MEN2aTumorsMedullary thyroiSyndromesHyperparathyroidismGeneticMutationsMEN2BGlandsFMTCProto-oncogeneMEN2ThyroidectomyFamilialCancerPheochromocytomasGeneHypertensionTumorPrevalenceSyndrome typeOccurAutosomal dominant patternAffectsSurgeryPrognosisHormonesNodulesSymptomsTissuesDisorders that affectPatientsInvolvesFactorsMetabolismHereditary medullaryMucosalDiagnosisPancreas
MEN2a6
- The multiple endocrine neoplasia type 2A (MEN2A) is a monogenic disorder characterized by an autosomal dominant pattern of inheritance which is characterized by high risk of medullary thyroid carcinoma in all mutation carriers. (repositoriosalud.es)
- Having certain genetic conditions such as familial medullary thyroid cancer (FMTC), multiple endocrine neoplasia type 2A syndrome (MEN2A), or multiple endocrine neoplasia type 2B syndrome (MEN2B). (uofmhealth.org)
- CONCLUSION: The c.1998delinsTTCT variant in the RET gene is pathogenic and associated with a moderate risk for medullary thyroid carcinoma and rarely with other multiple endocrine neoplasia type 2A (MEN2A) manifestations. (bvsalud.org)
- Multiple endocrine neoplasia type 2 (MEN2) includes the following phenotypes: MEN2A, familial medullary thyroid carcinoma (FMTC, which may be a variant of MEN2A), and MEN2B. (nih.gov)
- MEN2A involves an increased risk for parathyroid adenoma or hyperplasia. (nih.gov)
- Type 2A (MEN2A): tumors or excessive growths form on at least two of the following three glands: thyroid, adrenal, or parathyroid. (endocrinology-centers.com)
Tumors17
- Multiple endocrine neoplasia type 2 (also known as "Pheochromocytoma (codons 630 and 634) and amyloid producing medullary thyroid carcinoma", "PTC syndrome," and "Sipple syndrome") is a group of medical disorders associated with tumors of the endocrine system. (wikipedia.org)
- Before gene testing was available, the type and location of tumors determined which type of MEN2 a person had. (wikipedia.org)
- Many different types of tumors are associated with multiple endocrine neoplasia. (medlineplus.gov)
- Hyperparathyroidism is the most common feature, followed by tumors of the pituitary gland, additional endocrine glands, and other organs. (medlineplus.gov)
- The loss of functional menin allows cells to divide too frequently, leading to the formation of tumors characteristic of multiple endocrine neoplasia type 1. (medlineplus.gov)
- It is unclear why these tumors preferentially affect endocrine tissues. (medlineplus.gov)
- This unchecked cell division can lead to the formation of tumors in endocrine glands and other tissues. (medlineplus.gov)
- Overview of Multiple Endocrine Neoplasias (MEN) The multiple endocrine neoplasia (MEN) syndromes comprise 4 genetically distinct familial diseases involving adenomatous hyperplasia and malignant tumors in several endocrine glands. (msdmanuals.com)
- RET proto-oncogene: a review and update of genotype-phenotype correlations in hereditary medullary thyroid cancer and associated endocrine tumors. (probl-endojournals.ru)
- 6. de Groot J.W., Links T.P., Plukker J.T., Lips C.J., Hofstra R.M. RET as a diagnostic and therapeutic target in sporadic and hereditary endocrine tumors. (probl-endojournals.ru)
- MEN 2A is a rare autosomal dominant disorder characterized by tumors of the C cells of the thyroid, adrenal medulla and parathyroid glands. (eurospe.org)
- Different types of benign (non-cancerous) growths and malignant (cancerous) tumors can develop in the thyroid gland. (medicareguide.com)
- Type 2B (MEN2B): formerly called multiple endocrine neoplasia type 3, this type can cause adrenal gland tumors, medullary thyroid cancer, and painful growths around nerves in your mucus membranes (neuromas). (endocrinology-centers.com)
- Familial medullary thyroid carcinoma (FMTC): patients with this condition have an 80% chance of developing medullary thyroid cancer, but less than a 5% chance of developing other endocrine tumors. (endocrinology-centers.com)
- The importance of identifying succinate dehydrogenase complex mutations is related to the risk for these patients of developing multiple tumors, including non-endocrine ones, showing an aggressive clinical presentation. (biomedcentral.com)
- Multiple endocrine neoplasia syndrome type 1 (MEN-1), loss-of-function germline mutations in the tumor suppressor gene MEN1 increase the risk of developing pituitary, parathyroid and pancreatic islet tumors, and less commonly thymic carcinoids, lipomas and benign adrenocortical tumors. (intechopen.com)
