• Proteins/genes with a putative catabolic role and bacterium adaptation mechanisms during OPP degradation were identified via genomic and proteomic analysis. (nature.com)
  • A flavin-dependent monoxygenase (OppA1), one of the most up-regulated proteins in the OPP-growing cells, was isolated via heterologous expression and its catabolic activity was verified in vitro . (nature.com)
  • The obvious next step is to integrate this information and learn how genes, proteins, and/or epigenetic factors influence the phenotype of a disease in context of the system. (rsc.org)
  • In addition to the host regulatory mechanisms response to disease, the microbiome can make changes to the expression of the host features such as their genes, proteins, and/or PTMs. (rsc.org)
  • Expression profiles were acquired using two-dimensional gel electrophoresis for 737 protein spots, in which 640 proteins were identified using mass spectrometry. (nih.gov)
  • 3) Proteins whose expression was affected mainly by the growth condition. (nih.gov)
  • This group contains SSU ribosomal protein S305 / sigma(54) modulation protein, and two short-chain reductase-dehydrogenase proteins. (nih.gov)
  • More than half of all human genes are alternatively spliced, so it is expected that alternative pre- mRNA splicing will be responsible for the identification of more than 90 percent of all human proteins. (genomicglossaries.com)
  • rRNA genes contain regions of variable DNA sequence that are unique to the species carrying the … Ribosomal RNA is transcribed from ribosomal DNA (rDNA) and then bound to ribosomal proteins to form small and large ribosome subunits. (printerresource.com)
  • Translational regulation played an important role in the correct folding of heterologous proteins to form bioactive conformations during biogenesis. (biomedcentral.com)
  • Decelerating translation elongation speed has been shown to improve the soluble protein yield when expressing heterologous proteins in industrial expression hosts. (biomedcentral.com)
  • A potential expression platform for efficient pharmaceutical proteins and industrial enzymes production was provided without synonymous mutation. (biomedcentral.com)
  • Unlike the bacterial expression systems, which lack the modification enzymes, Pichia pastoris is able to produce heterologous proteins with post-translational modifications, especially glycosylation, which is crucial for optimal properties of many pharmaceutical proteins. (biomedcentral.com)
  • Since RNA-binding proteins (RBPs) are key players in the post-transcriptional regulation of gene expression precise knowledge of their binding sites is critical for determining their molecular function and for understanding their roles in cell development and disease. (biosyn.com)
  • For example, aph promoter combined with different RBS sequences were used for expression of reporter proteins in C. glutamicum (Zhang et al. (springeropen.com)
  • Anderson B.J. , Bills M.M. , Egerton J.R. , Mattick J.S. Cloning and expression in E coli of the gene encoding the structural subunit of Bacteroides nodosus fimbriae. (microbiologyresearch.org)
  • This is due to the delay of 60S subunit assembly by deleting non-essential ribosomal protein genes or 60S subunit processing factors, thus globally decreased the translation elongation speed and improved the co-translational folding, without perturbing the relative transcription level and translation initiation. (biomedcentral.com)
  • Our analysis showed that mRNA abundances, gene organization (operon) and gene essentiality are correlated in Buchnera (i.e., the most expressed genes are essential genes organized in operons) whereas no link between mRNA abundances and gene strand bias was found. (biomedcentral.com)
  • Because alternative RNA splicing allows different types of mRNA molecules to be created from a single gene, it generates the diversity of protein function and structure that is essential to complex organisms. (genomicglossaries.com)
  • High- fidelity mRNA amplification for gene profiling. (genomicglossaries.com)
  • Highly specific and effective gene silencing of any disease can be achieved by an accurate knowledge of the target mRNA sequence and rational design of its complementary antisense agents for the downregulation of its protein message. (genomicglossaries.com)
  • The most widely understood role of RNA is in protein synthesis, which includes messenger RNA (mRNA), transfer RNA (tRNA) and ribosomal RNA (rRNA) (see Chapter 2). (printerresource.com)
  • Some sRNAs positively regulate a gene by binding to a folded mRNA and revealing the RBS. (igem.org)
