Researchers cells hair. Medical search. Frequent questions

hair-inducing potential in mice. (lifecoderx.com)
Though more studies are needed before a "stem cell cure for baldness" is ready for humans, researchers are reporting success in using such treatments on laboratory mice. (miamihair.com)
Following transplant to laboratory mice, the HSPCs grew new hair, giving researchers hope that the same process could one day be replicated with humans. (miamihair.com)
This is happening in natural killer cells, T cells, dendritic cells from human skin, and epidermal stem cells in mice," says Samantha B. Larsen, a former graduate student in the laboratory of Elaine Fuchs at The Rockefeller University. (scitechdaily.com)
So the Fuchs lab once again exposed mice skin to irritants, and watched as stem cells in the skin changed. (scitechdaily.com)
For years, scientists have thought that these cells are not replaced once they're lost, but new research appearing online February 20 in the journal Stem Cell Reports reveals that supporting cells in the ear can turn into hair cells in newborn mice. (science20.com)
The team's previous research revealed that inhibition of the Notch signaling pathway increases hair cell differentiation and can help restore hearing to mice with noise-induced deafness. (science20.com)
In the study, to be published online May 4 in Nature Medicine , the researchers used sophisticated techniques to pin down numerous important molecular, neuroanatomical and neurophysiological changes in the brains of old mice that shared the blood of young mice. (sciencedaily.com)
The scientists simply compared older mice's performance on standard laboratory tests of spatial memory after these mice had received infusions of plasma (the cell-free part of blood) from young versus old mice, or no plasma at all. (sciencedaily.com)
Previous experiments by Wyss-Coray, Villeda and their colleagues, described in a paper published in 2011 in Nature , had revealed that key regions in the brains of old mice exposed to blood from young mice produced more new nerve cells than did the brains of old mice similarly exposed to blood from old mice. (sciencedaily.com)
Conversely, exposing young mice to blood from old mice had the opposite effect with respect to new nerve-cell production, and also reduced the young mice's ability to navigate their environments. (sciencedaily.com)
When the investigators compared hippocampi from old mice whose circulatory systems had been conjoined with those of young mice to hippocampi from old mice that had been paired with other old mice, they found consistent differences in a number of biochemical, anatomical and electrophysiological measures known to be important to nerve-cell circuits' encoding of new experiences for retention in the cerebral cortex. (sciencedaily.com)
The technique works with near-perfect efficiency in mice and humans for all types of cells tested in the laboratories of USC's stem cell center. (usc.edu)
To explore this potential origin of melanoma, a team of researchers led by Dr. Mayumi Ito at NYU Langone Health genetically engineered mice with oncogenic gene mutations in the melanocyte stem cells within hair follicles. (nih.gov)
The researchers found that melanomas from these genetically modified mice share similar genetic and molecular characteristics with human melanomas. (nih.gov)
As reported in a Penn news release , Xiaowei "George" Xu, MD, PhD, associate professor of Pathology and Laboratory Medicine and Dermatology at the Perelman School of Medicine, University of Pennsylvania, and colleagues published in Nature Communications a method for converting adult cells into epithelial stem cells (EpSCs), the first time anyone has achieved this in either humans or mice. (scienceblog.com)
The epithelial stem cells, when implanted into immunocompromised mice, regenerated the different cell types of human skin and hair follicles, and even produced structurally recognizable hair shaft, raising the possibility that they may eventually enable hair regeneration in people. (scienceblog.com)
When they mixed those cells with mouse follicular inductive dermal cells and grafted them onto the skin of immunodeficient mice, they produced functional human epidermis (the outermost layers of skin cells) and follicles structurally similar to human hair follicles. (scienceblog.com)
The study, which appears in the early online edition of the Proceedings of the National Academy of Sciences (PNAS), found that mice lost 85 percent of their hair if they received radiation therapy in the morning, compared to a 17 percent loss when treatment occurred in the evening. (scienceblog.com)
We found that hair in mice grows fast in the morning and slows down at night, engaging a very powerful clock. (scienceblog.com)
The scientists discovered that mice hair cells repair that damage primarily in the evening. (scienceblog.com)
While we don't yet know if human hair follows that same clock we found in mice hair, it is true that facial hair in men grows during the day, resulting in the proverbial 5 o'clock shadow. (scienceblog.com)
Japanese researchers have found that a specific type of collagen is responsible for damaging hair follicle stem cells in mice, leading to hair loss, and think the same mechanism is responsible for hair loss in people. (japantimes.co.jp)
The phenomenon was observed in the skin of mice that were 18 months old, the age at which hair loss in mice begins. (japantimes.co.jp)
The researchers found that older mice had fewer, thinner follicles than younger mice. (japantimes.co.jp)
In mice lacking type XVII collagen, damaged stem cells turned themselves into skin cells and sloughed off from the scalp as scurf, resulting in hair loss. (japantimes.co.jp)
Mice that continued to produce the collagen were found to be less prone to hair loss despite aging. (japantimes.co.jp)
A new study in mice shows that these melanocyte stem cells migrate between two sites in the hair follicle during each cycle of hair growth and shedding- from a site where they produce the pigment for hair color to another where they produce stem cells. (medicalnewstoday.com)
Researchers analyzed inner ear tissue sourced from humans and mice to create in-vitro cellular models of the inner ear. (healthline.com)
Next, the researchers create bald spots on the mice using a hair removal cream. (bgr.com)
Researchers noticed more change in the mice with the specialized patches than those with control patches. (bgr.com)
These mice showed faster signs of the hair undergoing a transition. (bgr.com)
Furthermore, mice with the specialized patches had faster hair regrowth than those using a leading topical treatment. (bgr.com)
Hair growth was arrested and the mice became bald when the KROX20-producing cells were deleted. (news-medical.net)
Researchers Adam Cohen (left) and Yoav Adam have found a way to watch a live broadcast of neurons firing in real time - with mice. (harvard.edu)

