Risk atherosclerosis. Medical search. Frequent questions

Conclusions Ultrasound assessment of subclinical atherosclerosis may improve risk stratification of patients with psoriatic disease, particularly of those with PsA. (bmj.com)
Is periodontitis a risk factor for ischaemic stroke, coronary artery disease and subclinical atherosclerosis? (cam.ac.uk)
We therefore used Mendelian randomization to test whether periodontitis is causally associated with stroke, coronary artery disease, or subclinical atherosclerosis. (cam.ac.uk)
We used existing data on carotid intima-media thickness in UK Biobank as a marker of subclinical atherosclerosis (N = 22,179). (cam.ac.uk)
Similarly, we found no association for periodontitis and subclinical atherosclerosis (β -0.002, 95% CI -0.004 to 0.001). (cam.ac.uk)
To identify dietary patterns associated with subclinical atherosclerosis measured as coronary artery calcification (CAC). (nih.gov)
Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease. (ox.ac.uk)
Reduces the development of subclinical atherosclerosis and slows progression as time since cessation lengthens. (cdc.gov)
To assess the association of HIV infection, HIV disease parameters (including CD4+ T-cell counts, HIV viral load, and AIDS) and antiretroviral medication use with subclinical carotid artery atherosclerosis. (elsevierpure.com)
Beyond traditional cardiovascular disease risk factors, low CD4+ T-cell count is the most robust risk factor for increased subclinical carotid atherosclerosis in HIV-infected women and men. (elsevierpure.com)
Subclinical Vascular Disease Burden and Premature Mortality Among Middle-aged Adults: the Atherosclerosis Risk in Communities Study. (bvsalud.org)

Long-term studies in adults have determined that the progression of atherosclerosis is related to the presence of specific risk factors that reinforce each other over time if not treated. (aafp.org)
They reported that abnormal inflammatory signaling was also related to DNMT3A and TET2 deficiency in blood cells that play a major role in inflammation response that promotes the progression of atherosclerosis. (news-line.com)
The etiology of atherosclerosis is unknown, but there are multiple factors that contribute to atherosclerotic plaque progression. (medscape.com)
The model] suggests that there is an association between long-term exposure to ozone and progression of atherosclerosis," he goes on to report. (medicalnewstoday.com)
Specifically, the study found an association between chronic ozone exposure and an "increased rate of carotid wall thickness progression and risk of new plaque formation. (medicalnewstoday.com)
A complete risk factor analysis including lipids and a glucose tolerance test was done initially, at 18 months and five years into the study along with repeat angiography to examine whose arteries showed progression of disease and whose who did not. (roadbikerider.com)
A statistical analysis of all their risk factors and blood chemistries was done to correlate what contributed to coronary artery disease progression. (roadbikerider.com)
Heart attacks are caused by progression of atherosclerosis with a coronary thrombosis being the precipitating factor in most (but not all). (roadbikerider.com)
Clearly Simvastatin did not affect the progression of the disease in those who already had documented atherosclerosis. (roadbikerider.com)
Over the past two decades, its role in the initiation, progression, and clinical sequelae of atherosclerosis has been both increasingly studied and recognised (1). (escardio.org)
We have shown that relatively low doses of THC initiated after manifestation of clinically detectable artery lesions significantly inhibit atherosclerosis progression in mice," write Dr Sabine Steffens (University Hospital, Geneva, Switzerland) and colleagues in the April 6, 2005 issue of Nature . (medscape.com)
Furthermore, the inhibitory effects of THC on atherosclerosis progression are abolished in the presence of a CB2-receptor antagonist. (medscape.com)
The researchers hypothesized that THC could alter inflammatory processes crucial in atherosclerosis, thus limiting disease progression. (medscape.com)
Cite this: Oral cannabinoid therapy reduces progression of atherosclerosis - Medscape - Apr 07, 2005. (medscape.com)
For example, serum biomarkers, such as high sensitivity C-reactive protein (hsCRP) and cytokine levels, predict progression of atherosclerosis and risk of stroke. (medscape.com)
Progression of atherosclerosis to such life-threatening complications as a heart attack or stroke requires emergency treatment. (msdmanuals.com)
Along with hypertension, diabetes, and smoking, hyperlipidemia has consistently been shown to be one of the most significant and modifiable risk factors for coronary artery disease development and progression. (medscape.com)

Arteriosclerosis and atherosclerosis are sometimes used to mean the same thing, but there's a difference between the two terms. (mayoclinic.org)
Atherosclerosis is a specific type of arteriosclerosis. (mayoclinic.org)
Atherosclerosis , which develops from plaque buildup, is a common type of arteriosclerosis. (medlineplus.gov)
Atherosclerosis, or arteriosclerosis, happens when plaque collects and causes the arteries to narrow and harden, affecting blood flow. (medicalnewstoday.com)