  • sRNAs are very short transcripts of RNA (usually ~100 base pairs in E. coli ) that are used in bacteria to positively or negatively regulate genes at the translational level by binding to the mRNA of the gene and either occluding the ribosomal binding site (RBS) and preventing ribosome binding or recruiting nucleases to degrade the mRNA. (igem.org)
  • Instead, the proportionality among expression level and growth price follows from bacterial development laws (16), and can be understood as a generic consequence of your up-regulation of ribosome synthesis upon translational inhibition, at the expense of your expression of non-ribosomal genes (fig. S9). (translateinthetownships.com)
  • Our work expands the functions of the Sm-like protein Hfq beyond its function in small RNA-mediated regulation and unveils a novel role of Hfq as crucial in ribosome biogenesis and translation. (ox.ac.uk)
  • 22, 1637-1639 (1994) REFERENCE 10 AUTHORS Janosi,L., Shimizu,I. and Kaji,A. TITLE Ribosome recycling factor (ribosome releasing factor) is essential for bacterial growth JOURNAL Proc. (nig.ac.jp)
  • Diversity and Similarity of Termination and Ribosome Rescue in Bacterial, Mitochondrial, and Cytoplasmic Translation. (umassmed.edu)
  • Ribosome profiling in mouse hippocampus: plasticity-induced regulation and bidirectional control by TSC2 and FMRP. (umassmed.edu)
  • Transcription analysis of all putative catabolic genes established their role in the metabolism of OPP. (nature.com)
  • Boros I. , Csordés-Tôth E. , Kiss A. , Tôrôk I. , Udvardy K. , Venetianer P. Identification of two new promoters probably involved in the transcription of a ribosomal RNA gene of Escherichia coli. (microbiologyresearch.org)
  • Moreover, transcriptomic analyses have demonstrated that, in free-living bacteria, gene transcription levels and chromosomal organization are mutually influenced. (biomedcentral.com)
  • The asymmetry of the distribution of the genes between the two strands of DNA is explained as being a means of minimizing interruptions in gene transcription due to collisions between the DNA and RNA polymerases. (biomedcentral.com)
  • Gene organization in the bacterial chromosome has very well known effects on transcription and a standard example is the organization of genes into operons, which allows for a sophisticated regulation of gene expression [ 9 ]. (biomedcentral.com)
  • The characterization of RNA and RNA interactions is closely related to transcription, for example, gene expression levels are investigated within a biological context. (biosyn.com)
  • The expression level of a protein is determined by transcription, translation and degradation rates, among them the beginning of transcription and translation are usually the rate-limiting steps. (springeropen.com)
  • The initiation of transcription is fundamentally controlled by the promoter elements, while the initiation of translation is mainly affected by the strength of ribosomal binding site (RBS). (springeropen.com)
  • 2) sequence segment located between the promoter and the first structural gene that causes partial termination of transcription. (insdc.org)
  • Recently, synthetic biologists have been focusing on creating logic gates in bacteria by controlling gene expression at various levels: transcription, translation, and post-translational processes. (igem.org)
  • This study also identified 43 growth-impairing inserts carrying multiple loci targeting 105 genes, of which 25 have homologs reported as essential in other bacteria. (biomedcentral.com)
  • Genomic studies on bacteria have clearly shown the existence of chromosomal organization as regards, for example, to gene localization, order and orientation. (biomedcentral.com)
  • This is a perfect illustration of the mutual influence between gene expression levels and chromosomal organization in bacteria. (biomedcentral.com)
  • Analyzing bacteria in late exponential phase, we capture ~40% ( E. faecalis ) and 43% ( E. faecium ) of the annotated protein-coding genes, determine 5′ and 3′ UTR (untranslated region) length, and detect instances of leaderless mRNAs. (frontiersin.org)
  • They used a gene that encodes for 16S ribosomal RNA (rRNA) in bacteria to characterize the nucleotide sequence of the bacillus from a patient with Whipple disease. (medscape.com)
  • Distel, D. L., DeLong, E. F., and Waterbury, J. Epub … Bacterial Identification by 16S rRNA Gene Sequence Analysis Background All bacteria contain 16S ribosomal RNA (rRNA) genes of approximately 1500 base pairs (bp) in length. (printerresource.com)
  • 6. I want to study ribosomal RNA expression and potential processing sites in bacteria. (printerresource.com)
  • A., 1992, The use of 16S ribosomal RNA targeted oligonucleotide probes to study competition between ruminai fibrolytic bacteria. (printerresource.com)
  • Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria. (lookformedical.com)
