• The plant response to biotic and abiotic stress has been studied for many years, but the molecular mechanism controlling touch-signalling in plants is not well understood. (lu.se)
  • The researchers were able to quantify this behavior and developed a mathematical model that can predict the intensity of the glow based on the magnitude of the mechanical stress applied. (sciencedaily.com)
  • The mechanical behavior of these composites depends in interesting ways on the elasticity of the matrix. (aps.org)
  • As such the mechanochemical behavior of a solid-state polymer is highly sensitive to stress carried by that polymer, including local spatial and temporal fluctuations. (aps.org)
  • The effect of each is found to be significant and highly dependent on the intrinsic polymer mechanical behavior. (aps.org)
  • This instrument offers insights into measuring the mechanical behavior during an electrode's charging and discharging, which can be challenging to observe in real-time. (tamu.edu)
  • A study of ground behavior, reinforcement performance and stress redistribution looked at a longwall tailgate under severe horizontal stress. (cdc.gov)
  • The stepwise quenching-recovery cycles induced by the mechanical action is interpreted as a modulation of the PL blinking behavior. (lu.se)
  • We demonstrate how we can harness the power of nature to directly convert mechanical stimuli into light emission. (sciencedaily.com)
  • This current work demonstrates a simple method to combine living organisms with non-living components to fabricate novel materials that are self-sustaining and are sensitive to fundamental mechanical stimuli found in nature," said study first author Chenghai Li, a mechanical and aerospace engineering Ph.D. candidate in Cai's lab. (sciencedaily.com)
  • Bone density is increased in response to mechanical stimuli and reduced when physical activity is reduced. (cornell.edu)
  • While these processes are well recognized at the scale of the whole bone, they have never been studied at the scale of individual bone cells, making it unclear what mechanical stimuli are most influential in controlling bone adaptation (strain, fluid shear, etc). (cornell.edu)
  • To understand the mechanism of cartilage degeneration and remodeling, it is important to know the mechanical stimuli to chondrocytes for physiological loading conditions. (cdc.gov)
  • Fluid pressure and stress-strain state in and around chondrocytes are important mechanical stimuli associated with remodeling, adaptation. (cdc.gov)
  • Texas A&M College of Engineering professors Drs. Dimitris Lagoudas, Jodie Lutkenhaus and James Boyd have discovered how to measure mechanical stresses and strains in energy storage materials. (tamu.edu)
  • To combat this, her research looks to create an instrument that measures mechanical stresses and strains in energy storage materials as they charge and discharge. (tamu.edu)
  • While compression induces the usual Hookian elastic response (for strains or stresses that are not too large), tension leads to square-lattice wave undulations in the transverse directions when the strain exceeds a critical value. (caltech.edu)
  • It was our objective to study the role of mechanical stimulation on fibronectin (FN) reorganization and recruitment by exposing fibroblasts to shear fluid flow and equibiaxial stretch. (nature.com)
  • Complimentary to this, fibroblasts exposed to fluid shear stress structurally rearranged pre-coated surface FN, but unstimulated and stretched cells did not. (nature.com)
  • For seismic load, the S-wave and P-wave acting on the subgrade will be in random combination with different amplitudes, frequencies, and loading orders, while the CCP condition can only simulate a specific combination of normal stress and shear stress. (hindawi.com)
  • AVM cells were isolated from three patients and exposed to cyclic mechanical stretching for 24 h. (researchgate.net)
  • 48,49 In addition, cyclic mechanical strain enhances the function and development of engineered tissues by improving the production of collagen and elastin. (researchgate.net)
  • 43 Therefore, cell sheets with enhanced thickness and mechanical properties obtained through appropriate cyclic mechanical stimulation possess great potential for bone tissue engineering applications. (researchgate.net)
  • Graphical abstract Mechanical stress increases VEGF expression in endothelial AVM cells, possibly causing the VEGF upregulation in the microenvironment of AVM cells. (researchgate.net)
  • In this work we first address the problem of the scale of homogeneity of these discrete systems, i.e. the size of the model above which the elastic response is model size- independent. (aps.org)
  • In this paper, an elastodynamic formulation was employed to investigate the dynamic response of a homogeneous isotropic elastic half-space under an inertial strip foundation subjected to a time-harmonic force. (scielo.br)