Early diagnosis and treatment can stop atherosclerosis from worsening and prevent a heart attack, stroke or another medical emergency. (mayoclinic.org)
Sometimes the first symptom of atherosclerosis is a heart attack or stroke or even sudden coronary death," says Steven Borzak, MD, a cardiologist affiliated with JFK Medical Center in Atlantis, Florida. (sharecare.com)
Because of that, many people are unaware they have atherosclerosis until a medical emergency such as a heart attack or stroke occurs. (nghs.com)
When atherosclerosis impacts the carotid arteries, which supply blood to the brain, a person may experience symptoms common with stroke, including sudden weakness, paralysis or numbness, trouble speaking or seeing, dizziness or a sudden and severe headache. (nghs.com)
Atherosclerosis can lead to more dangerous cardiovascular events, such as coronary heart disease or peripheral artery disease , as well as a heart attack or stroke . (medicalnewstoday.com)
Daniel Bos and Arfan Ikram (both from the Erasmus Medical Center Rotterdam, the Netherlands), was that intracranial atherosclerosis is a major risk factor for stroke in the Western (white) population. (medicalresearch.com)
Traditionally, intracranial atherosclerosis has not been considered of major importance to stroke risk in Western populations. (medicalresearch.com)
In contrast, most research on intracranial atherosclerosis originates from Asian and African populations, where is was actually recognized as the most important risk factor of stroke. (medicalresearch.com)
Our study demonstrates that also in the Western population intracranial atherosclerosis is a major risk factor for stroke and should get more focus in clinical practice. (medicalresearch.com)
Our hypothesis was that atherosclerosis that is located in the vasculature directly supplying the brain would have more influence on the development of stroke compared to locations further away from the brain (such as heart or aorta). (medicalresearch.com)
This was in conjunction with the second hypothesis that intracranial atherosclerosis would be a major risk factor of stroke in Western populations too. (medicalresearch.com)
In that sense, our finding that intracranial atherosclerosis was indeed a strong risk factor for stroke, was not entirely unexpected. (medicalresearch.com)
Especially, the finding that the association between intracranial atherosclerosis and stroke firmly remained after adjustment for the presence of atherosclerosis in the carotid bifurcation, aortic arch and the coronary arteries, emphasizes the importance of intracranial atherosclerosis. (medicalresearch.com)
Over the past decades, there has not been much attention for intracranial atherosclerosis as cause of stroke in the Western (white) population. (medicalresearch.com)
In other words, intracranial atherosclerosis is an underestimated risk factor for stroke and deserves significantly more attention in current practice. (medicalresearch.com)
Compared to the extensive research that has been performed in this field, it is evident that much research is still to be done to assess the value of intracranial atherosclerosis as a potential predictor of stroke. (medicalresearch.com)
In recent years, there have been some clinical trials specifically targeting intracranial atherosclerosis in stroke patients , but have not been entirely conclusive. (medicalresearch.com)
People with hepatitis C are at higher risk of dying from cardiovascular disease, having a stroke, or developing other cardiovascular problems than people with similar risk factors for heart disease who do not have hepatitis C, a meta-analysis of published studies has shown. (hivandhepatitis.com)
Salvatore Petta and colleagues at the University of Palermo set out to pool data from published studies in order to produce more robust estimates of the risks of heart attack and stroke among people living with hepatitis C. (hivandhepatitis.com)
Research also shows that exposure to secondhand smoke increases risk of CHD and stroke. (cdc.gov)
Reduces the risk of disease and death from stroke, with risk approaching that of never smokers after cessation. (cdc.gov)
After adjustment for potential confounders, each unit increase in the TyG index was associated with a 32.1% higher risk of incident stroke. (biomedcentral.com)
The Global Burden of Disease Study found that 87.0% of the global burden of stroke was attributable to modifiable risk factors [ 1 ], suggesting the importance of early risk factor identification and control. (biomedcentral.com)
Insulin resistance (IR) is a hallmark of metabolic syndrome and is well-established as a critical risk factor for the occurrence and development of stroke [ 3 ]. (biomedcentral.com)
Therefore, the present study explored the influence of the baseline TyG index and different trajectories of its change over six visits on the risk of stroke and its subtypes using data from the Atherosclerosis Risk in Communities (ARIC) study in four US communities. (biomedcentral.com)
Statins inhibit HMG-CoA reductase and reduce cholesterol levels risk of coronary heart disease and stroke. (frontiersin.org)
Stroke is a leading cause of functional impairment and death worldwide, and atherosclerotic stenosis of a major cranial artery is one of the most common causes of in situ ischemic stroke, with a substantial risk of recurrent stroke episodes. (e-cmh.org)
A population-based cohort study in an hepatitis B virus (HBV)-endemic area reported that chronic liver disorder, rather than seropositivity for HBV, was linked to a decreased risk of ischemic stroke [ 7 ]. (e-cmh.org)
These effects lower the exercise threshold for angina and are an independent risk factor for heart attack and stroke ," he writes. (medscape.com)
Atherosclerosis is a major cause of mortality and morbidity, which is mainly driven by complications such as myocardial infarction and stroke. (nature.com)
Evidence continues to accumulate to suggest important roles for inflammation and genetic factors in the process of atherosclerosis and specifically in stroke. (medscape.com)
Inherited risk for stroke is likely multigenic, although specific single-gene disorders with stroke as a component of the phenotype demonstrate the potency of genetics in determining stroke risk. (medscape.com)
Blood vessel blockage due to atherosclerosis is a common cause of heart attack and stroke. (msdmanuals.com)
Atherosclerosis in the coronary arteries is the most common cause of myocardial infarction and atherosclerosis in the carotids and other major arteries supplying the brain is the major cause of stroke. (lu.se)
3. Development of mental health conditions (anxiety and depression) that independently increases the risk for a range of chronic health conditions, including CVD (obesity, stroke, atherosclerosis, arrhythmias, myocardial infarction, etc. (cdc.gov)

Diabetes is also associated with chronic inflammation, which can contribute to the development of atherosclerosis. (sharecare.com)
Chronic unresolved vascular inflammation is a critical factor in the development of atherosclerosis. (frontiersin.org)
The development of atherosclerosis is complicated, but the primary event seems to be repeated, subtle injury to the artery's inner lining (endothelium), through various mechanisms. (msdmanuals.com)

Other factors, such as chronic systemic inflammation that has been tightly linked to accelerated atherosclerosis partially explain the increased CV risk. (bmj.com)
Scientists from the Salk Institute and UC San Diego published new findings in Immunity on August 2, 2022, where they examined human blood cells and discovered a surprising link between mitochondria, inflammation and DNMT3A and TET2-two genes that normally help regulate blood cell growth but, when mutated, are associated with an increased risk of atherosclerosis. (news-line.com)
But how the DNMT3A and TET2 genes were involved in inflammation, and possibly atherosclerosis, was unknown. (news-line.com)
Missing or reducing this binding activity leads to mitochondrial DNA release and an overactive mitochondrial inflammation response, and we believe this may exacerbate plaque buildup in atherosclerosis. (news-line.com)
It's very exciting to see our discovery on TFAM depletion causing mitochondrial DNA stress and inflammation now has direct relevance for a disease like atherosclerosis," says Shadel, who holds the Audrey Geisel Chair in Biomedical Science. (news-line.com)
Atherosclerosis is a disease of large and medium-sized muscular arteries and is characterized by endothelial dysfunction, vascular inflammation, and the buildup of lipids, cholesterol, calcium, and cellular debris within the intima of the vessel wall. (medscape.com)
Processes involved in atherosclerosis include coagulation, inflammation, lipid metabolism, intimal injury, and smooth muscle cell proliferation (see the image below). (medscape.com)
It contributes to other risk factors, like high cholesterol, high blood pressure, and diabetes, and causes chronic inflammation that injures blood vessels and contributes to plaque formation. (sharecare.com)
Moderate drinking of this sort can increase levels of healthy HDL, lower your risk of blood clots, and decrease inflammation. (sharecare.com)
LDL cholesterol may oxidise in artery walls, causing inflammation and atherosclerosis. (wellnessofhealth.com)
Smoking: Smoking damages the endothelium , causing inflammation and atherosclerosis. (wellnessofhealth.com)
To achieve their findings, the researchers looked at parameters of atherosclerosis among middle-aged individuals along with sleep trends, conventional atherosclerosis risk factors, psychosocial risk factors, dietary habits, and inflammation. (belmarrahealth.com)
The authors suggest that the metabolic abnormalities common in people with hepatitis C may provide one explanation for the increased risk, but they also point to recent evidence showing that hepatitis C promotes inflammation, which contributes to the development of cardiovascular disease. (hivandhepatitis.com)
Despite abundant knowledge about the relationship between inflammation and coronary atherosclerosis, it is still unknown whether systemic inflammation measured as high-sensitivity C-reactive protein (hsCRP) is associated with coronary atherosclerosis in a general population. (lu.se)
Atherosclerosis is a disease characterized by chronic inflammation and fibrosis of the intima of large and medium sized arteries. (lu.se)

