• BMAA
  • The non-protein amino acid beta-N-methylamino-L-alanine (BMAA) was first associated with the high incidence of Amyotrophic Lateral Sclerosis/Parkinsonism Dementia Complex (ALS/PDC) in Guam, and has been implicated as a potential environmental factor in ALS, Alzheimer's disease, and other neurodegenerative diseases. (mdpi.com)
  • Sacks and Paul Alan Cox subsequently wrote that a local species of flying fox, which is now extinct due to overhunting, had been feeding on cycads and concentrating β-methylamino-L-alanine (BMAA), a known neurotoxin, in its body fat. (wikipedia.org)
  • β-Methylamino-L-alanine, or BMAA, is a non-proteinogenic amino acid produced by cyanobacteria. (wikipedia.org)
  • BMAA is a derivative of the amino acid alanine with a methylamino group on the side chain. (wikipedia.org)
  • A study performed in 2015 with vervets (Chlorocebus sabaeus) in St. Kitts, which are homozygous for the apoE4 gene (a condition which in humans is a risk factor for Alzheimer's disease), found that vervets orally administered BMAA developed hallmark histopathology features of Alzheimer's Disease including amyloid beta plaques and neurofibrillary tangle accumulation. (wikipedia.org)
  • Additionally, vervets that were co-administered BMAA with serine were found to have 70% less beta-amyloid plaques and neurofibrillary tangles than those administered BMAA alone, suggesting that serine may be protective against the neurotoxic effects of BMAA. (wikipedia.org)
  • This study also demonstrates that BMAA, an environmental toxin, can trigger neurodegenerative disease as a result of a gene/environment interaction. (wikipedia.org)
  • Most cyanobacteria produce the neurotoxin beta-N-methylamino-l-alanine (BMAA) that has been implicated as a significant environmental risk in the development of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Amyotrophic Lateral Sclerosis (ALS). (wikipedia.org)
  • concentrations
  • Blooms result in reduced dissolved oxygen concentrations, alterations in aquatic food webs, algal scum lining the shores, the production of compounds that cause distasteful drinking water and fish flesh, and the production of toxins severe enough to poison aquatic as well as terrestrial organisms. (wikipedia.org)
  • Antimicrobial susceptibility testing (AST) can be done on 96-well plates by diluting the antimicrobial agent at varying concentrations in broth inoculated with bacteria and measuring the minimum inhibitory concentration that results in no growth. (wikipedia.org)
  • muscle
  • By raising the intake to an average-sized 250-300g portion of turkey a day, the researchers predicted that muscle concentration of beta-alanine might rise by as much as 80% over six months, leading to an even more positive impact on performance. (athleticsweekly.com)
  • This method keeps the body highly sensitive and responsive to insulin resulting in greater lean muscle growth and destruction of fat tissue. (epicsports.com)
  • Incredible Results for Boosting Muscle Mass And Sex Drive. (fav-store.net)
  • Results From My 5 Week Muscle Building Experiment. (gymjunkies.com)
  • Group 1, using the sustained-tension technique, showed the greatest muscle oxygen deficit, suggesting that the localized drop in oxygen levels caused by greater sustained tension, even during lighter exercise, results in gains similar to what you get when you use heavier weights in the conventional training style. (ironmanmagazine.com)
  • Studies show that in addition to helping you train harder and increase your workout endurance, taking a beta alanine supplement can also help you build more muscle. (stayfitcentral.com)
  • Nerves below the head may be compressed where chronic neck and spine problems exist and can be caused by, among other things, muscle cramps that may be a result of clinical anxiety or excessive mental stress,[citation needed] bone disease, poor posture, unsafe heavy lifting practices or physical trauma such as whiplash. (wikipedia.org)
  • deficiency
  • Neurological disorders associated with a deficiency of carnosinase, and the resulting carnosinemia ("carnosine in the blood") are common. (wikipedia.org)
  • Mutations in CNDP1 are responsible for carnosinase deficiency, resulting in carnosinemia. (wikipedia.org)
  • Homocarnosinosis, a neurological disorder resulting in an excess of homocarnosine in the brain, though unaffected by tissue carnosinase, is caused by a deficiency of serum carnosinase in its ability to hydrolyze homocarnosine. (wikipedia.org)
  • A deficiency in this enzyme results in the build-up of non-hydrolyzed mucopolysaccharides in the patient. (wikipedia.org)
  • paraesthesia
  • Most pressure-induced paraesthesia results from awkward posture, such as engaging in cross-legged sitting for prolonged periods of time. (wikipedia.org)
  • metabolic
  • Deficiencies in β-glucuronidase result in the non recessive inherited metabolic disease known as Sly syndrome or Mucopolysaccharidosis VII. (wikipedia.org)
  • synthesis
  • Their result showed the synthesis of 22 amino acids and 5 amines, revealing that the original Miller experiment produced much more compounds than actually known. (wikipedia.org)
  • high
  • These blooms occur as the result of nutrient pollution and degraded water quality, and their growth is further stimulated by high temperatures. (wikipedia.org)
  • found
  • These results were relevant to all forms of cataract, mild or severe, although other studies found the most beneficial effect was in relation to early forms of cataract. (wikipedia.org)
  • substrate
  • thus, the origin of the double bond pi electrons are from the C-H bond on the beta carbon of the substrate. (wikipedia.org)
  • blooms
  • First, this water tends to be rich in nutrients as a result of agricultural runoff, and thus has a tendency to cause algae blooms and other imbalances. (wikipedia.org)
  • Blooms have been reported throughout the continental United States, and resulting cyanotoxins have been associated with human and animal illness and death in at least 43 states. (wikipedia.org)
  • take
  • and to get good results i just take it on an empty stomach about 20-30 minutes before and then take it right after the work out. (bodybuildingweb.net)
  • flood
  • Thus the normal mix of fresh and salt water in those estuaries was replaced by a flood of polluted fresh water resulting in ecological damage. (wikipedia.org)
  • known
  • Both dark chocolate and beetroot juice are known to increase nitric oxide, which is the major mechanism we believe is behind these results," Patel said of his findings, published in the Journal of the International Society of Sports Nutrition . (athleticsweekly.com)
  • Beta-glucuronidase contains several notable structural formations, including a type of beta barrel known as a jelly roll barrel and a TIM barrel. (wikipedia.org)
  • carbon
  • As a result, carbon monoxide binding is only 200 times stronger in haemoglobin, compared to 20,000 times stronger in free haem. (wikipedia.org)