• vasodilation
  • Subsequently, it was suggested that EDHF is a sulfur signal that results in activation of K channels via sulfhydration of a cysteine residue (formation of a cysteine persulfide) (https://doi.org/10.1161/CIRCRESAHA.111.240242) C-type natriuretic peptide (CNP) has been shown to exert a variety of cardiovascular effects including vasodilation and hyperpolarization of arteries through the opening of KCa+-channels. (wikipedia.org)
  • dysfunction
  • Basing on erectile dysfunction causes, a man can be prescribed different drugs that increase potency . (landacorp.com)
  • The autonomic nervous system's physiological state (see below) leading to loss of consciousness may persist for several minutes, so If sufferers try to sit or stand when they wake up, they may pass out again The person may be nauseated, pale, and sweaty for several minutes or hours Reflex syncope occurs in response to a trigger due to dysfunction of the heart rate and blood pressure regulating mechanism. (wikipedia.org)
  • autonomic
  • Tolerance to the autonomic effects of increased blood pressure and heart rate, and increased urine output, develops with chronic use (i.e., these symptoms become less pronounced or do not occur following consistent use). (wikipedia.org)
  • pathophysiology
  • Given that the bioactive lipid sphingosine 1-phosphate is involved in cardiovascular pathophysiology, and since lipid accumulation and inflammation are hallmarks of calcific aortic stenosis, the role of sphingosine 1-phosphate on the pro-inflammatory/pro-osteogenic pathways in human interstitial cells from aortic and pulmonary valves was investigated. (jove.com)
  • First we will review some basic concepts about definitions and pathophysiology of IAH and then we will present a detailed analysis of IAH in the setting of AP. (intechopen.com)
  • decreases
  • Activity in this range is associated with the respiratory sinus arrhythmia (RSA), a vagally mediated modulation of heart rate such that it increases during inspiration and decreases during expiration. (wikipedia.org)
  • synthesis
  • In vitro studies have shown that paracrine dialogs between human adipocytes and inflammatory cells present in adipose tissue (ie, macrophage, lymphocytes, and others) promote an increased synthesis of numerous biomolecules, 4 leading to a low-grade inflammatory microenvironment. (ahajournals.org)
  • Aging
  • Exercise and physical activity are widely regarded as important interventions to increase longevity and promote healthy aging and well-being. (hindawi.com)
  • While all physiological systems appear responsive to the beneficial effects of exercise, further research is required to understand the relationship between free radical metabolism in cellular and molecular processes affected by exercise in the context of human aging. (hindawi.com)
  • This special issue contains both review and original research articles which, when combined together, provide an interesting insight into the current state of basic and applied research in free radical metabolism, exercise, and aging. (hindawi.com)
  • Thus
  • The low pKa of taurine's sulfonic acid group ensures this moiety is negatively charged in the pH ranges normally found in the intestinal tract, thus it improves the surfactant properties of the cholic acid conjugate. (wikipedia.org)
  • adaptation
  • Intermittent hypoxic training (IHT), also known as intermittent hypoxic therapy, is a non-invasive, drug-free technique aimed at improving human performance and well-being by way of adaptation to reduced oxygen. (wikipedia.org)
  • and -λογία, -logia), environmental physiology or physiological ecology is a biological discipline that studies the adaptation of an organism's physiology to environmental conditions. (wikipedia.org)
  • cardiac
  • Both conditions lead to a decrease in cardiac output which is accompanied by an elevation of central venous pressure that reflects, in an imperfect fashion, the real status of intravascular volume in this scenario [ 5 ].Stasis in deep venous circulation puts the patient in an increased risk for thromboemolism. (intechopen.com)
  • Heart failure characteristically involves increased catecholamine activity on the heart, which is responsible for a number of deleterious effects, including increased oxygen demand, propagation of inflammatory mediators, and abnormal cardiac tissue remodeling, all of which decrease the efficiency of cardiac contraction and contribute to the low ejection fraction. (wikipedia.org)
  • doses
  • Moderate doses of caffeine (around 5 mg/kg) can improve sprint performance, cycling and running time trial performance, endurance (i.e., it delays the onset of muscle fatigue and central fatigue), and cycling power output. (wikipedia.org)
  • membrane
  • Taurine crosses the blood-brain barrier and has been implicated in a wide array of physiological phenomena including inhibitory neurotransmission, long-term potentiation in the striatum/hippocampus, membrane stabilization,[unreliable medical source? (wikipedia.org)
  • effects