  • Simple logic gates, such as AND, OR, NAND, and NOR gates, have been successfully created in bacteria, but more complex logic circuits are still waiting to be designed and implemented into bacterial species. (igem.org)
  • These elements included a single promoter, which was mapped upstream of the 16S rRNA gene and which was similar to Escherichia coli consensus promoter sequences, an AT-rich upstream region, a GC-rich motif that may be involved in stringent control, leader and spacer antitermination sequences, sites for ribonuclease processing, and a putative factor-independent terminator sequence. (microbiologyresearch.org)
  • Brosius J. , Dull D.J. , Sleeter D.D. , Noller H.F. Gene organization and primary structure of a ribosomal RNA operon from Escherichia coli. (microbiologyresearch.org)
  • This bias is even more important when the essentiality of genes is taken into account, and essential genes distribution bias reaches 76% and 94% in Escherichia coli and Bacillus subtilis respectively [ 4 ]. (biomedcentral.com)
  • Whole-genome transposon-mutagenesis (TM) followed by identification of insertion sites is one of the most practical and frequently used experimental approaches to screen for essential bacterial genes [ 6 - 8 ]. (biomedcentral.com)
  • BIGSdb: Scalable analysis of bacterial genome variation at the population level. (cdc.gov)
  • The effect of Buchnera genome evolution on gene expression levels has also been analysed in order to assess the constraints imposed by the obligate symbiosis with aphids, underlining the importance of some gene sets for the survival of the two partners. (biomedcentral.com)
  • Two other major roles for noncoding RNA are in genome defense and in genetic regulation. (printerresource.com)
  • A. Ribosomal RNA analysis StructRNAfinder - predicts and annotates RNA families in transcript or genome sequences. (printerresource.com)
  • This study characterizes the variations in gene content, genome size, rearrangement rate, and the impact of domestication in Rosaceae mitogenomes and provides insights into their structural variation patterns and phylogenetic relationships. (biomedcentral.com)
  • The second ben/cat operon was located in a 92-kb scaffold along with (i) an operon ( opp ) comprising genes for the transformation of OPP to BA and 2-hydroxypenta-2,4-dienoate (and genes for its transformation) and (ii) an incomplete biphenyl catabolic operon ( bph ). (nature.com)
  • Berg K.L. , Squires C. , Squires C.L. Ribosomal RNA operon anti-termination Function of leader and spacer region box B-box A sequences and their conservation in diverse microorganisms. (microbiologyresearch.org)
  • It has also been shown that neighbouring genes in a bacterial chromosome tend to be co-expressed, even if they are not in the same operon [ 10 ], suggesting the existence of a "supra-operonic" organization [ 11 ]. (biomedcentral.com)
  • Indeed, bacterial genomes carry, on average, from 78% (for genomes containing the polymerase PolC) to 58% (for the other genomes) of their genes on the leading strand [ 3 ]. (biomedcentral.com)
  • G3: Genes, Genomes, Genetics. (wustl.edu)
  • Moreover, genetic and simple obesity share similar structural and functional features of dysbiosis, such as higher production of toxins with known potential to induce metabolic deteriorations (e.g. trimethylamine-N-oxide and indoxyl sulphate), higher abundance of genomes containing genes coding enzymes involved in the production of these toxic co-metabolites and higher abundance of pathways for biosynthesis of bacterial antigens (such as endotoxin) [13-15]. (deepdyve.com)
  • The antimicrobial wasp Polybia-MP1 peptide selectively kills bacterial cells! (biosyn.com)
  • Sequence and primer extension analysis revealed the presence of putative genes encoding tRNA lle and tRNA Ala within the 16S-23S spacer region, as well as a number of potential regulatory features. (microbiologyresearch.org)
  • Base modifications occur primarily in tRNA and ribosomal RNA (rRNA), and occur after the RNA is transcribed. (printerresource.com)
  • Specific tertiary structure types are observed for transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), certain introns, and ribozymes. (biosyn.com)
  • This interplay of bacterial effects on the pathogen can be beneficial to protect plants from infection, as shown with A . thaliana root experiments. (frontiersin.org)
  • Bartonella henselae is a fastidious, Gram-negative bacterial pathogen of cats and humans. (microbiologyresearch.org)
  • Borrelia burgdorferi , an emerging bacterial pathogen, is maintained in nature by transmission from one vertebrate host to another by ticks. (cdc.gov)