By understanding this, scientists will be better positioned to develop new ways to battle hearing loss - even the kind that comes from aging, the researchers say. (news-medical.net)
Hearing loss due to aging, noise, and certain cancer therapy drugs and antibiotics has been irreversible because scientists have not been able to reprogram existing cells to develop into the outer and inner ear sensory cells - essential for hearing - once they die. (hearingreview.com)
But Northwestern Medicine scientists have discovered a single master gene that programs ear hair cells into either outer or inner ones, overcoming a major hurdle that had prevented the development of these cells to restore hearing, according to new research published in Nature . (hearingreview.com)
Currently, scientists can produce an artificial hair cell, but it does not differentiate into an inner or outer cell, which provide different essential functions to produce hearing. (hearingreview.com)
The master gene switch Northwestern scientists discovered that programs the ear hair cells is TBX2 . (hearingreview.com)
Scientists have long suspected that even cells that are not traditionally involved in the immune response have the rudimentary ability to remember prior insults and learn from experience. (scitechdaily.com)
Combining this new knowledge about Lgr5-expressing cells with the previous finding that Notch inhibition can regenerate hair cells will allow the scientists to design new hair cell regeneration strategies to treat hearing loss and deafness. (science20.com)
USC scientists have found a solution to untangle twisty DNA, removing kinks so the molecules can be used to reprogram cells to advance regenerative medicine to treat disease. (usc.edu)
USC scientists have surmounted a big roadblock in regenerative medicine that has so far constrained the ability to use repurposed cells to treat diseases. (usc.edu)
Cellular reprogramming has enormous potential as a disease cure because it enables scientists to study cells and molecular processes at each step of disease progression in controlled conditions that have, until now, been impossible. (usc.edu)
For 12 years, scientists worldwide have struggled with conflicting brain-scanning results on how ecstasy might harm brain cells that use serotonin. (maps.org)
A team of researchers, including Japanese scientists, has discovered the mechanism behind hair loss associated with aging, a finding that could pave the way for new ways to treat baldness. (japantimes.co.jp)
A team of scientists have discovered that stem cell-derived neurons from combat veterans with post-traumatic stress disorder (PTSD) react differently. (scienceboard.net)
As a first step in creating such replacement skin, scientists in Cincinnati have engineered bacteria-resistant skin cells in the lab and are now testing them in animals. (technologyreview.com)
More recently, scientists have begun seeding the collagen scaffolds with skin cells to help the skin grow: rather than transplanting epidermis onto newly grown skin, scientists grow epidermis cells on the collagen scaffold and then transplant the entire sheet. (technologyreview.com)
According to a new study , scientists were able to regrow hair on a mouse much faster than leading treatments. (bgr.com)
If scientists could give living cells magnetic properties, they could perhaps manipulate cellular activities with external magnetic fields. (acs.org)
Scientists aspire to utilize stem cell transplantation for pediatric patients grappling with blood-related conditions like aplastic anemia, and thalassemia. (medindia.net)
Recently, scientists estimated the cell volume of a marine bacterium at 0.013 cubic microns, but they used a technique that did not directly measure the cell diameter. (ibtimes.com)
Providing specimens may help scientists better understand the cause(s) of ALS by providing researchers with access to ALS biological samples. (cdc.gov)
Some scientists thought these animals might have longer lifespans due to their slower metabolic rates and lower energy demands, resulting in less damage to their cells and tissues and a slower aging process. (medlineplus.gov)

And isn't limited by the availability of existing hair follicles [donor hair]. (miamihair.com)

But neural crest cells transiently arise from the dorsal neural tube during development, and give rise to many tissues at that time, including hair follicle cells. (lifecoderx.com)

During the consultation, we will perform an in-depth scalp examination, review your family hair history, discuss your expectations and provide an honest evaluation of your situation. (miamihair.com)
Hypohidrotic ectodermal dysplasia is characterized by a reduced ability to sweat (hypohidrosis), sparse scalp and body hair (hypotrichosis), and several missing teeth (hypodontia) or teeth that are malformed. (medlineplus.gov)
In the study led by Tokyo Medical and Dental University's Emi Nishimura, the team determined that type XVII collagen, found near hair follicle stem cells beneath the scalp, is the key to thinning hair. (japantimes.co.jp)
In a separate analysis of the human scalp, the researchers discovered that hair follicles in women in their 50s or older had shrunk more than hair follicles in women in their 30s and 40s. (japantimes.co.jp)
Hair transplants, which include extracting follicles from DHT-resistant "donor regions" at the sides and back of the scalp and relocating them to cover bald spots, have been a new source of hope for people experiencing hair loss throughout the past two decades. (the-psa.co.uk)
To then be transplanted into the scalp to create new hair. (the-psa.co.uk)
Hair regenerative medicine can potentially increase the number of hairs on the scalp, which is something that traditional hair transplantation cannot do. (the-psa.co.uk)
Essentially, it's a permanent condition that causes the cells in the scalp to die, making them unable to grow new hair. (bgr.com)
Combine that with a lack of accumulation of reactive oxygen in the scalp, and the cells start to die. (bgr.com)

Tbx2 is a master regulator of inner versus outer hair cell differentiation. (hearingreview.com)
Overall, the group reported, ?our results suggest that the intermediate step of hESC differentiation into the NC [neural crest] lineage seems critical, skipping the NC induction results in a complete loss of hair-inducing activity. (lifecoderx.com)
Resulting cultures become ?enriched in hair-inducing DP-like cells using relatively common mesenchymal-enriching conditions, such as differentiation in serum containing medium and selection for the adherent cell types. (lifecoderx.com)
Desmosomes may also be involved in other critical cell functions, including chemical signaling pathways, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). (medlineplus.gov)
November 4, 2022 -- Researchers have discovered a novel pathway very early during in vitro differentiation that supports the development of T cells and natural killer (NK) cells from human induced pluripotent stem cells (iPSCs). (scienceboard.net)
This differentiation of stem cells to a cell type that performs a specific function is thought to be irreversible. (medicalnewstoday.com)
Within the tooth bud created by this process, a differentiation of various cell types occurs: the enamel organ, the dental papilla, and the dental lamina. (bionity.com)
Stimulation of this receptor with norepinephrine or a synthetic specific α2A receptor agonist promotes epithelial proliferation and stem cell function, while reducing differentiation in vivo and in intestinal organoids. (bvsalud.org)

For many years, auditory research has placed considerable emphasis on the regeneration of sensory hair cells. (news-medical.net)
If we ever want to prevent hair loss from happening or resurrect hair growth once you start to lose your hair, we need to focus on maintaining the function of these hair follicle dermal stem cells," says Biernaskie, associate professor of comparative biology and experimental medicine at UCVM, and the Calgary Firefighters Burn Treatment Society Chair in Skin Regeneration and Wound Healing. (ucalgary.ca)
As well as helping shift the direction of research into hair loss, the findings have wider implications for understanding healthy aging, skin regeneration, and wound healing. (ucalgary.ca)
This is a strategy for greatly improving our ability to perform cellular reprogramming, which could enable the regeneration of lost tissues and the study of diseases that cannot be biopsied from living patients today," said Justin Ichida , PhD, assistant professor in the department of stem cell biology and regenerative medicine at the Keck School of Medicine of USC . (usc.edu)
Hair cell regeneration was not a major topic of research in hearing science until 1986-87. (hearingreview.com)
Hair cell regeneration occurring after hair cells were destroyed. (hearingreview.com)
We and others are working hard to understand the molecular chain of events responsible for hair cell regeneration in species where it occurs. (hearingreview.com)
We have also discovered one gene (and there will be others) that is responsible for turning off the production of hair cells during development and may be involved in preventing regeneration. (hearingreview.com)
In fact, a team of researchers has recently used new findings from research on development of the inner ear to induce a few new cells in the guinea pig cochlea to become hair cells again proving that hair cell regeneration will be possible. (hearingreview.com)
The good news is that, for the first time in history, there are teams of investigators worldwide exploring the possibility that hair cell regeneration can be induced in the mammal and human cochlea. (hearingreview.com)
From discovery of molecules that could induce regeneration in laboratory animals, it could be as little as another 10 years until we achieve hair cell regeneration in humans. (hearingreview.com)
Plikus at UCI and Cheng-Ming Chuong, professor of pathology at the Keck School of Medicine of USC and the study's co-lead investigator, are experts on hair regeneration. (scienceblog.com)
Our study suggests that melanocyte stem cells are mobile but can start the regeneration of hair melanocytes only when they are present in a specific area within the hair follicle (hair germ compartment). (medicalnewstoday.com)
Stem cells in the body are responsible for the regeneration of tissue in the body and can differentiate to form an array of specialized cells. (medicalnewstoday.com)

