Response to changes hydrogel. Medical search. Frequent questions

In hydrogels the porous permeable solid is a water insoluble three dimensional network of natural or synthetic polymers and a fluid, having absorbed a large amount of water or biological fluids. (wikipedia.org)
The crosslinks which bond the polymers of a hydrogel fall under two general categories: physical hydrogels and chemical hydrogels. (wikipedia.org)
Hydrogels are prepared using a variety of polymeric materials, which can be divided broadly into two categories according to their origin: natural or synthetic polymers. (wikipedia.org)
Hydrogels are crosslinked hydrophilic polymers that undergo swelling in water. (uwaterloo.ca)
Hydrogels, which consist of networks of watery polymers, have come to offer a delivery vehicle with plenty of potential in this area, keeping the drugs stable and intact until they reach their destination. (newatlas.com)
The team's hydrogel is made from synthetic polymers and organic compounds and incorporates amino groups. (newatlas.com)
Hydrogel polymers present a versatile coating option for electrodes as they can be chemically modified to provide a soft and conductive scaffold. (frontiersin.org)
We construct a mesoscopic model of rigid NPs entrapped in a hydrogel network in an aqueous solution, where the hydrogel network is formed by cross-linked semiflexible polymers of thermoresponsive poly( N -isopropylacrylamide) (PNIPAM). (rsc.org)
Approaches to reconstruction have used mainly synthetic scaffolds such as polymers and hydrogels, as well as natural scaffolds of collagen origin. (bvsalud.org)

In this mini-review, we highlight the recent progress in GO-incorporated hydrogels for biomedical applications while focusing on their specific uses as mechanically strong materials, electrically conductive scaffolds/electrodes, and high-performance drug delivery vehicles. (nature.com)
Among different types of scaffolds, polymeric hydrogel scaffolds have received considerable attention because of their biocompatibility and structural similarity to native tissues. (mdpi.com)
However, hydrogel scaffolds have several limitations, such as weak mechanical property and a lack of bioactive property. (mdpi.com)

A key area in the repair and regeneration of tissues is optimizing the polymeric scaffold-tissue response. (nist.gov)
Successful means of translating such optimised responses to complex polymeric matrices have proved significantly more difficult. (dcu.ie)

Quantitative results on the mean-squared displacement and the van Hove displacement distributions of NPs show that all NPs entrapped in the smart hydrogels undergo subdiffusion at both low and high temperatures. (rsc.org)

To test how well their AAD closed wounds, the researchers tested it on patches of mouse skin and found that it reduced the size of the wound area by about 45 percent compared to almost no change in area in the untreated samples, and closed wounds faster than other treatments including microgels, chitosan, gelatin, and other types of hydrogels. (medicaldesignbriefs.com)
Characterization studies were performed using physically and chemically crosslinked hydrogel systems, including gelatin hydrogels (6-10 wt. (aip.org)

Montheil T, Echalier C, Martinez J, Subra G, Mehdi A. Inorganic polymerization: an attractive route to biocompatible hybrid hydrogels. (nature.com)
The researchers knew from toxicity literature that their hydrogel capsules would be biocompatible, and would behave in a syringe. (nanowerk.com)
Researchers test a sampling of synthetic, biocompatible hydrogels to see how tuning them influences the body's inflammatory response. (materialstoday.com)
Previous strategies to avoid the negative results of the immune response to implants primarily involved hiding the implant from the immune system by using relatively inert or biocompatible implants to prevent or mitigate the negative aspects of chronic inflammation. (medscape.com)
Here, I developed a new class of tissue-specific PEG-based materials and provided biocompatible strategies to improve the user handling and cell viability post-encapsulation when using these hydrogels. (umass.edu)

Preliminary studies showed varied mechanical response but that cells wre completely viable in both types of hydrogels after two weeks. (nist.gov)

Herein, we synthesize chemically crosslinked PNIPAAm porous hydrogels made of nanofiber mats. (elsevierpure.com)