- In the case of multiple endocrine neoplasia type 2 (MEN 2), gain-of-function germline mutations clustered in specific codons of the RET proto-oncogene increase the risk of developing medullary thyroid carcinoma (MTC), phaeochromocytoma and parathyroid tumors. (intechopen.com)
Medullary thyroi4
- If the patient has it, other family members may also be tested to find out if they are at increased risk for medullary thyroid cancer. (uofmhealth.org)
- Having certain genetic conditions such as familial medullary thyroid cancer, multiple endocrine neoplasia type 2A syndrome, and multiple endocrine neoplasia type 2B syndrome can also increase the risk of thyroid cancer. (cdc.gov)
- A rare, genetic disorder that affects the endocrine glands and causes a type of thyroid cancer called medullary thyroid cancer, pheochromocytoma, and parathyroid gland cancer. (wustl.edu)
- Further laboratory and imaging studies revealed medullary thyroid cancer with multiple hepatic metastases and unilateral pheochromocytoma. (eurospe.org)
Syndromes12
- Multiple endocrine neoplasias are rare hereditary syndromes some of them with malignant potential. (nih.gov)
- citation needed] The table in the multiple endocrine neoplasia article lists the genes involved in the various MEN syndromes. (wikipedia.org)
- Calender A. Genetic testing in multiple endocrine neoplasia and related syndromes. (medscape.com)
- genetic diseases like multiple endocrine neoplasia type 2A and type 2B syndromes, or just having a history of thyroid cancer in the family, can increase the likelihood of developing it. (patientworthy.com)
- Phaeochromocytomas are also associated with a number of syndromes, including von Hippel-Lindau disease, Sturge-Weber syndrome, tuberous sclerosis, neurofibromatosis type 1, and Multiple Endocrine Neoplasia (MEN) type 2a and 2b. (endocrinesurgeon.co.uk)
- 2] Genetic syndromes can pre- dispose to bilateral PHEO, such as multiple endocrine neoplasia (MEN) 2A, MEN 2B, von Hippel-Lindau (VHL), neurofi- bromatosis type 1 (NF1), as well as mutations in the genes of myc-associated factor X (MAX), transmembrane protein 127 (TMEM127), and mutations in the subunits of the succinate dehydrogenase complex (SDHx). (scholarena.co)
- Inherited MTC occurs in association with multiple endocrine neoplasia (MEN) type 2A and 2B syndromes, but non-MEN familial MTC also occur. (medscape.com)
- In association with multiple endocrine neoplasia (MEN) syndromes, it is always bilateral and multicentric. (medscape.com)
- MTC typically is the first abnormality observed in both MEN 2A and 2B syndromes. (medscape.com)
- MTC associated with multiple endocrine neoplasia (MEN) syndromes may have a more aggressive course, which also depends on associated comorbidity (eg, pheochromocytoma ). (medscape.com)
- Approximately 25% of the cases are inherited as part of the multiple endocrine neoplasia type-2 (MEN-2) syndromes. (touchendocrinology.com)
- Herein we selected a Mendelian genetics form of familial cancer such as hereditary tumor syndromic endocrine neoplasias caused by highly penetrant germline mutations leading to pheochromocytoma-paraganglioma syndromes. (intechopen.com)
Hyperparathyroidism7
- MEN 2A is associated with medullary thyroid carcinoma (MTC), phaeochromocytoma, primary hyperparathyroidism, cutaneous lichen amyloidosis and Hirschprung's disease and MEN 2B with MTC, phaeochromocytoma, ganglioneuromatosis of the aerodigestive tract, musculoskeletal and ophthalmologic abnormalities. (nih.gov)
- The most common sign of multiple endocrine neoplasia type 1 is overactivity of the parathyroid glands (hyperparathyroidism). (medlineplus.gov)
- for example, hyperparathyroidism occurs only in type 2A, and medullary thyroid carcinoma is the only feature of FMTC. (medlineplus.gov)
- Multiple endocrine neoplasia, type 2A (MEN 2A) is an autosomal dominant syndrome characterized by medullary carcinoma of the thyroid, pheochromocytoma, parathyroid hyperplasia or adenomas (causing hyperparathyroidism), and occasionally cutaneous lichen amyloidosis. (msdmanuals.com)
- 15. Howe J.R., Norton J.A., Wells S.A.Jr. Prevalence of pheochromocytoma and hyperparathyroidism in multiple endocrine neoplasia type 2A: results of long-term follow-up. (probl-endojournals.ru)
- She presents regularly for evaluation, since she is in high risk of developing pheochromocytoma and hyperparathyroidism. (eurospe.org)