By using data of large population studies the concept of "Global Cardiovascular Risk" (GCVR) was defined and it was rapidly applied in clinical practice with the elaboration of risk charts, through the development of algorithms for primary prevention of CVD based on the simultaneous analysis of a few main risk factors (age, gender, diabetes, smoking, systolic blood pressure values and total cholesterol). (escardio.org)
The results of some epidemiologic studies conducted by using questionnaires suggest that dietary fat composition influences diabetes risk. (nih.gov)
The prevention and treatment of atherosclerosis require risk factor control, including the medical management of hypertension, hyperlipidemia and dyslipidemia, diabetes mellitus, and cigarette habituation. (medscape.com)
The epidemiological studies revealed the age, diabetes, smoking and atherosclerosis are related with LA. Our findings showed that CIMT as an atherosclerosis marker was higher in LA patients than control group. (magiran.com)
Diabetes: Poorly managed diabetes increases risk. (wellnessofhealth.com)
The risk was significantly higher in studies where the background rate of diabetes was above 10%, the prevalence of high blood pressure was above 20%, or the average age of the study population was above 50 years. (hivandhepatitis.com)
The authors note that even after allowing for the well-established risk factors for heart disease -- diabetes, high blood pressure, and smoking -- the risk of death, cardiovascular disease, and carotid artery disease was still elevated in people with hepatitis C. Indeed, they describe the effect of hepatitis C on cardiovascular risk as 'especially pronounced' in populations where diabetes, high blood pressure, or smoking are common. (hivandhepatitis.com)
Furthermore, elevated CRP levels are associated with an increased risk of type 2 diabetes in adults 16 and are correlated with insulin resistance in children. (nature.com)
Atherosclerosis (AS) is one of the most common complications of diabetes. (wjgnet.com)
The African Region is facing two problems related to diet and malnutrition: (i) undernutrition which is still the main cause of infant and childhood morbidity and mortality, and (ii) obesity, which is becoming a leading risk factor for CVD and diabetes, especially in urban areas. (who.int)
Hypertension and diabetes during pregnancy are associated with in- Results creased heart disease risk. (cdc.gov)
Pregnant women with chronic diabetes or hypertension engaging those who experience such conditions in recommended are at increased risk of infant and maternal morbidity (1-3). (cdc.gov)

In correlating the extent of vascular lesions with antemortem risk factors, study results showed a positive and significant association with body mass index, systolic blood pressure (except for fibrous plaques in the aorta), diastolic blood pressure (except for fibrous plaques in the coronary arteries), total cholesterol, LDL cholesterol and serum triglyceride levels. (aafp.org)
Smoking is the single most damaging and most preventable cause of atherosclerosis and vascular events. (sharecare.com)
The researchers performed carotid and femoral 3D vascular ultrasounds and computed tomography angiograms (CTAs) to identify atherosclerosis. (belmarrahealth.com)
Endothelial dysfunction is an early marker of atherosclerosis and levels of vascular relaxation are an indicator of endothelial health. (escardio.org)
Concomitantly, disturbances in vascular biology provide a pathophysiological basis for identifying individuals at increased risk of future acute cardiovascular events. (escardio.org)
The role of cardiovascular risk factors, common in atherosclerosis and dementia, is important for cognitive impairment and vascular dementia, while, on the Alzcheimer's pathology is disputable even today. (japt.gr)
Atherosclerosis represents an important chronic inflammatory process associated with several pathophysiological reactions in the vascular wall. (hindawi.com)
We adjusted for demographics and vascular and Alzheimer disease risk factors.ResultsOf 9,033 ARIC participants with sufficient Medicare coverage data (4,980 [55.1%] female, 1993 [22.1%] Black), 671 met the definition of LOE. (johnshopkins.edu)

If you have ED, talk with your provider about your risk of plaque buildup. (medlineplus.gov)

Independent markers of multifocal atherosclerosis -directly associated with an increased risk of CV events- are intima-media thickness, reduced ankle-brachial pressure index and impaired flow-mediated dilatation. (escardio.org)
To identify potential common pathways across the two diseases, we tested all recently published single nucleotide polymorphisms (SNPs) associated with human lung function (spirometry) for association with carotid intima-media thickness (cIMT) in 3,378 subjects with multiple CAD risk factors, and for association with CAD in a case-control study of 5,775 CAD cases and 7,265 controls. (ox.ac.uk)
Intima media thickness (IMT) is appropriate for atherosclerosis process diagnosis. (magiran.com)