And once the job is done, the hydrogel degrades into water-soluble oligomers and can be easily excreted from the body. (newatlas.com)
The in situ formed hydrogel encapsulates the therapeutic molecule and releases the agent over time as the hydrogel degrades. (ophthalmologytimes.com)
This thesis explored the inclusion of functional groups that enable water solubility and cross-linking through click reactions, resulting in a self-immolative hydrogel that degrades upon UV light irradiation. (uwo.ca)

Enhancing the physiological relevance of the model alleviated cell toxicity and was more reflective of the reported in vivo response. (nottingham.ac.uk)

Purpose: To compare central corneal swelling (CS) after eight hours of sleep in eyes wearing 12 different silicone hydrogel (SiHy) contact lenses (CLs) and to model between-subject variability in CS and deswelling. (uwaterloo.ca)

Chemical hydrogels have covalent cross-linking bonds, whereas physical hydrogels have non-covalent bonds. (wikipedia.org)

Therefore, understanding the cellular response to changes in soluble cues through their biomaterial microenvironment, such as oxygen concentration, is crucial for engineering materials that can more closely mimic conditions in vivo and that can potentially lead for improving methods for control over cell behavior in tissue engineering. (aiche.org)
Song F, Li X, Wang Q, Liao L, Zhang C. Nanocomposite hydrogels and their applications in drug delivery and tissue engineering. (nature.com)
Whereas natural hydrogels are usually non-toxic, and often provides other advantages for medical use, such as biocompatibility, biodegradability, antibiotic/antifungal effect and improve regeneration of nearby tissue, their stability and strength is usually much lower than synthetic hydrogels. (wikipedia.org)
The use of hybrid self-assembling peptide (EFK8)-carbon nanotube (SWNT) hydrogels for tissue engineering and in vitro 3D cancer spheroid formation is reported. (uwaterloo.ca)
[ 1 ] All implanted materials can be recognized by the patient's immune system as foreign bodies causing cellular and tissue immune responses. (medscape.com)
Hydrogels, as a class of materials for tissue engineering and drug delivery, have high water content and solid-like mechanical properties. (eurekaselect.com)
The limitations of interfacing electrodes including low charge injection limits, mechanical mismatch and foreign body response can be addressed through the use of organic electrode coatings which typically provide a softer, more roughened surface to enable both improved charge transfer and lower mechanical mismatch with neural tissue. (frontiersin.org)
A more recent approach proposes tissue engineering the electrode interface through the use of encapsulated neurons within hydrogel coatings. (frontiersin.org)
Hydrogels possess a comfortable degree of flexibility similar to natural tissue, due to their significant water content. (ophthalmologytimes.com)
Polyethylene glycol (PEG) hydrogels are tunable cell culture platforms that recapitulate tissue geometry, water content, and bulk modulus. (umass.edu)
While PEG hydrogels can easily be tuned to mimic tissue mechanics, most PEG platforms contain between 1-3 biofunctional peptide moieties, chosen to maximize cell phenotype, rather than represent features of specific tissues. (umass.edu)
Bioinformatics on human tissue histology identified 20 different cell-instructive peptides that represent the protein signature of bone marrow and can be incorporated into a hydrogel matched to the compressive modulus of marrow. (umass.edu)
Compared to a non-tissue specific hydrogel, the marrow-customized hydrogel provides a better niche for bone marrow-derived mesenchymal stem cell differentiation and proliferation in response to soluble cues. (umass.edu)
I also highlighted how tissue-inspired hydrogels can improve in vitro studies of cell-cell and cell-matrix interactions. (umass.edu)
8,9 3D printing of nanocellulose hydrogels is being used in biomedical applications to support living cell growth for tissue engineering, implants, and cardiovascular devices. (cdc.gov)

The Global Market for Hydrogels 2024-2034 provides a comprehensive analysis of the global hydrogel landscape, technologies, companies, and applications across major industry verticals. (researchandmarkets.com)
The report also provides a segment-wise and region-wise breakup of the global hydrogel adhesive industry. (imarcgroup.com)

Preparation and enhanced mechanical properties of hybrid hydrogels comprising ultralong hydroxyapatite nanowires and sodium alginate. (nature.com)