Adult (or tissue-specific) stem cells reside in many different organs and play important roles in maintaining the integrity of those tissues," says Shin, the lead author of the paper and an Alberta Innovates MD PhD scholar. (ucalgary.ca)
Researchers have been studying their ability to replace aged or damaged tissues and cells in a bid to understand the mechanisms underlying their longevity. (sciencedaily.com)
This means that the stem cells are no longer able to divide and so become less able to replace exhausted specialised cells in the tissues of our bodies. (sciencedaily.com)
They were then able to confidently measure its activity and resulting telomere length and found that asexual worms dramatically increase the activity of this gene when they regenerate, allowing stem cells to maintain their telomeres as they divide to replace missing tissues. (sciencedaily.com)
These structures help hold neighboring cells together, which provides strength and stability to tissues. (medlineplus.gov)
It's the equivalent of a DNA detangler that relaxes the tension of reprogramming transcription and makes it easier to replicate new cell colonies or tissues in a lab. (usc.edu)
It appears to be essential for the formation of tissues that arise from an embryonic cell layer called the ectoderm. (medlineplus.gov)
The resulting shortage of functional WNT10A protein disrupts Wnt signaling during the development of ectodermal tissues, including the skin, hair, nails, teeth, and sweat glands. (medlineplus.gov)
The research team had set up a system to grow human skin in the lab, starting with induced pluripotent stem cells, naïve adult human cells with the potential to give rise to many other kinds of tissues. (alleninstitute.org)
These findings are particularly exciting because they present a significant step towards developing new radiation therapy protocols that include minimizing negative side effects on normal tissues, such as hair or bone marrow, while maintaining the desired effects on cancer cells," says Maksim Plikus, assistant professor of developmental and cell biology at UCI and the study's first author. (scienceblog.com)
iPSCs directed to differentiate into specific cell types offer the possibility of a renewable source of replacement cells and tissues to treat ailments, including Parkinson's disease, spinal cord injury, heart disease, diabetes, and arthritis. (medindia.net)
How old your cells, tissues, and organs appear to be based on your body's overall health and functioning. (medlineplus.gov)

I believe the results could help develop cures for baldness," said Nishimura, a specialist in stem cell biology. (japantimes.co.jp)

First, a hair follicle contains epithelial cells - a cell type that lines the body's vessels and cavities - as well as a specific kind of adult stem cell called dermal papillae. (scienceblog.com)
Using publicly available single-cell RNA sequencing datasets we show that the α2A isoform is the most abundant adrenergic receptor in small intestinal epithelial cells. (bvsalud.org)

There is good evidence that similar fibroblasts, or progenitor cells, reside in most organs in the body and so they may undergo similar age-related degeneration to what Wisoo has uncovered in the hair follicle," says Biernaskie. (ucalgary.ca)
NOTCH1 is known to be required to produce hematopoietic progenitor cells with T cell potential in vivo. (scienceboard.net)
The pigmentation of the hair is then regulated by the stem cell factor (SCF) expression in hair shaft progenitor cells. (news-medical.net)
According to the study in a mouse model, the fur turned white when the SCF gene in the hair progenitor cells was deleted. (news-medical.net)

They are known as hair cells because the cells are covered in hair-like structures that serve as mechanical antennas for sound detection. (news-medical.net)
These hair-like structures are known as stereocilia, and Shin's new research shows a process they use to repair themselves. (news-medical.net)
In a study published in PLOS ONE, a team lead by Dr. Alexey Terskikh, PhD, found that human pluripotent stem cells (HPSCs) could be effectively programmed to form into derma papilla cells, special structures that are known to induce control over the growth cycle of the hair follicle. (miamihair.com)
Compared to studying individual cells in a petri dish, organoids allow researchers to study cells in more lifelike environs, as the clumps of tissue will form different types of structures akin to real organs in the body. (alleninstitute.org)
These glowing structures allowed the researchers to better track the formation of different skin layers in the organoids - they could see the epidermis developing in real-time as the fluorescent signal got brighter under the microscope. (alleninstitute.org)
Hair follicles, the structures that produce hair , undergo several cycles of growth over an individual's lifetime. (medicalnewstoday.com)
Ideally, Supp wants to create even better cultured skin, with cells that can grow the molecular structures required to produce sweat, hair, and pigment. (technologyreview.com)
If we can start with two cell types and add one or two genes at a time and get these structures to develop, that would be very exciting," she says. (technologyreview.com)
He added that HIV could also lead to hearing loss "via direct effects on ear structures or specialized ear cells themselves," or indirectly, by suppressing the immune response that protects against bacterial or fungal infection. (healthline.com)
Researchers have reproduced the wafting motion of hair-like structures on cell surfaces with tiny magnetic rods and a rotating magnetic field. (aps.org)

The authors include lead researcher Judith S. Kempfle, as well as Christine Hamadani, Nicholas Koen, Albert S. Edge and David H. Jung of Harvard Medical School and The Eaton-Peabody Laboratories in Boston. (disabled-world.com)
That research was later published in Nature and garnered DeepMind CEO Demis Hassabis and lead researcher John Jumper a $3 million Breakthrough Prize . (forbes.com)

Tiny clumps of skin grown from human stem cells - complete with hair follicles - represent the most lifelike human skin grown in the lab to date. (alleninstitute.org)
But new research published in Cell Reports this week describes the work of an Indiana University team that's successfully grown mouse skin complete with hair follicles in the lab. (sciencefriday.com)

Vestibular hair cells serve as sensory receptors in the inner ear that function to assess and monitor head motion, a sense of balance, allowing humans and animals to orient themselves," Dr. Robert Glatter , an emergency physician at Lenox Hill Hospital in New York, told Healthline. (healthline.com)
According to Glatter, the takeaway is that this study found that vestibular hair cells and Schwann cells express proteins that are essential for SARS-CoV-2 to enter cells. (healthline.com)
These medications can damage vestibular hair cells and typically lead to progressive ataxia and/or oscillopsia. (medscape.com)

