Represent metabolic oxygen consumption. Medical search. Frequent questions

Although these techniques tackle the coupling between neuronal activity and metabolism, they lack chemical specificity and fail in providing information on neuronal and glial metabolic pathways underlying those processes. (frontiersin.org)
This shift in metabolic pathways generates only two ATP molecules per molecule of glucose and results in the accumulation of lactic acid. (medscape.com)
ATP generates either with oxygen, via the aerobic pathways, or without oxygen, through the anaerobic pathways, depending on the situation. (exercisedaily.com)
An increase in demand on anaerobic energy pathways during exercise might result in a larger demand on aerobic energy pathways post-exercise, which can raise the requirement for oxygen, therefore amplifying the EPOC effect. (exercisedaily.com)
Moreover, many canonical cancer-associated signaling pathways induce metabolic reprogramming. (pharmaceuticalintelligence.com)
Human biomonitoring samples have been analysed for identifying metabolomics and transcriptomics fingerprints, while they have also been mapped jointly into metabolic pathways, for identifying the perturbated pathways that are mostly associated with neurodegenerative diseases. (aiche.org)
[ 7 ] Inflammation-mediated events, such as the production of cytokines, reactive oxygen species, and mediators of the inflammatory pathways, such as cyclooxygenase (COX), may contribute to tumor formation. (medscape.com)
The diagram below illustrates metabolic pathways of carbohydrates. (medscape.com)
Metabolic pathways of carbohydrates. (medscape.com)
Carbohydrate metabolic pathways are blocked, leading to excess glycogen accumulation in affected tissues and/or disturbances in energy production. (medscape.com)

These levels include low, moderate, and vigorous and are measured by the metabolic equivalent of task (aka metabolic equivalent or METs). (wikipedia.org)
9) Moderate physical activity is activity performed at an intensity of 3 to 6 METs (work metabolic rate/resting metabolic rate) -- the equivalent of brisk walking at 3 to 4 mph for most healthy adults. (cdc.gov)
Moderate intensity is defined as activity that requires 3 METs (metabolic equivalents of task), or three times the amount of oxygen that's consumed while sitting still. (medicalxpress.com)
As you can see, there were no significant differences in HR, RPE, %HRmax or %VO 2 max between males and females, though males achieved significantly higher VO 2 and metabolic equivalents (METs) during the workout and expended significantly more calories than the females. (acefitness.org)
A portable metabolic unit was worn during each activity to measure metabolic equivalents (METs). (jmir.org)

The Youth Compendium was developed consisting of metabolic equivalents (METy) values for 196 specific activities classified into 16 major categories for four age-groups, 6-9, 10-12, 13-15, and 16-18 yr. (usda.gov)

To estimate the intensity of each activity, measured oxygen consumption (V' O2) was divided by basal metabolic rate(Schofield age-, sex-, and mass-specific equations) to produce a youth MET (METy). (usda.gov)
It's well established that as an adaptive response to reduced food availability, the body's basal metabolic rate is reduced, in order to lessen the negative impact of undernutrition, and it's easy to see the evolutionary reason why this happens. (psychologytoday.com)
These hormones enhance oxygen consumption by most tissues of the body, increase the basal metabolic rate, and the metabolism of carbohydrates, lipids, and proteins. (neotypestation.com)

In vivo experiments confirmed mitochondrial abundance and mitochondrial oxygen consumption rates were elevated in host tissues following MSC treatment. (frontiersin.org)
In addition, S1P exposure increased mitochondrial oxygen consumption rates (OCRs) in wild-type astrocytes and reduced OCRs in S1P 2 -null astrocytes, implicating receptor selective metabolic consequences of S1P-mediated glutamate uptake inhibition. (eneuro.org)