NHLFs were grown on polyacrylamide (PAAm) hydrogels with the stiffness comparable to that of human normal and fibrotic lung tissues, and treated with MWCNTs for various time. (cdc.gov)

These findings provide new insights for designing controlled drug release from stimuli-responsive hydrogels, including autonomously switch on/off drug release in response to physical and chemical stimuli. (rsc.org)

However, the foreign body response (FBR) is reported to interfere with sustained release mechanisms and is a major factor in determining the efficacy of depot formulations. (nottingham.ac.uk)
There is a rising interest in eco-friendly, biodegradable hydrogel adhesive formulations to reduce environmental impact and meet sustainability goals. (imarcgroup.com)
6,7] Unlike older alcohol-based gel formulations, which could be drying to dermatitic skin, the hydrogel vehicle has been shown to increase epidermal moisturization. (jcadonline.com)
It was found that formulations of higher polymer content produced hydrogels that degraded upon UV light irradiation, showing promise for future applications. (uwo.ca)

There are also synthetic hydrogels than can be used for medical applications, such as polyethylene glycol (PEG), polyacrylate, and polyvinylpyrrolidone (PVP). (wikipedia.org)
One deliverable of this effort is a proprietary polyethylene glycol (PEG) hydrogel platform technology (Ocular Therapeutix). (ophthalmologytimes.com)

Many advanced antibacterial hydrogels have been developed, each possessing unique qualities, namely high water swellability, high oxygen permeability, improved biocompatibility, ease of loading and releasing drugs and structural diversity. (eurekaselect.com)
Ongoing research and development activities are leading to the creation of hydrogel adhesives with improved properties, including enhanced biocompatibility, controlled drug release, and extended wear times. (imarcgroup.com)

Functionalized carbon nanotube and graphene oxide embedded electrically conductive hydrogel synergistically stimulates nerve cell differentiation. (nature.com)
However, the in vivo chronic inflammatory response of these conductive hydrogels remains unknown. (frontiersin.org)

Highly swollen crosslinked hydrophilic copolymers called "hydrogels" are synthesized by free radical crosslinking copolymerization with some multifunctional crosslinkers with some co-monomers including hydrophilic groups for increasing of their swelling capacity. (scirp.org)

Methods of synthesis of hydrogels … a review. (nature.com)

In vitro models offer the capacity to screen many test conditions to predict the complex and multifaceted immune response, although no established in vitro FBR model exists. (nottingham.ac.uk)
Hence, the overarching aim of this thesis was to develop an in vitro model that recapitulated characteristic elements of the FBR and adapt it to study the potential effect of FBR towards injectable hydrogel materials. (nottingham.ac.uk)
However, further adaptations are required to incorporate weak injectable hydrogels into in vitro models long-term to enable screening of the resultant FBR. (nottingham.ac.uk)

The current study includes the preparation/characterization of a series of polyethylen glycol (PEG) dimethacrylate, their conversions in aqueous solution to photopolymerization, and a preliminary assessment of the correlation of mechanical and cell response to hydrogel structural variations. (nist.gov)
Aqueous solutions of these dimethacrylates (10% by mass fraction in water) were photopolymerized to hydrogels. (nist.gov)
Desonide is a low-potency corticosteroid recently formulated in a novel aqueous gel (hydrogel) formulation. (jcadonline.com)
4,5]Advances in formulation technology have enabled the development of desonide into a novel aqueous gel (hydrogel) that is alcohol-free and disappears quickly without leaving a greasy residue. (jcadonline.com)

Hydrogels incorporating nanoparticles (NPs) possess new properties that can revolutionize areas such as drug delivery, protein crystallography, and self-assembly of photonic crystals. (confex.com)
Understanding the drug release kinetics and corresponding transport mechanisms of nanoparticles (NPs) in a thermoresponsive hydrogel network is the key to the successful design of smart drug delivery systems. (rsc.org)

