• The Friend virus (FV) is a strain of murine leukemia virus identified by Charlotte Friend in 1957. (wikipedia.org)
  • The Friend virus has been used for both immunotherapy and vaccines. (wikipedia.org)
  • Experiments have shown that it is possible to protect against Friend virus infection with several types of vaccines, including attenuated viruses, viral proteins, peptides, and recombinant vaccinia vectors expressing the Friend virus gene. (wikipedia.org)
  • By any rational standard, the mRNA vaccines are true vaccines in every sense of the word since they end up educating the human immune system to recognize a specific type of viral protein antigen which then causes this now educated immune system to specifically target the COVID-19 virus prior to an actual infection by the live virus. (educatetruth.com)
  • An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient. (lookformedical.com)
  • An induced state of non-reactivity to grafted tissue from a donor organism that would ordinarily trigger a cell-mediated or humoral immune response. (lookformedical.com)
  • When an isoantigen is encountered by species members who lack it, an immune response is induced. (lookformedical.com)
  • Deliberate prevention or diminution of the host's immune response. (lookformedical.com)
  • The virus infects adult immunocompetent mice and is a well-established model for studying genetic resistance to infection by an immunosuppressive retrovirus. (wikipedia.org)
  • The virus infects adult immunocompetent mice and is a well-established model for studying genetic resistance to infection by an immunosuppressive retrovirus. (wikipedia.org)
  • Human T-cell leukemia virus type I infects human lung epithelial cells and induces gene expression of cytokines, chemokines and cell adhesion molecules. (medscape.com)
  • In a study of vaccinated mice, it was possible to identify the immunological epitopes required for protection against the virus, thus determining the types of immunological responses necessary or required for protection against it. (wikipedia.org)
  • And then we progressed, or moved, from there to studying indigenous viruses of mice, because we were beginning to use mice a lot for experimental purposes, and it became very clear that there were a lot of viruses already in the mice that weren't recognized, hadn't been classified, or tests worked out for their characterization. (nih.gov)
  • And Ludwig Gross's induction of leukemia in mice with AKR thymic lymphomas met the same sort of reaction. (nih.gov)
  • A particular gene of interest is the Rfv-3 gene, which cause susceptibility to suppression of the FV specific antibody response. (wikipedia.org)
  • MicroRNA profile changes in human immunodeficiency virus type 1 (HIV-1) seropositive individuals. (medscape.com)
  • Human immunodeficiency virus type-1 reverse transcriptase exists as post-translationally modified forms in virions and cells. (medscape.com)
  • Intragenic transcriptional cis-activation of the human immunodeficiency virus 1 does not result in allele-specific inhibition of the endogenous gene. (medscape.com)
  • Physical and in silico approaches identify DNA-PK in a Tax DNA-damage response interactome. (medscape.com)
  • However, given the large percentage of patients displaying no response to treatment, real improvements to such approaches are required. (oncotarget.com)
  • And I guess it was a very natural transition from that into the Polyoma virus which was the first real tumor virus that was worked with in this lab. (nih.gov)
  • In one study, never-smokers and regular smokers demonstrated a significant increase in airway resistance in response to e-cigarettes. (lifeextension.com)
  • The role of the humoral immune response in the molecular evolution of the envelope C2, V3 and C3 regions in chronically HIV-2 infected patients. (medscape.com)
  • Confirmed objective responses were reported in 32% of the patients treated with the anti-PD-1, versus 11% in the chemotherapy group. (oncotarget.com)
  • AB - Antibodies against hepatitis E virus (anti-HEV) were found in 248 Swedish and Danish patients between 1993 and 2007. (nih.gov)
  • But I've always felt that one of the key things to sort of opening up tumor virology was the isolation of a virus that you could work with in the lab that produced changes in tissue culture. (nih.gov)