When performed correctly, Tabata increases your RMR (resting metabolic rate), which is the rate at which your body burns energy while at rest. (fitonapp.com)
It's about a 16 percent change in resting metabolic rate, which is enormous," says Justin Grobe. (futurity.org)
When researchers used a drug to change the gut microbiome in mice, they saw a reduction in resting metabolic rate-the rate at which calories are burned while sleeping or resting. (futurity.org)
They then showed that the altered microbiome causes a reduction in resting metabolic rate that is entirely responsible for the excess weight gain. (futurity.org)
With this study, we now have a mechanism for how a shift in the microbiome contributes to weight gain, and it's to do with changes to the resting metabolic rate. (futurity.org)
The researchers discovered there was no change in aerobic (oxygen-dependent) resting metabolic rate for mice fed risperidone compared to control mice, but there was a significant decrease in non-aerobic resting metabolic rate sufficient to account for the animals' weight gain. (futurity.org)
To prove that it was the "shifted" microbiome that was responsible for this metabolic change and the weight gain, the researchers transferred the microbiome from risperidone-fed mice into control mice and saw the same effect: decreased resting metabolic rate and increased weight gain. (futurity.org)
Transferring just a bacteriophage (phage)-a type of virus that infect microbiome bacteria-was sufficient to reduce resting metabolic rate and cause weight gain in the control mice. (futurity.org)
The results may suggest that manipulating resting metabolic rate, specifically by targeting the gut microbiome, could represent a new approach to treating obesity. (futurity.org)

We reasoned that the enhancement of the OCR leads to the production of reactive oxygen species (ROS), which are directly linked to PD-L1 induction. (allergy-link.com)
Many mechanisms of genotoxicity/carcinogenicity for PCBs appear to involve issue of reactive oxygen species/oxidative stress , including the appearance of oxidative DNA damage. (cdc.gov)
Individual ammocoete incubations suggested that biomass-specific oxygen consumption and ammonium, reactive phosphorus and silica excretion were size-dependent, and greater in small compared to large individuals. (mdpi.com)
The in vitro effects of metronidazole on the production of reactive oxygen species by polymorphonuclear (PMN) cells were studied by means of nitroblue tetrazolium and luminol-dependent chemiluminescence. (who.int)
At therapeutic doses of metronidazole (4.98-24.86 μg/mL) significant inhibition of the production of reactive oxygen species was noted in both methods. (who.int)
The data suggest a scavenging mechanism of metronidazole on reactive oxygen species generated by PMN. (who.int)

Blood flow is indeed directly related to the cerebral metabolic rate of glucose consumption (CMR glc ) ( Sokoloff, 1978 ). (frontiersin.org)
Target genes activated by hypoxia inducible factor (HIF) decrease the dependence of the cell on oxygen, whereas Ras, Myc, and Akt can also upregulate glucose consumption and glycolysis. (pharmaceuticalintelligence.com)