Autopsy data from adults have also demonstrated a relationship between coronary artery disease and cardiovascular risk factors, including cigarette smoking and high cholesterol levels. (aafp.org)
The authors conclude that the extent of coronary and aortic lesions in children and young adults significantly correlates with the presence of cardiovascular risk factors, including body mass index, systolic blood pressure, serum LDL cholesterol level, triglyceride concentration and cigarette smoking. (aafp.org)
The FRS incorporates age, gender, smoking, hypertension, total cholesterol and high density lipoprotein (HDL) cholesterol, to derive an estimated risk of developing a CV event (MI, coronary death and angina) within 10 years. (bmj.com)
Atherosclerosis is the buildup of fats, cholesterol and other substances in and on the artery walls. (mayoclinic.org)
In atherosclerosis, plaque build-up in the arteries is made up of fat, cholesterol, calcium, and other substances from the blood. (singhealth.com.sg)
High cholesterol and atherosclerosis often go hand-in-hand. (sharecare.com)
High levels of saturated fat in the diet lead to higher levels of LDL (aka "bad" cholesterol), which can increase the risk of atherosclerosis. (sharecare.com)
Healthy levels of HDL (aka "good" cholesterol) can actually decrease your risk. (sharecare.com)
You can change some risk factors for atherosclerosis such as smoking, high cholesterol levels, high blood sugar (glucose) levels, lack of exercise, poor dietary habits, and high blood pressure. (hopkinsmedicine.org)
Atherosclerosis, also called hardening of the arteries, occurs when substances such as fat and cholesterol build-up along the walls of the arteries. (nghs.com)
Atherosclerosis is the result of fatty deposits - such as cholesterol , fat, or cellular waste - accumulating inside a person's arteries. (medicalnewstoday.com)
While researchers do not yet know what triggers atherosclerosis, factors such as high blood pressure , high cholesterol, and cigarette smoking are believed to cause much of the damage. (medicalnewstoday.com)
risk increases with high LDL cholesterol, triglycerides, and low HDL cholesterol. (wellnessofhealth.com)
LC has been traditionally believed to have a protective effect against cerebral atherosclerosis, based on factors such as arterial hypotension and reduced cholesterol synthesis and bleeding tendency [ 5 , 6 ]. (e-cmh.org)
High levels of lipoprotein(a), a type of "bad" cholesterol, may be associated with an 18-20% higher risk of cardiovascular disease among people who have hypertension, however, CVD risk was not higher among those without hypertension, according to new research published today in Hypertension, an American Heart Association journal. (news-medical.net)
A gene recognized as the strongest risk factor for Alzheimer's disease (AD) alters the way cholesterol moves around the brain and as we age, this altered movement likely contributes to loss of learning and memory, a team of researchers from the Icahn School of Medicine at Mount Sinai and the Massachusetts Institute of Technology reports. (news-medical.net)
According to the current paradigm, atherosclerosis is not a bland cholesterol storage disease, as previously thought, but a dynamic, chronic, inflammatory condition due to a response to endothelial injury. (medscape.com)
High triglycerides are associated with increased risk for coronary artery disease (CAD) inpatients with other risk factors, such as low high-density lipoproteins (HDL)-cholesterol, some patient groups with elevated apolipoprotein B, and patients with forms of low-density lipoproteins (LDL) that maybe particularly atherogenic. (cdc.gov)
LDL carries most of the circulating cholesterol and, when elevated, contributes to the development of coronary atherosclerosis. (cdc.gov)
LDL- cholesterol is measured to assess risk for CHD and to follow the progress of patients being treated to lower LDL-cholesterol concentrations. (cdc.gov)
Changes in physiological processes that increase the risk for CVD-high cholesterol, high blood pressure, high blood sugar, weakened immune response, high cortisol, and changes in appetite and digestive patterns. (cdc.gov)

Heavy drinking, on the other hand-more than 14 drinks per week for men and more than 9 drinks per week for women-can contribute to atherosclerosis and increase your risk for serious health problems and even death. (sharecare.com)
Each risk factor is believed to contribute to atherosclerosis in the same way-by causing damage along the inner lining of the arteries. (nghs.com)

Further advancements in the treatment of atherosclerosis requires a better understanding of the molecular disease mechanisms and development of interventions more specifically targeted towards these mechanisms. (lu.se)

Patients were stratified into three ultrasound-based risk categories (low, intermediate and high) according to the severity of atherosclerosis. (bmj.com)
Therefore, we investigated the possible association of ACE gene insertion/deletion (I/D) polymorphism and the severity of atherosclerosis, estimated on the basis of the number of coronary stenoses and critical arterial occlusions observed during coronary angiography. (degruyter.com)
The D allele of angiotensin I-converting enzyme gene insertion/deletion polymorphism is associated with the severity of atherosclerosis" Clinical Chemistry and Laboratory Medicine , vol. 46, no. 4, 2008, pp. 446-452. (degruyter.com)
Niemiec, P., Zak, I. and Wita, K. (2008) The D allele of angiotensin I-converting enzyme gene insertion/deletion polymorphism is associated with the severity of atherosclerosis. (degruyter.com)

We found that the genes DNMT3A and TET2, in addition to their normal job of altering chemical tags to regulate DNA, directly activate expression of a gene involved in mitochondrial inflammatory pathways, which hints at a new molecular target for atherosclerosis therapeutics," says Gerald Shadel, co-senior author, Salk professor and director of the San Diego Nathan Shock Center of Excellence in the Basic Biology of Aging. (news-line.com)

Mild atherosclerosis usually doesn't have any symptoms. (mayoclinic.org)
Atherosclerosis symptoms usually don't happen until an artery is so narrowed or clogged that it can't supply enough blood to organs and tissues. (mayoclinic.org)
Symptoms of moderate to severe atherosclerosis depend on which arteries are affected. (mayoclinic.org)
If you have atherosclerosis in the arteries in your arms and legs, you may have symptoms of peripheral artery disease, such as leg pain when walking (claudication) or decreased blood pressure in an affected limb. (mayoclinic.org)
The signs and symptoms of noncoronary atherosclerosis are highly variable. (medscape.com)
Patients with mild atherosclerosis may present with clinically important symptoms and signs of disease. (medscape.com)
Since atherosclerosis often doesn't have symptoms, how do you know if you have it? (sharecare.com)
What are the symptoms of atherosclerosis? (hopkinsmedicine.org)
Signs and symptoms of atherosclerosis may develop gradually, and may be few, as the plaque gradually builds up in the artery. (hopkinsmedicine.org)
The symptoms of atherosclerosis may look like other heart conditions. (hopkinsmedicine.org)
Atherosclerosis is what's considered a silent condition, meaning it doesn't typically cause any symptoms until an artery is severely narrowed or even blocked. (nghs.com)
In the early stages, atherosclerosis often does not cause any symptoms. (medlineplus.gov)
Medical history and physical examination: The doctor will inquire about your symptoms, family history of cardiovascular disease, and risk factors. (wellnessofhealth.com)
Symptoms, risk factors, and atherosclerosis location will determine diagnostic testing. (wellnessofhealth.com)