A new, scalable approach to speeding up wound healing has been developed based on heat-responsive hydrogels that are mechanically active, stretchy, tough, highly adhesive, and antimicrobial: active adhesive dressings (AADs). (medicaldesignbriefs.com)
Active adhesive dressings are based on heatresponsive hydrogels that are mechanically active, stretchy, tough, highly adhesive, and antimicrobial. (medicaldesignbriefs.com)
IMARC Group's report, titled "Hydrogel Adhesive Manufacturing Plant Project Report 2024: Industry Trends, Plant Setup, Machinery, Raw Materials, Investment Opportunities, Cost and Revenue " provides a complete roadmap for setting up a hydrogel adhesive manufacturing plant . (imarcgroup.com)
Hydrogel adhesive, at the intersection of materials science and medical innovation, represents a remarkable breakthrough in the realm of adhesives. (imarcgroup.com)
This cutting-edge adhesive is designed with hydrogel, a water-absorbing polymer, as its core component, offering unique properties that make it invaluable in the healthcare field. (imarcgroup.com)
Hydrogel adhesive is revolutionizing wound care, medical device attachment, and drug delivery systems. (imarcgroup.com)
In this exploration, we delve into the world of hydrogel adhesive, unveiling the science behind its remarkable properties, its diverse applications in healthcare, and its profound impact on patient comfort, treatment efficacy, and the future of medical adhesives. (imarcgroup.com)
Hydrogel adhesive is also used in medical electrodes for secure, comfortable attachment to the skin during diagnostics. (imarcgroup.com)
The market for hydrogel adhesive is experiencing rapid growth, driven by a convergence of factors such as healthcare advancements, changing demographics, and technological innovation. (imarcgroup.com)
Hydrogel adhesive is integral in diabetic wound management, contributing to healing and infection prevention. (imarcgroup.com)
The continuous expansion of telemedicine and remote patient monitoring is driving the demand for hydrogel adhesive-based sensors, ensuring accurate data collection from patients at home. (imarcgroup.com)
The report provides insights into the landscape of the hydrogel adhesive industry at the global level. (imarcgroup.com)
Additionally, it also provides the price analysis of feedstocks used in the manufacturing of hydrogel adhesive , along with the industry profit margins. (imarcgroup.com)
The report also provides detailed information related to the hydrogel adhesive manufacturing process flow and various unit operations involved in a manufacturing plant. (imarcgroup.com)

abstract = "Poly(N-isopropylacrylamide)(PNIPAAm) hydrogel is thermo-sensitive, and undergoes a volume phase transition from a swollen state to a shrunken state. (elsevierpure.com)

Novel sorbent hydrogels containing acrylamide/sodium vinylsulfonate, carboxymethyl cellulose and zeolite were synthesized with free radical solution polymerization by using ammonium persulfate/ N , N , N' , N' -tetramethylethyle - nediamine as redox initiating pair in presence of poly(ethylene glycol) diacrylate as crosslinker. (scirp.org)

The AAD also did not cause inflammation or immune responses. (medicaldesignbriefs.com)

A synthetic actuator made from thermo-responsive liquid crystal polymer networks and a coat of dye can learn to bend and walk in response to light. (materialstoday.com)
Through the stimulus-responsive trigger, these materials can decompose rapidly in response to triggers, such as UV light irradiation. (uwo.ca)
ORCID: 0000-0003-2944-4839 (2018) Boronic acids for the generation of responsive hydrogels. (dcu.ie)

Here, we demonstrate an injectable filamentous hydrogel depot (FM-depot) engineered for low dosage, sustained delivery of anti-inflammatory nanocarriers. (frontiersin.org)

When a water-miscible non-solvent is added to water, the water-swollen hydrogel often shrinks or collapses. (scirp.org)

A key requirement for their successful utilization into many target applications is the understanding of how the spatial arrangement of the NPs contributes to the mechanical properties of the hydrogel. (confex.com)
By analytically investigating the ratio of configurational transformations from three-point to single-point bonding, we demonstrate how the macro-mechanical properties of NP hydrogels can be influenced by the configurable coordination between molecules. (confex.com)

