• Patients
  • Patients taking aspirin were aged 67.5 years, on average, and those who weren't were aged 67.6 years, on average. (medicalnewstoday.com)
  • In reviewing more than 1,200 cases of coronary episodes, French researchers found 51 patients who suffered heart attacks or other severe coronary problems less than one week after they stopped using aspirin. (hsionline.com)
  • The French team told Reuters news service that doctors should not advise their coronary patients to stop using aspirin, and even stated that aspirin therapy "cannot be safely stopped in any case. (hsionline.com)
  • Raymond DuBois, M.D., Ph.D , MD Anderson's provost and executive vice president and a professor of cancer biology and cancer medicine, shares his insights on the study's significance and addresses questions about aspirin dose, and how cancer patients should respond to this news. (mdanderson.org)
  • Elderly patients should not panic over reports that taking aspirin long-term increases the risk of stomach and gut bleeding, doctors said. (dunstabletoday.co.uk)
  • Professor Helen Stokes-Lampard, Chair of the Royal College of GPs, said: "Aspirin is known to be an inexpensive and effective drug for patients who have suffered a stroke or heart attack, but we have known for some time that there are risks involved with its long-term use - and this research shows, it is particularly the case for our older patients. (dunstabletoday.co.uk)
  • The study does reassure us that in most cases, aspirin is still the most appropriate course of treatment for patients, but highlights the importance of managing its use carefully and effectively and that some patients may require additional medication to protect them. (dunstabletoday.co.uk)
  • Prescribing is a core skill for GPs and patients can be assured that their family doctor will only prescribe medication following a full and frank discussion with the patient, outlining the potential risks and side effects associated with the drugs. (dunstabletoday.co.uk)
  • It is also important that patients who are prescribed aspirin see a healthcare professional for regular medication reviews, and that they use this opportunity to raise any concerns they may have. (dunstabletoday.co.uk)
  • Patients who regularly take aspirin - either as prescribed by their doctor or self-medicated - should not panic as a result of this research. (dunstabletoday.co.uk)
  • Combined therapy with clopidogrel and aspirin can substantially reduce the risk of stroke in patients not suitable for warfarin therapy, say researchers. (pulsetoday.co.uk)
  • Their randomised trial in over 7,500 patients with atrial fibrillation and at least one risk factor for stroke, found patients receiving clopidogrel and aspirin had a 11% decrease in major vascular events, compared with those just taking aspirin. (pulsetoday.co.uk)
  • The reduction was mainly due to a 28% risk reduction in stroke in this population of patients who, for various reasons, were unsuitable for warfarin therapy. (pulsetoday.co.uk)
  • This new study - published online in The New England Journal of Medicine - suggests clopidogrel should be added to aspirin therapy in the 40% of patients who are not suitable for warfarin therapy - such as those with a bleeding risk or those likely not to be compliant with therapy. (pulsetoday.co.uk)
  • Professor John Camm, professor of clinical cardiology at St George's Hospital Medical School, London, said the study showed this difficult group of patients could have better thrombotic control with clopidogrel than they could get from aspirin alone. (pulsetoday.co.uk)
  • Professor Camm said there were concerns over an increased risk of bleeding with the combination, but these were trivial compared with the thrombo-embolic risk in these patients. (pulsetoday.co.uk)
  • Moreover, aspirin taken in conjunction with chemotherapy or radiotherapy can help further reduce death in bowel cancer patients by about 15% and may help patients with other forms of cancer as well. (secondopinionnewsletter.com)
  • The study, which was primarily designed to assess post-operative adjuvant chemotherapy in stage III colon cancer patients, also demonstrated a benefit to using aspirin in people who have already been diagnosed with colon cancer. (rxpgnews.com)
  • Consistent aspirin use was reported by 8.7% of the patients (most of whom took 81 mg to 325 mg per day), while 4.3% of patients reported regular use of celecoxib or rofecoxib. (rxpgnews.com)
  • Most hospitalized medical patients have at least 1 risk factor for thrombosis that progresses to thromboembolism and this risk persists weeks after discharge. (wikipedia.org)
  • However, the annual incidence of major bleeding due to low-dose aspirin is modest-only 1.3 patients per thousand higher than what is observed with placebo treatment. (wikipedia.org)
  • Treatment of approximately 800 patients with low-dose aspirin annually for cardiovascular prophylaxis will result in only 1 additional major bleeding episode. (wikipedia.org)
