• patient's
  • During these treatments, the patient is connected to an extracoporeal machine, and the patient's blood is pumped through the machine. (google.com)
  • That is not to say that the patient's psychologically induced response may not include physiological effects. (wikipedia.org)
  • For example, it may be used help the patient cope with their disability by better management of rest and activity within the boundaries of the energy constraints of the disorder, and does not actively attempt to improve the patient's physical or psychological capacity. (wikipedia.org)
  • chronic
  • In a prospective trial, 81 patients with chronic hepatitis C (positive hepatitis C virus [HCV] RNA and elevated alanine aminotransferase[ALT] level) and psychiatric disorders (n = 16), methadone substitution (n = 21), former drug addiction (n = 21), or controls without a psychiatric history or drug addiction (n = 23) were treated with a combination of IFN--2a 3 MU 3 times weekly and ribavirin (1,000-1,200 mg/d). (natap.org)
  • rates
  • Suicide rates are nearly twice as high in depressed patients as in the general population. (wikipedia.org)
  • Phase IIb data presented at the 20th Conference on Retroviruses and Opportunistic Infections (CROI) in March 2013 showed similar viral suppression rates of 76% for patients taking 100 mg cenicriviroc, 73% with 200 mg cenicriviroc, and 71% with efavirenz. (wikipedia.org)
  • Non-response rates were higher with cenicriviroc, however, largely due to greater drop-out of patients. (wikipedia.org)
  • Remission rates in various studies using the American College of Rheumatology (ACR) remission criteria 1 have been estimated to be 15% during two to six years of follow up in patients with early disease, 2 18% during 1131 patient-years of follow up, 3 20% during five years of follow up in early disease, 4 and 18% at 10 years of follow up. (bmj.com)
  • outcomes
  • One augmentation will target stasis outcomes through the addition of specific 'if-then' planning (known as implementation intentions) when setting between-session homework and the other augmentation will target patient drop-out by informing patients about group BA effectiveness and therapy-dose evidence. (clinicaltrials.gov)
  • Although at first glance the efficacy of all biologicals appears to be the same, in routine practice one might expect there to be differences in effectiveness, safety profiles and specific patient-centered outcomes. (biomedcentral.com)
  • These patient-centered outcomes, as well as safety, deserve further attention in follow-up registries, but also in prospective studies, if we are to optimize patient care. (biomedcentral.com)
  • Biologicals are often compared solely based on their level of efficacy in RA, by measuring Disease Activity Score and American College of Rheumatology (ACR) responses at fixed time points, without considering differences in mechanisms of action, in efficacy and safety profiles, and in administration, or patient preferences and patient reported outcomes. (biomedcentral.com)
  • Erlotinib
  • In this phase Ib/II study, we aimed to assess the safety and efficacy of afatinib plus nimotuzumab (N) in advanced non-small cell lung cancer (NSCLC) patients with acquired resistance to gefitinib or erlotinib. (aacrjournals.org)
  • Acquired resistance after initial clinical benefit inevitably occurs in patients with EGFR -mutant non-small cell lung cancer (NSCLC), usually within 1 year of starting gefitinib or erlotinib. (aacrjournals.org)
  • PURPOSE: This randomized phase II trial is studying how well giving pemetrexed disodium or docetaxel together with or without erlotinib hydrochloride works in treating patients with stage IIIB or stage IV non-small cell lung cancer. (clinicaltrials.gov)
  • To evaluate the effect of maintenance erlotinib hydrochloride on the response rate to standard of care (pemetrexed disodium or docetaxel) therapy in patients with erlotinib hydrochloride-responsive advanced non-small cell lung cancer as compared to standard of care (pemetrexed disodium or docetaxel) alone. (clinicaltrials.gov)
  • Arm II: (standard of care plus erlotinib): Patients receive pemetrexed disodium IV over 10 minutes OR docetaxel IV over 60 minutes on day 1 and erlotinib hydrochloride orally (PO) once daily on days 2-19. (clinicaltrials.gov)
  • rate among
  • There's little research on the school dropout rate among the general population with which to compare these figures, but Statistics Canada reports that 18% of 20-year-olds have not completed high school. (mentalhealth.com)
  • high
  • However, in most hypertensive patients and particularly in those with associated cardiovascular risk factors or at high risk for cardiovascular events, a combination therapy based on at least two drugs is required in order to achieve the recommended BP goals [ 3 ]. (hindawi.com)
  • The high dropout rate. (bmj.com)
  • This chronology suggests that patients' substance use indeed increases after having experienced trauma, and that high levels of substance use may in turn increase the risk for other traumatic events. (biomedcentral.com)