  • By means of DNA sequencing of a large sample collection of the pathogen from across the United States, we studied the gene for the bacterium's highly diverse OspC protein, protective immunity against which develops in animals. (cdc.gov)
  • The number of putative Regulators (genes that regulate it) and Targets (genes it regulates) for the given locus, based on experimental evidence. (yeastgenome.org)
  • and 16 were "novel" essential genes with no homologs reported to have an essential role in other bacterial species. (biomedcentral.com)
  • A better understanding of how these species cause disease and spread antibiotic resistance requires a knowledge of how its genes are controlled, on both the DNA and the RNA level. (frontiersin.org)
  • Comparison of partial citrate synthase gene ( gltA ) sequences for phylogenetic analysis of Bartonella species. (microbiologyresearch.org)
  • Colonization of the gut starts just after birth when pioneering species interact, through surface receptors, with gut cells to promote the expression of a specific set of host genes and favour the colonization of commensal microorganisms [6]. (deepdyve.com)
  • The downstream transformation of BA involved a meta -cleavage pathway, although its genetic organization and function was not revealed and the overall network of genes driving the full metabolic pathway of OPP is still not known. (nature.com)
  • Methods of molecular biology and genetic engineering to create structures that allow to express recombinant genes. (org.kz)
  • Interaction annotations are curated by BioGRID and include physical or genetic interactions observed between at least two genes. (yeastgenome.org)
  • According to [5] the results of biochemical tests used for bacterial identification and bio-typing may show variability due to the action of environmental factors on gene expression, the low discriminatory power of microorganisms with little genetic variability, and the risk of erroneous interpretations. (peertechzpublications.com)
  • Metabolic activity of the bacterial biofilm communities have altered as compared to the planktonic one such as increased rates of EPS production, activation or inhibition of particular genes associated with biofilm formation and decreased growth rate [ 39 ]. (biomedcentral.com)
  • A more detailed analyses on bacterial-fungal co-cultivation in narrow interaction channels of microfluidic devices revealed that the strongest inhibitory potential was found for Pseudomonas protegens CHA0, with its inhibitory potential depending on the presence of the GacS/GacA system controlling several bacterial metabolites. (frontiersin.org)
  • Mycologists have described the different fungal fruiting bodies, while geneticists have partly unravelled the regulation of sexual development. (exeter.ac.uk)
  • In previous studies, we isolated and sequenced for the first time the NOS gene from hemocytes of Panulirus argus, demonstrating the inducibility of this enzyme by lipopolysaccharide. (researchgate.net)
  • Outer-membrane protein variation is seen in association with phase variation, but lipopolysaccharide expression is preserved in piliated as well as extensively passaged non-piliated isolates. (microbiologyresearch.org)
  • Interestingly, the 2-MIB synthesis gene was consistently expressed, regardless of the water temperature. (mdpi.com)
  • Our goal was to develop a general and convenient strategy to improve heterologous protein synthesis in Pichia pastoris without mutating the expressed genes. (biomedcentral.com)
  • Finally, gadB2 and mutant gadB1 were co-expressed under the optimal promoter and RBS combination, thus converted Glu into GABA completely and improved GABA production to more than 25 g/L. This study provides useful promoters and RBS sequences for gene expression in C. glutamicum . (springeropen.com)
  • Therefore, optimization of promoters and RBS sequences has been applied for protein expression in C. glutamicum . (springeropen.com)
  • Triplicate egg samples were collected from each of three spawning tanks and analysis of 16S rRNA gene sequences revealed that 88.6% of reads could be identified to 186 taxonomic families. (omicsdi.org)
  • We aimed to identify novel essential genes in P. aeruginosa by shotgun antisense screening. (biomedcentral.com)
  • To also target low expressed essential genes, we included some variant steps that were expected to overcome the non-stringent regulation of the promoter carried by the expression vector used for the shotgun antisense libraries. (biomedcentral.com)
  • For the first time in P. aeruginosa , we applied regulated antisense RNA expression and showed the feasibility of this technology for the identification of novel essential genes. (biomedcentral.com)
