Respiratory morphine. Medical search. Frequent questions

Morphine in the fourth ventricle and subarachnoid space (10-50 µg in 50 µl) induced respiratory depression qualitatively similar to that obtained after i.v. injection (1 mg/kg). (aspetjournals.org)
Serious, life-threatening, or fatal respiratory depression may occur. (nih.gov)
Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death. (nih.gov)
and follow patients for signs and symptoms of respiratory depression and sedation. (nih.gov)
Two capsules (5 mg & 10 mg) of morphine sulfate extended-release 1 milliliter ampoule containing 10 mg of morphine Relative contraindications to morphine include: respiratory depression when appropriate equipment is not available. (wikipedia.org)
Adverse effects of opioids Common and short term Itchiness Nausea Vomiting Constipation Drowsiness Dry mouth Respiratory depression Itching Other Opioid dependence Dizziness Decreased sex drive Loss of appetite Impaired sexual function Decreased testosterone levels Depression Immunodeficiency Opioid-induced abnormal pain sensitivity Irregular menstruation Increased risk of falls Slowed breathing Hallucinations Like loperamide and other opioids, morphine acts on the myenteric plexus in the intestinal tract, reducing gut motility, causing constipation. (wikipedia.org)
Information in the boxed warning for all IR and ER/LA opioid pain medicines will be updated and reordered to elevate the importance of warnings concerning life-threatening respiratory depression, and risks associated with using opioid pain medicines in conjunction with benzodiazepines or other medicines that depress the central nervous system (CNS). (medlineplus.gov)
Those consequences can include respiratory depression (difficulty or lack of breathing), and low blood pressure. (in.gov)
The most serious adverse effects of morphine hydrochloride are bronchospasm, respiratory depression, bile tract spasms, hypersensitivity reactions and general asthenia up to syncope. (who.int)
Both anxiolytics and narcotics may cause respiratory depression, especially when they are used together. (ipas.org)
Heroin, similar to morphine and other narcotics, reduces the brain's responsiveness to changes in carbon dioxide levels and hypoxia, thus resulting in respiratory depression. (medscape.com)
A concern among clinicians is that benzodiazepines and opioids alone or in combination could cause adverse events, including respiratory depression, confusion, falls, and even premature death in patients with respiratory compromise. (bmj.com)
Injecting a patient with super-potent morphine could result in serious consequences including respiratory depression, coma, and death. (fda.gov)
This antagonism affects all opiate receptors and corrects respiratory depression owing to natural and synthetic narcotics. (medscape.com)
The diagnosis should be questioned if respiratory depression does not improve after administration of 10 mg. (medscape.com)
Serious, life-threatening, or fatal respiratory depression may occur with use of Nalbuphine Hydrochloride Injection, especially during initiation or following a dosage increase. (nih.gov)
To reduce the ‎risk of respiratory depression, proper dosing and titration of ‎‎Nalbuphine Hydrochloride Injection are essential [see WARNINGS ]. (nih.gov)
Nalbuphine hydrochloride may produce the same degree of respiratory depression as equianalgesic doses of morphine. (nih.gov)
However, Nalbuphine Hydrochloride Injection exhibits a ceiling effect such that increases in dose greater than 30 mg do not produce further respiratory depression in the absence of other CNS active medications affecting respiration. (nih.gov)
When administered following or concurrent with mµ agonist opioid analgesics (e.g., morphine, oxymorphone, fentanyl), nalbuphine hydrochloride may partially reverse or block opioid-induced respiratory depression from the mµ agonist analgesic. (nih.gov)
Nalbuphine produces respiratory depression by direct action on brain stem respiratory centers. (nih.gov)
The respiratory depression involves a reduction in the responsiveness of the brain stem respiratory centers to both increases in carbon dioxide tension and electrical stimulation. (nih.gov)
In man, morphine produces a variety of effects including analgesia, constipation from decreased gastrointestinal motility, suppression of the cough reflex, respiratory depression from reduced responsiveness of the respiratory centre to CO2, nausea and vomiting via stimulation of the CTZ, changes in mood including euphoria and dysphoria, sedation, mental clouding, and alterations of the endocrine and autonomic nervous systems. (rxmed.com)
CNS Depression: Morphine should be used only with caution and in reduced dosage during concomitant administration of other opioid analgesics, general anesthetics, phenothiazines and other tranquilizers, sedative-hypnotics, tricyclic antidepressants and other CNS depressants (including alcohol). (rxmed.com)
Respiratory depression, hypotension and profound sedation or coma may result. (rxmed.com)
Recent research has found that fentanyl causes clinically significant respiratory depression long before the person is sedated. (healthnews.com)
Follow up treatment with oral morphine remained effective in reducing the symptom of breathlessness and no patient showed signs of respiratory depression. (nih.gov)
High doses can cause positive drug screens and can cause respiratory depression - in one case an infant given poppy seeds stopped breathing. (postindependent.com)
At higher doses, oxycodone has most of the disadvantages of morphine including respiratory depression. (globalrph.com)
A case of respiratory depression in a child with ultrarapid CYP2D6 metabolism after tramadol. (pneumotox.com)
Tramadol overdose causes seizures and respiratory depression but serotonin toxicity appears unlikely. (pneumotox.com)
Tramadol-induced respiratory depression in a morbidly obese patient with normal renal function. (pneumotox.com)
Respiratory depression after intrathecal injection of tramadol with hyperbaric bupivacaine]. (pneumotox.com)
Respiratory depression following oral tramadol in a patient with impaired renal function. (pneumotox.com)
Their most significant adverse effect is respiratory depression and subsequent hypoxemia. (medscape.com)
receptors may cause respiratory depression and other undesired effects (e.g. nausea, vomiting, pruritus). (druglibrary.org)
and concern about potential adverse effects (AEs), including respiratory depression and addiction. (uspharmacist.com)
45 In an exploratory study, both tapentadol and oxycodone produced respiratory depression. (joomag.com)
58,59 however, fatalities due to respiratory depression have occurred 60 but none are reported with transdermal buprenorphine in a data analysis from US poison centres. (joomag.com)
Morphine can cause short-term adverse effects.The main effects of morphine are on the central nervous system and can include nausea, vomiting, drowsiness and respiratory depression. (fsai.ie)
Tramadol was originally thought to have a lower risk of constipation, respiratory depression, overdose, and addiction compared with other opioids, but CYP metabolic polymorphisms that will be described later in this review contribute to interesting phenotypic differences in the analgesic and side effect profile. (medscape.com)