  • In a further study 5 using the UPSIT together with a match to sample test, patients with multiple sclerosis scored as high as the controls in both procedures. (bmj.com)
  • Patients in the high antibody group had a lower drop out rate and fewer positive cocaine urine results in the last 2 weeks of the trial, but it was not significant versus the low antibody or placebo group. (wikipedia.org)
  • For example, a survey of high school students to measure teenage use of illegal drugs will be a biased sample because it does not include home-schooled students or dropouts. (wikipedia.org)
  • clinic
  • Editorial note: a pilot study from Diana Sylvestri at the OASIS clinic in Oakland finds that with extensive support services patients on methadone maintenance can respond well to HCV therapy even if they relapse into drug use. (natap.org)
  • symptoms
  • To meet criteria for a major depressive episode, a patient must have 5 of these 9 symptoms nearly every day for at least 2 weeks. (wikipedia.org)
  • Because this generation of symptoms entails a complex of "subject-internal" activities, in the strictest sense, we can never speak in terms of simulator-centered "nocebo effects," but only in terms of subject-centered "nocebo responses. (wikipedia.org)
  • CBT based on this model attempts to reverse patients' symptoms by altering their interpretation of their symptoms and/or the behaviours they engage in as a result. (wikipedia.org)
  • dose response
  • Based on the population dose-response model of trough FEV 1 data, the geometric mean potency (ED 50 ) of UMEC was 37 μg (95% confidence interval [CI]: 18, 57) with a predicted maximum intrinsic efficacy (E max ) at trough of 0.185 L (95% CI: 0.153, 0.218) after QD dosing. (springer.com)
  • Although the dose-response curve of UMEC from 62.5 μg to 1000 μg has been examined over 14 [ 6 ] and 28 days [ 8 ], the response obtained over this dosing range was relatively flat. (springer.com)
  • The current study examined the dose-response and safety of UMEC 15.6, 31.25, 62.5, and 125 μg administered once daily (QD), and UMEC 15.6 and 31.25 μg twice daily (BID). (springer.com)
  • See also dose-response. (wikipedia.org)
  • Adverse childhood experiences have a dose-response relationship with many health problems. (wikipedia.org)
  • Methods
  • The purpose of this manuscript is to describe patient-centred approaches used both in developing and testing the Health-E You app and to present the research methods used to evaluate its effectiveness in improving intentions to use an effective method of contraception as well as actual contraceptive use. (bmj.com)
  • The present invention relates generally to patient access disconnection systems and methods for medical treatments. (google.com)
  • METHODS Olfaction was assessed by: (1) The University of Pennsylvania smell identification test (UPSIT, which uses microencapsulated odours that are released when scratched with a pencil) in 72 patients with multiple sclerosis and 96 controls, (2) olfactory evoked potentials (OEP) to 20 ppm H 2 S by volume, and 50% CO 2 in air for 45 patients with multiple sclerosis and 47 controls. (bmj.com)
  • study
  • Almost half of adult patients suffering an anxiety disorder dropped out of school before completing their education, according to a new study from McMaster University. (mentalhealth.com)
  • Between March and October 2008, a total of 240 patients diagnosed for the first time with anogenital warts in the Sexually Transmitted Infections Unit of the "Andreas Sygros" Hospital for Skin and Venereal Diseases were asked to participate in the study. (springer.com)
  • Editorial note from Jules Levin: although this study is small, it finds individuals on methadone maintenance and individuals with psychiatric problems respond as well as HCV-infected patients without these issues. (natap.org)
  • Patients will be asked to provide informed consent to agree for their weekly routine outcome scores from enhanced BAG to be used in the study. (clinicaltrials.gov)
  • However, the first study contained only 25 patients with knee OA followed up for just 6 weeks. (bmj.com)
  • 4 The second study was larger (60 patients) but was of just 1 week's duration and contained a mixed population with knee or hip OA. (bmj.com)
  • 6 This compared paracetamol, diclofenac, and placebo over a 12 week period in 82 patients with knee OA but was the first negative study for paracetamol, showing no difference between paracetamol and placebo using Western Ontario McMaster Osteoarthritis Index (WOMAC) assessments. (bmj.com)
  • Self-selection bias (see also Non-response bias), which is possible whenever the group of people being studied has any form of control over whether to participate (as current standards of human-subject research ethics require for many real-time and some longitudinal forms of study). (wikipedia.org)
  • Excluding subjects who move out of the study area during follow-up is rather equivalent of dropout or nonresponse, a selection bias in that it rather affects the internal validity of the study. (wikipedia.org)
  • The same paper, part of a study funded by the Bill & Melinda Gates Foundation, cited the impact of the Smart Sparrow platform on increasing enrollments and reducing dropouts. (wikipedia.org)