  • The discovery of novel essential genes or pathways that have not yet been targeted by clinical antibiotics can underlie the development of alternative effective antibacterials to overcome existing mechanisms of resistance. (biomedcentral.com)
  • We decided not to use these lines because of our inability to determine whether a rat phenotype would be caused by the T-DNA disruption or a combination of the disruption and the effects of the AP3 gene. (purdue.edu)
  • Pilin expression is associated with auto-agglutination in liquid suspension or broth cultures, and appears to be necessary but not sufficient for expression of the agar-pitting phenotype and for the formation of biofilms. (microbiologyresearch.org)
  • Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. (yeastgenome.org)
  • Click "Phenotype Details" to view all phenotype annotations and evidence for this locus as well as phenotypes it shares with other genes. (yeastgenome.org)
  • This first comprehensive description of the ballan wrasse egg bacterial community is an initial step to understand the role and function of the microbiota on the phenotype of this fish. (omicsdi.org)
  • 6 identified a gene cluster, hbpCAD , encoding the upper metabolic pathway of OPP which involves the transformation of OPP to 2-hydroxypenta-2,4-dienoateand benzoic acid (BA). (nature.com)
  • Our results indicate that Hfq-mediated regulation of ribosomes is independent of its function as sRNA-regulator. (ox.ac.uk)
  • presents an opportunity to manipulate gene expression within the cells to treat various diseases, and acts as a powerful tool for studying gene function utilizing antisense agents to manage the diseases by regulating the expression of the specific factor that actually causes the particular disease. (genomicglossaries.com)
  • Therapeutic tiny or short modified antisense oligonucleotides (Tiny ASOs) can block gene expression or modulate splice-switching! (biosyn.com)
  • Antisense is the non-coding DNA strand of a gene. (genome.gov)
  • This organization of the chromosome can be described as being an adaptive and functional tool, essential for the survival of the bacterial cell. (biomedcentral.com)
  • Community-level differences in functional potential were driven by enrichment of genes associated with carbon and nitrogen fixation in non-disinfected systems and γ-aminobutyrate metabolism in disinfected systems likely associated with the recycling of amino acids. (biomedcentral.com)
  • Baylis H.A. , Bibb M.J. Transcriptional analysis of the 16S rRNA gene of the rrnD gene set of Streptomjces A3(2). (microbiologyresearch.org)
  • At Day 5, there was a consistent reduction in 16S rRNA gene sequence richness across the tanks. (omicsdi.org)
  • Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. (yeastgenome.org)
  • Past genomic studies have comprehensively described the organization of the bacterial chromosome, for example in terms of gene localization, order and orientation. (biomedcentral.com)
  • Lateral gene transfers resulted in different linkages between the ospC gene and loci of the chromosome or other plasmids. (cdc.gov)
  • We note that some drugresistance genes usually are not typically expressed constitutively, but demand induction by the target antibiotic (257). (translateinthetownships.com)
  • Moreover, it is well recognized that the excessive use of broad-spectrum antibiotics can affect the relative proportions of gut microbial populations and foster bacterial resistance [24]. (deepdyve.com)
  • We found that the distributions and frequencies of types of OspC genes differed between populations of B. burgdorferi in the Northeast, the Midwest, and California. (cdc.gov)
  • Targeting of novel essential pathways is expected to play an important role in the discovery of new antibacterial agents against bacterial pathogens, such as Pseudomonas aeruginosa , that are difficult to control because of their ability to develop resistance, often multiple, to all current classes of clinical antibiotics. (biomedcentral.com)
  • ResFinder ( 10 ) identified no additional acquired antimicrobial resistance genes which was consistent with antimicrobial susceptibility testing results (data not shown). (cdc.gov)
  • One of the few antigens against which mammals develop protective immunity is the highly polymorphic OspC protein, encoded by the ospC gene on the cp26 plasmid. (cdc.gov)
  • The Giardia lamblia vsp gene repertoire: characteristics, genomic organization, and evolution. (mbl.edu)
  • Using an oligonucleotide-based microarray, we normalized the transcriptomic data by genomic DNA signals in order to have access to inter-gene comparison data. (biomedcentral.com)
  • It can be accessed online at www.helmholtz-hiri.de/en/datasets/enterococcus through an instance of the genomic viewer JBrowse. (frontiersin.org)