Although the adult human brain represents only 2% of the total body weight, it consumes up to 20% of the total glucose metabolism under normal resting physiological conditions (e.g. (frontiersin.org)
In the nonstressed physiologic state, adequate oxygen and glucose are delivered intracellularly to mitochondria that generate 36 adenosine triphosphate (ATP) molecules per glucose molecule via aerobic metabolism and the Krebs cycle. (medscape.com)
The roles of metabolism of OHPCBs (e.g., further oxidation, sulfation, and other metabolic reactions) in the disposition and toxicity represent a significant gap in our knowledge about mechanisms for carcinogenesis and other toxic responses to PCBs. (cdc.gov)
So, how does the metabolism-or more specifically, metabolic rate-actually change in refeeding? (psychologytoday.com)
Caffeine acute effects on oxygen metabolism are not well characterized across the brain with MRI. (ismrm.org)
These metabolic transitions are only just beginning to be understood, often relying on transcriptional data to infer metabolism, rather than actual metabolic outputs. (conditionmed.org)
Hence, configuring cell metabolism opposite to the preferences of the virus represents a potentially powerful anti-viral strategy. (nature.com)
Gene therapy displacement of endogenous MCUb with a dominant-negative MCUb transgene (MCUb W246R/V251E ) in vivo rescued T2D cardiomyocytes from metabolic inflexibility and stimulated cardiac contractile function and adrenergic responsiveness by enhancing phospholamban phosphorylation via protein kinase A. We conclude that MCUb represents one newly discovered molecular effector at the interface of metabolism and cardiac function, and its repression improves the outcome of the chronically stressed diabetic heart. (diabetesjournals.org)
Diabetes results in a cardiomyopathy characterized by decreased cardiomyocyte function, increased myocardial fatty acid utilization, decreased glucose utilization, increased myocardial oxygen consumption, and decreased cardiac efficiency ( 4 , 5 ), primarily as the result of changes in metabolism and Ca 2+ handling within the myocyte ( 3 , 6 , 7 ). (diabetesjournals.org)
Overcoming this shortcoming could represent a way to improve the robustness of the method and make it a new gold standard, even a potential Good Manufacturing Practices (GMP)-compliant validated method for metabolism studies, in the setting of quality control and monitoring of T cell based therapies productions. (antiviralbiologic.com)
It is widely acknowledged that metabolism influences the TDF, being responsible for different TDFs between tissues of variable metabolic activity (e.g. liver vs. muscle tissue) or species body size (small vs. large). (authorea.com)
This battery of measurements are used in the diagnosis and treatment of certain liver, heart, and kidney diseases, acid-base imbalance in the respiratory and metabolic systems, other diseases involving lipid metabolism and various endocrine disorders as well as other metabolic or nutritional disorders. (cdc.gov)

van Loon NM , Rensen PC , Zelcer N , . IDOL in metabolic, neurodegenerative and cardiovascular disease. (impactaging.com)
The next two series of presentations will open up this resurgence of fundamental metabolic research in cancer and even neurodegenerative diseases. (pharmaceuticalintelligence.com)
Glutamate neurotoxicity has been reported in multiple neurologic diseases including multiple sclerosis (MS), representing a shared neurodegenerative mechanism. (eneuro.org)

Cerebral function is associated with exceptionally high metabolic activity, and requires continuous supply of oxygen and nutrients from the blood stream. (frontiersin.org)
Cerebral function requires the cooperative interaction between different cell types, namely neurons, astrocytes, microglia and oligodendrocytes, and depends on high metabolic activity supported by continuous supply of oxygen and glucose from the blood ( Siesjö, 1978 ). (frontiersin.org)
Indeed the high acuity and high sensitivity of the visual system in higher vertebrates is critically dependent on the very high metabolic rates of the photoreceptor cells. (arn.org)

In the course of investigating metabolic defects in Sik3 -deficient mice ( Sik3 -/- ), we observed that circadian rhythmicity of the metabolisms was phase-delayed. (elifesciences.org)
The contribution of altered mitochondrial Ca 2+ handling to metabolic and functional defects in type 2 diabetic (T2D) mouse hearts is not well understood. (diabetesjournals.org)

Morbidity from shock may be widespread and can include central nervous system (CNS) failure, respiratory failure (ie, from muscle fatigue or acute respiratory distress syndrome [ARDS]), renal failure, hepatic dysfunction, gastrointestinal ischemia, disseminated intravascular coagulation (DIC), metabolic derangements, and ultimately death. (medscape.com)
Drivers (A and B). The metabolic derangements in cancer cells may arise either from the selection of cells that have adapted to the tumor microenvironment or from aberrant signaling due to oncogene activation. (pharmaceuticalintelligence.com)

