• Human thyroid peroxidase: complete protein sequence, chromosome mapping, and identification two alternately spliced mRNAs. (rusmedserv.com)
  • Regional localization of the thyroid peroxidase to human chromosome 2pter-p12. (rusmedserv.com)
  • Elisei R, Vassart G, Ludgate M. Demonstration of the alternatively spliced form of thyroid peroxidase normal thyroid. (rusmedserv.com)
  • Human thyroid peroxidase (TPO) isoforms, and TPO-2: analysis of protein expression in Graves' tissue. (rusmedserv.com)
  • Isolation and characterization of a cDNA clone for porcine thyroid peroxidase. (rusmedserv.com)
  • Derwahl M, Seto P, Rapoport B. Complete nucleotide sequence of the cDNA for thyroid peroxidase in FRTL5 rat thyroid cells. (rusmedserv.com)
  • Nucleotide sequence of the cDNA encoding mouse thyroid peroxidase. (rusmedserv.com)
  • Rawitch AB , Pollock G, Yang SX, Taurog A. Thyroid peroxidase glycosylation: the location and nature of the N-linked oligosaccharide units in porcine thyroid peroxidase. (rusmedserv.com)
  • Identification of an immunodominant region recognized by human autoantibodies in a three-dimensional model of thyroid peroxidase. (rusmedserv.com)
  • Thyroid peroxidase (EC 1.11.1.8 ) (TPO). (expasy.org)
  • Our objective was to compare the frequency of thyroid peroxidase antibody (anti-TPO) in vitiligo patients with healthy subjects in Iran. (biomedcentral.com)
  • Cytochromes P450, thyroid peroxidase, and dihydrolipolyllysine-residue succinyltransferase: Research in protein structure and function. (missouristate.edu)
  • Iodotyrosine is made from tyrosine via thyroid peroxidase and then further iodinated by this enzyme to make the di-iodo an tri-iodo variants. (speciation.net)
  • Efforts to modulate this exchange behaviour through the application of putative TPx ligands and chemical modification of the active site cysteine residues are described. (ndltd.org)
  • The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. (nih.gov)
  • The transcription of COX-1 yields a 2.7-kilobase (kb) messenger ribonucleic acid (mRNA) that encodes a 576-residue, 65-kd protein. (medscape.com)
  • Because galactose oxidase-mediated oxidation liberates a molecule of hydrogen peroxide for each molecule of aldehyde that is formed ( Figure 3.3.2 ), horseradish peroxidase-catalyzed oxidation of the Amplex Red reagent to red-fluorescent resorufin by hydrogen peroxide provides a ready means by which the number of aldehyde residues introduced into a biomolecule, including on a cell surface, can be quantitated. (thermofisher.com)
  • An other histidine residue (the distal histidine) serves as an acid-base catalyst in the reaction between hydrogen peroxide and the enzyme. (expasy.org)
  • Figure 3.3.1 Sodium periodate oxidation of an N-terminal serine residue to an aldehyde, with the release of formaldehyde. (thermofisher.com)
  • The tentative determinant for discriminating between the two binding modes is the position of the O6 hydroxyl group, which in the C2-oxidation mode can make favorable interactions with Asp452 in the substrate loop and, possibly, a nearby arginine residue (Arg472). (nih.gov)
  • These two Prdx6's have only 8% difference in their primary sequence (with 19 amino acids) with no apparent modification at any of the key conserved residues. (jascoinc.com)
  • Cloning and sequence analysis of the human salivary peroxidase-encoding cDNA. (rusmedserv.com)
  • For each profile, the multiple sequence alignments contain annotations of residues conserved in the whole family, plus residues specific to the subfamily. (inra.fr)
  • Molecular docking analysis for different enzymes involved in aging (collagenase, elastase and hyaluronidase), antioxidant enzymes (superoxide dismutase, glutathione-s-transferase, glutathione peroxidase and catalase) and mitochondrial enzymes (nicotinamide adenine dinucleotide (NAD)+hydrogen (H) dehydrogenase, succinate dehydrogenase, cytochrome c oxidase and adenosine triphosphate synthase) was carried out for epigallocatechin gallate alone (1), withaferin A alone (2), epigallocatechin gallate and withaferin A in combination (3) and a reference molecule. (ijpsonline.com)
  • Lignin peroxidase (LiP), which has been studied extensively in white-rot Basidiomycetes with regard to bio-pulping and bio-bleaching, plays a role in the biodegradation of plant cell wall lignin. (ncsu.edu)
  • Some of them play a role in cell-suberization by catalyzing the deposition of the aromatic residues of suberin on the cell wall, some are expressed as a defense response toward wounding, others are involved in the metabolism of auxin and the biosynthesis of lignin. (expasy.org)