  • Dentists should be aware of the risk of prolonged bleeding time in patients taking antiplatelet drugs when planning dental treatments that are likely to cause bleeding. (wikipedia.org)
  • This particular study had an 8.4% prevalence of acute coronary syndrome, which means the positive predictive value of being a male with chest pain and having coronary syndrome is 9.6% and negative predictive value is 93.2% ( click here[permanent dead link] to adjust these results for patients at higher or lower risk of acute coronary syndrome). (wikipedia.org)
  • Members of the Consortium are especially interested in testing simple, low-risk, and inexpensive treatments that have the potential to markedly improve patients' surgical experiences. (wikipedia.org)
  • He is responsible for the clinical development of high sensitivity C-reactive protein (hsCRP), a marker of inflammation, that is used to evaluate the risk of heart attack and stroke, and coined the term "residual inflammatory risk" to describe patients who are at risk due to vascular inflammation rather than high cholesterol levels. (wikipedia.org)
  • In 2013, Ridker and Nancy Cook noted that the calculator used in the US guidelines for heart disease prevention and treatment over-estimated risk, an important issue since this risk calculator is the primary tool used to determine which patients will get treated with statin therapy and aspirin. (wikipedia.org)
  • Ridker and Cook have thus advocated for the risk calculator to be re-calibrated to better reflect the concepts of "personalized medicine" so that the right treatments can be given to the right patients and so that the benefits as well as hazards of treatment can be better reflected for patient care. (wikipedia.org)
  • prevention
  • In addition, taking aspirin has significant risks, and thus shouldn't be part of primary prevention unless you're at moderate to high risk of heart disease. (medicinenet.com)
  • In addition to these, an increasing number of studies have been recently pointing to another prevention strategy: the use of aspirin . (medicalnewstoday.com)
  • In a BBC News account of the study the medical director of the British Heart Foundation, Professor Peter Weissberg, noted that given the UT study results, a clinical trial to test effects of low-dose aspirin therapy in older people "should be undertaken before aspirin is advocated for primary prevention of heart disease in the elderly community. (hsionline.com)
  • The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening and diagnostic services. (mdanderson.org)
  • Currently, the American Diabetes Association (ADA) recommends low-dose aspirin for primary prevention in people with diabetes who are at risk for cardiovascular disease--but this will be changing. (cnn.com)
  • In 2004, a U.S. Food and Drug Administration advisory panel rejected the idea of using aspirin for primary prevention. (cnn.com)
  • Editor-in-Chief of the Journal, Susan G. Kornstein, MD, commented on the findings saying, "based on this survey, it is evident that the majority of women for whom aspirin is recommended for prevention of cardiovascular disease are not following national guidelines. (prweb.com)
  • Aspirin is known to help in the prevention of arthritic inflammations, heart attacks, strokes and several types of cancer along with headaches. (medindia.net)
  • This is the first study to examine whether aspirin might influence the growth of specific types of tumors, said Dr. Raymond DuBois, director of cancer prevention at Vanderbilt University's Vanderbilt-Ingram Cancer Center. (onlineathens.com)
  • Key topics include the usage of inflammation inhibitors (e.g., aspirin) in cancer prevention and prognosis. (wikipedia.org)
  • Prevention measures or interventions are usually begun after surgery as people are at higher risk due to immobility. (wikipedia.org)
  • One of the goals of blood clot prevention is to limit venous stasis as this is a significant risk factor for forming blood clots in the deep veins of the legs. (wikipedia.org)
  • While Ridker is an advocate of statin therapy for heart disease prevention, his group was also demonstrated that statin therapy is associated with a small increase in the risk of developing diabetes. (wikipedia.org)

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  • stroke
  • Aspirin is not effective in protecting a person from a first cardiac event -- a heart attack or stroke ," said study author Dr. Antonio Nicolucci, head of the department of clinical pharmacology at nonprofit biomedical research organization Consorzio Mario Negri Sud in Santa Maria Imbaro, Italy. (medicinenet.com)
  • Interrupting aspirin treatment may raise the risk of having a stroke or heart attack. (medicalnewstoday.com)