This protein is found in a cellular compartment called the mitochondria, which is responsible for supplying energy to the rest of the cell and therefore plays an important role in metabolic processes. (elifesciences.org)
found that when this variant form of ATP5G1 was introduced into the cells of mice, their mitochondria was better at coping with stress conditions, such as low oxygen, low temperature and poisoning. (elifesciences.org)
Spectra™ has been reported to decrease ROS, increase cellular oxygen consumption in blood and mitochondria, decrease extracellular H2O2, and reduce TNFα-induced inflammatory response in humans. (undergroundnutritionnj.com)
Since iron is known to be a constituent of coenzymes facilitating metabolic processes in mitochondria, we examined the metabolic status of FAC-overloaded macrophages by measuring the oxygen consumption rate (OCR) and the represented coenzyme, aconitase. (allergy-link.com)
Hence, the increase in glycolysis associated with SARS-CoV-2 infection 3 might explain why many patients tolerate very low oxygen levels-presumably they are using glycolysis heavily and barely utilizing their mitochondria. (nature.com)

Although the sufficiency of tissue oxygenation cannot be directly measured and varies by time and tissue-type, the relationship of oxygenation delivery and consumption is key to understanding the pathophysiology of shock. (medscape.com)

However, the metabolic and bioenergetic processes associated with inflammation of bone are unknown. (stanford.edu)

In recent years, HCC has also been associated with obesity, diabetes, and the metabolic syndrome. (medscape.com)
Triiodothyronine (T3) levels are low in the fetus and newborn, in old age, in chronic caloric deprivation, hepatic cirrhosis, renal failure, surgical stress, and chronic illnesses representing what has been called the "T3 thyronine syndrome. (neotypestation.com)
Diabetes is a complex metabolic syndrome afflicting a growing number of people globally ( 1 ). (diabetesjournals.org)

Intensity is the amount of physical power (expressed as a percentage of the maximal oxygen consumption) that the body uses when performing an activity. (wikipedia.org)
Our maximum intensity is a reflection of our maximal oxygen consumption (VO2 max). (wikipedia.org)
Prior to the study, each participant performed a maximal exercise test on a treadmill to determine maximal heart rate (HRmax) and maximal oxygen uptake (VO 2 max). (acefitness.org)
Sequential addition of these two compounds corresponds respectively to Fes stressed-metabolic condition and Teneligliptin hydrobromide hydrate metabolic maximal capacities. (antiviralbiologic.com)

Described decades ago, the Warburg effect of aerobic glycolysis is a key metabolic hallmark of cancer, yet its significance remains unclear. (pharmaceuticalintelligence.com)
Although aerobic glycolysis has now been generally accepted as a metabolic hallmark of cancer, its causal relationship with cancer progression is still unclear. (pharmaceuticalintelligence.com)
Under aerobic conditions, there is enough oxygen to react with all the free radicals and addition of metronidazole, or any other sensitizers, yields no further benefit. (who.int)

Thus, 2DG in the murine heart appears to induce a metabolic configuration that is the opposite of SARS-CoV-2 infected cells, which could explain the compound's ability to restrict the propagation of the virus to the benefit of patients with COVID-19 disease. (nature.com)

could be used to identify and study other proteins that increase resilience to metabolic stress. (elifesciences.org)
Using biochemical assay, we also demonstrate that CASK can interact with metabolic proteins. (biomedcentral.com)

Shock is defined as a state of acute energy failure due to inadequate glucose substrate delivery, oxygen delivery, or mitochondrial failure at the cellular level. (medscape.com)
Although hypoxic or ischemia tolerance in AGS involves physiological adaptations, little is known about the critical cellular mechanisms underlying intrinsic AGS cell resilience to metabolic stress. (elifesciences.org)
For the first time anywhere, the biological effects of a natural supplement on the changes of oxidative and nitrosative stress markers, as well as cellular metabolic activity, have been clinically observed in the human body. (undergroundnutritionnj.com)

Relevant to the studies presented in this manuscript, mitochondrial dysfunction is a key contributor to the perpetuation of metabolic inflammation caused by nutrient excess. (frontiersin.org)
What Does Excess Postexercise Oxygen Consumption Represent? (exercisedaily.com)
What is Excess Post Exercise Oxygen Consumption? (exercisedaily.com)
EPOC (excess post-exercise oxygen consumption) explains this physiological consequence. (exercisedaily.com)
So, these are the functions for what does excess postexercise oxygen consumption represent? (exercisedaily.com)
So, what does HIIT has to do with "what does excess postexercise oxygen consumption represent? (exercisedaily.com)
This metabolic boost is due to a process known as EPOC, or excess post-exercise oxygen consumption. (fitonapp.com)