  • The researchers envision that these materials could potentially be used as mechanical sensors to gauge pressure, strain or stress. (sciencedaily.com)
  • Dynamic Mechanical Analysis (DMA) is a testing technique and related analytical instrument that measures the physical properties of solids and polymer melts, reports modulus and damping, and is programmable to measure force, stress, strain, frequency and temperature. (instron.com)
  • Bone has the capacity to respond to mechanical stress and strain. (cornell.edu)
  • The student will write software to perform three-dimensional image registration to spatially associate bone formation with tissue and fluid mechanical stress and strain (achieved from high-resolution finite element models). (cornell.edu)
  • We compared equivalent stress and strain energy density (SED) to bone mineral density (BMD) in the femur after total hip arthroplasty (THA) using subject-specific finite element analysis (FEA). (intechopen.com)
  • such a melting can take the form of three types of instabilities, a quasithermodynamic instability, a spinodal at controlled strain, and a mechanical instability at controlled stress. (caltech.edu)
  • This deformation can be followed by a subsequent melting of types similar to the compressional case, upon further increase of the stress or strain. (caltech.edu)
  • The purpose of the present study was to simulate numerically the location- and time-dependent stress-strain state and fluid pressure distribution in chondrocytes in unconfined compression tests under cyclic loading conditions. (cdc.gov)
  • Some evidence indicates that bone natural curvatures may restrict tissue deformation during mechanical load, so the bone tissue becomes more adapted and resistant to a normal pattern of strain distribution 8 . (bvsalud.org)
  • While mitotic spindles have been shown to reorient in response to external mechanical stresses, the subcellular cues that mediate spindle reorientation remain unclear. (unige.ch)
  • Plants use such mechanical cues to detect e.g. herbivores, wind, neighbouring plants or to find supports to climb on. (lu.se)
  • In one case they studied, chemical tags regulate the stress response to drought by closing the stomata and lengthening the primary root. (evolutionnews.org)
  • Oxidative stress pathways regulate redox balance by Nrf2 and other ways. (springer.com)
  • Collectively, these studies provide new insights regarding the molecular mechanisms that regulate heart valve response to mechanical stress. (drugdiscoverynews.com)
  • While the primary roots did not response to a restriction in growth of the seminal roots, seminal roots reacted to the applied stress in the same way as the impeded roots, even if the stress did not occur in their environment. (slu.se)
  • Internal stresses occur when batteries develop a repeated cycling of the device, while external stresses can result from impact or penetration of the device. (tamu.edu)
  • Among these mesophases, inverse bicontinuous cubic phase Q II membranes have been found to spontaneously occur in stressed or virally infected cells and to play a role in fundamental processes, such as cell fusion and food digestion. (lu.se)
  • Mechanical damage limits the cycle life of batteries, so new hardware and models are needed to interpret experimental measurements to separate the effects of mass diffusion, reactions, inelastic deformation and mechanical damage. (tamu.edu)
  • Usually, anomalies found within the breast are investigated by palpation techniques, in which responses of soft tissue to large deformation are utilized (Goodson, 1996). (bartleby.com)
  • In this review, we studied on the effects and molecular mechanisms of Rhizoma coptidis on NF-κB/MAPK/PI3K-Akt/AMPK/ERS and oxidative stress pathways. (springer.com)
  • Evidence presented in this review implicated that Rhizoma coptidis exerted beneficial effects on various diseases by regulation of NF-κB/MAPK/PI3K-Akt/AMPK/ERS and oxidative stress pathways, which support the clinical application of Rhizoma coptidis and offer references for future researches. (springer.com)
  • Oxidative stress pathways are caused by the imbalance of oxidation and antioxidation in body. (springer.com)
  • In this review, we sorted out the relationship of Rhizoma coptidis among components, diseases and NF-κB/MAPK/PI3K/Akt/AMPK/ERS/oxidative stress pathways, systematically studying on how Rhizoma coptidis exerts beneficial effects to various diseases, which supported the clinical application of Rhizoma coptidis and provided references for the future researches. (springer.com)
  • 50 Moreover, the mechanical properties of engineered tissues can also be improved by culturing under mechanical stimulation. (researchgate.net)
  • When this has been accomplished, the body ordinarily stops the inflammatory response to prevent damage to its own cells and tissues. (medlineplus.gov)
  • Dynamic Compressive Loading Improves Cartilage Repair in an in vitro Model of Microfracture: Comparison of Two Mechanical Loading Regimens on Simulated Microfracture Based on Fibrin Gel Scaffolds Encapsulating Connective Tissue Progenitor Cells. (chop.edu)