Even clinicians using lighter sedation analgesia must be able to manage respiratory arrest, in the unlikely event that an unintentional overdose should occur. (ipas.org)
When administered every 12 hours, the sustained-release tablets provide equivalent analgesia to morphine oral solution given 4-hourly. (rxmed.com)
Neuraxial morphine is associated with lower pain scores, longer time to first rescue analgesia, reduced postpartum opioid consumption and less sedation following CD, compared to parenteral opioids, though the risk of pruritus and nausea may be higher. (asra.com)
Therefore a balance between analgesia and side-effects must be considered for each patient when deciding individual neuraxial morphine dosing strategies. (asra.com)
Immediately after tracheal extubation, analgesia, sedation, heart rate, respiratory rate, and arterial blood pressure were measured at predetermined intervals and every 60 min thereafter until the first rescue analgesic. (scielo.br)
Morphine tolerance refers to the gradual decrease in the potency of a drug following its long-term administration at a fixed dose and usually requires higher and higher doses to maintain the initial level of analgesia [ 2 ]. (hindawi.com)
Patients and methods: A prospective randomized clinical study done on 52 patients, they were divided equally into two groups: Group M (Morphine) received (0.1mg/kg), and Group F (Fentanyl) received (1ug/kg) on induction, and supplemented by effective rescue analgesia. (bvsalud.org)