- Dr. Seib has clinical and research expertise in the surgical management of endocrine disorders in older adults, including primary hyperparathyroidism, thyroid cancer, and hyperthyroidism. (stanford.edu)
Genetic12
- These studies have successfully led to improved risk classification of prognosis in relation to the genotype, thus improving the management of the patients by thorough genetic counseling. (nih.gov)
- RiskScore analyzes over 100 genetic markers combined with the Tyrer-Cuzick model to estimate a woman's risk for developing breast cancer. (myriad.com)
- For a discussion of genetic heterogeneity of multiple endocrine neoplasia (MEN), see MEN1 (131100). (nih.gov)
- At the age of 5 years and 7 months the calcitonin levels after pentagastrin stimulation were found increased and a prophylactic total thyroidectomy was performed due to her genetic risk. (eurospe.org)
- Subjects with MEN 2A may exhibit a rapid progression and carriers of MEN 2A associated mutations need regular monitoring because of their genetic predisposition to tumor development. (eurospe.org)
- The phenotypic heterogeneity of sickle cell disease is likely the result of multiple genetic factors and their interaction with the sickle mutation. (biomedcentral.com)
- As family history, he has a sister operated for pheochromocytoma who had an adrenalectomy, a daughter operated for thyroid cancer who had a total thyroidectomy with lymph node curage, cervical radiotherapy sessions and a metastatic chemotherapy, and a son who had a bilateral adrenalectomy and whose genetic study showed a heterozygous C634R mutation on exon 11 of the RET gene (high risk category) [3]. (scholarena.co)
- prophylactic thyroidectomy can now be offered to specific types of patients with this genetic abnormality (see Prevention). (medscape.com)
- If you have a family member with MEN but do not have symptoms yourself, you should undergo a genetic test to determine your risk. (endocrinology-centers.com)
- As we waited for the results of the FNA, she did a genetic test for MEN 2A. (thyca.org)
- As we are in the era of evidence-based molecular diagnosis, predictive testing, genetic counseling, gene-informed cancer risk assessment, and preventative and personalized medicine, therefore, studying the Mendelian genetics of the familial forms of cancer is one approach that can set up the basis for gene-informed risk assessment and management for the patient and family. (intechopen.com)
- The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause. (lookformedical.com)
Mutations14
- Multiple endocrine neoplasia type 4 appears to have signs and symptoms similar to those of type 1, although it is caused by mutations in a different gene. (medlineplus.gov)
- Mutations in the MEN1 , RET , and CDKN1B genes can cause multiple endocrine neoplasia. (medlineplus.gov)
- Mutations in the MEN1 gene cause multiple endocrine neoplasia type 1. (medlineplus.gov)
- Mutations in the RET gene cause multiple endocrine neoplasia type 2. (medlineplus.gov)
- Germline RET Y791X mutations result in multiple endocrine neoplasia, type 2A (MEN 2A), which is associated with increased risk of developing thyroid medullary carcinoma (NCCN.org). (jax.org)
- Transcriptionally active fusions of ESR1 (ESR1-TAF) and somatic mutations in the estrogen receptor alpha (ERα) ligand-binding domain (LBD) cause endocrine therapy resistance in breast cancer. (bvsalud.org)
- MEN 2A and familial medullary thyroid carcinoma mutations result in activation of certain intracellular pathways. (msdmanuals.com)
- 5. Donis-Keller H., Dou S., Chi D., Carlson K.M., Toshima K., Lairmore T.C., Howe J.R., Moley J.F., Goodfellow P., Wells S.A.Jr. Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC. (probl-endojournals.ru)
- RiskScore is not calculated if the patient is known to carry a mutation in a breast cancer risk gene other that CHEK2 , or if there are any known mutations in high-penetrance breast cancer risk genes in the patient's family. (myriad.com)
- Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A. (rusmedserv.com)
- Mutations in the RET gene have been described in subjects with multiple endocrine neoplasia Type 2 (MEN 2A). (eurospe.org)
- Also called multiple endocrine adenomatosis or Wermer's syndrome, multiple endocrine neoplasia type 1 is the result of mutations of the MEN1 gene, causing tumor growth on the parathyroid gland, and then on the pancreas or pituitary gland. (endocrinology-centers.com)
- Caused by mutations to the RET (ret proto-oncogene) gene, there are three subtypes of multiple endocrine neoplasia type 2. (endocrinology-centers.com)
