• reflects
  • Micronucleus (MN) formation in reticulocytes (RETs) reflects cytogenetic damage induced by clastogenic agents, such as ionizing radiation and alkylating agents, or by aneugenic agents, such as compounds that interfere with the mitotic spindle apparatus [ 1 - 3 ]. (pubmedcentralcanada.ca)
  • Ends
  • citation needed] The development begins with the extrusion of the normoblast nucleus and ends when the reticulocyte has lost its organelles. (wikipedia.org)
  • represents
  • At present, the need to use both fresh reticulocytes and fresh P. vivax isolates represents a major obstacle towards this goal, particularly for laboratories located in non-endemic countries. (technologynetworks.com)
  • This new technique allows the storage of HSC-derived reticulocytes which can be used for later invasion tests and represents an important step towards the establishment of a continuous P. vivax culture. (technologynetworks.com)
  • Method
  • 2. A method according to claim 1 wherein the harvesting step involves sequential sedimentation steps of Rouleaux bodies in which reticulocytes tend to sediment in a first sedimentation step, and tend to not sediment in a second sedimentation step. (google.es)
  • Here, we describe a new method for the cryopreservation of HSC-derived reticulocytes to be used for both P. falciparum and P. vivax invasion tests. (technologynetworks.com)