Shin compared fibroblasts from different aged animals - young, middle-aged and older - to understand which particular genes are changing with advanced age and how they might contribute to the cell dysfunction. (ucalgary.ca)
The ATOH1 and GF1 genes are needed to make a cochlear hair cell from a non-hair cell. (hearingreview.com)
Wnt signaling controls the activity of certain genes and regulates the interactions between cells during embryonic development. (medlineplus.gov)
To date, CRISPR enzymes have been used to edit the genomes of one type of cell at a time: They cut, delete, or add genes to a specific kind of cell within a tissue or organ, for example, or to one kind of microbe growing in isolation in a test tube. (eurekalert.org)
Eventually, we may be able to eliminate genes that cause sickness in your gut bacteria or make plants more efficient by engineering their microbial partners," said co-first author Brady Cress, a postdoctoral researcher in Jennifer Doudna's lab. (eurekalert.org)
By adding three genes, they converted those cells into induced pluripotent stem cells (iPSCs), which have the capability to differentiate into any cell types in the body. (scienceblog.com)
What's more, the process Xu used to create iPSCs involves genetic modification of human cells with genes encoding oncogenic proteins and so needs more refinement. (scienceblog.com)
To make the new crystals, the researchers fused genes encoding ferritin and Inkabox-PAK4cat and expressed the new protein in human cells in a petri dish. (acs.org)
The study published online in the journal Genes & Development shows that the protein KROX20, is turned on in skin cells that devlop into the hair shaft. (news-medical.net)
Then, midway through Amanda's pregnancy, the couple read an article about Victoria Gray, a woman whose genes had been experimentally edited to treat her sickle cell disease. (investorvillage.com)
Researchers have identified two genes that may contribute to Raynaud phenomenon, a condition where blood vessels in the extremities constrict and limit blood flow. (medscape.com)
The researchers identified two genes that are likely involved with Raynaud. (medscape.com)

Ichida is the lead author, joined by a team of researchers at the Keck School. (usc.edu)

The goal would be to reprogram supporting cells, which are latticed among the hair cells and provide them with structural support, into outer or inner hair cells. (hearingreview.com)

Pinning proteins to its genetic material at the height of inflammation, the cells bookmark where they left off in their last tussle. (scitechdaily.com)
Two signaling proteins normally produced during hair growth-endothelin (or Edn) and Wnt-were required for this transformation. (nih.gov)
Those cells were then purified using the proteins they expressed on their surfaces. (scienceblog.com)
Proteins are large molecules formed from folded chains of amino acids, and are the building blocks of bacteria, microbes and human cells. (forbes.com)
These proteins include the ACE2 receptor, which is found on the surface of cells," he said, "and two enzymes called furin and transmembrane protease serine 2 (TMPRSS2) , which allow SARS-CoV-2 to attach to the host cell. (healthline.com)
But previous attempts to magnetize cells by producing iron-containing proteins inside them have resulted in only weak magnetic forces. (acs.org)
The new area of magnetogenetics seeks to use genetically encoded proteins that are sensitive to magnetic fields to study and manipulate cells. (acs.org)
The researchers wondered if they could line the hollow interiors of the crystals with ferritin proteins to store larger amounts of iron that would generate substantial magnetic forces. (acs.org)
Thymic stem cells actively participate in their environment by generating extracellular matrix proteins, essentially forming their own support system. (medindia.net)
Biologists have long recognized that cellular fluid is stirred by molecular motor proteins marching along a network of cell-spanning microtubules, but the cause of the vortex flow transition has remained unclear. (aps.org)
The researchers deploy the virus by attaching small proteins, called signal peptides, to its exterior that cause the virus to "seek out" particular cells, such as cancer cells. (eurekalert.org)

This is similar to humans' vision-related brain cells. (ucf.edu)
Melanin is a natural pigment that gives color to the skin, hair, and eyes in humans and animals. (eurekalert.org)
When I started this work, somebody said to me that I d never be able to restore the complexity and intricacies of hair cells in humans or other mammals. (hearingreview.com)
Discovering that mouse hair has a circadian clock - a 24-hour cycle of growth followed by restorative repair - researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given late in the day. (scienceblog.com)
The cells therefore could hold promise for successful transplantation in humans. (medindia.net)

By using an inhibitor of Notch signaling, we could push even more cells to differentiate into hair cells," says Dr. Edge. (science20.com)
In the other location-called the hair germ area-McSCs can differentiate to form melanocytes that produce melanin pigment for hair. (medicalnewstoday.com)
Specifically, the division of a stem cell can result in the formation of identical daughter stem cells and/or cells that can differentiate to assume different fates. (medicalnewstoday.com)
The approach adopted by researchers at TU Berlin for the natural growth of third teeth is as simple as it is ingenious: They remove dental pulp cells from the interior of an extracted tooth, which they then cultivate and de-differentiate in such a way as to produce an active embryonic tooth germ. (bionity.com)
iPSCs are cells that have been genetically reprogrammed to an embryonic stem-cell-like state, meaning that they can differentiate into virtually any of the body's different cell types. (medindia.net)

Understanding and harnessing internal mechanisms by which hair cells counteract wear and tear will be crucial in identifying ways to prevent age-related hearing loss. (news-medical.net)
The death of outer hair cells made by the cochlea are most often the cause of deafness and hearing loss. (hearingreview.com)
One of the major causes of hearing loss in mammals is damage to the sound-sensing hair cells in the inner ear. (science20.com)
Researchers at USC and Harvard have developed a new approach to repair cells deep inside the ear - a potential remedy that could restore hearing for millions of elderly people and others who suffer hearing loss. (disabled-world.com)

We'll be able to cultivate whole hair follicles in the lab by using stem cells taken from the patient themselves. (the-psa.co.uk)

Inflamed mouse stem cells located in the basal layer (red) of the epidermis and FOS (green), a near-universal stress response factor essential to inflammatory memory. (scitechdaily.com)
Some studies suggest that these stem cells may undergo oncogenic (cancer causing) changes, migrate into the epidermis, and develop into melanoma. (nih.gov)
The researchers found that with the start of the hair's growth phase, mutated melanocyte stem cells migrated up the hair follicle and into the epidermis. (nih.gov)
It had layers of dermis and epidermis, just like real skin, and tiny mouse hair follicles. (alleninstitute.org)
They have grown mouse skin complete with dermis, epidermis, and hair follicles. (sciencefriday.com)
That's kind of one of the revelations from this study is that the way we're generating the cells, we're generating the epidermis and the dermis together. (sciencefriday.com)

This is a really important study in highlighting how aging impacts tissue-resident stem cells and the molecular changes behind this degenerative process. (ucalgary.ca)
But the molecular mechanism that explained this process, and how the cell could use it to respond to types of inflammation and injury that it had never seen before, remained a mystery. (scitechdaily.com)
In collaboration with the rest of the team, he also went some way to understanding the clever molecular trick that enabled cells to go on dividing indefinitely without suffering from shortened chromosome ends. (sciencedaily.com)
They developed a continuum model that treats the dense array of microtubules as a deformable porous medium and showed how molecular motors translating along microtubules lead to inward-pointing forces on the fluid in the cell. (aps.org)
He dubbed sickle cell the first "molecular" disease - a new paradigm that would shape biomedical research for decades. (investorvillage.com)
We therefore investigated the effect of sympathetic neuronal activation on intestinal cells in mouse models and organoid cultures, to identify the molecular routes involved. (bvsalud.org)

If the findings can be applied to older animals, they may lead to ways to help stimulate cell replacement in adults and to the design of new treatment strategies for people suffering from deafness due to hair cell loss. (science20.com)
The findings appeared Sept. 12 in Cell Stem Cell in a research paper titled, "Mitigating antagonism between transcription and proliferation allows near-deterministic cellular reprogramming. (usc.edu)
The findings will require confirmation in human studies, but they suggest that melanoma can arise from melanocyte stem cells in hair follicles as well as from melanocytes in skin layers. (nih.gov)
New research in monkeys refutes these findings, suggesting that in primates like us, such cells will not be rejected by the immune system. (medindia.net)
These findings give a rationale to start autologous transplantation at least of neural cells in clinical situations," says senior author Dr. Jun Takahashi, of the Kyoto University's Center for iPS Cell Research and Application. (medindia.net)
The findings provide a first quantitative description of an observed developmental transition in the fruit fly cell. (aps.org)