  • disease
  • Atypicals are less likely than haloperidol - the most widely used typical antipsychotic - to cause extrapyramidal motor control disabilities in patients such as unsteady Parkinson's disease-type movements, body rigidity, and involuntary tremors. (wikipedia.org)
  • Pharmacometrics can be defined as that branch of science concerned with mathematical models of biology, pharmacology, disease, and physiology used to describe and quantify interactions between xenobiotics and patients (human and non-human), including beneficial effects and adverse effects. (wikipedia.org)
  • Pharmacometrics uses models based on pharmacology, physiology and disease for quantitative analysis of interactions between drugs and patients. (wikipedia.org)
  • Felitti and Robert Anda from the Centers for Disease Control and Prevention (CDC) went on to survey childhood trauma experiences of over 17,000 Kaiser Permanente patient volunteers. (wikipedia.org)
  • This can result in a spurious negative correlation between diseases: a hospital patient without diabetes is more likely to have another given disease such as cholecystitis, since they must have had some reason to enter the hospital in the first place. (wikipedia.org)
  • cohort
  • In the first dose-finding cohort (afatinib 40 mg plus nimotuzumab 100 mg), one patient experienced dose-limiting toxicity (DLT) of grade 3 diarrhea and in the subsequent cohort (afatinib 40 mg plus nimotuzumab 200 mg), two DLTs (grade 3 diarrhea and grade 3 neutropenia) occurred in 2 of 6 patients. (aacrjournals.org)
  • Statistically
  • For H 2 S, there was a statistically significant increase of latency and decrease of amplitude for patients compared with controls. (bmj.com)
  • clinical trial
  • Although current European League Against Rheumatism (EULAR) 1 and American College of Rheumatology (ACR) 2 guidelines both support paracetamol (acetaminophen) as the first line oral analgesic for patients with knee osteoarthritis (OA), until now there has been a paucity of clinical trial data to confirm the efficacy of paracetamol in large joint OA. (bmj.com)
  • In comparison, in a per-protocol analysis, only patients who complete the entire clinical trial according to the protocol are counted towards the final results. (wikipedia.org)
  • sample
  • However, the average age of the patients with multiple sclerosis was 47 years, whereas that of the controls was 63 years, and there was a preponderance of women in the multiple sclerosis sample which might have masked some abnormalities in multiple sclerosis. (bmj.com)
  • group
  • It is therefore important to develop specific instruments for the measurement of HRQoL in this group of patients. (springer.com)
  • Five patients in this group also had a history of former drug abuse, and 2 patients with schizophrenic disorders additionally received methadone. (natap.org)
  • This is a 6 week double blind parallel group trial of paracetamol versus placebo in 779 patients with knee OA. (bmj.com)
  • characteristics
  • We used the short-form (SF)-36 questionnaire to compare the HRQoL of 91 patients with anogenital warts to 53 control subjects with the same socioeconomic characteristics. (springer.com)
  • effects
  • Physiologically based pharmacokinetic models Exposure-response models describe the relationship between exposure (or pharmacokinetics), response (or pharmacodynamics) for both desired and undesired effects. (wikipedia.org)
  • It has been shown that, due to the nocebo effect, warning patients about side effects of drugs can contribute to the causation of such effects, whether the drug is real or not. (wikipedia.org)
  • physicians
  • This review will, therefore, outline advice to physicians and health-care providers who face this challenging patient population in the EDs. (frontiersin.org)
  • drugs
  • It has been argued that a more nuanced view in which the needs of individual patients are matched to the properties of individual drugs is more appropriate. (wikipedia.org)
  • routine
  • Experience with abatacept in RA is growing thanks to open-label extensions of clinical trials [ 11 ], but published data from routine practice and patient registries are currently lacking. (biomedcentral.com)
  • risk
  • Patients with visits in one quarter had nearly twice the risk of dying compared to patients with visits in all four quarters. (bio-medicine.org)
  • In dementia, they should only be considered after other treatments have failed and if the patient is a risk to himself and/or others. (wikipedia.org)
  • disorder
  • Olfactory disorder was present in only 1% of patients with multiple sclerosis according to one observer. (bmj.com)
  • treatments
  • More specifically, the present invention relates to the detection of patient access disconnection, such as dislodgment of a patient access device during medical treatments or therapies including dialysis therapy. (google.com)
  • A variety of different medical treatments relate to the delivery of fluid to and/or from a patient, such as the delivery of blood between a patient and an extracorporeal system connected to the patient via a needle or needles or any suitable access device inserted within the patient. (google.com)