Mycosis fungoides, also known as Alibert-Bazin syndrome or granuloma fungoides, is the most common form of cutaneous T-cell lymphoma. (wikipedia.org)
Mycosis fungoides (MF) and Sézary syndrome (SS) are related conditions, with the same type of cancer t-lymphocytes, that initially grow in different body compartments. (wikipedia.org)
Results from a multi-center phase III trial examiniing the safety and efficacy of two doses of denileukin diftitox (Ontak) in patients with biopsy-confirmed CD25 assay-positive cutaneous T-cell lymphoma (CTCL), including both mycosis fungoides and Sezary Syndrome suggest merely that this recombinant protein can outperform a placebo. (lymphomainfo.net)
In one such example, HTS was used to measure the patient-specific TCR sequences in patients with cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome) after a non-myeloablative allogeneic transplant. (stanford.edu)
4. Hristov A.C., Tejasvi T., Wilcox R.A. Mycosis fungoides and Sézary syndrome: 2019 update on diagnosis, risk-stratification, and management // Am J Hematol. (pdt-journal.com)
Mycosis fungoides and Sezary syndrome: an update // Curr Oncol Rep. - 2006. (pdt-journal.com)
EORTC consensus recommendations for the treatment of mycosis fungoides/Sezary syndrome // Eur J Cancer. (pdt-journal.com)
Revisions to the staging and classification of mycosis fungoides and Sézary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous task force of the European Organization for Research and Treatment of Cancer (EORTC) // Blood. (pdt-journal.com)
This phase I trial identifies the best dose, possible benefits, and/or side effects of duvelisib in combination with nivolumab in treating patients with stage IIB-IVB mycosis fungoides and Sezary syndrome. (clfoundation.org)
Giving duvelisib in combination with nivolumab may work better than giving each of these drugs individually, or treating with the usual approach in patients with mycosis fungoides and Sezary syndrome. (clfoundation.org)
RATIONALE: Lenalidomide may stop the growth of mycosis fungoides/Sezary syndrome by blocking blood flow to the cancer. (stanford.edu)
PURPOSE: This phase II trial is studying how well lenalidomide works in treating patients with relapsed mycosis fungoides/Sezary syndrome. (stanford.edu)
subtypes of cutaneous T-cell lymphoma, SS is a malignant neoplasm originating the most common of which are mycosis from T lymphocytes, which involves the fungoides and Sézary syndrome (SS). (bvsalud.org)
Mycosis fungoides can progress to what is called Sézary syndrome. (vin.com)
This complication almost never happens in dogs but happens in approximately 5 percent of humans with mycosis fungoides, so the term may come up if you do any internet research. (vin.com)
Cutaneous4
A molecular feature of Sezary syndrome (SS), the leukemic variant of cutaneous T-cell lymphomas (CTCL), is the abnormal gene expression of PLS3 in 3 out of 4 patients [1-9]. (symbiosisonlinepublishing.com)
KIR3DL2 is also a marker for atypical mononuclear (Sezary) cells in the blood of patients with Sezary syndrome, an erythrodermic form of cutaneous T cell lymphoma (11). (rndsystems.com)
Every donation will go towards providing education , support , advocacy efforts, raising awareness and funding research for people affected by cutaneous lymphomas worldwide. (clfoundation.org)
My research interests comprise cutaneous tumors with emphasis in lymphomas and melanoma. (mdanderson.org)
Lymphocytes1
We studied two human lymphocyte cell lines derived from tumor lymphocytes of patients with Sezary syndrome, HuT-78 cells which express PLS3 mRNA and SeAx cells that do not, for methylation status and used a well-established inhibitor of DNA methylation, the nucleoside analog 5-aza-2-deoxycytidine (5-aza-dC), to further determine its effect on PLS3 gene expression in both cell lines. (symbiosisonlinepublishing.com)
Lymphoma1
Begue E, Michel L, Jean-Louis F, Bagot M, Bensussan A (2013) Promoter Hypomethylation and Expression of PLS3 in Human Sezary Lymphoma Cells. (symbiosisonlinepublishing.com)
Patients4
Dr. Khan's research interests include therapeutic clinical trials as well as ways to reduce toxicities that some patients may experience when receiving cancer treatment. (stanfordhealthcare.org)
My research concentrates on clinical trials for patients with late-stage central nervous system cancer. (stanford.edu)