Results Assay design and impact on metabolic potential analysis It was considered that sufficient metabolic potential related information were displayed using glucose-containing culture medium at constant state, after adding oligomycin in the port A and carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (FCCP) in the port B of the Seahorse analyzer Teneligliptin hydrobromide hydrate plate. (antiviralbiologic.com)

A small, but typically insignificant, amount of oxygen is directly dissolved in the blood rather than bound to Hb. (medscape.com)
Radiosensitizers are chemical agents that have the potential to increase the lethal effect of radicals induced during irradiation [1-6].The extent of radiation damage to cells is dependent on the amount of oxygen available to the cell [1,2,7,8]. (who.int)

The research, published this month in the International Journal of Behavioral Nutrition and Physical Activity , offers walkers a concrete way to track their activity level without relying on exercise devices or complicated calculations about oxygen consumption or heart rate. (medicalxpress.com)
This Youth Compendium of Physical Activities uses pediatric data exclusively, addresses the age dependency of METy, and imputes missing METy values and thus represents advancement in physical activity research and practice. (usda.gov)
Benthic metabolic activity was quantified by aquatic eddy co-variance while water column activity was assessed by bottle incubations. (lancs.ac.uk)
High consumption rates of psychotropic substances, energy drinks, ergogenic substances and low levels of quality of life were found among teenagers with high levels of physical activity. (bvsalud.org)
Both protein-bound hormones exist in reverse equilibrium with minute amounts of free hormone, the latter accounting for the metabolic activity. (neotypestation.com)
I'm Commander Ibad Khan, and I'm representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communication Branch at the Centers for Disease Control and Prevention. (cdc.gov)
In the contemporary work place, many workers spend more than half of their entire work day seated (9), so the work place represents a community venue for the promotion of physical activity and the reduction of sedentary time (10). (cdc.gov)

Beyond this threshold, oxygen debt develops and blood lactate levels rise. (medscape.com)
In the metabolic symbiosis model, these cells have been proposed to overexpress MCT4 to release high amounts of lactate produced during anaerobic glycolysis into the tumor microenvironment. (hindawi.com)

The most precise measure of intensity is oxygen consumption (VO2). (wikipedia.org)
This table outlines the estimated distribution of energy consumption at different intensity levels for a healthy 20-year-old with a Max Heart Rate (MHR) of 200. (wikipedia.org)
The study seeks to establish the relationship between walking cadence (steps per minute) and intensity (metabolic rate) across the adult lifespan, from age 21 to 85. (medicalxpress.com)
2000 (http://www.cpc.unc.edu/projects/pin/design_pin3/docs_3/PIN-MET-Table-080207.pdf) were used to represent absolute intensity. (researchassistantresume.com)
The research team represented the intensity in terms of %HRmax and %VO 2 max, as that is how it is most often represented in the comparative literature. (acefitness.org)

[ 3-5 ] Major risk factors for HCC include chronic infections with hepatitis B and hepatitis C viruses, excessive alcohol consumption, certain rare metabolic disorders, and consumption of food contaminated with aflatoxin. (medscape.com)
Our data implies that some phenotypic components of CASK heterozygous deletion mutation associated disorders represent systemic manifestation of metabolic stress and therefore amenable to therapeutic intervention. (biomedcentral.com)
Together with pH determination, bicarbonate measurements are used in the diagnosis and treatment of numerous potentially serious disorders associated with acid-base imbalance in the respiratory and metabolic systems. (cdc.gov)