However, opioids such as morphine have life-threatening consequences if overdosed. (in.gov)
This includes the administration of long-acting neuraxial opioids such as morphine, scheduled non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen, and rescue oral opioids for breakthrough pain. (asra.com)
61 Conclusions Over the last 30 years, a number of analgesics have been identified that have similar analgesic efficacy to typical strong opioids such as morphine, oxycodone and fentanyl but whose activity is not mediated exclusively by the mu receptor. (joomag.com)

Potentially serious side effects of morphine include decreased respiratory effort, vomiting, nausea, and low blood pressure. (wikipedia.org)
It is important also to remember that metoclopramide, prochlorperazine and a number of other drugs given for nausea or other gut disturbances are essentially the same drugs as the APs, and can cause tardive and respiratory dyskinesias as well as the other problems linked to these medicines. (rxisk.org)
In response to a request from the International Chemical Workers Union to evaluate symptoms of headache, nausea, and respiratory symptoms among workers, an investigation was begun of possible hazardous working conditions at the Penick Corporation (SIC-2833), Newark, New Jersey. (cdc.gov)

Using morphine with other medicines that can make you feel drowsy such as sleeping tablets (e.g. benzodiazepines), other pain relievers, antihistamines, antidepressants, antipsychotics, gabapentinoids (e.g. gabapentin and pregabalin), cannabis and alcohol may result in severe drowsiness, decreased awareness, breathing problems, coma and death. (mydr.com.au)
Common side effects of morphine include drowsiness, vomiting, and constipation. (wikipedia.org)

These highlights do not include all the information needed to use morphine sulfate extended-release tablets safely and effectively. (nih.gov)
See full prescribing information for morphine sulfate extended-release tablets. (nih.gov)
Morphine sulfate extended-release tablets expose users to risks of addiction, abuse, and misuse, which can lead to overdose and death. (nih.gov)
Instruct patients to swallow morphine sulfate extended-release tablets whole to avoid exposure to a potentially fatal dose of morphine. (nih.gov)
Accidental ingestion of morphine sulfate extended-release tablets, especially by children, can result in fatal overdose of morphine. (nih.gov)
Prolonged use of morphine sulfate extended-release tablets during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated. (nih.gov)
Morphine sulfate extended-release tablets are an opioid agonist indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. (nih.gov)
Because of the risks of addiction, abuse, and misuse with opioids, even at recommended doses, and because of the greater risks of overdose and death with extended-release opioid formulations, reserve morphine sulfate extended-release tablets for use in patients for whom alternative treatment options (e.g., non-opioid analgesics or immediate-release opioids) are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient management of pain. (nih.gov)
Morphine sulfate extended-release tablets are not indicated as an as-needed (prn) analgesic. (nih.gov)
Morphine sulfate extended-release tablets 100 mg and 200 mg tablets, a single dose greater than 60 mg, or a total daily dose greater than 120 mg, are only for use in patients in whom tolerance to an opioid of comparable potency has been established. (nih.gov)
Discuss availability of naloxone with the patient and caregiver and assess each patient's need for access to naloxone, both when initiating and renewing treatment with morphine sulfate extended-release tablets. (nih.gov)

DBL Morphine Sulfate Injection is a pain reliever that belongs to a group of medicines called opioid analgesics. (mydr.com.au)
Opioid analgesics, such as morphine, continue to be the mainstay for managing severe and chronic pain. (hindawi.com)

FDA recently inspected Pharmakon's facility following the company's voluntary recall of super-potent morphine sulfate 0.5 mg/ml preservative free in 0.9% sodium chloride, 1 ml syringe, CII, for intravenous use. (fda.gov)
55 Sublingual buprenorphine provides similar analgesic efficacy to intramuscular or intravenous morphine. (joomag.com)
Despite all these treatment efforts, the dyspnea progressed and chest radiograph findings worsened ( Figure 1 , panel D). Intravenous morphine was initiated to alleviate breathing difficulties from illness on day 14. (cdc.gov)
Is intravenous long-acting opioid (morphine) associated with more postoperative hypoxemia than short-acting opioid (fentanyl) after non-cardiac surgery? (bvsalud.org)
Objective: To compare between intravenous long-acting opioid (Morphine), and short-acting opioid (Fentanyl) regarding postoperative hypoxemia after non-cardiac surgery. (bvsalud.org)