Then they grew these iPSC-derived heart cells on a graphene surface. (phys.org)
Comparison of the gene expression patterns of the human iPSC-derived epithelial stem cells with epithelial stem cells obtained from human hair follicles showed that the team had succeeded in producing the cells they set out to make in the first place. (scienceblog.com)
That said, iPSC-derived epithelial stem cells are not yet ready for use in human subjects, Xu adds. (scienceblog.com)
Xu and his team mixed iPSC-derived EpSCs and mouse dermal cells to generate hair follicles to achieve the growth of the follicles. (scienceblog.com)
Studies in rodents have suggested that iPSC-derived cells used for transplantation may be rejected by the body's immune system. (medindia.net)

I feel that, within 5-10 years, we could easily find out if it s possible to regenerate hair cells at robust levels sufficient to restore hearing in mammals. (hearingreview.com)

The inner cells transmit those vibrations to the neurons to create the sounds we hear. (hearingreview.com)
Over time, hair-like sensory cells and bundles of neurons that transmit their vibrations break down, as do ribbon-like synapses, which connect the cells. (disabled-world.com)
The pairing of the two delivered the breakthrough solution, the researchers said, as neurons responded to the molecule, regenerating synapses in mouse ear tissue that led to repair of the hair cells and neurons, which are essential to hearing. (disabled-world.com)
In the paper, publishing September 26 in the ISSCR's journal Stem Cell Reports , published by Cell Press, iPSCs from nonhuman primates successfully developed into the neurons depleted by Parkinson's disease while eliciting only a minimal immune response. (medindia.net)
I also collaborate with neural stem cell researchers on developing an interface between computer chips and living neurons. (lu.se)

The hair cells do this by deploying a protein called XIRP2, which has the ability to sense damage to the cores, which are made of a substance called actin. (news-medical.net)
Here, the cells are also engineered to produce a red fluorescent protein when stimulated by green light. (phys.org)
In their latest work, the investigators found that blocking the Notch pathway increases the formation of new hair cells not from remaining hair cells but from certain nearby supporting cells that express a protein called Lgr5. (science20.com)
The resulting abnormal version of the desmocollin-2 protein alters the structure of desmosomes, preventing cells from attaching to one another effectively. (medlineplus.gov)
Researchers believe that the WNT10A protein is particularly important for the formation and shaping of both baby (primary) teeth and adult (permanent) teeth. (medlineplus.gov)
The researchers designed a molecule combining 7,8-dihydroxyflavone, which mimics a protein critical for development and function of the nervous system, and bisphosphonate, a type of drug that sticks to bones. (disabled-world.com)
Here, cells that were genetically modified to produce higher levels of a protein known as human beta defensin 4 are shown in green. (technologyreview.com)
So Supp and colleagues genetically modified skin cells to produce higher levels of an antibacterial protein. (technologyreview.com)
Now, researchers reporting in ACS' Nano Letters have engineered genetically encoded protein crystals that can generate magnetic forces many times stronger than those already reported. (acs.org)
To drastically increase the amount of iron that a protein assembly can store, Bianxiao Cui and colleagues wanted to combine the iron-binding ability of ferritin with the self-assembly properties of another protein, called Inkabox-PAK4cat, that can form huge, spindle-shaped crystals inside cells. (acs.org)
These magnetic protein crystals, isolated from cells, were stained with a blue dye that binds to iron. (acs.org)
However, the details about the actions when the stem cells move down to the base, or bulb, of hair follicles, are still unknown, along with which cells in the follicles of the hair produce SCF or that cells involved in the creation of the hair shaft generates the KROX20 protein. (news-medical.net)
then, with some adept genetic manipulation, they positioned the protein in the right part of the right cells in the mouse brain. (harvard.edu)
Decades before Jimi was born, chemist Linus Pauling discovered the root of the problem in sickle cell disease: an atypical form of the oxygen-carrying hemoglobin protein inside red blood cells. (investorvillage.com)

The group believes that directing human ES cells to neural crest cells ?might limit the variety of mesenchymal cell types to the subset that is developmentally specified downstream from NC cells in skin (e.g. cephalic DP during development, melanocytes, cephalic bulge). (lifecoderx.com)
Melanocyte stem cells, the source of melanocytes, are found in the lower portion of hair follicles. (nih.gov)
The hair-sprouting skin organoids also developed melanocytes (pink), which are cells that produce the skin and hair's pigment, melanin. (alleninstitute.org)
The loss of pigmentation occurs when cells that produce pigment, called melanocytes, are destroyed. (pfizer.com)
Vitiligo begins with the death of melanocytes, the cells responsible for giving your skin and hair their color. (pfizer.com)
The increase in the number of follicle growth cycles with aging is associated with deficits in melanocyte stem cells (McSCs) , the stem cells residing in the follicle that can form hair pigment-producing melanocytes. (medicalnewstoday.com)
Instead, a recent study published in Nature suggests that the McSCs can migrate back and forth between the two aforementioned locations, differentiating to produce hair pigment-producing melanocytes in the hair germ area and then translocating to the bulge and dedifferentiating to ensure the maintenance of an adequate supply of stem cells. (medicalnewstoday.com)
This results in fewer stem cells that can develop into pigment-producing melanocytes, thus leading to hair graying. (medicalnewstoday.com)
Moving melanocytes to a proper location within the hair follicle may help prevent hair greying. (medicalnewstoday.com)

Melanocyte stem cells are found within hair follicles, shown here. (nih.gov)
Hair follicles contain several different types of cells, including melanocyte stem cells that generate cells that produce the pigment melanin responsible for hair color. (medicalnewstoday.com)
The study found that aging results in a greater portion of these melanocyte stem cells getting stuck at the site where they produce stem cells, which leaves a smaller portion of stem cells to generate melanin-producing cells, resulting in the graying of hair. (medicalnewstoday.com)
Melanocyte stem cells are found in two distinct locations at the base of each hair follicle. (medicalnewstoday.com)
D . , a cell biologist at New York University, said, "[Our] analysis revealed melanocyte stem cells are more dynamic/mobile than previously thought. (medicalnewstoday.com)
We revealed that as melanocyte stem cells move within the hair follicle, stem cells can reversibly alter cell state from immature to mature state, and this reversibility is critical for the proper maintenance of these stem cells. (medicalnewstoday.com)
Dr. Ito also noted, "The study is built upon previous studies showing that maintaining healthy melanocyte stem cells is the key to preserving hair color. (medicalnewstoday.com)

