• However, inosine pairs preferentially with cytidine (C) and its introduction to RNA, e.g. by the action of ADARs, thereby destabilizes double stranded RNA by changing AU base-pairs to IU mismatches (Bass and Weintraub, Cell, 1988). (wikidoc.org)
  • The molecule consists of hypoxanthine connected to a ribofuranose ring via a glycosidic bond. (acs.org)
  • Adenosine is a purine nucleoside composed of a molecule of adenine attached to a ribose sugar molecule ( ribofuranose ) moiety via a β-N 9 - glycosidic bond . (infogalactic.com)
  • Inosine is a natural purine nucleoside that commonly occurs in transfer RNAs in humans. (acs.org)
  • PMID- 214393 TI - Regulation of growth & metabolism of ovariectomised rat uterus by adenosine 3', 5'-cyclic monophosphate. (nih.gov)
  • Adenosine also plays a role in regulation of blood flow to various organs through vasodilation . (infogalactic.com)
  • PMID- 214392 TI - Regulation of lipogenesis by adenosine 3', 5'-cyclic monophosphate in chicken liver in vitro. (nih.gov)
  • Fast rhythms of the heart that are confined to the atria (e.g., atrial fibrillation , atrial flutter ) or ventricles (e.g., monomorphic ventricular tachycardia ) and do not involve the AV node as part of the re-entrant circuit are not typically converted by adenosine. (infogalactic.com)
  • In 2019, researchers found that a gene editor unexpectedly converted a small amount of adenosine in an RNA to inosine. (acs.org)
  • The researchers found that seawater temperature decreases induce the cephalopods to self-edit mRNA adenosine to inosine . (acs.org)