Similar to morphine, heroin and its metabolites have mu, kappa, and delta receptor activity. (medscape.com)
In cell-based assays, TRV130 elicits robust G protein signaling, with potency and efficacy similar to morphine, but with far less β -arrestin recruitment and receptor internalization. (aspetjournals.org)
Fentanyl is a powerful synthetic drug that is similar to morphine and heroin, but is 50 to 100 times more potent. (cdc.gov)

Taking certain medications during your treatment with morphine injection may increase the risk that you will experience serious or life-threatening breathing problems, sedation, or coma. (medlineplus.gov)

Patients considered opioid-tolerant are those taking, for one week or longer, at least 60 mg of morphine per day, 25 mcg transdermal fentanyl per hour, 30 mg of oral oxycodone per day, 8 mg of oral hydromorphone per day, 25 mg oral oxymorphone per day, 60 mg oral hydrocodone per day, or an equianalgesic dose of another opioid. (nih.gov)
Fentanyl is a synthetic opioid that is 50 to 100 times more potent than morphine. (healthnews.com)
Fentanyl is a synthetic opioid drug that's up to 100 times more potent than morphine, so even tiny amounts can be deadly. (healthnews.com)
Fentanyl is a powerful opioid drug similar to but much more potent than morphine. (healthnews.com)
Fentanyl is especially dangerous because it's incredibly potent, up to 100 times more than morphine. (healthnews.com)
70 Poison Control Centre data showed that the 7-day transdermal patch had lower prescription-adjusted rates of intentional abuse and suspected suicidal intent than all typical opioids (morphine, oxycodone, oxymorphone, methadone and transdermal fentanyl) in the US. (joomag.com)
On the other side, fentanyl titration may cause less postoperative respiratory complications. (bvsalud.org)
When postoperative VAS score â ¥4 , patients in Group M received 5mg morphine as bolus ,and re-assess pain every 5 min to give another bolus ( the total allowed dose was 15mg/3-4h).For Group F 50ug fentanyl was given as a bolus ,and could be repeated (total allowed dose was 100 ug/1-2h. (bvsalud.org)
Le but de ce travail était d'évaluer la qualité de l'analgésie chez des parturientes ayant bénéficié d'une césarienne pratiquée sous rachianesthésie associant bupivacaïne, fentanyl et morphine. (bvsalud.org)
Les critères d'inclusion étaient: être opérée pour césarienne en chirurgie programmée ou en urgence relative, être sous rachianesthésie réalisée avec l'association bupivacaïne, fentanyl et morphine. (bvsalud.org)

This company produced morphine, codeine, synthetic and semisynthetic narcotics from the raw materials gum opium and poppy straw concentrate. (cdc.gov)

Opioids also had a dose response relation with mortality: lower dose opioids (≤30 mg oral morphine equivalents a day) were not associated with increased mortality (1.03, 0.84 to 1.26) in contrast with higher dose opioids (1.21, 1.02 to 1.44). (bmj.com)
With repeated regular dosing, oral morphine is about 1/3 as potent as when given by i.m. injection and rectal sustained-release suppositories have approximately 40% the potency of s.c. morphine. (rxmed.com)

It was developed in 1916 in Germany, as one of several new semi-synthetic opioids in an attempt to improve upon morphine, diacetylmorphine (heroin), and codeine. (treatment4addiction.com)
Poppy seeds contain some natural morphine and codeine and have been used for pain in European folk medicine. (postindependent.com)
In contrast, codeine and tramadol are prodrugs: codeine is metabolized into morphine, and the active metabolite of tramadol is O -desmethyltramadol (M1). (medscape.com)