But a study from the University of Calgary Faculty of Veterinary Medicine (UCVM) has found that it's actually a small population of specialized cells within the hair follicle called fibroblasts, and the dermal stem cells that maintain them, that may cause hair loss. (ucalgary.ca)
Our finding gives us the first clear cell switch to make one type versus the other," said lead study author Jaime García-Añoveros, PhD , professor of anesthesiology and neuroscience and in the Ken and Ruth Davee Department of Neurology . (hearingreview.com)
In this study, the researchers generated heart cells from donated skin cells, via an intermediary cell type called an induced pluripotent stem cell (iPSC). (phys.org)
A study from the U.S. Department of Health and Human Services' National Institutes of Health found that women who use chemical hair straighteners containing the toxin face more than twice the risk of developing endometrial cancer. (uc.edu)
In a study featured as the cover article appearing today in the journal Science Advances , a UCF research team showed that by combining two promising nanomaterials into a new superstructure, they could create a nanoscale device that mimics the neural pathways of brain cells used for human vision. (ucf.edu)
Now, a new study in Cell Stem Cell describes the mechanism behind inflammatory memory, also commonly referred to as trained immunity, and suggests that the phenomenon may be universal across diverse cell types. (scitechdaily.com)
Whereas previous research indicated that hair cells are not replaced, this latest study found that replacement does indeed occur, but at very low levels. (science20.com)
The lab study demonstrates a novel way for a drug to zero in on damaged nerves and cells inside the ear. (disabled-world.com)
The study breaks new ground because researchers developed a novel drug-delivery method. (disabled-world.com)
In the Xu study, the team's protocol succeeded in turning over 25% of the iPSCs into epithelial stem cells in 18 days. (scienceblog.com)
There are at least 400 medicinal plants present in nature which can be effective in reducing the amount of sugar level in the blood which is necessary to control Type 2 diabetes," said researchers from the Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) in Puducherry and the All India Institute of Medical Sciences in Kalyani, West Bengal, in a study published in the World Journal of Diabetes. (daijiworld.com)
In their study, published November 3 in the journal Stem Cell Reports , researchers from Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center based their method on Notch stimulation -- a pathway involved in cell fate decisions, proliferation, and death. (scienceboard.net)
A study discovered a new underlying mechanism with stem cells causing the hair to turn gray, which could lead to potential treatment. (medicalnewstoday.com)
The study also showed that the migration of the cells between these regions is disrupted with repeated hair follicle growth cycles. (medicalnewstoday.com)
Our study also suggests that melanocyte stem cell localization may be altered during the course of aging. (medicalnewstoday.com)
The study results could help in identifying feasible treatments for balding and hair graying. (news-medical.net)
The study has found that in mouse models, the hair turns gray without SCF, as age progresses the hair turns to white, and hair growth is arrested without KROX20-producing cells. (news-medical.net)
Researchers may be able to study the genetic variation in those with ALS. (cdc.gov)

Terskikh?s group believes their creation of neural crest cells from ES cells, which then formed dermal papilla cells, was a key step. (lifecoderx.com)
So Terskikh?s group first worked on persuading their pluripotent cells to become neural crest cells. (lifecoderx.com)
In contrast, all the supporting and Schwann cells are derived from neural crest cells, possibly from the VIIth nerve ganglion to which the vestibulocochlear ganglion is initially attached. (medscape.com)

However, researchers still can't grow functional skin, with hair follicles and sweat glands, to completion yet. (sciencefriday.com)
And it's not that surprising because sweat glands- these are mouse hairs, remember. (sciencefriday.com)

Our stem cell method provides an unlimited source of cells for the patient for transplantation," says Dr. Terskikh. (miamihair.com)
For patients suffering from severe hair loss who do not have fine hair for hair transplantation, specialists keep their fingers crossed that stem cell therapies will be a more effective treatment choice. (the-psa.co.uk)
In contrast, injections of the cells into immunologically unmatched recipients (called an allogeneic transplantation) caused the body to mount a stronger immune response. (medindia.net)

Dermal papilla cells regulate hair-follicle formation and growth cycle. (lifecoderx.com)

Wisoo Shin is lead author on a paper published in Developmental Cell on dermal skin cells. (ucalgary.ca)
The group said adult skin-derived precursors have been found in the past to be ?highly potent in hair induction, but progressive loss? (lifecoderx.com)
One explanation, the Fuchs team proposed, could be epigenetic changes to the skin cell genome itself. (scitechdaily.com)
Researchers suspect that the impaired connections between cells make the skin, hair, and heart muscle more fragile. (medlineplus.gov)
This mechanism probably underlies the skin, hair, and heart problems that occur in keratoderma with woolly hair type III. (medlineplus.gov)
It is unclear why some mutations in this gene affect the skin and hair, while others do not. (medlineplus.gov)
OODD is characterized by dry hair, missing teeth, a smooth tongue, fingernail and toenail abnormalities, thickened skin on the palms of the hands and soles of the feet (palmoplantar keratoderma), and increased sweating (hyperhidrosis) of the palms and soles. (medlineplus.gov)
A rare form of skin cancer may sometimes start with cancer-causing mutations in hair follicle stem cells. (nih.gov)
These cells are found in the skin, eyes, and hair. (nih.gov)
Researchers have succeeded in growing the most lifelike human skin in the lab to date. (alleninstitute.org)
Allen Institute for Cell Science cell lines formed the basis for the human skin organoids. (alleninstitute.org)
With its complex layers and different types of cells, skin takes a while to form, be it in a petri dish or a growing human. (alleninstitute.org)
After 10 weeks, the team finally saw what they were waiting for: The tiny clumps of skin-in-a-dish were growing hair follicles. (alleninstitute.org)
Growing hair isn't the end goal, Koehler said, although this is the first time hairy human skin has been made in the lab. (alleninstitute.org)
Rather, the hair is a marker of mature, developed human skin - what turns out to be a more lifelike version of skin than anyone else has yet managed to engineer. (alleninstitute.org)
The research team has already shown that in a mouse model of wound healing, these little skin blobs flatten out and grow into a skin sheet, complete with tufts of black hair. (alleninstitute.org)
Through the course of that project, which used mouse stem cells rather than human cells, he and his colleagues managed to generate skin tissue as a by-product. (alleninstitute.org)
So they set out to replicate the process using human stem cells, adding additional steps to get the skin to further mature and develop. (alleninstitute.org)
Ironically, the Allen Cell Collection is built from stem cells first generated at the Gladstone Institutes from an adult donor's skin cells - although that doesn't mean the stem cells are more similar to skin than they are to other types of tissue. (alleninstitute.org)
The team used one of the first stem cell lines released from the collection as the basis for their human skin organoids. (alleninstitute.org)
Xu and his team, which includes researchers from Penn's departments of Dermatology and Biology, as well as the New Jersey Institute of Technology, started with human skin cells called dermal fibroblasts. (scienceblog.com)
In parts of the inner ear of some animals, there is ongoing production and death of hair cells (like the turnover of skin cells) throughout life. (hearingreview.com)
Primarily viewed as a skin condition, vitiligo can also affect hair, eyes, inner ear, and mucous membranes (inside the mouth and nose). (pfizer.com)
Each strand of hair consists of the outer visible part called the shaft and the root that lies beneath the surface of the skin. (medicalnewstoday.com)
Skin cells genetically engineered to be resistant to bacteria could reduce infections and improve chances of survival among burn victims. (technologyreview.com)
A patient's skin cells, genetically modified and grown in a test tube, could provide the next generation of artificial skin. (technologyreview.com)
Genetically modified skin cells may help protect cultured skin substitutes from infection. (technologyreview.com)
We're using genetic modification to try to get the cultured skin to behave more like normal skin," says Dorothy Supp, a researcher at the Cincinnati Shriners Hospital for Children who led the project. (technologyreview.com)
In an experimental method developed by Steven Boyce of the University of Cincinnati, a patient's own skin cells are biopsied and then grown in culture. (technologyreview.com)
In a paper published in the current issue of the Journal of Burn Care and Research , Supp showed that these skin cells, when grown in a test tube, could kill more of a specific kind of bacteria than standard skin cells. (technologyreview.com)
Advances in stem cells have made it possible to grow and transfer nascent skin tissue to animals. (sciencefriday.com)
And what better way to update that monster story where body parts are stolen from graves than to discuss one from this century where body parts are being grown in the labs from stem cells- specifically, skin. (sciencefriday.com)
Skin represents a challenge because, even though you can't see them, skin has dozens of types of cells. (sciencefriday.com)
What we know about how the inner ear develops is that it actually develops from the same sheet of cells that the skin does. (sciencefriday.com)
IRA FLATOW: So you get the hair follicles which is very important to skin. (sciencefriday.com)
Things like skin pigmentation and a high level of compounds only found when new hair growth begins. (bgr.com)
In the case of teeth, certain precursor cells cluster together in the jaw beneath the outer skin layer. (bionity.com)
SkinCarePhysicians.com provides patients with up-to-date information on the treatment and management of disorders of the skin, hair and nails. (bvsalud.org)