- p53 likely also plays a role given that p53 mutations are commonly found in advanced PC, and loss of wild-type protein function contributes to the phenotype of castration-resistant prostate cancer (CRPC). (oncotarget.com)
MEN2B1
- Multiple endocrine neoplasia type IIB (MEN2B) is an autosomal dominant hamartoneoplastic syndrome characterized by aggressive medullary thyroid carcinoma (MTC), pheochromocytoma, mucosal neuromas, and thickened corneal nerves. (nih.gov)
Glands10
- Multiple endocrine neoplasia is a group of disorders that affect the body's network of hormone-producing glands called the endocrine system. (medlineplus.gov)
- Management of the Parathyroid Glands During Preventive Thyroidectomy in Patients With Multiple Endocrine Neoplasia Type 2. (medscape.com)
- The affected endocrine glands may make high levels of hormones, which can lead to other medical problems such as high blood pressure and kidney stones. (wustl.edu)
- The different types of multiple endocrine neoplasia syndrome affect these different glands in different ways. (endocrinology-centers.com)
- Your body's endocrine system is a series of glands that release hormones that control important functions like growth and metabolism. (endocrinology-centers.com)
- Multiple endocrine neoplasia symptoms vary depending on the type and the glands that are affected. (endocrinology-centers.com)
- While there is no treatment for any type of multiple endocrine neoplasia, the affected endocrine glands can be treated individually with surgery, medication, or radiation therapy. (endocrinology-centers.com)
- The Endocrine System is a connected family of various glands, situated in different parts of the body that secrete hormones directly into the bloodstream instead of employing a duct-based system. (asterhospitals.ae)
- The endocrine system is a cluster of glands that secrete hormones. (asterhospitals.ae)
- Dr. Seib also completed a fellowship in Endocrine Surgery at UCSF, during which she cared for patients with complex disorders of the thyroid, parathyroid, and adrenal glands. (stanford.edu)
FMTC2
- Multiple endocrine neoplasia type 2 is divided into three subtypes: type 2A, type 2B (formerly called type 3), and familial medullary thyroid carcinoma (FMTC). (medlineplus.gov)
- Among the subtypes of type 2, type 2A is the most common form, followed by FMTC. (medlineplus.gov)
Proto-oncogene1
MEN24
- MEN2 is a sub-type of MEN (multiple endocrine neoplasia) and itself has sub-types, as discussed below. (wikipedia.org)
- MEN2 can present with a sign or symptom related to a tumor or, in the case of multiple endocrine neoplasia type 2b, with characteristic musculoskeletal and/or lip and/or gastrointestinal findings. (wikipedia.org)
- As noted, all types of MEN2 include pheochromocytoma and medullary thyroid carcinoma. (wikipedia.org)
- citation needed] The common feature among the three sub-types of MEN2 is a high propensity to develop medullary thyroid carcinoma. (wikipedia.org)
Thyroidectomy1
- Postoperative Complications After Prophylactic Thyroidectomy for Very Young Patients With Multiple Endocrine Neoplasia Type 2: Retrospective Cohort Analysis. (medscape.com)
Familial1
- Familial medullary thyroid carcinoma is a distinct variant of MEN 2A. (msdmanuals.com)
Cancer24
- The most common sign of multiple endocrine neoplasia type 2 is a form of thyroid cancer called medullary thyroid carcinoma. (medlineplus.gov)
- There are different types of thyroid cancer. (uofmhealth.org)
- Age, gender, and being exposed to radiation can affect the risk of thyroid cancer. (uofmhealth.org)
- A recent meta-analysis of 800 studies found evidence that eating 50 grams of processed meat every day increased the risk of colorectal cancer by 18 percent. (thyroidproadvice.com)
- Papillary is the most common type of thyroid cancer. (cdc.gov)
- Other types of thyroid cancer can usually be cured. (cdc.gov)
- Being exposed to radiation to the head and neck as a child increases the risk of thyroid cancer. (cdc.gov)
- What are the types of thyroid cancer? (patientworthy.com)
- Different types of cancer develop from the different kinds of cells in the thyroid. (patientworthy.com)
- Head and neck exposure to radiation can especially increase the risk of thyroid cancer in children. (patientworthy.com)
- Medullary Thyroid Carcinoma There are 4 general types of thyroid cancer. (msdmanuals.com)