Noncoronary atherosclerosis refers to atherosclerotic disease affecting large and medium-sized noncoronary arteries (eg, extracranial cerebrovascular disease, lower extremity occlusive disease, aneurysmal disease). (medscape.com)
The term atherosclerosis is derived from the Greek "athero," meaning gruel, or wax, corresponding to the necrotic core area at the base of the atherosclerotic plaque, and "sclerosis" for hardening, or induration, referring to the fibrous cap of the plaque's luminal edge. (medscape.com)
Our results showed that a dietary pattern consisting of traditional Brazilian foods could be important to reducing the risk of atherosclerotic calcification and prevent future cardiovascular events, whereas a convenience dietary pattern was positively associated with this outcome. (nih.gov)
For these, reasons both leukotriene synthesis inhibitors and leukotriene receptor antagonists have been suggested for inducing beneficial effects at different stages of the atherosclerosis process and may represent a new therapeutic target in the treatment of atherosclerotic vessel diseases, in particular in acute coronary syndrome. (hindawi.com)
We aimed to investigate the silent atherosclerotic burden of cervicocephalic vessels in cirrhotic patients compared with the general population, as well as the relevant risk factors including coronary parameters. (e-cmh.org)
These complications are caused by thrombotic arterial occlusion localized at the site of high-risk atherosclerotic plaques, of which early detection and therapeutic stabilization are urgently needed. (nature.com)
We suggest that near-infrared autofluorescence imaging is a novel technology that allows identification of atherosclerotic plaques with intraplaque hemorrhage and ultimately holds promise for detection of high-risk plaques in patients. (nature.com)
The development of a method to reliably identify high-risk atherosclerotic plaques is seen as one of the major quests of contemporary cardiovascular medicine. (nature.com)
Significant efforts have been made to characterize and risk stratify carotid and coronary atherosclerotic plaques using various imaging technologies. (nature.com)
We here propose the use of near-infrared autofluorescence (NIRAF) for the identification of high-risk atherosclerotic plaques. (nature.com)
In contrast, our study demonstrates that autofluorescence in the NIR range uniquely characterizes atherosclerotic plaques with intraplaque hemorrhage and may allow classification of atherosclerotic plaques into lesions of low or high risk for future cardiovascular events. (nature.com)
This mouse model was instrumental for the description of NIRAF as a potential indicator of an atherosclerotic plaque's risk in causing future cardiovascular events. (nature.com)
Besides establishing fluorescence emission tomography (FLECT) as a preclinical tool for the detection of plaques with intraplaque hemorrhage and its potential use in testing and monitoring of plaque-stabilizing drugs, our report has the potential to support technical developments for imaging technologies that will ultimately allow to risk stratify atherosclerotic plaques in patients and, in particular, to identify plaques that are prone to cause cardiovascular events. (nature.com)
Recent evidence suggests that the risk of clinical events is related not only to local factors within the atherosclerotic plaque (such as the state of the necrotic core or the fibrous cap), but also to blood-borne or systemic factors. (medscape.com)
1998. Atherosclerotic risks from chemicals: Part I. Toxicological observations and mechanisms of atherosclerosis. (cdc.gov)
Atherosclerosis is a condition in which patchy deposits of fatty material (atheromas or atherosclerotic plaques) develop in the walls of medium-sized and large arteries, leading to reduced or blocked blood flow. (msdmanuals.com)

Compared with hsCRP below the detection limit, elevated hsCRP (≥ 2.3 mg/L) was weakly associated with any coronary atherosclerosis (OR 1.15, 95% CI 1.07-1.24), coronary diameter stenosis ≥ 50% (OR 1.27, 95% CI 1.09-1.47), ≥ 4 segments involved (OR 1.13, 95% CI 1.01-1.26 ) and severe atherosclerosis (OR 1.33, 95% CI 1.05-1.69) after adjustment for age, sex and traditional risk factors. (lu.se)

Healthy lifestyle habits can help prevent atherosclerosis. (mayoclinic.org)

With the current study we demonstrated that from different important sites where atherosclerosis frequently occurs (carotid bifurcation, aorta, coronary arteries), the presence and amount of intracranial atherosclerosis seems to be the most important with regard to strokes. (medicalresearch.com)
Additionally, more research is needed on prevention and treatment of intracranial atherosclerosis. (medicalresearch.com)
Further research should also focus on preventing intracranial atherosclerosis in healthy populations. (medicalresearch.com)
Overall, intracranial atherosclerosis was significantly less prevalent in the LC group than in the matched control group (2.3% vs. 5.4%, P =0.002), whereas the prevalence of extracranial atherosclerosis was similar (4.4% vs. 5.8%, P =0.242). (e-cmh.org)
LC confers protection against intracranial atherosclerosis, and thrombocytopenia may be involved in this protective effect. (e-cmh.org)

Extensive research has proposed delimitation and control of the various, modifiable risk factors associated with its development and progress. (japt.gr)
Another reason is exposure to various modifiable risk factors that are responsible for at least 75% of all the CVDs. (who.int)
Contemporary worksite interventions to reduce CVD risk often combine individual behavior change with environmental and policy supports to address modifiable risk factors such as smoking, physical activity and nutrition. (cdc.gov)

New research suggests that chronic exposure to ambient ozone may raise the risk of atherosclerosis and harm arterial health. (medicalnewstoday.com)
This may indicate that the association between long-term exposure to ozone and cardiovascular mortality that has been observed in some studies is due to arterial injury and acceleration of atherosclerosis," comments Wang. (medicalnewstoday.com)
May reduce the risk of atrial fibrillation, sudden cardiac death, heart failure, venous thromboembolism, and peripheral arterial disease. (cdc.gov)

After adjusting for confounding factors, including smoking, BP and obesity, the researchers found the use of oral contraceptives for 10 years was associated with a 17 per cent increased risk of plaque in the carotid artery and a 28 per cent increased risk of plaque in the femoral artery. (gponline.com)
The prevalence of carotid atherosclerosis was calculated from 9 case-control studies, combining data from 9083 people, of whom 1979 had carotid artery plaques. (hivandhepatitis.com)