  • Pyranose 2-oxidase (P2Ox) participates in fungal lignin degradation by producing the H2O2 needed for lignin-degrading peroxidases. (nih.gov)
  • The application of enzymes for waste treatment has been gaining pace commercially to solve concerns related to agricultural residues, wastewater, replacement of synthetic processes with natural ones, etc. (preprints.org)
  • Kimura S, Ikeda-Saito M. Human myeloperoxidase peroxidase, two enzymes with separate and distinct physiological functions, are evolutionary related members gene family. (rusmedserv.com)
  • Some bacterial species produce enzymes that exhibit both catalase and broad-spectrum peroxidase activities [4]. (expasy.org)
  • The major aspect of work describes the characterization by NMR of the Mtb thiol peroxidase TPx. (ndltd.org)
  • We also developed two profiles, one specific for the animal peroxidases superfamily and one directed against the plant peroxidase superfamily. (expasy.org)
  • Here, we report the X-ray structure of Thermobifida fusca AA10A (TfAA10A), investigate mutational characterization of key surface residues near its active site, and explore the importance of the various domains of Thermobifida fusca AA10B (TfAA10B). (biomedcentral.com)
  • Colorimetric and chemiluminescent dual-readout immunochromatographic assay for detection of pesticide residues utilizing g-C3N4/BiFeO3 nanocomposites. (cdc.gov)
  • Based on the catalytical activity on the luminol-H2O2 reaction, the nanocomposites were utilized as a colorimetric/chemiluminescent dual-readout immunochromatographic assay (ICA) for the multiplexed detection of pesticide residues by utilizing chlorpyrifos and carbaryl as the model analytes. (cdc.gov)
  • A monoclonal mouse anti-peroxidase antibody is a very useful and reliable reagent for the localization of a number of mouse primary antibodies by peroxidase anti-peroxidase (PAP) immunocytochemistry. (medimabs.com)
  • If the streptomycin residue is present in the sample, it will compete for the streptomycin antibody, thereby preventing the streptomycin-HRP from binding to the antibody attached to the well. (elisatest-kits.com)
  • A novel cDNA encoding glutathione peroxidase of tea plant (Camellia sinensis) was isolated by rapid amplification of cDNA ends (RACE) method and designated as CsGPX2 (GenBank Accession No. JQ247186). (springeropen.com)
  • Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. (thermofisher.com)
  • Their distinct biosynthetic activity includes an endoperoxidase synthase reaction that oxygenates and cyclizes polyunsaturated fatty acid precursors (eg, arachidonic acid) to form prostaglandin G 2 (PGG2), and a peroxidase reaction that converts PGG2 to prostaglandin H 2 (PGH2), as shown below. (medscape.com)
  • Peroxidases catalyze a wide variety of peroxide-dependent oxidations. (rcsb.org)
  • TPx (165 residues) is a 36 kD symmetrical homodimer that catalyzes the reduction of a range of reactive oxygen species in vitro. (ndltd.org)
  • In previous structures of P2Ox, the substrate loop (residues 452-457) covering the active site has been either disordered or in a conformation incompatible with carbohydrate binding. (nih.gov)
  • Graphitic carbon nitride/bismuth ferrite nanocomposites (g-C3N4/BiFeO3 NCs) were synthesized by a facile one step sol-gel combustion method and employed as a peroxidase-like catalyst. (cdc.gov)
  • Galactose oxidase oxidizes terminal galactose residues to aldehydes, particularly in glycoproteins. (thermofisher.com)
  • In order to make the profiles more specific, residues that are conserved in the whole family are lightened and residues specific to each subfamily are emphasized. (inra.fr)
  • Our study revealed that human and rat Prdx6's exhibit differences in their peroxidase activity. (jascoinc.com)
  • Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. (thermofisher.com)
  • 2,3,7,8-Tetrachlorodibenzo- p -dioxin as an antiestrogen: Effect on rat uterine peroxidase activity. (cdc.gov)
  • The resulting color intensity, after addition of the HRP substrate (TMB), has an inverse relationship with the streptomycin residue concentration in the sample. (elisatest-kits.com)
  • The introduction of galactose residues can be especially advantageous for structural studies because it provides a means of selectively labeling specific sites on biomolecules. (thermofisher.com)
  • Marti, D. N. & Bosshard, H. R. Electrostatic interactions in leucine zippers: thermodynamic analysis of the contributions of Glu and His residues and the effect of mutating salt bridges. (uzh.ch)