- 13. Wygoda Z., Oczko-Wojciechowska M., GubaŁa E., Pawlaczek A., Kula D., Wiench M., WŁoch J. Medullary thyroid carcinoma: the comparison of the hereditary and sporadic types of cancer. (probl-endojournals.ru)
- In addition to the genes listed above, Myriad Genetics MyRisk ® Hereditary Cancer Test includes RiskScore ® , a precision medicine tool that predicts a woman's five year and lifetime risk for developing breast cancer. (myriad.com)
- To learn more about RiskScore and the medical management guidelines provided for patients identified to have a remaining lifetime risk of breast cancer >20%, you may view the result insert by clicking the link below. (myriad.com)
- Endocrine-Related Cancer. (ku.dk)
- Researchers at Washington University School of Medicine in St. Louis are leading a national study aimed at identifying patients with early-stage lung cancer who are at high risk of having the cancer return, even after. (wustl.edu)
- Relatives of BRCA1 and BRCA2 mutation carriers have long been proposed by epidemiological studies to have an increased risk of developing prostate cancer. (biomedcentral.com)
- Ultrasonography is also done, to determine how large the nodule is, whether it is solid or filled with fluid, whether other nodules are present, and whether it has high-risk characteristics for cancer. (merckmanuals.com)
- Papillary thyroid cancer is the most common type, accounting for 80 to 90% of all thyroid cancers. (merckmanuals.com)
- People who have received radiation treatment to the neck, usually for a noncancerous condition in infancy or childhood or for some other cancer in adulthood, are at greater risk of developing papillary cancer. (merckmanuals.com)
- Thyroid cancer is the most common endocrine malignancy. (touchendocrinology.com)
- 6,10,11 These fundamental biologic mechanisms have all been exploited in the diagnosis and treatment of thyroid cancer 12 and theoretically offer promise for the treatment of breast and other types of cancer. (touchendocrinology.com)
- The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening and diagnostic services. (mdanderson.org)
- The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
Pheochromocytomas1
- The most common is MEN-2A characterized by bilateral MTCs and pheochromocytomas, causing potentially deadly attacks of hypertension and tachyarrhythmias that are often more lethal than the MTC. (touchendocrinology.com)
Gene2
Hypertension3
- Symptoms in type 2 multiple endocrine neoplasia (MEN 2) can include hypertension, episodic sweating, diarrhea, pruritic skin lesions, or compressive symptoms from a neck mass. (medscape.com)
- Hypertension in MEN 2A patients with pheochromocytoma is more often paroxysmal than sustained, in contrast to the usual sporadic case. (msdmanuals.com)
- Of these, sodium-glucose co-transporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) agonists represent novel pharmacological agents that are included in the pharmacotherapy of patients with preserved or reduced systolic left ventricular function in heart failure, arterial hypertension, as well as in patients who are at increased risk of cardiovascular events. (escardio.org)
Tumor1
- In cell culture systems, the luminal ERα + tumor cells are either outcompeted by other types of cells or the cells rapidly downmodulate ERα expression 5 . (nature.com)
Prevalence2
- The prevalence of multiple endocrine neoplasia type 4 is unknown, although the condition appears to be rare. (medlineplus.gov)
- Despite the prevalence of type 2 DM, there are few effective long-term treatments for the patients. (escardio.org)
Syndrome type1
- Multiple endocrine neoplasia syndrome type 2: the value of screening and central registration. (probl-endojournals.ru)
Occur2
- They generally occur in endocrine organs (e.g. thyroid, parathyroid, and adrenals), but may also occur in endocrine tissues of organs not classically thought of as endocrine. (wikipedia.org)
- The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. (lookformedical.com)
Autosomal dominant pattern1
- citation needed] When inherited, multiple endocrine neoplasia type 2 is transmitted in an autosomal dominant pattern, which means affected people have one affected parent, and possibly affected siblings and children. (wikipedia.org)
Affects2
- Less often, NP affects people with multiple endocrine neoplasia type 2A (MEN 2A). (healthline.com)
- multiple endocrine neoplasia type 2 affects an estimated 1 in 35,000 people. (medlineplus.gov)
Surgery1