ABSTRACT This study aimed to estimate the frequency of the SNPs (+45T>G and +276G>T) genotypes and investigate the association between the two SNPs and adiponectin concentration, metabolic parameters and risk of T2DM in the Bahraini population. (who.int)

Although risk factors of occlusive acute mesenteric ischemia are well known, triggering factors of nonocclusive mesenteric ischemia (NOMI) remain unclear. (springeropen.com)
On the one hand, atherosclerosis could be considered as an additional risk factor for gut ischemia, but on the other hand, atherosclerosis may also limit the capacity of small vessels for vasocontraction. (springeropen.com)
However, in certain patients, a paradoxical vasoconstriction event ensues (4) such that this technique actually carries a risk of coronary ischemia. (escardio.org)

A family history of blood clots or an inherited blood-clotting disorder (such as one that makes your blood clot more easily) can put you at risk for developing blood clots. (healthline.com)

The presence of preclinical atherosclerosis increases global cardiovascular risk - preclinical atherosclerosis can be considered an emerging determinant in assessing global cardiovascular risk. (escardio.org)
Smoking and secondhand smoke damage blood vessels, which directly increases the risk of atherosclerosis. (sharecare.com)
Pregnancy also increases your risk for blood clots. (healthline.com)
LA increases the risk of CVA and dementia. (magiran.com)
There was moderate quality evidence from two studies suggesting that varenicline increases ST abstinence rates (risk ratio [RR] 1.34, 95% confidence interval (CI) 1.08 to 1.68, 507 participants). (who.int)

Berenson and colleagues report the findings from the Bogalusa Heart Study, which examined the influence of multiple cardiovascular risk factors on the extent of atherosclerosis in young people. (aafp.org)
The findings suggest that oral contraceptives could be adding to the global burden of atherosclerosis. (gponline.com)
By the early 1980s I had treated hundreds of coronary patients in different Cardiac Rehabilitation programs and could see the "Lipid Theory of Atherosclerosis" was not valid as other studies from around the world confirmed our findings at Rancho Los Amigos Hospital where I worked for nine years. (roadbikerider.com)
Moreover, our findings indicate that its contribution to the proportion of all strokes is greater than that of atherosclerosis in other vessel beds that are further away from the brain. (medicalresearch.com)
The researchers wrote in conclusion, "Overall, our findings support the potential role of healthy sleeping in protecting against atherosclerosis. (belmarrahealth.com)
Together, these findings might lead to widespread prevention of atherosclerosis - in its preclinical stage, which would have a major global health impact. (escardio.org)
Previous studies have produced inconsistent findings regarding the risk of cardiovascular disease in people with hepatitis C virus (HCV). (hivandhepatitis.com)

These studies were inconsistent in their recording of risk factors, so it was not possible to come up with a pooled estimate that controlled for the prevalence of risk factors. (hivandhepatitis.com)
The two cohorts were matched for cerebrovascular risk factors, and the prevalence of atherosclerosis in major intracranial and extracranial arteries was compared in 755 matched pairs. (e-cmh.org)
It is not surprising that studies on the prevalence of sexual risk assessment are generally concerned with clinic populations (i.e., those who may be most at risk for HIV/STI infection). (cdc.gov)
to monitor the prevalence and trends in major cardiovascular conditions and risk factors in the U.S. (cdc.gov)

DISCUSSION: The weight of the evidence that we were able to identify suggests that occupational stress results in an increased risk of atherosclerosis, assessed via CIMT. (cdc.gov)

Collectively, the extent of fatty-streak lesions in coronary arteries was 8.5 times greater in persons with three or four risk factors, and the extent of fibrous plaques in the arteries was 12 times as great, compared with persons with no identifiable risk factors. (aafp.org)
56.1% of the patients in the FRS-based low to intermediate risk groups were found to have carotid plaques. (bmj.com)
The association to high-risk noncalcified plaques, although unlikely through a causal pathway, could explain the relationship between hsCRP and clinical coronary events in numerous studies. (lu.se)
Atherosclerosis, the most common type, means hardening related to plaques, which are deposits of fatty materials. (msdmanuals.com)

Multidetector computed tomography may be a useful non-invasive technique to detect silent coronary artery disease in patients with peripheral preclinical atherosclerosis. (escardio.org)
Aim To investigate the usefulness of carotid atherosclerosis assessment in cardiovascular risk stratification of patients with psoriatic disease compared with the Framingham Risk Score (FRS). (bmj.com)
55.9% of the patients from the FRS-based intermediate risk category were reclassified into an ultrasound-based high-risk category, while 47.1% of the patients in the FRS-based low-risk category were reclassified into a higher US-based risk group. (bmj.com)
The extent of reclassification into a higher risk category was particularly high among patients with PsA. (bmj.com)
While traditional CV risk factors that are prevalent in patients with psoriatic disease play an important role in the pathogenesis, they do not fully explain this excessive risk. (bmj.com)
They found that experimentally reducing the expression of DNMT3A or TET2 in the normal blood cells had similar results to blood cells that had loss of function mutations and blood cells from atherosclerosis patients--an increased inflammatory response. (news-line.com)
Our results suggest that atherosclerosis is not a risk factor for NOMI in critically ill patients. (springeropen.com)
IMT is a non-invasive diagnostic and prognostic test in LA. The aim of this study was evaluate the carotid IMT and LA in diabetic patients as atherosclerosis surrogate marker. (magiran.com)
Dental prophylaxis is often recommended for patients following joint replacement, whereas any vulnerable areas for infection in the body can pose a potential risk. (aapc.com)
Moreover, traditional, hepatic, and coronary variables related to cerebral atherosclerosis were assessed in cirrhotic patients. (e-cmh.org)
Results Across all the 1 267 159 patients in the validation dataset, the 50th, 75th, 90th, and 95th centile values for lifetime risk were 31%, 39%, 50%, and 57% respectively. (bmj.com)
Of the 10% of patients in the validation cohort classified at highest risk with either the lifetime risk model or the 10 year risk model, only 18 385(14.5%) were at high risk on both measures. (bmj.com)
Patients identified as high risk with the lifetime risk approach were more likely to be younger, male, from ethnic minority groups, and have a positive family history of premature coronary heart disease than those identified with the 10 year QRISK2 score. (bmj.com)
Conclusions Compared with using a 10 year QRISK2 score, a lifetime risk score will tend to identify patients for intervention at a younger age. (bmj.com)
1 National policies now support targeting of interventions to reduce risk of cardiovascular disease among high risk patients. (bmj.com)
Applying this 20% risk threshold for intervention may not identify younger patients who, because of their age, have a low absolute 10 year risk but who have a high relative risk compared with their peers. (bmj.com)
Some argue that younger patients with an adverse risk profile may have more to gain during their lifetime if interventions are started at a younger age rather than waiting until they cross the 20% threshold. (bmj.com)
Health care providers who talk to their patients about aspects of their sexual experience may make them aware of behaviors that may increase their risk, such as not using condoms and having multiple sexual partners. (cdc.gov)
Nous avons génotypé les deux polymorphismes mononucléotidiques du gène ADIPOQ chez 140 patients atteints de DNID sans lien de parenté et 66 témoins non diabétiques en recourant à l'analyse du polymorphisme de longueur des fragments de restriction par réaction en chaîne de polymérase. (who.int)
Lipid-lowering therapy is important for secondary prevention for patients with known cardiovascular disease, as well as for primary prevention for those at increased risk. (medscape.com)
As suboptimal control keeps them at continued cardiovascular risk, such patients should be thoroughly evaluated for true statin intolerance , and adjunctive or alternative therapies should be considered. (medscape.com)