  • The Piezo1 and Piezo2 ion channels are known to open up response to the slightest mechanical stimulus. (phys.org)
  • Therefore, it was hypothesized that mechanical load arising in the mandibular ramus during mastication would generate the physiologic stimulus for bone remodeling and mandibular growth. (bvsalud.org)
  • Furthermore, bone curvatures tend to amplify the functional stimulus produced by mechanical loads 9-10 . (bvsalud.org)
  • It also engages essential stretch-sensing properties of the muscle, which convert mechanical stress into responses that promote muscle growth. (acsm.org)
  • Mechanical stimulation was also combined with a Rho inhibitor to probe their coupled effects on FN. (nature.com)
  • Mechanical stimulation coupled with chemical stimulation also revealed an increase in FN fibrils around the cell periphery. (nature.com)
  • These results show that mechanical stimulation directly affected FN reorganization and recruitment, despite perturbation by chemical stimulation. (nature.com)
  • Though most of these studies have probed these questions through chemical stimulation, mechanical stimulation has been shown to be extremely important. (nature.com)
  • Thus a thorough understanding of both mechanical and chemical stimulation separately, as well as coupled together, is integral to gain insight into FN synthesis, function and the effects of various pathology-induced abnormalities that can perturb this multi-functional protein. (nature.com)
  • Subsequently, MC3T3-E1 cells were cultured on the PDMS-g-PNIPAAm substrates under mechanical stimulation by cyclically stretching the substrates. (researchgate.net)
  • We will use genetic tools to knock out genes and study the response of these mutants to touch stimulation in comparison to WT with regards to gene expression, phosphorylation cascades and alteration in growth and development. (lu.se)
  • The reasons for this excessive inflammatory response are unclear. (medlineplus.gov)
  • These hydro-mechanical tests have been used to calibrate a numerical model based on the discretization of pellets and powder using Code_Bright FEM. (easychair.org)
  • To reinforce the materials so that they can bear substantial mechanical loads, a second polymer, poly(ethylene glycol) diacrylate, was added to the original blend. (sciencedaily.com)
  • PBF uses thermoplastic polymer materials and the manufactured parts have quite good mechanical properties. (sintef.no)
  • Researchers have developed soft yet durable materials that glow in response to mechanical stress, such as compression, stretching or twisting. (sciencedaily.com)
  • A team of researchers led by the University of California San Diego has developed soft yet durable materials that glow in response to mechanical stress, such as compression, stretching or twisting. (sciencedaily.com)
  • Modeling the mechanical response of chondrocytes to cyclic loading in unconfined compression. (cdc.gov)
  • When bone is subjected to mechanical load, areas of tension and compression are generated in different regions, resulting in bone deposition and resorption as part of the remodeling process 7-8 . (bvsalud.org)
  • Recent research works demonstrated that the interaction between the loads and the carrying structure's boundary which is related to the inertia of the load is an influential factor on the dynamic response of the structure. (scielo.br)
  • Understanding the dynamic response of half-space subjected to different surface loads is of considerable practical interest for scientists and engineers. (scielo.br)
  • Dynamic response of a half-space subjected to concentrated loads at the surface or inside the half-space which was investigated by Horace Lamb [1] is the first well-known work in this field. (scielo.br)
  • Due to the practical importance of the research in this area, a great number of research works have been accomplished on the response of half-space subjected to different types of loads. (scielo.br)
  • The present double-blind, randomized, placebo-controlled clinical trial intended to test whether ingestion of a natural combination medicine (Tr14 tablets) affects serum muscle damage and inflammatory immune response after downhill running. (hindawi.com)
  • The results of the current study indicate that Tr14 seems to limit exercise-induced muscle damage most likely via attenuation of both innate and adaptive immune responses. (hindawi.com)
  • Eccentric exercise like downhill running is a special exercise mode which is known to cause substantial muscle damage followed by a pronounced inflammatory response. (hindawi.com)
  • When these stresses happen, the battery needs to be able to withstand the damage. (tamu.edu)
  • The ideas involved are important not only from the point of view of modelling real electronic circuits but also because many complicated processes in biology, medicine and mechanical engineering are themselves modelled by electric circuits. (sheffield.ac.uk)