In a paper published in Developmental Cell , Dr. Jeff Biernaskie, PhD, and his team, led by graduate student Wisoo Shin (pictured above), demonstrate that with increasing age, these dermal stem cells become dysfunctional and lose their ability to self-renew. (ucalgary.ca)
A loss of dermal stem cells prevents production of new fibroblasts and so the population can't be maintained. (ucalgary.ca)
Jeff Biernaskie's team discovered that hair follicle dermal stem cells may be responsible for hair loss. (ucalgary.ca)
We found that with the hair follicle dermal stem cells, not only are the numbers declining, but their ability to acquire certain functions is also impaired. (ucalgary.ca)
Limited adult dermal papilla (DP) cells do not work as hair transplants as they generally can?t be obtained in the large amounts, and can quickly lose hair-follicle forming ability in culture. (lifecoderx.com)
We need to figure out a way to also make new dermal papillae cells, and no one has figured that part out yet. (scienceblog.com)

Most biomedical research relies on individual cells or cell cultures grown in plastic petri dishes or on glass plates. (phys.org)

from embryonic stem cells. (lifecoderx.com)
Here we describe for the first time the derivation of functional DP-like cells human embryonic stem cells. (lifecoderx.com)
Roland Lauster's team, however, sees a decisive competitive advantage in the method it has been pursuing: All other competing research groups use embryonic stem cells to produce embryonic tooth germs. (bionity.com)

The company focuses on development of cell therapies using a patient's own cells (autologous cell therapy). (wikipedia.org)
Is the patient's hair curly or straight, and if it is the latter, how can we grow them in a grid so that they have the same texture? (the-psa.co.uk)

They speculated the superior hair-creation capacity of their pluripotent cell derived DPs to most reported adult DPs may have to do with the resemblance of their cells to embryonic or neonatal DP precursor cells. (lifecoderx.com)

They then converted the iPS cells into epithelial stem cells, normally found at the bulge of hair follicles. (scienceblog.com)
In one of the locations-called the bulge- these McSCs undergo self-renewal to maintain a population of immature stem cells. (medicalnewstoday.com)
He further explained that researchers are aware that the stem cells contained in a bulge area of hair follicles are involved in making hair and that SCF is important for pigmented cells. (news-medical.net)

Fibroblasts in the hair follicle are important because they send messages to the keratinocytes, telling them when to divide and ultimately orchestrating the repeating cycles of hair follicle growth that allow continuous production of new hair. (ucalgary.ca)

Hair cells' found in the inner ear, are important both for our ability to hear and our sense of balance. (news-medical.net)
The company's expertise lies in isolation and exploitation of different cell populations found in the human hair follicle. (wikipedia.org)
At least one mutation in the DSC2 gene has been found to cause a form of keratoderma with woolly hair classified as type III. (medlineplus.gov)
The researchers found that cancer cells do not have circadian clocks, because they are dividing all the time. (scienceblog.com)
Researchers also found that the virus could infect two types of cells in the inner ear called Schwann and hair cells. (healthline.com)
Schwann cells, also found in the specialized apparatus of the inner ear known as the cochlea , are vital to hearing," he continued. (healthline.com)
In contrast, only in the past 20 years has the ototoxicity of chemicals found in the environment from contaminants in air, food or water, and in the workplace become a concern for researchers, toxicologists, audiologists, and other healthcare professionals. (cdc.gov)

This is of relevance not only for hair cell research, but the broader cell biology discipline. (news-medical.net)
Normally, if you introduce a new material in biology, you'd expect to see a certain number of cells killed in the process," Savchenko said. (phys.org)
By confirming that oncogenic pigment cells in hair follicles are a bona fide source of melanoma, we have a better understanding of this cancer's biology and new ideas about how to counter it," Ito says. (nih.gov)
The researchers, from Salk Institute for Biological Studies, the University of Southern California (USC) and the University of California, Irvine (UCI), worked out the precise timing of the hair circadian clock, and also uncovered the biology behind the clockwork - the molecules that tells hair when to grow and when to repair damage. (scienceblog.com)
Former Meta researchers who developed an AI language model for biology have raised $40 million to build new biological LLMs that can help develop everything from cancer-fighting programmable cells to organisms that clean up toxic waste. (forbes.com)
F ormer Meta researchers who developed an AI language model for biology have launched a new startup and raised at least $40 million, Forbes has learned. (forbes.com)

Hair transplants are among the most sought-after hair loss treatments. (miamihair.com)
The timing has to do with minimizing collateral damage from normal cells affected by these treatments. (scienceblog.com)
These results provide insight into the mechanisms underlying the graying of hair and could help devise treatments for the treatment of hair graying. (medicalnewstoday.com)
But the doctors, patients and others eager for sickle cell treatments say that turning gene editing into a viable therapy, then finding ways to make it widely accessible, will help carve a path for others to follow. (investorvillage.com)
These tiny "smart bombs" - each one thousands of times smaller than the width of a human hair - could lead to more effective chemotherapy treatments with greatly reduced, or even eliminated, side effects. (eurekalert.org)
The researchers believe that their method will alleviate the side effects of common chemotherapy treatments, while maximizing the effectiveness of the treatment. (eurekalert.org)

During a person's lifetime, each hair follicle undergoes several growth cycles that consist of three phases . (medicalnewstoday.com)
But the hairs consist of tightly packed bundles of microscopic hooks that trap small animals such as shrimp-like amphipods. (mbari.org)