History of clinical AIDS and HIV viral load were not significantly associated with carotid atherosclerosis. (elsevierpure.com)

The ARIC Study was designed to investigate the etiology and clinical outcomes of atherosclerosis. (wikipedia.org)
Mayo Clinic cardiologists, cardiovascular surgeons and others perform clinical research to develop new treatments and approaches to reduce the risk of heart attack and other medical conditions caused by atherosclerosis. (mayoclinic.org)
Therefore, the presented reference values represent a basis for clinical evaluation and for future research on risk assessment of diseases associated with increased CRP levels among children. (nature.com)

Atherosclerosis can also impact the peripheral arteries, which supply oxygenated blood to the legs, arms, and pelvis and the renal arteries, which supply blood to the kidneys. (nghs.com)
Atherosclerosis and endothelial dysfunction are diffuse disease processes affecting coronary and peripheral arteries, hence, the physiological basis in assessing endothelium-dependent vasomotion in peripheral vessels. (escardio.org)
High levels of serum triglycerides help determine the risk for coronary heart disease (CHD) and peripheral atherosclerosis. (cdc.gov)

Considering that atherosclerosis is closely related to cardiovascular events, has made it the object of many studies, whether, its harmful impact on cerebral function leads to dementia and Alzheimer's disease. (japt.gr)
ObjectiveTo determine the risk of dementia after the development of late-onset epilepsy.MethodsWe used data from the Atherosclerosis Risk in Communities (ARIC) cohort study, which started in 1987 to 1989 with 15,792 mostly Black and White men and women from 4 US communities. (johnshopkins.edu)
We used a Cox proportional hazards regression model to evaluate associations between LOE and dementia through 2017 as ascertained from neuropsychological testing, interviews, and hospital discharge surveillance, and we used multinomial logistic regression to assess the risk of dementia and mild cognitive impairment in the subset with full neuropsychological assessments available. (johnshopkins.edu)
The median time to dementia ascertainment after the onset of LOE was 3.66 years (quartile 1-3, 1.28-8.28 years).InterpretationThe risk of incident dementia is substantially elevated in individuals with LOE. (johnshopkins.edu)
Further work is needed to explore causes for the increased risk of dementia in this growing population. (johnshopkins.edu)

The first step in the prevention of HIV and other STIs is to identify the people who may be at risk. (cdc.gov)
A sexual risk assessment is a primary prevention tool that can help identify persons at risk of HIV/STIs. (cdc.gov)
Another reason is exposure to behavioural and physiological risk factors (Figure 1) which are responsible for 75% of CVDs.1 These risk factors have been prioritized according to their impact on mortality and morbidity, possibility of modification through primary prevention, and quantification by available easy standardized methods. (who.int)
Control of these risks constitutes the cornerstone of prevention of CVD. (who.int)

The teams applied genetic engineering tools and cell imaging to examine cells from people with normal cells, those with loss of function mutations in DNMT3A or TET2 expression, and those with atherosclerosis. (news-line.com)

Atherosclerosis refers to the buildup of plaque in the arteries. (sharecare.com)

Infections and inflammatory conditions also contribute to endothelial injury and atherosclerosis. (medscape.com)

The purpose of our study was to evaluate whether abdominal atherosclerosis is a risk factor for NOMI. (springeropen.com)
Reduces the risk of abdominal aortic aneurysm, with risk reduction increasing with time since cessation. (cdc.gov)

The ARIC Study is a prospective cohort study initiated in 1987 to study cardiovascular disease risk factors and natural history. (biomedcentral.com)

A specific condition is defined as risk factor when it is possible, on the basis of a strong statistical association, to relate it to the incidence of new cases of disease and if it is clinically demonstrated that new disease cases can be reduced by correcting the same risk factor. (escardio.org)

Atherosclerosis can affect the medium-sized and large arteries of the brain, heart, kidneys, other vital organs, and legs. (msdmanuals.com)

editor's note: Data from the Bogalusa Heart Study certainly suggest that known risk factors for coronary disease begin to have an effect in early adulthood and possibly even in childhood. (aafp.org)

These immunosuppressive properties of THC were confirmed in vitro, with spleen cells extracted from the mice showing limited proliferation and impaired production of interferon-, a cytokine involved in atherosclerosis, and reduced leukocyte migration. (medscape.com)

The lesions were examined and graded visually by three pathologists who were unaware of the risk-factor status of the deceased person. (aafp.org)
Smoking is a particularly significant risk factor because it can both increase the risk of plaque forming in the first place and accelerate the growth of plaque once it begins. (nghs.com)
Any cardiovascular risk factor, no. (cdc.gov)
Being immobile, or not moving for a long period of time, is another risk factor. (healthline.com)
Furthermore, atherosclerosis is being studied and, as an independent risk factor, which may influence cognitive function, regardless of cerebral infarcts. (japt.gr)
Coronary artery calcium (CAC) score ≥100 was the only predictive factor for both intracranial and extracranial atherosclerosis (adjusted ORs, 4.06 and 5.43, respectively). (e-cmh.org)
in addition, smoking is a main risk factor for cancer. (who.int)
More effective risk factor intervention combined with better management of acute cardiovascular events have decreased age-related cardiovascular mortality by over 30% over the last decades. (lu.se)
Clinicians, however, usually do not consider occupational stress as a preventable risk factor for CVD. (cdc.gov)