FOR IMMEDIATE RELEASE -- St. Louis, MO - June 9, 2008 - ETHEX Corporation announced today that it has voluntarily recalled a single lot of morphine sulfate 60 mg extended release tablets (Lot No. 91762) due to a report of a tablet with twice the appropriate thickness. (in.gov)

In the setting of breathlessness at rest or on minimal exertion from conditions such as advanced cancer or end-stage cardiorespiratory diseases, regular, low-dose sustained-release morphine significantly reduces breathlessness safely, with its benefits maintained over time. (wikipedia.org)
Randomised trials have shown that oral sustained release morphine can relieve chronic refractory breathlessness. (bmj.com)

Morphine injection poses risks of abuse, misuse and addiction which can lead to overdose and death. (mydr.com.au)
Morphine overdose occurs when a person intentionally or accidentally takes too much of the medicine. (medlineplus.gov)

In mice and rats, TRV130 is potently analgesic while causing less gastrointestinal dysfunction and respiratory suppression than morphine at equianalgesic doses. (aspetjournals.org)

Morphine pharmacology in β -arrestin-2 knockout mice suggested that a ligand that promotes coupling of the μ -opioid receptor (MOR) to G proteins, but not β -arrestins, would result in higher analgesic efficacy, less gastrointestinal dysfunction, and less respiratory suppression than morphine. (aspetjournals.org)
Morphine tolerance counteracts analgesic efficacy and drives dose escalation. (hindawi.com)
The mechanisms underlying morphine tolerance remain disputed, which has prevented the development of therapies to maximize and sustain analgesic efficacy. (hindawi.com)

Data at this time suggest peripheral nerve blocks provide analgesic benefit in cases where intrathecal morphine cannot be utilized or as a rescue technique for refractory pain. (asra.com)

About 70 percent of morphine is used to make other opioids such as hydromorphone, oxymorphone, and heroin. (wikipedia.org)
Soon after its introduction, heroin was realized to be clearly as addictive as morphine, prompting the US government to institute measures to control its use. (medscape.com)
Heroin is a highly addictive semisynthetic opioid that is derived from morphine. (medscape.com)
It was hoped that a thebaine-derived drug would retain the analgesic effects of morphine and heroin with less dependence. (treatment4addiction.com)
To some extent this was achieved, as oxycodone does not have the same immediate effect as heroin or morphine nor does it last as long. (treatment4addiction.com)

Morphine is used primarily to treat both acute and chronic severe pain. (wikipedia.org)
Morphine is a highly potent opiate (narcotic) analgesic because it treats moderate to moderately severe chronic pain. (opiates.com)
98% of patients with end stage respiratory disease experience breathlessness, which persists at rest or on minimal exertion, despite optimal treatment of the underlying disease (chronic refractory breathlessness). (bmj.com)
Morphine is considered one of the most effective drugs for managing severe and chronic pain, but its potential for an overuse disorder must also be taken into consideration when deciding on an appropriate treatment plan. (caron.org)
Morphine tolerance is an adaptive process induced by chronic morphine that has been shown to result from complex alterations at the molecular level with μ opioid receptors (MORs), as well as at the synaptic, cellular, and circuit levels. (hindawi.com)
Thus, chronic administration of opioids modifies neuronal MOR function through a variety of mechanisms including receptor phosphorylation, signaling, multimerization, and trafficking, which may underlie tolerance to morphine. (hindawi.com)

Drug Dependence: As with other opioids, tolerance and physical dependence tend to develop upon repeated administration of morphine and there is potential for abuse of the drug and for development of strong psychological dependence. (rxmed.com)

Work-related respiratory diseases include both those that are uniquely caused by work, such as coal workers pneumoconiosis, and those that are caused by both work and non-work factors. (cdc.gov)