  • This presentation will summarize results from studies of the mechanical behaviour of parts made by PBF, using polyamide 12 materials and two different PBF processes. (sintef.no)
  • The results were used to study the excitation and propagation processes of stress waves, including the longitudinal wave, the transverse wave and Rayleigh-wave. (scielo.br)
  • These diverse materials may exhibit time-dependent structures under transient or out-of-equilibrium conditions resulting from for example self-assembly processes, phase transitions or in response to external fields, such as flow. (lu.se)
  • The internal distribution of stresses is also studied and discussed in relation with failure mechanisms. (aps.org)
  • Batteries and capacitors can fail through the different effects of internal and external mechanical stresses. (tamu.edu)
  • In this study, we investigated the effectiveness and relevant mechanism of ARBs in alleviating renal fibrosis, especially by focusing on biomechanical stress-induced epithelial to mesenchymal transition (EMT) of renal epithelial cells. (bvsalud.org)
  • Our in vivo and ex vivo experimental data suggest that losartan treatment, even at a low dose can effectively alleviate renal fibrosis in mouse UUO model, at least partly by inhibiting the biomechanical stress-induced EMT of renal epithelial cells. (bvsalud.org)
  • Mechanical stress on the joints, such as occurs in movement, may result in an excessive inflammatory response in people with psoriatic arthritis. (medlineplus.gov)
  • Due to the high vascular pressure endothelial cells of AVMs are exposed to mechanical stress. (researchgate.net)
  • In response to mechanical stress, VEGF gene and protein expression increased in patient AVM endothelial cells. (researchgate.net)
  • Bevacizumab inhibited circular network formation of endothelial AVM cells and lowered VEGF gene and protein expression, even though the cells were exposed to mechanical stress. (researchgate.net)
  • Overall, mechanical stress increases VEGF expression in the microenvironment of AVM cells. (researchgate.net)
  • The instrumented mechanical impact tester (IMIT) has eight load cells to report load response and then calculate energy as a result of the load. (nasa.gov)
  • Understanding the molecular mechanisms used by these cells to respond to stress will provide new drug targets for treating valvular disease. (drugdiscoverynews.com)
  • Lund University researchers find that individual blood stem cells (depicted as snowflakes in this image) express stress-related transcripts when subjected to experimental procedures involving cell incubation at elevated temperatures. (lu.se)
  • According to a recent study by researchers from the Lund Stem Cell Center at Lund University, published in Nature Aging, the genetic changes previously observed in aging blood stem cells could be linked to cell extraction stress rather than the aging process itself. (lu.se)
  • Suspecting that experimental procedures used during gene expression analysis might be influencing the results, they examined how stress-related genes behaved in cells collected under different conditions. (lu.se)
  • When we looked at our data, we noticed a pattern of stress-induced changes in gene activity, especially in cells exposed to higher temperatures during isolation," explains David Bryder, Professor of Molecular Hematology at Lund University, and research group leader at Lund Stem Cell Center. (lu.se)
  • We developed a biomimetic approach to separate and characterize slow quasi-static and fast vibrational stress signals acting on a whisker base in realistic exploratory phases, using experiments on both real and artificial whiskers. (frontiersin.org)
  • 16 ] compared the one-way cyclic triaxial behaviors of saturated clay under several stress paths with VCP and CCP. (hindawi.com)
  • In the SSL, we derive a (nonlinear) continuum free energy description of the system in terms of local displacement of the lamellar layers, and use this free energy to study the mechanical behaviors. (caltech.edu)
  • Accelerometers are piezoelectric devices, that is, the primary sensing element is a piezoelectric element constructed in such a way that when stressed by vibratory forces, a proportional electrical signal is produced. (pcb.com)
  • Dr. Steven R. Goodman, editor-in-chief of Experimental Biology & Medicine , added, "Lacerda and colleagues provide a proteomic and interactomic analysis of proteins and protein networks affected by mitral valve mechanical stretch and/or endothelium removal. (drugdiscoverynews.com)
  • The investigations on the response of bone tissue under different loading conditions are important from clinical and engineering points of view. (mdpi.com)
  • Findings from this study reveal that thermo-responsive elastomer, together with mechanical conditioning, can potentially be applied to prepare high-quality cell sheets for bone tissue engineering. (researchgate.net)