This study aimed to examine the association between hsCRP and coronary computed tomography angiography (CCTA)-detected coronary atherosclerosis in a population-based cohort. (lu.se)

I'm less concerned with diagnosing atherosclerosis than I am with treating risk factors and preventing serious complications," he says. (sharecare.com)
For men, erectile dysfunction (ED) is an early warning sign that you may be at higher risk for atherosclerosis and its complications. (medlineplus.gov)
Atherosclerosis can cause other health problems, or complications. (medlineplus.gov)
Hospital - at risk of cardiovascular complications? (who.int)
Poor glycaemic control, dyslipidaemia and HT are common in diabetic children, putting them at risk of cardiovascular complications in adulthood. (who.int)

The Atherosclerosis Risk in Communities (ARIC) Study is a multi-site, prospective, biracial cohort study funded by the National Heart, Lung, and Blood Institute of the National Institutes of Health. (wikipedia.org)
The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. (wikipedia.org)
Metabolomics and incident hypertension among blacks: the atherosclerosis risk in communities study. (bcm.edu)
aged, 45-64 years) from the Atherosclerosis Risk in Communities study, whose metabolome was measured in serum collected at the baseline examination and analyzed by high-throughput methods. (bcm.edu)
We leveraged data from the Atherosclerosis Risk in Communities Study. (bvsalud.org)
Thirteen thousand eight hundred seventy-six community -dwelling blacks and whites aged 45-64 years from the Atherosclerosis Risk in Communities Study. (bvsalud.org)

Nevertheless, endothelial function has, for the time being, been demonstrated to be a marker for risk of cardiovascular events in high risk groups only. (escardio.org)

Risk factors for atherosclerosis alone aren't accurate enough in predicting cardiovascular disease in adults with no history of atherosclerosis disease. (escardio.org)
The presence of one or more risk factors for atherosclerosis (ATS) is associated with the development of cardiovascular disease (CVD). (escardio.org)
The relationship between atherosclerosis and coronary heart disease is complex. (aafp.org)
They believe their data support the Framingham Study, which determined that multiple cardiac risk factors have a synergistic effect on morbidity and mortality from cardiovascular disease. (aafp.org)
In addition, cigarette smoking appears to adversely affect the extent of coronary disease in persons with other risk factors. (aafp.org)
However, interventions such as counseling against tobacco use and encouraging healthy dietary habits and exercise appear to be reasonable and potentially effective ways to reduce the future risk of heart disease. (aafp.org)
Coronary artery disease is caused by atherosclerosis or hardening of the arteries due to old age. (singhealth.com.sg)
Atherosclerosis is a slow, progressive disease that may start as early as childhood. (hopkinsmedicine.org)
Chronic obstructive pulmonary disease (COPD) independently associates with an increased risk of coronary artery disease (CAD), but it has not been fully investigated whether this co-morbidity involves shared pathophysiological mechanisms. (ox.ac.uk)
Atherosclerosis is a gradual artery disease. (wellnessofhealth.com)
Coronary artery disease (CAD): Atherosclerosis damages the coronary arteries, which feed blood to the heart muscle. (wellnessofhealth.com)
The coronary calcium score for example, has proven added value in the prediction of acute cardiac disease beyond the Framingham risk score profile. (medicalresearch.com)
Reduces the risk of disease and death from CVD. (cdc.gov)
Reduces the risk of coronary heart disease, with risk falling sharply 1 to 2 years after cessation and then declining more slowly over the longer term. (cdc.gov)
Mayo Clinic researchers also study novel and emerging factors that increase the risk of heart disease. (mayoclinic.org)
Objective To develop, validate, and evaluate a new QRISK model to estimate lifetime risk of cardiovascular disease. (bmj.com)
9 10 11 12 Lifetime risks which measure the cumulative risk of developing a disease during the remainder of an individual's life 13 would reflect this relatively high risk and, given that lifetime risk estimates provide assessment over the full life course, they may provide a more appropriate assessment of future risks than estimates limited to 10 years, particularly at younger ages. (bmj.com)
The most important cardiovascular diseases (CVDs) in the African Region are those related to atherosclerosis, cardiomyopathies and rheumatic heart disease. (who.int)
5. The WHO STEPwise approach to surveillance of noncommunicable diseases in general and cardiovascular disease in particular (otherwise known as STEPS) is based on community evaluation of eight risk factors (see Figure 1). (who.int)
Improving continuity and content of care during postpartum may improve uptake of preventive behaviors among postpartum pa- tients at risk of heart disease. (cdc.gov)
Cardiometabolic heath conditions are critical determinants of peri- plications and future heart disease, there are documented gaps in natal risk. (cdc.gov)

Anatomy34

Organisms7

Diseases51

Chemicals and Drugs82

Analytical, Diagnostic and Therapeutic Techniques and Equipment41

Psychiatry and Psychology1

Phenomena and Processes36

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture1

Information Science2

Named Groups6

Health Care23

Geographicals6

Subclinical11

Progression17

Arteriosclerosis4

Stroke35

Development of atherosclerosis3

Inflammation15

Diabetes12

Vascular8

Plaque buildup1

Intima-media thi3

Cholesterol21

Contribute to atherosclerosis2

Treatment of atherosclerosis1

Severity of atherosclerosis4

Target for atherosclerosis1

Symptoms14

Atherosclerotic16

Severe atherosclerosis1

Prevent atherosclerosis1

Intracranial atherosclerosis5

Modifiable risk factors3

Arterial3

Carotid artery2

Abstract1

Ischemia3

Blood clot1

Increases5

Findings7

Prevalence4

CIMT1

Plaques4

Patients21

Significantly1

Clinical3

Peripheral3

Dementia5

Prevention4

Genetic1

Buildup of plaque1

Inflammatory1

Abdominal2

Cardiovascular disease risk factors1

Clinically1

Medium-sized1

Factors for coronary disease1

Cytokine1

Factor9

Angiography1

Complications5

Communities6

Marker1

Disease21