  • An aspirin a day has been shown to lower the risk of a first heart attack in men and a first stroke in women, who are at increased risk for these events. (harvard.edu)
  • As a consequence of the above, people with untreated polycythemia vera are at a risk of various thrombotic events (deep venous thrombosis, pulmonary embolism), heart attack and stroke, and have a substantial risk of Budd-Chiari syndrome (hepatic vein thrombosis), or myelofibrosis. (wikipedia.org)
  • In 1997, Ridker showed that elevated levels of hsCRP and interleukin-6 in healthy individuals were a major risk marker for future heart attack, stroke, diabetes, and cardiovascular death, independent of traditional risk factors. (wikipedia.org)
  • This work, largely funded by the National Institutes of Health, eventually led to the design and conduct of the multi-national JUPITER trial which in 2008 demonstrated that individuals with elevated hsCRP levels could reduce by half their risk of future heart attack or stroke by taking statin therapy. (wikipedia.org)
  • rofecoxib
  • Further data, from the APPROVe trial, showed a statistically significant relative risk of cardiovascular events of 1.97 versus placebo-which caused a worldwide withdrawal of rofecoxib in October 2004. (wikipedia.org)
  • cancer
  • There are a number of things that we can do to prevent cancer, including leading a healthy lifestyle and having regular screenings if we are at risk. (medicalnewstoday.com)
  • More specifically, aspirin users were 47 percent less likely to have liver and esophageal cancer, 38 percent less likely to have stomach cancer, and 34 percent less likely to have pancreatic cancer. (medicalnewstoday.com)
  • 7 times a week showed a 26% risk reduction for developing the type of breast tumor that is stimulated by the hormone estrogen, the most common form of breast cancer. (pharmacytimes.com)
  • In this study, researchers compared 1442 women with all forms of breast cancer with 1420 women without the disease and conducted interviews regarding their use of aspirin. (pharmacytimes.com)
  • Association of frequency and duration of aspirin use and hormone receptor status with breast cancer risk. (pharmacytimes.com)
  • Can Aspirin Reduce Risk for Cancer Metastasis? (mdanderson.org)
  • The authors of the study said the findings are tantalizing but that more research is needed before doctors can recommend that women take aspirin to ward off breast cancer. (onlineathens.com)
  • Women in the study who used aspirin at least four times a week for at least three months were almost 30 percent less likely to develop hormone-fueled breast cancer than women who used no aspirin. (onlineathens.com)
  • But I disagree that the risks of stomach bleeding as well as stomach ulcers are worth the benefit - even though I understand that they're a lot less likely to be fatal than cancer and heart disease. (secondopinionnewsletter.com)
  • But taking two per day can also help lower your risk of cancer and heart disease. (secondopinionnewsletter.com)
  • Previous studies in both animals and people have shown that regular aspirin use may reduce the risk of developing colon cancer and benign growths called polyps. (rxpgnews.com)
  • Animal studies have also suggested that the benefits of aspirin may extend to people who already have colon cancer, by reducing their risk of recurrence. (rxpgnews.com)
  • After a median of 2.4 years of follow-up, the risk of colon cancer recurrence was 55% lower and the risk of death was 48% lower among the aspirin users compared with non-users. (rxpgnews.com)
  • People with colon cancer who are interested in taking aspirin should first speak with their doctors. (rxpgnews.com)
  • Aspirin and cancer risk is in the news again-and the link is still unclear. (cancerconnect.com)
  • The data continues to roll in regarding aspirin and cancer. (cancerconnect.com)
  • In fact, those taking aspirin were less than half as likely to die from prostate cancer over a 10-year period-the prostate cancer death rate among the men taking aspirin was 3 percent compared to 8 percent among the men who were not. (cancerconnect.com)
  • The researchers concluded that regular aspirin use is associated with reduced prostate cancer-specific mortality. (cancerconnect.com)
  • Both studies serve to further shine the light on the relationship between aspirin use and cancer incidence and mortality. (cancerconnect.com)
  • Research will likely continue-but for now, it appears that aspirin does not reduce the risk of breast cancer, but may reduce the risk of death from prostate cancer. (cancerconnect.com)
  • Aspirin use and the risk of prostate cancer mortality in men treated With prostatectomy or radiotherapy. (cancerconnect.com)
  • The MALOVA (MALignant OVArian cancer) study is a multidisciplinary Danish study of Ovarian Cancer and encompasses epidemiology, lifestyle factors, biochemistry, and molecular biology with the purpose of identifying risk factors and prognostic factors for Ovarian Cancer. (wikipedia.org)