Morphine is a potent opioid drug derived from the opium poppy plant . (opiates.com)
Additionally, on February 16, 2016, FDA received reports of serious adverse events experienced by three infants associated with the use of the recalled super-potent morphine sulfate products from Pharmakon. (fda.gov)
Carfentanil is an incredible 10,000 times more potent than morphine. (healthnews.com)

Its analgesic potency is essentially equivalent to that of morphine on a milligram basis up to a dosage of approximately 30 mg. (nih.gov)

A missed dose of morphine can also cause adverse effects. (caron.org)
Pregnant women, infants, the elderly and those with weakened immune systems or impaired respiratory function are subgroups that are more sensitive to adverse effects of morphine. (fsai.ie)

Changes in heart and respiratory rates and arterial blood pressure during surgery were recorded along with the corresponding EtISO. (scielo.br)

Long-acting formulations of morphine are available as MS-Contin, Kadian, and other brand names as well as generically. (wikipedia.org)

The efficacy and safety profile of morphine hydrochloride is well established based on the extensive clinical experience in the treatment of severe and most severe pain. (who.int)

Drugs like morphine and opium also have the same physical effects as oxycodone. (treatment4addiction.com)
Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system) is found to be associated with 2,580 drugs and 2,467 conditions by eHealthMe. (ehealthme.com)
These drugs however can also cause a respiratory dyskinesia that may be mistaken for asthma or other lung conditions and lead to inappropriate treatment. (rxisk.org)
Opioid drugs, such as morphine and meperidine, are pregnancy category C medications, which means they can be used but they cross the placental barrier. (medscape.com)

Corticosteroids were added after the appearance of progressive hypoxemia and acute respiratory distress syndrome. (cdc.gov)

Extended-release Morphine tablets are only used by patients who require around the clock pain relief, while the short-acting formulation is taken as needed. (opiates.com)
Oversized tablets may contain as much as two times the labeled level of active morphine sulfate. (in.gov)
Such tablets may contain as much as twice the labeled level of active morphine ingredient. (in.gov)
Vendal retard 30 mg- film-coated tablets is a prolonged released formulation containing morphine hydrochloride. (who.int)
Elderly Man Force Fed Morphine Tablets And Treated. (davidicke.com)
The sustained-release suppositories given 12-hourly provide equivalent pain control to the sustained-release tablets given orally at the same dose and frequency, or to morphine administered s.c. at a dose approximately 40% of the daily rectal dose. (rxmed.com)
At steady-state, the sustained-release tablets produce peak morphine levels approximately 4 to 5 hours post-dose and therapeutic levels persist for a 12-hourly period. (rxmed.com)
The extent of absorption of sustained-release suppositories at steady-state is equivalent to that of the sustained-release tablets and approximately 40% of that of s.c. morphine. (rxmed.com)

DBL Morphine Sulfate Injection is used most commonly for short-term relief of severe pain. (mydr.com.au)
Drug abuse is not a problem in patients with severe pain in which morphine is appropriately indicated. (rxmed.com)
Morphine is an opioid medication used for moderate to severe pain relief . (caron.org)

The cough syrup's label contains information in both Chinese and English, but the English portion of the label does not identify the presence of the pain reliever morphine. (yourlawyer.com)

Conclusions Lower dose opioids are not associated with increased admissions or deaths in patients with COPD and might be safe for symptom reduction in severe respiratory disease. (bmj.com)

Oxycodone can produce drug dependence of the morphine type and, therefore, has the potential for being abused. (globalrph.com)
Tapentadol 100mg (but not 150mg) had a modest respiratory advantage over oxycodone 20mg. (joomag.com)

