Proline-rich 12 (PRR12) is a protein of unknown function encoded by the gene PRR12. (wikipedia.org)
These proteins have regions rich in amino acids that are "poor protectors" of hydrogen bonds along the backbone of the protein, inhibiting the ability of these proteins to fold properly and allowing the possibility of protein aggregation. (wikipedia.org)
These regions may give this protein interesting secondary structure as a cluster of proline can form a polyproline helix. (wikipedia.org)
The glutamine and serine-rich protein 1 (QSER1) is the only closely related paralog to PRR12 (NCBI accession: EAW68214). (wikipedia.org)
Description: A sandwich quantitative ELISA assay kit for detection of Human Basic Salivary Proline Rich Protein 1 (PRB1) in samples from saliva or other biological fluids. (glideruniversity.org)
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Basic Salivary Proline Rich Protein 1 (PRB1) in saliva and other biological fluids. (glideruniversity.org)
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Basic Salivary Proline Rich Protein 1 (PRB1) in samples from saliva and other biological fluids with no significant corss-reactivity with analogues from other species. (glideruniversity.org)
Description: A sandwich ELISA kit for detection of Basic Salivary Proline Rich Protein 1 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (glideruniversity.org)
Expression of Recombinant EARLI1, a Hybrid Proline-rich Protein of Ara" by Lan Li, Chen Zhang et al. (marquette.edu)
N- and O-linked glycosylation site profiling of the human basic salivary proline-rich protein 3M. (unicatt.it)
In the present study, we show that the heterogeneous mixture of glycoforms of the basic salivary proline-rich protein 3M, encoded by PRB3-M locus, is a major component of the acidic soluble fraction of human whole saliva in the first years of life. (unicatt.it)
Remarkably, the minimal Bag6 complex defined here facilitates tail-anchored substrate transfer from small glutamine-rich tetratricopeptide repeat-containing protein α to TRC40. (rcsb.org)
Cryopyrin (also called NALP3, PYPAF1, or NACHT, leucine-rich repeat [LRR], and PYD domains-containing protein 3) is a member of the APAF-1/NOD1-like protein family, which regulates apoptosis and inflammation. (medscape.com)
Furthermore, pyrin interacts with proline-serine-threonine phosphatase-interacting protein (PSTPIP1), also known as CD2-binding protein 1 (CD2BP1), which is a tyrosine-phosphorylated protein involved in cytoskeletal organization and thereby involved in immunologic cellular interactions. (medscape.com)
Tyrosine2
Proline-rich tyrosine kinase 2 regulates spreading and migration of eosinophils after beta2-integrin adhesion. (uchicago.edu)
N. Boutahar, A. Guignandon, L. Vico, M. H. Lafage-ProustMechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activationIn J Biol Chem, volume 279, 2004. (fau.de)
Proteins6
Proline rich Gla, PRRG2, has a Gla domain which binds hyaluronan and is associated with proteins present in the extracellular matrix involved with cell adhesion and cell migration. (wikipedia.org)
Adults with no caries neutralize these acids better than adults with severe caries, and their parotid saliva possesses longer, less fragmented basic proline rich proteins, BPRPs (Ayad et al. (umich.edu)
Due to the presence of histatins (proline-rich proteins including cystatins and statherin), calcium and phosphate are maintained in supersaturation and are available for remineralization of tooth structure. (dentistrytoday.com)
This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. (cancerindex.org)
Our results demonstrate that SH3 (Src homology 3) domain-PRM (proline-rich motif) interactions involving multivalent linker proteins play central roles in concentrating NPFs at endocytic sites. (elifesciences.org)
For example, a region of WASP known as the proline-rich domain can bind to proteins that contain an "SH3" domain. (elifesciences.org)
Antimicrobial peptide2
This work shows for the first time the importance of proline isomers in the activity of an antimicrobial peptide. (nofima.no)
PepSAVI-MS Reveals a Proline-rich Antimicrobial Peptide in Amaranthus tricolor . (bvsalud.org)
Homology1
One study on the Epstein-Barr virus found close homology between a proline rich region in PRR12 and a 65 amino acid long region at the terminal end of EBNA-2 (a nuclear antigen of the virus). (wikipedia.org)
Encodes1
This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. (cancerindex.org)
Aliases1
Known aliases for PRR12 include "proline rich 12" and KIAA1205. (wikipedia.org)
Domain2
Tau phosphorylation manages your discussion among BIN1's SH3 domain and Tau's proline-rich site. (ap26113inhibitor.com)
In a Japanese patient with factor X deficiency, molecular analysis revealed a homozygous glutamine-to-glycine mutation at residue 32, which normally undergoes gamma-carboxylation within the gamma-carboxyglutamic acid-rich domain. (medscape.com)
Color rich pro line2
With an optimized precision tip, our special formula color rich pro line ensures easy application for any occasion, anytime. (skincarable.com)
You'll see how this color rich pro line completes and enhances your eye makeup in an instant. (skincarable.com)
Family1
The proline rich inositol polyphosphate 5-phosphatase (PIPP) is a relatively uncharacterised member of the 5-phosphatase family which hydrolyses PtdIns(3,4,5)P3 in vivo to negatively regulate Akt signalling in the neuronal-like PC12 cell line (Ooms et al. (monash.edu)
Activation1
Treatment of the synthetic peptide when it was bound to the exchange column with peptidylproline cis-trans-isomerase increased the amount of active peptide, indicating that isomerization of the proline peptide bond(s)was necessary for activation of the synthetic peptide. (nofima.no)