  • inhibits
  • Aspirin and Triflusal irreversibly inhibits the enzyme COX, resulting in reduced platelet production of TXA2 (thromboxane - powerful vasoconstrictor that lowers cyclic AMP and initiates the platelet release reaction). (wikipedia.org)
  • Aspirin inhibits platelet aggregation by inhibiting the action of thromboxane A2. (wikipedia.org)
  • Study
  • A large-scale study finds that the long-term use of aspirin cuts the chances of developing digestive cancers almost in half. (medicalnewstoday.com)
  • But in a study published in the June 6, 2012 Journal of the American Medical Association , this practice increased the risk of major bleeding in the digestive tract or brain by 55% in people without diabetes. (harvard.edu)
  • Study participants with diabetes had a 36% higher risk of bleeding, and aspirin use did not change this risk. (harvard.edu)
  • In the e-Alert "Pain Takes a Holiday" (9/8/03) I told you about a 15-month study of almost 2,000 subjects that showed how those whose diets included the highest fruit intake had more than 70 percent reduced risk of heart attack and other cardiac problems compared with those who ate the least amount of fruit. (hsionline.com)
  • The study and concurrent survey showed that women who were more likely to use aspirin if they had a family history of cardiovascular disease or had high cholesterol. (prweb.com)
  • Study authors have decided more educational programs are needed to increase awareness regarding how aspirin can be used as a preventative for heart disease among women. (prweb.com)
  • Aspirin, the magic drug present in almost every medicine cabinet, may help in easing out prostate problem, according to a study by Minnesota's Mayo Clinic. (medindia.net)
  • The study published in the American Journal of Epidemiology says that Aspirin may also reduce the risk of contracting the enlarged prostate by 50 percent. (medindia.net)
  • In 2005, a head to head study dashed hopes that the clopidogrel-aspirin combination could replace warfarin, after it was stopped prematurely because of a significant difference in preventing vascular events was observed in favour of warfarin. (pulsetoday.co.uk)
  • regimen
  • You begin an aspirin regimen to protect your heart, but if you stop, you stand a chance of prompting a dangerous coronary episode. (hsionline.com)
  • diabetes
  • The risk-benefit ratio should be carefully evaluated for each patient, based on individual risk factors such as hypertension, elevated lipids, obesity, diabetes and a family history of heart disease, Nicolucci said. (medicinenet.com)
  • Diabetes can dramatically increase the risk of developing heart disease. (cnn.com)
  • Kirkman stresses that people with diabetes who are taking aspirin--and have no history of heart attack--should talk to their doctor and see if he or she recommends continuing the therapy. (cnn.com)
  • According to Nissen, 'the right person would likely have a cluster of risk factors for heart disease, such as diabetes, smoking, high cholesterol, and high blood pressure,' he says. (cnn.com)
  • Dementia can be prevented by reducing the risk factors for vascular disease (e.g. diabetes, high blood pressure, obesity, smoking, and physical inactivity) and depression. (wikipedia.org)
  • clopidogrel
  • But if they are not on it, or are having some difficulties, then the combination of clopidogrel and aspirin could provide some advantage,' he said. (pulsetoday.co.uk)
  • Often a combination of aspirin plus an ADP/P2Y inhibitor (such as clopidogrel, prasugrel, ticagrelor, or another) is used in order to obtain greater effectiveness than with either agent alone. (wikipedia.org)
  • suggests
  • Aspirin could prevent digestive cancers, especially in the elderly, suggests new research. (medicalnewstoday.com)
  • Topical salicylic acid is common in many over-the-counter dermatological agents and the lack of adverse reports suggests a low risk. (wikipedia.org)
  • acetaminophen
  • As with all medications containing paracetamol (acetaminophen), concomitant use with alcohol carries a significant risk of hepatotoxicity. (wikipedia.org)
  • doses
  • The combination of paracetamol with aspirin also creates the risk of renal papillary necrosis if large doses are taken chronically. (wikipedia.org)
  • take
  • The authors recommended that anyone who has a history of internal bleeding, who takes drugs that increase the risk of bleeding, or who has an elevated risk due to advanced age not take aspirin to prevent heart disease. (harvard.edu)
  • However, he cautioned that not everyone should automatically take aspirin. (bmj.com)
  • reduce
  • Another meta-analysis showed that not only did aerobic exercise reduce the risk of dementia but it may also slow cognitive decline in those with dementia. (wikipedia.org)
