• researchers
  • The reserpine-induced depression is considered by some researchers to be a myth, while others claim that teas made out of the plant roots containing reserpine have a calming, sedative action that can actually be considered antidepressant. (wikipedia.org)
  • drug
  • Some reserpine molecules do seem to escape metabolism, however, since significant amounts of intact reserpine have been found in fecal samples taken from both experimental animals and human beings after either oral or parenteral drug administration. (aspetjournals.org)
  • Syrosingopine is a drug, derived from reserpine. (wikipedia.org)
  • Tranquilizer, as a term, was brought into existence by F.F. Yonkman (1953), from the conclusions of investigative studies using the drug Reserpine, showed the drug had a calming effect on all animals it was administered to. (wikipedia.org)
  • injection
  • During this time a relatively small fraction of the total reserpine administered by injection would become associated with monoaminergic granular membranes in a more specific and irreversible manner. (aspetjournals.org)
  • tract
  • Orally administered reserpine is readily absorbed from the GI tract. (aspetjournals.org)
  • Since most of the blood leaving the GI tract passes through the liver via the portal vein, hepatic metabolism would also be expected to reduce reserpine levels in the blood. (aspetjournals.org)
  • known
  • The relative contributions of serum esterases versus hepatic metabolism in the biotransformation of reserpine in vivo are not known. (aspetjournals.org)
  • tell your doctor
  • tell your doctor and pharmacist if you are allergic to reserpine, aspirin, any other medications, tartrazine (a yellow dye in some processed foods and medications), or any of the ingredients in reserpine tablets. (medlineplus.gov)
  • patients
  • In 1987, reserpine was considered a second-line adjunct agent for patients who were uncontrolled on a diuretic alone when cost was an issue. (wikipedia.org)
  • properties
  • Because of its lipophilic properties, reserpine would easily penetrate cell membranes and then bind possibly electrostatically to intracellular membrane components, particularly those rich in phospholipids. (aspetjournals.org)