  • In conclusion, the impact of changes in GABAergic input is very difficult to predict in these settings, emphasizing the need for experiments performed in conscious animals when aiming at determining the cardiovascular effects of compounds acting on GABAergic neurons. (hindawi.com)
  • In addition to CNS effects GABAergic neurons also have a significant impact on the cardiovascular system. (hindawi.com)
  • A 2007 review of meditative practices that included Transcendental Meditation concluded that the definitive health effects of meditation cannot be determined as the scientific evidence was of poor quality, though the review has been criticized for using an inappropriate method for assessing quality. (wikipedia.org)
  • These protect them from the damaging effects of ice formation and falling rates of enzyme catalysis at low temperatures, and from enzyme denaturation and increased photorespiration at high temperatures. (wikipedia.org)
  • Targeted delivery is believed to improve efficacy while reducing side-effects. (wikipedia.org)
  • Increasing developments to novel treatments requires a controlled microenvironment that is accomplished only through the implementation of therapeutic agents whose side-effects can be avoided with targeted drug delivery. (wikipedia.org)
  • prevention
  • To date, trials that target major cardiovascular risk factors in the prevention of AD remain inconclusive but have become an important focus of international research as described by contributors of this special volume in their overviews. (iospress.nl)
  • The aim of this chapter is to review basic pathophysyology and clinical concepts about prevention, diagnosis and medical-surgical management of IAH in the setting of AP. (intechopen.com)
  • receptors
  • Subtypes of γ -aminobutyric acid(A) receptors: classification on the basis of subunit structure and receptor function," Pharmacological Reviews , vol. 50, no. 2, pp. 291-313, 1998. (hindawi.com)
  • exposure
  • Though practical constraints (cost and radiation exposure) limit the routine use of CT scan to estimate individual cardiovascular risk at the population level, this study contributes to the fascinating discussion regarding the potentially causal role of fat abundance around the heart in coronary atherosclerosis. (ahajournals.org)
  • stroke
  • For the treatment of primary hypertension, meta-analyses of studies which mostly used atenolol have shown although beta blockers are more effective than placebo in preventing stroke and total cardiovascular events, they are not as effective as diuretics, medications inhibiting the renin-angiotensin system (e.g. (wikipedia.org)
  • acute
  • However, cell damage produced by acute and unaccustomed exercise, as a result of an enhanced production of free radical species, is a recognised phenomenon. (hindawi.com)
  • IAH increases morbidity and mortality in acute pancreatitis (AP) and has become an issue of concern [ 2 ]. (intechopen.com)
  • blood
  • They block this enzyme and increase the blood supply to the penis. (landacorp.com)
  • Another review did find a reduction in diastolic and systolic blood pressure in those who practiced TM compared to controls. (wikipedia.org)
  • significantly
  • and (d) pHi and NHE protein expression/activity are significantly increased by LPS, in both a dose- and time- dependent manner, but NBCs protein expression is not. (jove.com)
  • systems
  • IAH is caused by persistent elevation in intra-abdominal pressure that is associated with multiple physiological derangements in almost all systems. (intechopen.com)
  • important
  • It is important to differentiate between physiological adaptations to mild hypoxia and re-oxygenation episodes (i.e., the IHT protocol) and frequent nocturnal suffocation awakenings produced by sleep apnea, which might result in various pathologies. (wikipedia.org)
  • However
  • However, a number of physiological and technical issues can affect the accuracy of the results and appropriate guidelines for the technique have been published. (jove.com)
  • however, physiological changes caused by cocaine withdrawal include vivid and unpleasant dreams, insomnia or hypersomnia, anger, increased appetite and psychomotor retardation or agitation. (wikipedia.org)
  • exercise
  • They review literature pertaining to antioxidants as well as prooxidants, in relation to oxidative damage, and they further discuss mediators of the inflammatory response to exercise. (hindawi.com)
  • time
  • The editor and reviewers' affiliations are the latest provided on their Loop research profiles and may not reflect their situation at the time of review. (frontiersin.org)
  • While life expectancy is increasing at an exponential rate, the length of time spent in good health across the lifespan (health-span) is in decline. (hindawi.com)
  • LPS also increases cellular growth, pHi and NHE in a dose- and time-dependent manner. (jove.com)
  • protein
  • Moreover, MEG3 was decreased in cisplatin-insensitive LAD tissues while p53 protein levels were decreased and Bcl-xl protein levels increased. (jove.com)