This timescale apparently represents the average period of hydrological imprint for carbon turnover within the reaches. (lancs.ac.uk)
The apparatus allows precise measurements of energy intake, oxygen consumption and carbon dioxide output, and heat production in a single animal to determine the total energy change, or "delta G," of the mouse. (futurity.org)
To use Closed-Circuit Escape Respirators (CCERs) as an example, NPPTL engineers work as part of a team with physical scientists, quality assurance specialists, and technicians to review the applications, evaluate the quality program, and conduct approval tests through the evaluation of oxygen delivery capacity and stressors, such as inhaled oxygen, inhaled carbon dioxide, breathing resistance, and wet bulb temperature. (cdc.gov)
These tests are conducted on an Automated Breathing Metabolic Simulator (ABMS), which is a machine that replicates the act of breathing (respiratory frequency, breath volume, flow, temperature, and humidity), oxygen consumption, and carbon dioxide production. (cdc.gov)

Cognizance of the singular energy balance is especially complicated, attributable to physiological pay to changes in energy admission and additionally consumption. (alliedacademies.org)
A total of 775 individuals representing 14 species were examined for outward physiological indication of male breeding readiness and grouped latitudinally into two categories based on relative distance from the study site to the southernmost limit of the species' geographic nesting range. (suny.edu)
By estimating these metabolic parameters through our advanced algorithms, GrAIg enables you to gain valuable insights into your athletes' physiological capabilities, adjust training programs, and optimize performance without the need for invasive and time-consuming lab tests. (graigcoach.com)

Currently, the improvement of detection modalities (i.e., direct detection of 13 C isotopomers), the progress in building adequate mathematical models along with the increase in magnetic field strength now available render possible detailed compartmentalized metabolic flux characterization. (frontiersin.org)
MTT analysis, PI/Annexin V staining, transwell and metabolic flux assays were performed to examine the effects of C1QBP on proliferation, apoptosis, migration, invasion, and oxidative phosphorylation of HCC cells. (jcancer.org)
Andersen et al suggested that this limitation results from glycolytic flux impairment, which causes a "metabolic bottleneck" in the tricarboxylic acid cycle. (medscape.com)

[ 2 ] Chronic hepatic inflammation, secondary to CLD, represents an early stage in the carcinogenesis process. (medscape.com)
The underlying molecular defect related to disordered mitochondrial function could represent a potential therapeutic target during the resolution of inflammation. (stanford.edu)

However, there has only been one previous functional study investigating MCT4 in glioblastoma (GBM) neurospheres, mainly focusing on tumor growth and survival dependent on the oxygen level [ 14 ]. (hindawi.com)
Notably, the former does not require oxygen, whereas mitochondrial energy production is dependent on oxygen. (nature.com)
S1P inhibited astrocytic glutamate uptake in a dose-dependent manner and increased mitochondrial oxygen consumption, primarily through S1P 2 . (eneuro.org)

In particular, direct 13 C MRS offers more detailed dataset acquisitions and provides information on metabolic interactions between neurons and astrocytes, and their role in supporting neurotransmission. (frontiersin.org)

We calculated hazard rate ratios (RRs) and their two-sided 95% confidence intervals (CIs) using Cox proportional hazard regression models with adjustment for age, sex, race/ethnicity, cigarette smoking, alcohol consumption, diabetes, and body mass index. (medscape.com)

BUN measurements are used in the diagnosis of certain renal and metabolic diseases. (cdc.gov)

EPOC, also known as oxygen debt, is the quantity of oxygen necessary to return your body to its normal. (exercisedaily.com)
Also known as the 'afterburn' effect, EPOC represents the period during which your body burns calories while at rest (aka while you're doing absolutely nothing) as it attempts to rebalance and return to homeostasis. (fitonapp.com)

Our results identify a naturally occurring variant of ATP5G1 from a mammalian hibernator that critically contributes to intrinsic cytoprotection against metabolic stress. (elifesciences.org)
3 The oxygen consumption of the mammalian retina (per gram of tissue) is nearly 50% greater than that of the kidney, three times greater than the cerebral cortex and six times that of cardiac muscle. (arn.org)