The POSTECH researchers claim that this chitosan (a biodegradable polymer) hydrogel film can quickly swell and contract like a super sponge: it can absorb water around it at nearly 1,000 weight percentage of its dried weight. (allaboutcircuits.com)

Here, we report for the first time that resonance in dynamic-mode cantilever sensors persists in hydrogels and enables the real-time characterization of hydrogel viscoelastic properties and the continuous monitoring of sol-gel phase transitions (i.e., gelation and dissolution processes). (aip.org)

Hydrogels are cross-linked hydrophilic polymer networks with low optical background and high loading capacity for immobilization of biomolecules. (uwaterloo.ca)

citation needed] Chemical hydrogels can result in strong reversible or irreversible gels due to the covalent bonding. (wikipedia.org)
Chemical hydrogels that contain reversible covalent cross-linking bonds such as hydrogels of thiomers being cross-linked via disulfide bonds are non-toxic and are used in numerous medicinal products. (wikipedia.org)
We show experimentally that chemical and mechanical self-oscillations in Belousov−Zhabotinsky hydrogels are inherently asynchronous, that is, there is a detectable delay in swelling−deswelling response after a change in the chemical redox state. (reading.ac.uk)
As a result, the volume response of the polymer to a chemical change may be governed by a characteristic response time, which leads to the emergence of delay in mechanical oscillation. (reading.ac.uk)
Scientists have developed many kinds of hydrogels that respond in specific ways to chemical signals. (nanowerk.com)
Hydrogels could even to tune themselves over time and space to modify the rate of chemical reactions. (nanowerk.com)
In biological organisms, materials convert stimuli into chemical reactions, changes in shape, and other responses. (nanowerk.com)
However, sending the copper or acid stimuli sequentially caused the hydrogel to respond with a cascading series of energy conversion reactions in the form of brief bursts of competing localized chemical and mechanical energy flows. (nanowerk.com)

Thermoresponsive hydrogels have been studied intensively for creating smart drug carriers and controlled drug delivery. (rsc.org)

The innate immune system triggers the body's "emergency response" to invaders such as infections. (genengnews.com)

Hydrogels are three-dimensional networks of hydrophilic polymer chains with properties in between liquids and solids. (scirp.org)

In response to changing humidity, the chitosan hydrogel swells and contracts. (allaboutcircuits.com)

Unique molecular interactions between graphene derivatives and various small or macromolecules enable the fabrication of various functional hydrogels appropriate for different biomedical applications. (nature.com)
Recent developments in tough hydrogels for biomedical applications. (nature.com)
Hydrogels for biomedical applications. (nature.com)
Chai Q, Jiao Y, Yu X. Hydrogels for biomedical applications: their characteristics and the mechanisms behind them. (nature.com)
Biomedical applications of hydrogels: a review of patents and commercial products. (nature.com)

This enables them to shrink and swell in response to both changing temperatures and pH levels, and release their drugs as a result. (newatlas.com)
Our hydrogels rapidly shrink without the two-step shrinking. (elsevierpure.com)
Scientists previously had not considered that hydrogels could do more than simply shrink and expand in phase with specific stimuli. (nanowerk.com)

This unique antibody binds to a receptor associated with mediating immune responses to tumor cells, and is used in a range of sometimes intractable cancers. (nanowerk.com)

Hydrogel: preparation, characterization, and applications: a review. (nature.com)

To conduct a pilot study evaluating efficacy, tolerability, and patient preference of desonide hydrogel 0.05% for the treatment of scalp and facial seborrheic dermatitis. (jcadonline.com)
Desonide hydrogel 0.05% may provide an effective, well-tolerated, and cosmetically elegant treatment option for scalp and facial seborrheic dermatitis. (jcadonline.com)
The purpose of this four-week, open-label, pilot study was to explore the potential suitability of desonide hydrogel 0.05% for the treatment of scalp and facial SD by evaluating efficacy, tolerability, and patient preference. (jcadonline.com)
Eligible subjects were treated twice daily with desonide hydrogel 0.05% for four weeks. (jcadonline.com)

