• retinitis
  • Long term leaders of the board included Hon. Richard Lane and Kenneth Barasch, M.D. First Lady Eleanor Roosevelt wrote about the NCCB in its first year of existence, drawing attention to the goal of raising $50,000 for eye clinics and treat retinitis pigmentosa (RP). (wikipedia.org)
  • deterioration
  • Although no effective treatment for RP has been identified, participants supplemented with a daily oral dose of 15,000 IU vitamin A palmitate have shown, on average, a slower rate of deterioration of retinal function when the intervention is continued over several years(4). (clinicaltrials.gov)
  • These progressions include the formation of cataracts, deterioration of the iris with adhesions forming between the iris and the lens or the cornea, and shallowing of the anterior chamber which may increase intraocular pressure, causing eye pain. (wikipedia.org)
  • optic
  • 2- Retinal state and retinal edema by Color Photography, Multifocal Electroretinography, and OCT (Optic Coherent Tomography). (clinicaltrials.gov)
  • Failure of the cells of the posterior portion of the optic vesicles to express growth hormone affects the differentiation of other cells of the eye. (wikipedia.org)
  • Mitohondrial optic neuropathies are a heterogenous group of disorders that present with visual disturbances resultant from mitochondrial dysfunction within the anatomy of the Retinal Ganglion Cells (RGC), optic nerve, optic chiasm, and optic tract. (wikipedia.org)
  • The generalized, common presentation for this broad and inclusive group of diseases is painless, bilateral loss of visual acuity and pallor of the optic disc accompanied with varying degrees of dyschromatopsia and central/cecocentral scatomas. (wikipedia.org)
  • leukocoria
  • Patients with Norrie disease may develop cataracts, leukocoria (a condition where the pupils appear white when light is shone on them), along with other developmental issues in the eye, such as shrinking of the globe and the wasting away of the iris. (wikipedia.org)
  • Abnormalities
  • The degree of these abnormalities varies between individual dogs, and even between the same dog's eyes. (wikipedia.org)
  • However, there have been a few rare cases where females have shown symptoms associated with Norrie disease such as retinal abnormalities and mild hearing loss. (wikipedia.org)
  • disorder
  • Although the etiology of Behcet's disease is unknown, evidence suggests that an interleukin-2 receptor bearing auto-aggressive cells may play an important role in this disorder. (clinicaltrials.gov)
  • gene
  • As a result, gene-based therapies are being pursued to treat eye genetic diseases that were once considered untreatable. (clinicaltrials.gov)
  • The U.S Food and Drug Administration in October 2017 revealed their plans to recommend gene therapy as a way to treat inherited retinal diseases. (eyepain.org)
  • Gene therapy can be used to treat these eye disorders. (eyepain.org)
  • Gene therapy can be used to treat these diseases by adding new genes to their cells to replace the missing or dysfunctional ones. (eyepain.org)
  • With the application of gene therapy, patients with different types of inherited retinal diseases can be able to regain their vision. (eyepain.org)
  • Clinical diagnosis is made by function tests of the eye and confirmed using a specific method called molecular testing to verify that the PDE6B gene is not correct. (clinicaltrials.gov)
  • The official name of the gene is "Norrie disease (pseudoglioma)", and its official symbol is NDP. (wikipedia.org)
  • Behcet's Disease
  • This study will evaluate the safety and effectiveness of Zenapax in controlling recurrent eye inflammations associated with Behcet's disease. (clinicaltrials.gov)
  • Behcet's disease is usually treated with corticosteroids to suppress inflammation. (clinicaltrials.gov)
  • Twenty patients who are 18 years of age or older with Behcet's disease will be randomly assigned to receive either Zenapax or placebo in addition to their standard immunosuppressive therapy. (clinicaltrials.gov)
  • The primary purpose of the study is to investigate the safety and efficacy of Zenapax in controlling the recurrent, explosive nature of ocular manifestations in patients with Behcet's disease. (clinicaltrials.gov)