We assessed the clinicopathological features of 28 patients with peripheral neuropathy associated with Churg-Strauss syndrome. (lookformedical.com)
We believe that cysteinyl leukotriene type 1 receptor antagonists are safe and effective drugs for most patients with asthma but caution is needed for those with more severe disease who require systemic corticosteroids, especially if they show characteristics of the atypical allergic diathesis seen in the prodromal phase of Churg-Strauss syndrome. (lookformedical.com)
The question ought to be what are myelodysplastic syndromes (MDS), since this is a group of similar blood and bone marrow diseases that. (lymphomainfo.net)
Cells2
A bone marrow smear was performed, in which 'cerebriform' cells were identified, confirming the diagnosis of Sézary syndrome. (bvsalud.org)
Necrotizing vasculitis mediated by cytotoxic T cells, leading to ischaemic changes, appears to be a major cause of Churg-Strauss syndrome-associated neuropathy. (lookformedical.com)
Diagnosis2
This product is for research use only and is not approved for use in humans or in clinical diagnosis. (novusbio.com)
Available at https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2021/cancer-facts-and-figures-2021.pdf . (medscape.com)
Neuropathy1
Clinicopathological features of Churg-Strauss syndrome-associated neuropathy. (lookformedical.com)
Our results clearly revealed a quantitative relationship between the methylation status of the PLS3 CpG region and PLS3 expression in HuT-78 and SeAx Sezary cell lines. (symbiosisonlinepublishing.com)
Clinical Research1
NRG brings together internationally recognized groups (the first words in their names form the acronym "NRG") to conduct cancer clinical research and share study results. (stanfordhealthcare.org)
Oncology1
He has published numerous articles on his research discoveries in peer-reviewed journals such as the JAMA Oncology, Investigational New Drugs, and others. (stanfordhealthcare.org)
His research activities include ongoing clinical trials of targeted and immune therapy for aggressive thyroid cancer. (stanfordhealthcare.org)
A research study to learn about the biologic features of cancer development, growth, and spread. (stanford.edu)
Patient3
Bringing cuttng-edge technology to daily clinical patient care has been one of the research hallmarks of the Stanford BMT program. (stanford.edu)
Respiratory failure in a patient plus respiratory distress associated with bilateral basal rales, presented respiratory failure, and during induction of mechanical with Sézary syndrome. (bvsalud.org)
When not providing patient care or conducting research, Dr. Khan enjoys spending time with his family, hiking, and relaxing at the beach. (stanfordhealthcare.org)
Skin1
Regarding the epidemiological distribu- skin biopsy of the dorsal and anterior chest tion of this syndrome, it predominates in region. (bvsalud.org)
Cell line1
The Sezary cell line HuT-78 was purchased from European Collection of Animal Cell Cultures (ECACC, Salisbury, England). (symbiosisonlinepublishing.com)
TS supervised the research group, ran the statistical analysis, interpreted data, and was involved with manuscript drafting. (chk1inhibitor.com)
Study4
Medical records research - uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best. (mayo.edu)
El-Darouti et al reported on a 7-year study of a hypopigmented disorder that the researchers believe should be classified as a new variant of parapsoriasis en plaque. (medscape.com)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. (clfoundation.org)
cutánea maligna de células T. Luego se realizó el frotis de médula ósea, en el que se identificaron células «cerebriformes» study conception, manuscript que confirmaron el diagnóstico de síndrome de Sézary. (bvsalud.org)
GlobalData , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. (pharmaceutical-technology.com)
Materials1
Quartz vs Marble is a popular topic when researching materials for new Countertops. (wazeesupperclub.com)
Conditions1
Several cases of eosinophilic conditions including Churg-Strauss syndrome have been reported to be associated with zafirlukast, a cysteinyl leukotriene type 1 receptor antagonist. (lookformedical.com)
Health1
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. (mayo.edu)