  • The study was a cross-sectional analysis of responses to the 2007 survey of the longitudinal, population-based American Migraine Prevalence and Prevention (AMPP) study. (medscape.com)
  • In this paper, the influence of nesfatin-1 administration on rat humerus mechanical properties was analyzed. (mdpi.com)
  • However, there are still challenges, e.g., when it comes to predictable and repeatable mechanical properties. (sintef.no)
  • Mechanical properties of parts made by PBF vs. parts made by injection moulding with the same powder. (sintef.no)
  • A comparison between the mechanical properties achieved by the conventional laser PBF process and the more recent Jet Fusion PBF process (technology from HP). (sintef.no)
  • The latter process gives somewhat better mechanical properties, but larger variation from part to part. (sintef.no)
  • Random fiber networks are structural elements in many biological and man-made materials and the prediction of their mechanical properties is desirable in many applications. (aps.org)
  • In order to investigate the effects of different cyclic stress paths on the evolution of dynamic mechanical properties of frozen silt clay, a series of cyclic triaxial tests with variation confining pressure (VCP) or constant confining pressure (CCP) were performed. (hindawi.com)
  • In this paper, the evolution features of the axial resilient modulus, damping ratios, and the shape of hysteresis loops with an increase in the number of load cycles under different dynamic stress paths are comprehensively studied. (hindawi.com)
  • The results show that the loading angle of cyclic stress path and the phase difference between cyclic axial stress and confining pressure are the main factors that remarkably affect the development characteristics of the resilient modulus and damping ratio. (hindawi.com)
  • Mechanosensitive channels are membrane proteins that gate in response to mechanical stress/tension. (rug.nl)
  • By doing in-vivo measurements in a hydroponic system, this study investigated the responses of unimpeded roots to local mechanical stress of their neighbouring roots. (slu.se)
  • In this study, the primary and seminal roots showed contrasting responses of root growth rate and root growth direction. (slu.se)
  • An exciting feature of these materials is their inherent simplicity -- they need no electronics, no external power source," said study senior author Shengqiang Cai, a professor of mechanical and aerospace engineering at the UC San Diego Jacobs School of Engineering. (sciencedaily.com)
  • The study found that VCP tests were more appropriate than CCP tests in the simulation of traffic loading conditions because the VCP stress paths can provide the coupling effects of the variable deviatoric stress and variable confining pressure. (hindawi.com)
  • The model has been developed to study local and global responses on wetting at constant volume, such as water mass transfer between powder and pellets, evolution of local degrees of saturation and porosities -inside pellets and powder-, and mean stress evolution in pellet and powder domains. (easychair.org)
  • Although mouse infection models have been extensively used to study the host response to Mycobacterium tuberculosis, their validity in revealing determinants of human tuberculosis (TB) resistance and disease progression has been heavily debated. (imperial.ac.uk)
  • A study of the loading characteristics of mechanical bolts (stiffness and capacity) installed in coal ribs at five underground coal mines. (cdc.gov)
  • Stress triaxiality affects the mechanical response of these specimens, and the results can be used to predict the performance of real parts, which often have stress triaxiality. (sintef.no)
  • This transition is induced by increasing the temperature (which affects DNA bending stress and packing defects) or by varying external ionic conditions (which affects DNA-DNA repulsive interactions and overall genome stress in the capsid). (lu.se)
  • In contrast to classical rheological studies, which can only probe bulk cubic phase solutions, our AFM-FS analysis allows probing the response of cubic membranes to deformations occurring at length and force scales similar to those found in biological interactions. (lu.se)
  • The combination of new time- and spatial-resolved experimental methods combined with computational and theoretical approaches is required to determine the complex nonlinear and time-varying response to deformations which is often also non-homogeneous. (lu.se)
  • The time resolution and robustness of the contact detection strategies based on either slow or fast stress signals are determined. (frontiersin.org)
  • Such measurements are however difficult in real conditions, since head/body movements and whisking produce complex stress signals. (frontiersin.org)
  • To determine quantitative exposure-response relations between work with highly elevated arms and supraspinatus tendinitis, shoulder pain with disability, and shoulder pain without disability. (bmj.com)