  • The purpose of this study is to find if autologous stem cell transplantation can stop the progression of intractable eye lesions of Behcet's Disease or even to improve it. (clinicaltrials.gov)
  • To test in a pilot study the effect of autologous stem cell transplantation in stopping the progression of retinal damage of eye lesions in Behcet's Disease by repairing the vascular damage, and possibly to improve the lesions. (clinicaltrials.gov)
  • infectious diseases
  • loiasis ( B74.3+ ) onchocerciasis ( B73+ ) phthiriasis ( B85.3+ ) (H03.1*) Involvement of eyelid in other infectious diseases classified elsewhere Involvement of eyelid in: herpesviral (herpes simplex) infection ( B00.5+ ) leprosy ( A30. (wikipedia.org)
  • The Journal of Infectious Diseases. (wikipedia.org)
  • neurological disease
  • the Krembil is also one of the largest research institutes in Canada focusing on human neurological disease from both a basic science and clinical research perspective. (wikipedia.org)
  • disorders
  • Research within the Krembil is directed at the development of treatments for neurodegenerative diseases (Alzheimer's disease, Parkinson's disease), epilepsy, stroke, brain tumours, concussions, spinal cord injuries, neurophthalmologic and other ocular disorders, multiple sclerosis and autoimmune disorders. (wikipedia.org)
  • At the Krembil, neuroscientists explore the function of the nervous system as they develop treatments for neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, epilepsy, spinal cord injuries, cerebral ischemia (stroke), vascular brain malformations, aneurysms, brain tumours and pain disorders. (wikipedia.org)
  • eyelid
  • All treatments were performed by a single retinal specialist using topical proparacaine drops under sterile conditions (eyelid speculum and povidone-iodine). (clinicaltrials.gov)
  • H02.6) Xanthelasma of eyelid (H03.0*) Parasitic infestation of eyelid in diseases classified elsewhere Dermatitis of eyelid due to Demodex species ( B88.0+ ) Parasitic infestation of eyelid in: leishmaniasis ( B55. (wikipedia.org)
  • anatomy
  • Ophthalmology (/ˌɒfθælˈmɒlədʒi/ or /ˌɒpθælˈmɒlədʒi/) is the branch of medicine that deals with the anatomy, physiology and diseases of the eyeball and orbit. (wikipedia.org)
  • Ibn al-Haytham (Alhazen), an Arab scientist with Islamic beliefs, wrote extensively on optics and the anatomy of the eye in his Book of Optics (1021). (wikipedia.org)
  • Surgery
  • Ophthalmologists are allowed to medically treat eye disease, implement laser therapy, and perform incisional surgery when warranted. (wikipedia.org)
  • Condition
  • Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives. (diseaseinfosearch.org)
  • Usher
  • This study will explore clinical and genetic aspects of Usher syndrome, an inherited disease causing deafness or impaired hearing, visual problems, and, in some cases, unsteadiness or balance problems. (clinicaltrials.gov)
  • study
  • This study will collect blood and DNA samples from patients with inherited eye diseases to be used in research to identify genetic factors responsible for these conditions. (clinicaltrials.gov)
  • Medieval Islamic Arabic and Persian scientists (unlike their classical predecessors) considered it normal to combine theory and practice, including the crafting of precise instruments, and therefore found it natural to combine the study of the eye with the practical application of that knowledge. (wikipedia.org)
  • In the 17th and 18th centuries, hand lenses were used by Malpighi, and microscopes by van Leeuwenhoek, preparations for fixing the eye for study by Ruysch, and later the freezing of the eye by Petit. (wikipedia.org)
  • This allowed for detailed study of the eye and an advanced model. (wikipedia.org)
  • researchers
  • The stored samples will be made available to researchers along with information about the patient's disease, but without patient identifiers. (clinicaltrials.gov)
  • Although a modest foundation not exceeding $5 million in annual endowment, Fight for Sight had given out more than $20 million in grants to over 3,000 eye researchers by 2009. (wikipedia.org)