in the vascular system, hemoglobin methylene blue, and N^G-monomethyl-L-arginine (L-NMMA), on epithelium-dependent relaxation (EpDR) induced by hyperosmotic stimuli in perfused whole tracheal preparations, Nitric oxide produced concentration-dependent and complete relaxation of epithelium-denuded tracheal strips. (nii.ac.jp)
  • barrier
  • Important for the barrier function of intenstinal epithelium, its cells are joined securely together by four types of junctions (cell junctions), which can be identified at the ultrastructural level: Gap junctions Desmosomes Adherens junctions Tight junctions Gap junctions bring the adjacent cells within 2 nanometers of each other. (wikipedia.org)
  • cultures
  • Na+ and Cl- currents were studied in primary cultures of human nasal epithelium derived from non-cystic fibrosis (non-CF) and cystic fibrosis (CF) patients. (semanticscholar.org)
  • regulatory
  • SLiM functions in almost every pathway due to their critical role in regulatory function, protein-protein interaction and signal transduction. (wikipedia.org)
  • Including development, BDNF has important regulatory roles in the development of the visual cortex, enhancing neurogenesis, and improving learning and memory. (wikipedia.org)
  • gene
  • The bestrophin 2 gene is mainly expressed in the non-pigmented ciliary epithelium and colon. (wikipedia.org)
  • Of particular relevance is the presence of the gene HCK which seems to play an important role anti-inflammation. (wikipedia.org)
  • cells
  • In this study we set out to determine if sAC is expressed in RPE cells and whether it plays a role in generating the LP. (arvojournals.org)
  • Autophagy might have protective roles against high glucose induced injury in ARPE19 cells via regulating PINK1/Parkin pathway and BNIP3L. (conicyt.cl)
  • Lactiferous ducts are lined by a columnar epithelium supported by myoepithelial cells. (wikipedia.org)
  • The cells of the columnar epithelium form tight junctions which are regulated by hormones and local factors like pressure and casein content. (wikipedia.org)
  • The epithelium is composed of a single layer of cells. (wikipedia.org)
  • Helobdella triserialis), the provisional epithelium covering the cells plays a role in inducing the O fate. (wikipedia.org)
  • results
  • From these results we concluded that relaxation seen in this system is not due to tissue hypoxia but due to the release of relaxing factor from tracheal epithelium. (nii.ac.jp)
  • The results are interpreted in terms of morphogenetic and growth control of salivary epithelium by mesenchyme, the subsequent cytodifferentiation of the terminal buds being typical of the organ from which the epithelium was derived. (biologists.org)
  • examine
  • The olfactory system of the African clawed frog ( Xenopus laevis ) undergoes dramatic rearrangements during metamorphosis, making this an ideal system in which to examine interactions between the brain and the olfactory sensory epithelium. (uwindsor.ca)
  • plays a role
  • The cadherin subunit, β-catenin plays a role in cell-cell adhesion by controlling cadherin-mediated cell adhesion at the plasma membrane. (wikipedia.org)
  • single
  • Amylase activity was greater when the epithelium from a single parotid rudiment was recombined with submandibular mesenchyme than with its own mesenchyme. (biologists.org)
  • function
  • When compared to normal tissue, all GC epithelia had lower levels of FOXO4 located in the nucleus, consistent with less FOXO4 effector activity and FOXO4's function as a suppressor of carcinogenic properties. (wikipedia.org)
  • further
  • Our data demonstrate that sAC is expressed by the RPE and that it contributes to the generation of the LP. Further study will be necessary to determine how cAMP generated by sAC may be involved in the LP response as a role for cAMP in generating the LP has not previously been observed. (arvojournals.org)
  • Further evidence of the role of gut flora in the cause of inflammatory bowel disease is that IBD-affected individuals are more likely to have been prescribed antibiotics in the 2-5 year period before their diagnosis than unaffected individuals. (wikipedia.org)