  • Quantitative exposure-response relations were established between current work with highly elevated arms and clinically verified shoulder disorders. (bmj.com)
  • 14- 16 We aimed to establish quantitative exposure-response relations between work with highly elevated arms and shoulder disorders. (bmj.com)
  • The experiments proved that the bone strength parameters measured under various mechanical loading conditions increased after the nesfatin-1 administration. (mdpi.com)
  • Triaxial low-temperature apparatus (MTS-810) was taken advantage of to simulating various cyclic stress paths by changing cyclic loading conditions of axial stress and confining pressure. (hindawi.com)
  • It is shown that the third instability always precedes the second one under controlled-stress conditions. (caltech.edu)
  • An understanding of the geologic and stress conditions which lead to roof falls is necessary to assess the risk of failure and to design roof reinforcement to improve stability. (cdc.gov)
  • We describe an uncharacteristic industrial hygiene and public health response that occurred under conditions of a national health emergency. (cdc.gov)
  • Spindle reorientation in response to mechanical stress is an emergent property of the spindle positioning mechanisms. (unige.ch)
  • According to contrastively analyzing the evolution of dynamic parameters and the shape features of hysteresis loops under various cyclic stress paths, it can be clearly discovered that the evolution of sample microstructure and the development of dynamic characteristics of frozen samples have obvious dependence on the cyclic stress path. (hindawi.com)
  • Effects of stress triaxiality on the mechanical response − studied by testing notched round bar specimens with different notch radii. (sintef.no)
  • An acute bout of physical exercise depending on duration and intensity is known to induce changes of the immune response of both the innate and the adaptive immune system. (hindawi.com)
  • A viscoplastic continuum approach, developed over recent years, has shown some ability to approximate steady flow and stress profiles in multiple inhomogeneous flow environments. (aps.org)
  • Steepest descent method was employed to obtain the approximate far-field displacements and stresses. (scielo.br)
  • Mechanically sensitive chemical groups termed mechanophores can be covalently linked into polymers in order to trigger specific chemical reactions upon mechanical loading. (aps.org)
  • Dynamic stresses of a half-space subjected to a moving wheel-type load prescribed on a finite patch were investigated by Dehestani et al [4]. (scielo.br)
  • The mixture presents multi-modal porosity features that significantly evolve during the hydro-mechanical paths. (easychair.org)
  • supports should have broad, smooth bearing surfaces, rather than narrow or localized contacts, to minimize the danger of stress concentrations. (chemicalprocessing.com)
  • SA mechanoreceptors respond to a steady applied stress while FA mechanoreceptors are triggered by rapid events. (frontiersin.org)
  • In addition, selected test results under constant volume hydration are presented to gain insight into the coupled hydro-mechanical response of the mixture. (easychair.org)
  • but for a (hypothetical) second-order transition, the mechanical instability appears first as the stress is increased. (caltech.edu)
  • Proper orientation of the mitotic spindle plays a crucial role in embryos, during tissue development, and in adults, where it functions to dissipate mechanical stress to maintain tissue integrity and homeostasis. (unige.ch)
  • Emergency response equipment and supplies are handed over to Khoy University of Medical Sciences at a donation ceremony. (who.int)
  • Photo credit: WHO/WHO Iran 9 November 2023, Tehran, Islamic Republic of Iran - WHO has donated vital medical equipment and supplies to enhance emergency response capacity in the wake of the early 2023 earthquake in Khoy, in the Iranian province of West Azerbaijan. (who.int)
  • This initiative has been made possible thanks to United Nations (UN) Central Emergency Response Fund (CERF) support. (who.int)
  • The project has an estimated 3440 direct beneficiaries, while an additional 150 000 people will indirectly benefit from the strengthened emergency response capacity in the region. (who.int)
  • DMA is also described as rheology of solids and also Dynamic Mechanical Thermal Analysis (DMTA) when combining the information with temperature response. (instron.com)
  • Their compact size gives them the advantage of faster response times and greater resistance to thermal shock and vibration. (omega.com)
  • The types of metal used to fabricate the sensor impact accuracy, measurement range, response time and resistance to environmental stressors such as vibration. (omega.com)
  • Vibration can cause mechanical stress in the wires of thermocouples and RTDs. (omega.com)