Key physiologic parameters that affect metabolic homeostasis include tissue blood flow, the balance between oxygen delivery and demand, and the oxygen content. (medscape.com)

Increased VO 2 apparently represents increased energy expenditure for thermogenesis, because VO 2 of mutant and normal mice does not differ at thermoneutral temperature. (johnshopkins.edu)
it is defined as the environmental temperature at which metabolic demands (and thus caloric expenditure) to maintain body temperature in the normal range (36.5 to 37.5° C rectal) are lowest. (msdmanuals.com)

However, consideration of the very high energy demands of the photoreceptor cells in the vertebrate retina suggests that rather than being a challenge to teleology the curious inverted design of the vertebrate retina may in fact represent a unique solution to the problem of providing the highly active photoreceptor cells of higher vertebrates with copious quantities of oxygen and nutrients. (arn.org)
Walls describes the photoreceptors in his classic The Vertebrate Eye as greedy, 6 and greedy they are for both nutrients and oxygen (See Fig. 2 ). (arn.org)

To use one liter of oxygen, the body expends roughly 5 calories of energy (a calorie is the amount of energy necessary to raise one liter of water one degree centigrade in temperature). (exercisedaily.com)
Even before temperature decreases, cold stress occurs when heat loss requires an increase in metabolic heat production. (msdmanuals.com)

DO2 depends on the amount of blood pumped per minute, or cardiac output (CO), and the arterial oxygen content of that blood (CaO2). (medscape.com)

The CaO2 depends on how much oxygen-carrying capacity is available, which is primarily a function of the hemoglobin (Hb) level and the arterial oxygen saturation (SaO2). (medscape.com)
This was associated with a higher bending stiffness as well as an increased number of CD31-positive microvessels and a higher oxygen saturation within the callus tissue. (bvsalud.org)

Circadian variations in microbiota function adds an extra layer of complexity to metabolic interactions between the host and the microbiota. (biorxiv.org)

The term hypoxia is used to describe biological situations where insufficient levels of oxygen exist. (mdpi.com)

Available evidence indicates that reduced GH signalling is linked to extended longevity by multiple interacting mechanisms including increased stress resistance, reduced growth, altered profiles of cytokines produced by the adipose tissue, and various metabolic adjustments such as enhanced insulin sensitivity, increased oxygen consumption (VO 2 /g) and reduced respiratory quotient. (johnshopkins.edu)
Available evidence indicates that reduced GH signalling is linked to extended longevity by multiple interacting mechanisms including increased stress resistance, reduced growth, altered profiles of cytokines produced by the adipose tissue, and various metabolic adjustments such as enhanced insulin sensitivity, increased oxygen consumption (VO2/g) and reduced respiratory quotient. (johnshopkins.edu)

Microbiota composition correlates with host metabolic health in both humans and mice. (biorxiv.org)
However, each group of mice have a distinctive circadian metabolic profile. (biorxiv.org)

2019). Akin to the dynamic nutrient requirements of the developing embryo, discrete in vitro cell states have distinct metabolic profiles (Zhou et al. (conditionmed.org)

This metabolic shift has the familiar symptoms we'd expect: lack of energy, low blood pressure, sensitivity to cold, and so on. (psychologytoday.com)

We discuss what is known about the distinct metabolic states captured in vitro by the 2-cell-like, naïve, blastocyst-like, formative, and primed states of pluripotency. (conditionmed.org)

2 This amplification process requires vast quantities of metabolic energy and consequently the photoreceptor layer has one of the highest metabolic rates of any known tissue. (arn.org)
Oxygen respiration, nutrient fluxes and excretion rates were determined. (mdpi.com)
Interestingly, MSCs showed enhanced glycolysis during challenge with cPE, but no significant changes in oxygen consumption rates (OCR). (stanford.edu)

Neonates have a metabolic response to cooling that involves chemical (nonshivering) thermogenesis by sympathetic nerve discharge of norepinephrine in the brown fat. (msdmanuals.com)