Alginate hydrogels are formed by ionic interactions between alginate and double-charged cations. (wikipedia.org)
In a recent paper published in Advanced Healthcare Materials ( 'Crystalline Antibody-Laden Alginate Particles: A Platform for Enabling High Concentration Subcutaneous Delivery of Antibodies' ), these researchers describe a hydrogel platform for delivering monoclonal antibodies (MABs) - one type of biologic - through subcutaneous injection. (nanowerk.com)

There are two suggested mechanisms behind physical hydrogel formation, the first one being the gelation of nanofibrous peptide assemblies, usually observed for oligopeptide precursors. (wikipedia.org)

Results: Increased copolymer hydrophobicity correlated with increased hydrogel moduli and a lower temperature was required to initiate gelation. (nottingham.ac.uk)
Q air = 23.8 ± 1.5) enabled continuous monitoring of high-frequency hydrogel shear storage and loss moduli ( G′ f and G″ f , respectively) calculated by sensor data and fluid-structure interaction models. (aip.org)

Typically, after immersing poly(N-isopropylacrylamide) hydrogels into hot water above the critical temperature, they undergo a two-step shrinking process, which leads to very slow dynamics. (elsevierpure.com)

One of the advantages of hydrogels consists in their capability of high swelling and in exhibiting a first-order phase transition (collapse) caused by a small change in external conditions such as temperature, electric ﬁeld, solvent composition, etc. [14] - [19]. (scirp.org)

We also present the construction of a correlation between changes in the expression of the EGFP-HIF-1alpha fusion protein and gradients in oxygen concentration through the volume of hydrogel scaffold. (aiche.org)

For an ovalbumin ( OVA )-imprinted hydrogel layer, functional monomers were employed to achieve sufficient binding effect in the polymer matrix. (bvsalud.org)

In: Emerging concepts in analysis and applications of hydrogels. (nature.com)
Hydrogels as emerging materials for translational. (nature.com)

However, when the solution temperature is increased above the critical temperature, the hydrogel network collapses following the coil-to-globule transition, with the NPs tightly trapped in some local regions inside the hydrogels. (rsc.org)

Mechanical stimulation led to a significant increase in chondrogenic gene expression, while histological analysis detected sulphated glycosaminoglycans and collagen II only in loaded specimens, confirming MC hydrogel suitability to support load induced MSCs chondrogenesis. (nature.com)
The fibrogenic responses, including cell proliferation, reactive oxygen species production, and collagen I expression, of NHLFs to MWCNTs were observed to be regulated by substrate stiffness in a time-dependent manner. (cdc.gov)

Physically crosslinked hydrogels can be prepared by different methods depending on the nature of the crosslink involved. (wikipedia.org)

The combination of PET, M-CSF and IL-4 induced 90.6% ± 3.2% macrophages to fuse into FBGCs after 28 days, the process of which was associated with a specific programme of soluble mediators characterised by an initial pro-inflammatory response that shifted towards wound healing. (nottingham.ac.uk)
Cardiovascular immunotherapy has therefore become a recent focus for treatment, with the objective to develop approaches that can suppress excessive inflammatory responses by modulating specific immune cell populations. (frontiersin.org)
If we can somehow modulate the activation of this pathway, then that will help to decrease the exaggerated inflammatory response that causes mortality during influenza infection. (genengnews.com)
Through containment, localization, and protection from inflammatory response, the hydrogel expands the utility of therapeutic molecules via more effective and consistent delivery. (ophthalmologytimes.com)

Here, we investigated the effects of substrate stiffness on the fibrogenic responses of normal human lung fibroblasts (NHLFs) to multiwalled carbon nanotube s (MWCNTs). (cdc.gov)

Thus, HIF-1alpha is an ideal marker for correlating cellular response to oxygen concentration in engineered tissues. (aiche.org)
The company has created a way to encapsulate a wide range of pharmaceuticals within its hydrogel to provide targeted, sustained delivery of therapeutic levels of drugs to ocular tissues. (ophthalmologytimes.com)
Most living tissues exhibit the specific stiffness, which has been known to have profound influence on cell behaviors, yet how the stiffness affects cellular responses to engineered nanomaterial s has not been elucidated. (cdc.gov)