  • Moderate alcohol consumption can possibly reduce the risk of vascular disease and dementia because it can increase blood levels of HDL cholesterol and weakens blood-clotting agents such as fibrinogen, which offers some protection against heart attacks and small subclinical strokes that together can ultimately damage the brain. (wikipedia.org)
  • Researchers
  • Researchers at the University of Tasmania School of Medicine (UT) in Australia designed an epidemiological model to assess aspirin risks and benefits among older people . (hsionline.com)
  • But researchers said people should not rush out to buy aspirin. (medindia.net)
  • It's helpful that the researchers suggest action to mitigate this risk - the prescription of a proton pump inhibitor (PPI) as a secondary drug - but this does raise a number of health implications. (dunstabletoday.co.uk)
  • So why do researchers continue to recommend aspirin use? (secondopinionnewsletter.com)
  • deep vein throm
  • Risk assessment and intervention for those with one or more episodes of deep vein thrombosis or blood clots in the veins utilizes the Well's test. (wikipedia.org)
  • cancers
  • Taking 75 mg of aspirin every day for five years or more reduces the risk of dying from a range of common cancers, a review of randomised trials has found. (bmj.com)
  • protective
  • According to articles in The Lancet , the protective effect occurs within 3-5 years of beginning aspirin use. (mdanderson.org)
  • Results of one meta-analysis, which investigated the relationship between physical activity and risk of cognitive decline in people without dementia, showed exercise had a significant and consistent protective effect against cognitive decline, with high levels of physical activity being most protective. (wikipedia.org)
  • medicine cabinet
  • Although it's commonly found in the household medicine cabinet, aspirin is not a simple drug," said Dr. Christopher Cannon, a cardiologist at Brigham and Women's Hospital in Boston and a professor of medicine at Harvard Medical School. (medicinenet.com)
  • reduces
  • Since vascular dementia is the second most common form of dementia (after Alzheimer's disease), reducing the risk of cerebrovascular disease also reduces the risk of dementia. (wikipedia.org)
  • benefit
  • As reported in an online edition of the British Medical Journal, the model showed that while heart attacks and ischaemic strokes may have been prevented, this benefit was offset by a significant number of subjects with sharply increased risk of bleeding in the brain and/or GI tract. (hsionline.com)
  • The Journal of Women's Health has shown evidence that less than half of the women who could benefit from aspirin are taking it. (prweb.com)
  • The benefit of treating those who are at low risk of developing blood clots may not outweigh the higher risks of significant bleeding. (wikipedia.org)
  • Each drug has a benefit-risk profile and balancing the risk of no treatment with the competing potential risks of various therapies is the clinician's responsibility. (wikipedia.org)
  • treatment
  • Participants completed surveys about their use of aspirin and other medications midway through therapy and six months after completion of treatment. (rxpgnews.com)
  • it responds rapidly to treatment with aspirin. (wikipedia.org)
  • Identify the likelihood and risk of dental treatment causing bleeding complications. (wikipedia.org)
  • Aspirin/paracetamol/caffeine is a combination drug for the treatment of pain, especially tension headache and migraine. (wikipedia.org)
  • chronic
  • Repeated concussions may also increase the risk in later life of chronic traumatic encephalopathy, Parkinson's disease, or depression. (wikipedia.org)
  • lower
  • Subjects who consumed vegetables three or more times each week had approximately 70 percent lower heart attack risk than those who ate no vegetables at all. (hsionline.com)
  • Aspirin regimens have already been proven to lower the risk of heart attacks and high blood pressure. (yahoo.com)
  • Further, between 1998 and 2005, Ridker showed that individuals with elevated hsCRP but low levels of cholesterol were at substantial risk and that statin drugs used to lower cholesterol also lowered hsCRP and thus had important anti-inflammatory properties. (wikipedia.org)
  • increase
  • Although aspirin can prevent clots, which cause about 80 percent of strokes, it may increase the risk of hemorrhagic strokes, which are caused by bleeding in the brain. (cnn.com)
  • An increase in antiplatelet effect would increase the risk of bleeding and results in prolonged or excessive bleeding. (wikipedia.org)
  • reduction
  • On average, for every additional piece of fruit consumed each day, subjects showed a 10 percent reduction in coronary risk. (hsionline.com)
  • drug
  • Television advertisements that pitch aspirin to prevent heart attacks would have you believe that low dosages of the 20th Century wonder drug are as sweetly benign as drinking water from a high mountain stream. (hsionline.com)