- In univariate and multivariate logistic regression analyses, age at initial surgery and risk classification were significant risk factors for stage III/IV hereditary MTC at initial diagnosis. (blogspot.com)
Prognosis1
- Based on the initial treatment, we identified the risk factors for poor prognosis by univariate and multivariate logistic regression. (blogspot.com)
Hormones2
- These types are distinguished by the genes involved, the types of hormones made, and the characteristic signs and symptoms. (medlineplus.gov)
- Endocrinology is a branch of healthcare science that deals with the disorders and functioning of the endocrine system, and its secretions are known as hormones. (asterhospitals.ae)
Nodules1
- [ 15 ] Ultrasound (US) features are used to categorize risk of malignancy and classify nodules as low risk (US1), intermediate risk (US2), or high risk (US3). (medscape.com)
Symptoms1
- The signs and symptoms of multiple endocrine neoplasia type 2 are relatively consistent within any one family. (medlineplus.gov)
Tissues1
- DM develops due to either a lack of insulin production (type 1 DM), as a result of destroyed beta cells of pancreas due to an autoimmune reaction, or resistance to insulin (type 2 DM), where insulin is being produced at least in the early stages of disease because beta cells are still present, but tissues do not respond to insulin [1]. (escardio.org)
Disorders that affect1
- It may be multiple endocrine neoplasia (MEN), a group of hereditary disorders that affect the endocrine system. (endocrinology-centers.com)
Patients8
- Cutaneous lichen amyloidosis in MEN 2A patients manifests as multiple pruritic, hyperpigmented, lichenoid papules in the scapular area of the back. (medscape.com)
- CIENCIASMEDICASNEWS: Is new American Thyroid Association risk classification for hereditary medullary thyroid carcinoma applicable to Chinese patients? (blogspot.com)
- Be confident you are testing for the primary clinically significant genes associated with your patients' risk. (myriad.com)
- Diabetic patients are at an increased risk of cardiovascular events and cardiovascular mortality. (escardio.org)
- In the clinical trials conducted thus far, the use of SGLT2 inhibitors was shown to improve the quality of life of patients with type 2 DM, have benefit in treatment of HF, either with reduced or preserved ejection fraction of the left ventricle. (escardio.org)
- Listeria monocytogenes is a foodborne pathogen that can cause serious invasive illness, mainly in certain well-defined high-risk groups, including elderly and immunocompromised patients, pregnant women, newborns and infants. (ijpmonline.org)
- The Endocrinology department at Aster Hospitals provides a full range of services for adult and pediatric patients with endocrine, metabolic diseases and Diabetes. (asterhospitals.ae)
- When considering surgical treatment, individualizing risk assessment is particularly important, as older patients can present with very different health profiles. (stanford.edu)
Involves2
- One risk factor involves exposure to high radiation levels, including radiation treatments to the head and/or neck, as well as professions that involve exposure. (patientworthy.com)
- Endocrinology also involves the study of the diseases of the endocrine system. (asterhospitals.ae)
Factors2
- Current evidence demonstrates that positive family history and several alterations in lipid metabolism are all important risk factors for coronary artery disease (CAD). (biomedcentral.com)
- HELLP syndrome, risk factors in first and second pregnancy: a population-based cohort study. (uib.no)
Metabolism1
- Journal of Clinical Endocrine & Metabolism 102(8):3591-3599, 2017. (mdanderson.org)
Hereditary medullary1
- The American Thyroid Association (ATA) proposed a new risk classification for hereditary medullary thyroid carcinoma (MTC) in 2015. (blogspot.com)
Mucosal1
- Multiple Endocrine Neoplasia, Type 2B (MEN 2B) Multiple endocrine neoplasia, type 2B (MEN 2B) is an autosomal dominant syndrome characterized by medullary thyroid carcinoma, pheochromocytoma, multiple mucosal neuromas and intestinal ganglioneuromas. (msdmanuals.com)
Diagnosis1
- Non-invasive prenatal diagnosis of multiple endocrine neoplasia type 2A using COLD-PCR combined with HRM genotyping analysis from maternal serum. (repositoriosalud.es)
Pancreas1
- b) latent autoimmune diabetes of adults (LADA), usually occurring in men over 40 years of age, in whom a progressive autoimmune process destroys the beta cells of pancreas, which is similar to type 1 DM. (escardio.org)