Morphine injection should only be used when your doctor decides that other treatment options are not able to effectively manage your pain or you cannot tolerate them. (mydr.com.au)
This leaflet provides important information about using DBL Morphine Sulfate Injection. (mydr.com.au)
You should also speak to your doctor or pharmacist if you would like further information or if you have any concerns or questions about using DBL Morphine Sulfate Injection. (mydr.com.au)
1. Why am I being treated with DBL Morphine Sulfate Injection? (mydr.com.au)
DBL Morphine Sulfate Injection contains the active ingredient morphine sulfate pentahydrate. (mydr.com.au)
2. What should I know before treatment with DBL Morphine Sulfate Injection? (mydr.com.au)
If you have not told your doctor or pharmacist about any of the above, tell them before you are given DBL Morphine Sulfate Injection. (mydr.com.au)
Morphine injection may be habit forming, especially with prolonged use. (medlineplus.gov)
Use morphine injection exactly as directed. (medlineplus.gov)
Your doctor will probably tell you not to use morphine injection. (medlineplus.gov)
Morphine is readily absorbed when given orally, rectally or by s.c. or i.m. injection. (rxmed.com)

Morphine is a strong opiate that is found naturally in opium, a dark brown resin produced by drying the latex of opium poppies (Papaver somniferum). (wikipedia.org)
Morphine is also available as a slow-release formulation for opiate substitution therapy (OST) in Austria, Germany, Bulgaria, Slovenia, and Canada for persons with opioid addiction who cannot tolerate either methadone or buprenorphine. (wikipedia.org)
Morphine is a fast-acting opiate analgesic and the primary agent in opium. (opiates.com)

Withdrawal symptoms may occur following abrupt discontinuation of morphine therapy or upon administration of an opioid antagonist. (rxmed.com)

Morphine use can lead to physical dependence, even when taken as prescribed by a doctor because of the way it works in the brain. (caron.org)

Morphine was slightly more effective in the subarachnoid space than in the fourth ventricle. (aspetjournals.org)

Furthermore, reports by the National Institute of Drug Addiction (NIDA) show that morphine acts by attaching to the opioid receptors located in the brain, spinal cord, and gastrointestinal tract. (opiates.com)

Morphine has been used medically since the early 19th century and is still one of the most commonly prescribed pain medications today. (caron.org)
Morphine dependency can be effectively treated with a combination of medications, counseling, and other supportive therapies. (caron.org)
None of the individuals should use bronchodilator therapy or medications that directly act on the respiratory system. (who.int)

9. Marucio RL, Luna SP, Neto FJ, Minto BW, Hatschbach E. Postoperative analgesic effects of epidural administration of neostigmine alone or in combination with morphine in ovariohysterectomized dogs. (scielo.br)

The primary source of morphine is isolation from poppy straw of the opium poppy. (wikipedia.org)

are allergic to any medicine containing morphine, any of the ingredients listed at the end of this leaflet, or any other similar medicines. (mydr.com.au)
A consumer who is hypersensitive to morphine could suffer a severe allergic reaction if he or she uses Licorice Coughing Liquid. (yourlawyer.com)

A 2016 Cochrane review concluded that morphine is effective in relieving cancer pain. (wikipedia.org)

Anatomy3

Organisms2

Diseases7

Chemicals and Drugs35

Analytical, Diagnostic and Therapeutic Techniques and Equipment9

Psychiatry and Psychology5

Phenomena and Processes5

Health Care1

Depression41

Analgesia7

Opioids such as morphine3

Nausea3

Drowsiness2

Sulfate extended-release11

Analgesics2

Intravenous5

Similar to morphine3

Treatment with morphine1

Fentanyl10

Narcotics1

Oral morphine2

Codeine3

Extended-release tablets1

Sustained-release morphine2

Overdose2

Equianalgesic doses1

Analgesic efficacy3

Intrathecal1

Heroin5

Chronic6

Administration of morphine1

Diseases1

Potent3

Potency1

Adverse effects2

Heart and respiratory rates1

Kadian1

Efficacy1

Drugs4

Hypoxemia1

Tablets8

Severe pain3

Pain reliever1

Dose opioids1

Oxycodone2

Injection11

Opiate3

Symptoms1

Dependence1

Fourth ventricle1

Addiction1

Medications3

Epidural administration1

Opium1

Allergic2

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