Graphene and graphene derivatives (e.g., graphene oxide (GO)) have been incorporated into hydrogels to improve the properties (e.g., mechanical strength) of conventional hydrogels and/or develop new functions (e.g., electrical conductivity and drug loading/delivery). (nature.com)
Fu J, In Het Panhuis M. Hydrogel properties and applications. (nature.com)
Improving hydrogels' toughness by increasing the dissipative properties of their network. (nature.com)
The effect of modifying copolymer properties on hydrogel gelation was characterised by rheology. (nottingham.ac.uk)
The properties of a hydrogel are highly dependent on the type and quantity of its crosslinks, making photopolymerization a popular choice for fine-tuning hydrogels. (wikipedia.org)
This study is designated to better understand the relationships between polymer matrix structure and properties to cell response. (nist.gov)
Hydrogels prepared from these dimethacrylates can provide a basis for the understanding how their material properties influence the cell response. (nist.gov)
This means the hydrogel can be specifically programmed for a variety of disease states depending on the molecule's properties and the desired duration of therapy required. (ophthalmologytimes.com)
Further investigation into these hydrogels' physical properties is warranted to understand their potential applications fully. (uwo.ca)

Our findings are confirmed by Monte Carlo simulations of the formation and mechanical response of hydrogels with different molecular interactions. (confex.com)
Elucidating and controlling the response of molecules and molecular assemblies to forces and the implications of this response at multiple hierarchical length scales is of crucial importance for understanding the behavior of materials of both biological and synthetic origin. (grc.org)

In this method, photoinitiators, compounds that cleave from the absorption of photons, are added to the precursor solution which will become the hydrogel. (wikipedia.org)
The OVA amount added in the MIP precursor solution and the dimensions of OVA -imprinted hydrogel (MIH) strips were controlled to maximize the change in bending angles as an OVA sensing response within a valid detection range. (bvsalud.org)

The primary objective of this GRC is to bring together biologists, biochemists, chemists, materials scientists and engineers for a cross-disciplinary discussion on how molecules and their higher-order assemblies respond to forces and how this response influences material behavior at multiple hierarchical levels. (grc.org)

The combination of new time- and spatial-resolved experimental methods combined with computational and theoretical approaches is required to determine the complex nonlinear and time-varying response to deformations which is often also non-homogeneous. (lu.se)

A hydrogel is a biphasic material, a mixture of porous, permeable solids and at least 10% by weight or volume of interstitial fluid composed completely or mainly by water. (wikipedia.org)
The response of this porous gel is over 100 times faster than that of the typical gel. (elsevierpure.com)

Anatomy2

Chemicals and Drugs29

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Phenomena and Processes9

Disciplines and Occupations2

Technology, Industry, Agriculture17

Health Care1

Polymers9

Scaffolds3

Polymeric2

Smart Hydrogels1

Gelatin2

Biocompatible5

Types of hydrogels1

Chemically crosslinked1

Degrades3

Toxicity1

Silicone hydrogel1

Physical Hydrogels1

Tissue15

Global hydrogel2

Hybrid hydrogels1

Polyacrylamide1

Stimuli responsive1

Formulations4

Polyethylene2

Biocompatibility2

Conductive2

Copolymers1

Synthesis1

Vitro3

Aqueous4

Nanoparticles2

Adhesive14

Abstract1

Sodium1

Inflammation1

Responsive3

Injectable1

Shrinks1

Mechanical properties2

Biodegradable1

Sensors1

Polymer Networks1

Chemical8

Thermoresponsive1

Body's1

Hydrophilic polymer1

Chitosan1

Biomedical applications5

Shrink3

Immune responses1

Characterization1

0.054

Alginate2

Peptide1

Moduli2

Undergo1

Solvent composition1

Scaffold1

Monomers1

Emerging2

Collapses1

Collagen2

Physically1

Inflammatory4

Fibroblasts1

Tissues3

Properties9

Molecular2

Precursor2

Molecules1

Methods1

Porous2