Mechanisms that deserve study include inhalation, child consumption of paint chips and other building materials, accumulation in food, accumulation in fish, occupational exposures, for example, during building demolition. (cdc.gov)

He found that, even in the presence of ample oxygen, cancer cells prefer to metabolize glucose by glycolysis, a seeming paradox as glycolysis, when compared to oxidative phosphorylation, is a less efficient pathway for producing ATP (Warburg, 1956). (pharmaceuticalintelligence.com)
Loss of p53 may also recapitulate the features of the Warburg effect, that is, the uncoupling of glycolysis from oxygen levels. (pharmaceuticalintelligence.com)

569 Poisoning Associated with Consumption of a included in national and median calculations. (cdc.gov)

This basic survey is pointed toward evaluating accessible proof on the jobs of supplements, food and dietary regimens in energy admission and energy consumption. (alliedacademies.org)
A couple of food varieties show useful consequences for digestion and energy consumption, as the human energy balance is intricate and multifactorial. (alliedacademies.org)
Online entertainment, the Web, television and magazines regularly propose direct-to-buyer 'data' about food, dietary plans or enhancements which increment the energy consumption and additionally consume fats or, in any case, diminish the energy use and lead to fat amassing [ 1 ]. (alliedacademies.org)

This reaction increases the metabolic rate and oxygen consumption 2- to 3-fold. (msdmanuals.com)

FCCP uncouples oxygen consumption from ATP production, restores the mitochondrial membrane potential because of depolarizing this membrane, leading to the maximization of OXPHOS. (antiviralbiologic.com)
36.5° C, there may be cold stress at higher temperatures whenever heat loss requires an increase in metabolic heat production. (msdmanuals.com)

Most of the literature on the beneficial health outcomes of fiber consumption comes from population-level epidemiological studies relying on self-reported fiber intake levels. (undergroundnutritionnj.com)

But, it is unclear how their cells are able to endure this metabolic stress. (elifesciences.org)

INTRODUCTION: Baby boomers, people born from 1946 through 1964, represent a substantial portion of the US population. (cdc.gov)

One such animal is the Arctic ground squirrel, an extreme hibernator that can drop its body temperatures to below 0°C. This hibernation ability means the cells of Arctic ground squirrels can survive severe shortages of blood and oxygen. (elifesciences.org)
At long last, micro biota may disrupt the admission, use and consumption of energy in the human body. (alliedacademies.org)
How quickly does the body start to ramp up the metabolic rate again in order to restore the body to optimal functioning, and how much does it play things safe in case energy availability drops off again? (psychologytoday.com)

Anatomy16

Organisms12

Diseases9

Chemicals and Drugs78

Analytical, Diagnostic and Therapeutic Techniques and Equipment52

Psychiatry and Psychology9

Phenomena and Processes79

Anthropology, Education, Sociology and Social Phenomena10

Technology, Industry, Agriculture20

Information Science1

Health Care23

Pathways10

METs5

Equivalents1

Basal meta3

Mitochondrial oxygen consumption rates2

Resting meta9

Reactive6

Glucose consumption2

Metabolism12

Neurodegenerative3

High metabolic3

Defects2

Derangements2

Mitochondria5

Pathophysiology1

Processes1

Syndrome3

Maximal4

Aerobic3

Induce1

Proteins2

Cellular3

Excess7

Assay1

Amount of oxygen2

Activity7

Lactate2

Intensity5

Disorders3

Carbon4

Physiological3

Flux3

Inflammation2

Dependent3

Astrocytes1

Diabetes1

Renal1

EPOC2

Mammalian2

Homeostasis1

Expenditure2

Nutrients2

Temperature2

Cardiac1

Saturation2

Interactions1

Hypoxia1

Cytokines2

Mice2

Profiles1

Shift1

Vitro1

Rates3

Thermogenesis1

Accumulation1

Glycolysis2

Calculations1

Energy consumption3

Increases1

Production2

Beneficial1

Unclear1

Substantial1

Body3