Specifically, it targets the cochlea, a snail-like structure in the inner ear where sensitive cells convey sound to the brain. (disabled-world.com)
Histologic changes associated with aging occur throughout the auditory system from the hair cells of the cochlea to the auditory cortex in the temporal lobe of the brain. (medscape.com)
The fibers of the cochlear nerve originate from an aggregation of nerve cell bodies in the spiral ganglion, located in the modiolus of the cochlea. (medscape.com)

Each adult stem cell population acts a little bit differently in the body and, as a result, how they change due to aging is also different. (ucalgary.ca)
The difference is iPS cells are derived from adult cells, not in vitro fertilization (IVF) clinic embryos. (lifecoderx.com)
The clock is turned back on the adult cells, until they reach a pluripotent state like that of ES cells. (lifecoderx.com)
In 2013, a Columbia University and Durham University team reported pairing up to generatesignificant hair growth, for the first time, from adult DP cells using unique 3-D cultures. (lifecoderx.com)
Dr Aboobaker predicted that planarian worms actively maintain the ends of their chromosomes in adult stem cells, leading to theoretical immortality. (sciencedaily.com)

It will provide a previously unavailable tool to make an inner or outer hair cell. (hearingreview.com)
The outer hair cells expand and contract in response to the pressure from sound waves and amplify sound for the inner hair cells. (hearingreview.com)
It's like a ballet,"García-Añoveros says with awe as he describes the coordinated movement of the inner and outer cells. (hearingreview.com)
When the gene is blocked, the cell becomes an outer hair cell. (hearingreview.com)
Then the TBX2 would be turned on or off to produce the needed inner or outer cell. (hearingreview.com)
We can now figure out how to make specifically inner or outer hair cells and identify why the latter are more prone to dying and cause deafness,"García-Añoveros said. (hearingreview.com)
Diagram shows the working of the human outer and inner ear including exploded view of both hair and nerve cells. (disabled-world.com)
The longer central fibers, also called the primary auditory fibers, form the cochlear nerve, and the shorter, peripheral fibers extend to the bases of the inner and outer hair cells. (medscape.com)
The remainder cross the tunnel of Corti to innervate the outer hair cells. (medscape.com)

Despite these advancements, one of the limits of hair transplants is the fact that many patients usually require over one treatment if they keep losing their hair after the transplant. (the-psa.co.uk)

The finding that newborn hair cells regenerate spontaneously is novel," says senior author Dr. Albert Edge of Harvard Medical School and Massachusetts Eye and Ear Infirmary. (science20.com)

The discovery may shed light on the possibilities of alleviating aging and age-related characteristics in human cells. (sciencedaily.com)
The discovery, published in the Proceedings of the National Academy of Sciences , is part of a project funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and Medical Research Council (MRC) and may shed light on the possibilities of alleviating aging and age-related characteristics in human cells. (sciencedaily.com)
As a result of this case report, the National Institute of Environmental Health Sciences (NIEHS) examined the effects of these oils on human cells and reported that they mimic the effects of estrogen while dampening the effects of androgens. (medscape.com)

But the new UVA Health research shows these delicate cells have the ability to repair themselves from damage caused by loud noises or other forms of stress. (news-medical.net)
In a research area that will generate blockbuster profits if/when it pans out, a science team reported creating new hair cells from pluripotent stem cells in a recent issue of PLOS (Proceedings of the Library of Science) One. (lifecoderx.com)
Starting with procedures other research teams had previously worked out to convert iPSCs into keratinocytes, Xu's team demonstrated that by carefully controlling the timing of the growth factors the cells received, they could force the iPSCs to generate large numbers of epithelial stem cells. (scienceblog.com)
He's a co-author on the new research published this week in Cell Reports. (sciencefriday.com)
There is a glimmer of hope for those going through hair loss because researchers are coming up with increasingly creative and ingenious ways to either regenerate or replace the lost hair.There are many Advancements in Hair Research, which will allow the recovery of the hair strand . (the-psa.co.uk)
Innovative discoveries in male hair loss research uncover uncommon genetic variants tied to it. (medindia.net)
They can also be used in basic cell research in order to obtain a better understanding of the mechanisms behind diabetes and cancer. (lu.se)
Knowledge about human and environmental exposure to nanomaterials requires more research, and Lund researchers are contributing their expertise to this field. (lu.se)

For decades, researchers studying aging and hair loss have focused on keratinocytes, the cells that make up the bulk of the hair follicle and eventually give rise to the hair fibre. (ucalgary.ca)

At that time, my group was one of two that discovered mature birds had the remarkable natural ability to restore their inner ear hair cells. (hearingreview.com)

Mouse heart cells grown on graphene beat at a rate controlled by light stimulation (as indicated by a green circle at top left corner). (phys.org)
These researchers and their colleagues teamed together to find and then take apart the mouse hair circadian clock. (scienceblog.com)

Induced pluripotent stem cells (iPSCs) extracted from the patient itself may be extremely helpful in treating many disease. (medindia.net)
However, studies in rodents have suggested that the body may mount an immune response and destroy cells derived from iPSCs. (medindia.net)

The condition is caused a lack of blood vessels around the hair follicles. (bgr.com)
Because there's a lack of blood vessels, the follicles can't deliver the nutrients the body needs to produce hair. (bgr.com)
The main gene finding, ADRA2A , "points to a receptor on the cells that regulate the tone of these blood vessels," she continued. (medscape.com)

However, supporting Schwann and satellite cells, as in all cranial ganglia, are entirely of neural crest origin, apparently arising from the ganglion of the facial nerve (see the image below). (medscape.com)
These nerves are surrounded by Schwann cells beginning in the IAC close to the porus acusticus. (medscape.com)

Anatomy22

Organisms1

Diseases4

Chemicals and Drugs10

Analytical, Diagnostic and Therapeutic Techniques and Equipment14

Psychiatry and Psychology8

Phenomena and Processes7

Disciplines and Occupations16

Anthropology, Education, Sociology and Social Phenomena8

Humanities4

Information Science27

Named Groups2

Health Care29

Geographicals1

Mice35

Scientists21

Existing hair follicles1

Including hair follicle1

Scalp9

Differentiation8

Regeneration14

Tissues12

Baldness1

Epithelial cells2

Progenitor cells4

Structures10

Lead researcher2

Complete with hair follicles2

Vestibular hair cells3

Genes12

Team of researchers1

Reprogram suppo1

Proteins11

Humans5

Differentiate5

Hearing loss4

Follicles in the lab1

Epidermis6

Molecular6

Findings6

IPSC-derived5

Regenerate hair cells1

Neurons5

Protein14

Melanocytes9

Melanocyte stem cells7

Study18

Neural crest3

Sweat glands2

Transplantation3

Papilla cells1

Skin38

Dermal6

Petri1

Embryonic stem3

Patient's2

Pluripotent cell1

Bulge3

Follicle growth1

Found7

Biology6

Treatments6

Consist2

Cochlea3

Adult5

Outer9

Transplants1

Harvard1

Human cells3

Research8

Keratinocytes1

Inner Ear Hair Cells1

Mouse2

IPSCs2

Blood vessels3

Schwann2