  • Growth-rate dependent expression of constitutive (unregulated) genes-Figure 3C shows that, beneath translation-limited growth, the expression levels (i.e. protein concentration) of unregulated genes lower linearly with decreasing development rate (16, 42). (translateinthetownships.com)
  • Pichia pastoris is a widely used platform for heterologous protein expression, which is a "generally regarded as safe" (GRAS) microorganism. (biomedcentral.com)
  • These loci (rrnA, rrnB and rrnC) were isolated on recombinant lambda clones, and comprised 16S, 23S and 5S rRNA genes closely linked in that order. (microbiologyresearch.org)
  • Identification of acquired antimicrobial resistance genes. (cdc.gov)
  • 1. Identification and characterization of Arabidopsis rat mutants and molecular cloning of RAT genes (Gelvin, Citovsky, Hohn, and Ziemienowicz laboratories, with help from undergraduate students at Tuskegee University). (purdue.edu)
  • a regulatory region that controls epigenetic imprinting and affects the expression of target genes in an allele- or parent-of-origin-specific manner. (insdc.org)
  • In this review, we discuss considerations of the study design for each data feature, the limitations in gene and protein abundance and their rate of expression, the current data integration methods, and microbiome influences on gene and protein expression. (rsc.org)
  • a transcriptional cis regulatory region that when located between an enhancer and a gene's promoter prevents the enhancer from modulating the expression of the gene. (insdc.org)
  • To enhance GABA production in C. glutamicum , ribosomal binding site (RBS) sequence and promoter were searched and optimized for increasing the expression efficiency of gadB2 . (springeropen.com)
  • Click "Regulation Details" to view all regulation annotations, shared GO enrichment among regulation Targets, and a regulator/target diagram for the locus. (yeastgenome.org)
  • Using sRNAs in our bacterial decoder will help us achieve on/off behavior rather than intermediate levels of outputs, since sRNAs do little at low concentrations but demonstrate strong regulation at high concentrations. (igem.org)
  • There are many approaches being used to control infections by suppressing its formation but CRISPR-CAS (gene editing technique) and photo dynamic therapy (PDT) are proposed to be used as therapeutic approaches to subside bacterial biofim infections, especially caused by deadly drug resistant bad bugs. (biomedcentral.com)
  • Co-infections in leprosy may change the web host immunity either by improving inflammation and injury resulting in reactions and neuritis [7], or depressing body's defence mechanism leading to higher bacterial load or relapses [8]. (researchensemble.com)
  • Gene neighborhoods for capsule gene clusters of reference strain Neisseria meningitidis serogroup C FAM18 and urethral strains NM1 and NM2. (cdc.gov)
  • Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB. (cdc.gov)
  • This comprehensive global TSS mapping atlas provides a valuable resource for RNA biology and gene expression analysis in the Enterococci. (frontiersin.org)
  • Comparative analysis of six genera from the Amygdaloideae and five from the Rosoideae subfamilies of Rosaceae revealed that three protein-coding genes were absent from the mitogenomes of five Rosoideae genera. (biomedcentral.com)
  • Here, a large-scale deletion library of ribosomal protein (RP) genes was constructed for heterologous protein expression in Pichia pastoris , and 59% (16/27) RP deletants have significantly increased heterologous protein yield. (biomedcentral.com)
  • Combinatorial assembly of tac , cspB and sod promoters and lacZ , cspB and sod RBS elements conferred differential expression of two reporters, eGFP and mCherry in pTGR platform of C. glutamicum (Ravasi et al. (springeropen.com)
  • 4538 / GF4 "Development of biotechnology for the creation of genetically modified potato plants with increased resistance to abiotic stresses based on the optimization of the expression of mutated variants of the AteIF2α transgene", scientific supervisor - Dr. of Biological Sciences. (org.kz)
  • Over time, OspC genes were transferred between strains through recombinations involving the whole or parts of the gene and one or both flanks. (cdc.gov)
  • Phylogenetic affiliations of mesopelagic acantharia and acantharian-like environmental 18S rRNA genes off the southern California coast. (mbl.edu)
  • Gene synteny is observed within much of the capsule gene cluster, except that the cssA-C genes are missing in NM1 and NM2. (cdc.gov)
  • a DNA region that includes DNase hypersensitive sites located 5′ to a gene or gene cluster, and which confers high-level, position-independent, and copy number-dependent expression on that gene or gene cluster. (insdc.org)